RGD-dependent integrins are mechanotransducers in dynamically compressed tissue-engineered cartilage constructs

Journal of Biomechanics

Volumn 42, Issue 13, 2009, Pages 2177-2182

  Kock, Linda M ^a,b   Schulz, Ronny M ^b   van Donkelaar, Corrinus C ^a   Thümmler, Christian B ^b   Bader, Augustinus ^b   Ito, Keita ^a  

^a EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Cartilage; Chondrocytes; Gene expression; Mechanical stimulation; Mechanotransduction; Tissue engineering

Indexed keywords

AGAROSE; APPLIED LOADING; ARTICULAR CARTILAGES; CHONDROCYTES; COLLAGEN II; ECM PROTEINS; INTEGRIN RECEPTORS; INTEGRINS; MATRIX; MECHANICAL STIMULATION; MECHANORECEPTORS; MECHANOTRANSDUCTION; MRNA LEVEL; SEMI-QUANTITATIVE; TIME POINTS; TISSUE ENGINEERED CARTILAGE;

BIOACTIVITY; BIOSYNTHESIS; BODY FLUIDS; COLLAGEN; COMPOSITE BRIDGES; ELECTRIC DISCHARGE MACHINING; GENE EXPRESSION; GLYCOPROTEINS; LIGAMENTS; LOADING; NUCLEIC ACIDS; TISSUE ENGINEERING; ULSI CIRCUITS; ULTRASONIC MEASUREMENT;

CARTILAGE;

AGAROSE; AGGRECAN; ARGINYLGLYCYLASPARTIC ACID; COLLAGEN TYPE 2; CYCLOPEPTIDE; INTEGRIN; INTEGRIN RECEPTOR; MESSENGER RNA; STROMELYSIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BIOSYNTHESIS; CARTILAGE CELL; CELL ISOLATION; COMPRESSION; DNA CONTENT; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE EXPRESSION REGULATION; MECHANICAL STRESS; MECHANORECEPTOR; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; TISSUE ENGINEERING; TRANSDUCER; TRINUCLEOTIDE REPEAT;

ANIMALS; CARTILAGE, ARTICULAR; CATTLE; CELLS, CULTURED; CHONDROCYTES; COMPRESSIVE STRENGTH; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; INTEGRINS; MECHANOTRANSDUCTION, CELLULAR; OLIGOPEPTIDES; STRESS, MECHANICAL; TISSUE ENGINEERING;

EID: 69449084642     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2009.05.039     Document Type: Article

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