Effect of alkyl substitution at the amide nitrogen on amide bond cleavage: Electrospray ionization/surface-induced dissociation fragmentation of substance P and two alkylated analogs

Journal of Mass Spectrometry

Volumn 31, Issue 10, 1996, Pages 1141-1148

  Nair, Hari ^a   Somogyi, Árpád ^a,c   Wysocki, Vicki H ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b The University of Arizona   (United States)

^c CTRL RES INSTITUTE FOR CHEMISTRY   (Hungary)

Author keywords

Ab initio calculations; Amide N alkylation; Peptide fragmentation mechanisms; Surface induced dissociation; Thermal dissociation

Indexed keywords

SUBSTANCE P; SUBSTANCE P [9 PROLINE]; SUBSTANCE P [9 SARCOSINE]; SUBSTANCE P DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CALCULATION; DRUG STRUCTURE; IN VITRO STUDY; MASS SPECTROMETRY; PRIORITY JOURNAL; THEORY;

ALKYLATION; AMIDES; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; NITROGEN; SUBSTANCE P;

EID: 0029824087     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9888(199610)31:10<1141::AID-JMS402>3.0.CO;2-N     Document Type: Article

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