Light irradiation increases embryotoxicity of photodynamic therapy sensitizers (5-aminolevulinic acid and protoporphyrin IX) in chick embryos

Reproductive Toxicology

Volumn 15, Issue 2, 2001, Pages 111-116

  Peterka, Miroslav ^a   Klepáček, Ivo ^b  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Chick; Cleft beak; Embryotoxicity; Gastroschisis; Lethality; Liposome; Malformation; Strait jacket

Indexed keywords

AMINOLEVULINIC ACID; LIPOSOME; PHOTOSENSITIZING AGENT; PROTOPORPHYRIN;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHICK EMBRYO; CONGENITAL MALFORMATION; CONTROLLED STUDY; DARKNESS; DOSE RESPONSE; EMBRYO; EMBRYO DEATH; EMBRYOTOXICITY; GASTROSCHISIS; IRRADIATION; LETHALITY; LIGHT; NONHUMAN; PHOTODYNAMIC THERAPY; TERATOGENICITY;

ABNORMALITIES, DRUG-INDUCED; AMINOLEVULINIC ACID; ANIMALS; CHICK EMBRYO; DARKNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO LOSS; LIGHT; LIPOSOMES; PHOTOSENSITIZING AGENTS; PROTOPORPHYRINS;

EID: 0035032417     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(01)00119-8     Document Type: Article

References (51)

1. Photodynamic therapy (PDT) of malignant tumours
2. 5-Aminolevulinic acid-based photodynamic therapy. Clinical research and future challenges
3. Photochemotherapy of cancer: Experimental research
4. Photodynamic therapy
5. Photodynamic therapy
6. Does δ-aminolaevulinic acid induce genotoxic effects?
7. Photodynamic therapy with endogenous protoporphyrin IX: Basic principles and present clinical experience
8. Photodynamic therapy utilising topical δ-aminolevulinic acid in non-melanoma skin malignancies of the eyelid and the periocular skin
9. Kinetic fluorescence studies of 5-aminolaevulinic acid-induced protoporphyrin IX accumulation in basal cell carcinomas
10. Photodetection of early human bladder cancer based on the fluorescence of 5-aminolaevulic acid hexylester-induced protoporphyrin IX: A pilot study
11. 5-Aminolaevulinic acid-induced fluorescence endoscopy applied at secondary transurethral resection after conventional resection of primary superficial blader tumors
12. Diagnosis of bladder carcinoma using protoporphyrin IX fluorescence induced by 5-aminolaevulinic acid
13. Is everything all right if nothing seems wrong? A simple method of assessing the diagnostic value of endoscopic procedures when a gold standard is absent
14. Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy
15. Photodynamic diagnosis of gastrointestinal precancerous lesion after sensitization with 5-aminolevulinic acid. A pilot study
16. 5-Aminolevulinic acid photosensitization of dysplastic Barrett's esophagus: A pharmacokinetic study
17. New photosensitizers for photodynamic therapy in gastroenterology
18. Phototransformations of 5-aminolevulic acid-induced protoporfirin IX in vitro: A spectroscopic study
19. Photodynamic diagnosis of urothelial neoplasms after intravesicular instillation of 5-aminolevulinic acid
20. Integral photodynamic treatment of refractory superficial bladder cancer
21. Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence
22. Side effects and photosensitization of human tissues after aminolevulinic acid
23. Vascular damage during PDT as monitored in the chick chorioallantoic membrane
24. In vivo damage to chorioallantoic membrane blood vessels by porphycene-induced photodynamic therapy
25. In vitro and in vivo photosensitizing capabilities of 5-ALA in vascular endothelial cells
26. Systemic application of photosensitizers in the chick chorioallantoic membrane (CAM) model: Photodynamic response of CAM vessels and 5-aminolevulinic acid uptake kinetics by transplantable tumors
27. The chick embryotoxicity screening test (CHEST)
28. Dose-response relationships in chick embryos exposed to embryotoxic agents
29. Embryotoxicity of 25 psychotropic drugs: A study using CHEST
30. Embryotoxicity of nine seed mordants in the chick embryo -the CHEST method
31. Different embryotoxic effect of vitamin A and B-Carotene detected in the chick embryo
32. Teratogenic and lethal effects of long-term hyperthermia and hypothermia in the chick embryo
33. Hyperthermia in the chick embryo: HSP and possible mechanisms of developmental defects
34. Distribution of heat shock protein 108 mRNA in the chicken central nervous system
35. Drug delivery systems. I. Site-specific drug delivery using liposomes as carriers
36. Meso-tetraphenylporphin in liposomes as a suitable photosensitizer for photodynamic therapy of tumors
37. A series of normal stages in the development of the chick embryo
38. Preclinical study in cats of the pro-photosensitizers 5-aminolevulinic acid
39. Detection of early stages of carcinogenesis in adenomas of murine lung by 5-aminolevulinic acid-induced protoporphyrin IX fluorescence
40. In vitro study of biosynthesis of protoporphyrin IX induced by δ-aminolevulinic acid in normal and cancerous cells of the human cervix
41. Rodent fibroblast model for studies of response of malignant cells to exogenous 5-aminiolevulinic acid
42. Protoporphyrin IX accumulation in cells treated with 5-aminolevulinic acid: Dependence on cell density, cell size, and cell cycle
43. 5-Aminolaevulinic acid-induced protoporphyrin IX accumulation in tissues: Pharmacokinetics after oral or intravenous administration
44. The importance of fluorescence distribution and kinetics of ALA-induced PpIX in the bladder in photodynamic therapy
45. The morphological changes in rat bladder after photodynamic therapy induced with 5-aminolaevulinic acid-induced protoporphyrin IX
46. Biodistribution of protoporphyrin IX in rat urinary bladder after intravesical instillation of 5-aminolevulinic acid
47. The "strait jacket" syndrome in the chick. II. Mechanism of development
48. Cleft beak induced by hydrocortisone in the chick is prevented by increased cell division after experimental reduction of amniotic fluid
49. Expression of the functional neurotransmitter receptor in an uninnervated tissue: Avian amnion
50. Studies of in vitro cultivated cells from the smooth muscle organs. 3. Effectiveness of some drugs on pulsation frequency of isolated smooth muscle cells of the chicken amnion