Application of α-chloroaldoxime O-methanesulfonates to one-pot synthesis of N,N′,N″-substituted guanidines via Tiemann rearrangement

Tetrahedron Letters

Volumn 50, Issue 42, 2009, Pages 5813-5815

  Yamamoto, Yuhei ^a   Mizuno, Hiroo ^a   Tsuritani, Takayuki ^a   Mase, Toshiaki ^a  

^a BANYU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Chloroaldoxime O methanesulfonates; Carbodiimides; Guanidines; Tiemann rearrangement

Indexed keywords

ALIPHATIC AMINE; ALPHA CHLOROALDOXIME O METHANESULFONATE DERIVATIVE; CYANAMIDE; GUANIDINE DERIVATIVE; MESYLIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; ONE POT SYNTHESIS; REACTION ANALYSIS; TIEMANN REARRANGEMENT;

EID: 69249248209     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.07.147     Document Type: Article

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40. nBu-substituted α-chloroaldoxime methanesulfonate with benzylamine gave only the corresponding amidoxime O-methanesulfonate, and no rearrangement occurred under our reaction conditions.