A convenient method for the synthesis of 2-amino substituted aza-heterocycles from N,N′-disubstituted thioureas using TsCl/NaOH

Tetrahedron

Volumn 60, Issue 44, 2004, Pages 9883-9888

  Heinelt, Uwe ^a   Schultheis, Daniela ^a   Jäger, Siegfried ^a   Lindenmaier, Marion ^a   Pollex, Annett ^a   Beckmann, Henning S G ^a  

^a Industrialpark H

Author keywords

Cyclodesulfurisation; Heterocycle synthesis; Ring closure; Thiourea; TsCl NaOH

Indexed keywords

(1H BENZOIMIDAZOL 2 YL)CYCLOHEXYLAMINE; (2,6 DICHLOROPHENYL)(OCTAHYDROBENZ[D][1,3]OXAZIN 2 YLIDENE)AMINE; (2,6 DICHLOROPHENYL)(OCTAHYDROBENZO[E][1,3]OXAZIN 2 YLIDENE)AMINE; (4,4 DIMETHYLOXAZOLIDIN 2 YLIDENE)PYRIDIN 3 YLAMINE; (5 METHYLOXAZOLIDIN 2 YLIDENE)PHENYLAMINE; [1,3]OXAZINAN 2 YLIDENE PHENYLAMINE; BENZOXAZOL 2 YLPHENYLAMINE; CLONIDINE DERIVATIVE; HETEROCYCLIC COMPOUND; OXAZOLIDIN 2 YLIDENE PYRIDIN 3 YLAMINE; PHENYLTHIAZOLIDIN 2 YLIDENAMINE; POLYMER; REAGENT; SODIUM HYDROXIDE; THIOUREA DERIVATIVE; TOLUENE DERIVATIVE; TOLUENESULFONYL CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; PRIORITY JOURNAL; SUBSTITUTION REACTION;

EID: 4644226156     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2004.08.031     Document Type: Article

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