TGF-β induces degradation of TAL1/SCL by the ubiquitin-proteasome pathway through AKT-mediated phosphorylation

Blood

Volumn 113, Issue 26, 2009, Pages 6695-6698

  Terme, Jean Michel ^a   Lhermitte, Ludovic ^b   Asnafi, Vahid ^b   Jalinot, Pierre ^a  

^a UNIVERSITÉ DE LYON   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEASOME; THREONINE; TRANSCRIPTION FACTOR TAL1; TRANSFORMING GROWTH FACTOR BETA; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; AKT1 PROTEIN, HUMAN; ANDROSTANE DERIVATIVE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BENZYLOXYCARBONYLLEUCYL LEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; LEUPEPTIN; ONCOPROTEIN; PHOSPHOTHREONINE; PROTEIN KINASE B; STUB1 PROTEIN, HUMAN; T CELL FACTOR 3; T CELL FACTOR PROTEIN; TAL1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR PROTEIN; UBIQUITIN PROTEIN LIGASE; WORTMANNIN;

ARTICLE; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOPRECIPITATION; LEUKEMIA; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; AMINO ACID SUBSTITUTION; DRUG ANTAGONISM; HELA CELL; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN PROCESSING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SUBSTITUTION; ANDROSTADIENES; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; DIMERIZATION; HELA CELLS; HUMANS; JURKAT CELLS; LEUPEPTINS; NEOPLASM PROTEINS; PHOSPHORYLATION; PHOSPHOTHREONINE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN INTERACTION MAPPING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; TCF TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA1; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 69249238114     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-07-166835     Document Type: Article

References (25)

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