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Volumn 108, Issue 3, 2006, Pages 986-992

Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

HETERODIMER; TAL1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2A; UNCLASSIFIED DRUG;

EID: 33746656195     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2005-08-3482     Document Type: Article
Times cited : (63)

References (42)
  • 1
    • 0030581174 scopus 로고    scopus 로고
    • The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages
    • Porcher C, Swat W, Rockwell K, Fujiwara Y, Alt FW, Orkin SH. The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages. Cell. 1996;86:47-57.
    • (1996) Cell , vol.86 , pp. 47-57
    • Porcher, C.1    Swat, W.2    Rockwell, K.3    Fujiwara, Y.4    Alt, F.W.5    Orkin, S.H.6
  • 2
    • 0031194883 scopus 로고    scopus 로고
    • The SCL/TAL1 gene: Roles in normal and malignant haematopoiesis
    • Robb L, Begley CG. The SCL/TAL1 gene: roles in normal and malignant haematopoiesis. Bioessays. 1997;19:607-613.
    • (1997) Bioessays , vol.19 , pp. 607-613
    • Robb, L.1    Begley, C.G.2
  • 3
    • 17144474314 scopus 로고    scopus 로고
    • Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
    • Ferrando AA, Neuberg DS, Staunton J, et al. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell. 2002;1:75-87.
    • (2002) Cancer Cell , vol.1 , pp. 75-87
    • Ferrando, A.A.1    Neuberg, D.S.2    Staunton, J.3
  • 4
    • 10744222734 scopus 로고    scopus 로고
    • Prognostic importance of TLX1 (HOX11) oncogene expression in adults with T-cell acute lymphoblastic leukaemia
    • Ferrando AA, Neuberg DS, Dodge RK, et al. Prognostic importance of TLX1 (HOX11) oncogene expression in adults with T-cell acute lymphoblastic leukaemia. Lancet. 2004;363:535-536.
    • (2004) Lancet , vol.363 , pp. 535-536
    • Ferrando, A.A.1    Neuberg, D.S.2    Dodge, R.K.3
  • 5
    • 1442307956 scopus 로고    scopus 로고
    • Biallelic transcriptional activation of oncogenic transcription factors in T-cell acute lymphoblastic leukemia
    • Ferrando AA, Herblot S, Palomero T, et al. Biallelic transcriptional activation of oncogenic transcription factors in T-cell acute lymphoblastic leukemia. Blood. 2004;103:1909-1911.
    • (2004) Blood , vol.103 , pp. 1909-1911
    • Ferrando, A.A.1    Herblot, S.2    Palomero, T.3
  • 6
    • 0029073944 scopus 로고
    • Does activation of the TAL1 gene occur in a majority of patients with T-cell acute lymphoblastic leukemia? A pediatric oncology group study
    • Bash RO, Hall S, Timmons CF, et al. Does activation of the TAL1 gene occur in a majority of patients with T-cell acute lymphoblastic leukemia? A pediatric oncology group study. Blood. 1995;86:666-676.
    • (1995) Blood , vol.86 , pp. 666-676
    • Bash, R.O.1    Hall, S.2    Timmons, C.F.3
  • 7
    • 0028276834 scopus 로고
    • The E2A and tal-1 helix-loop-helix proteins associate in vivo and are modulated by Id proteins during interleukin 6-induced myeloid differentiation
    • Voronova AF, Lee F. The E2A and tal-1 helix-loop-helix proteins associate in vivo and are modulated by Id proteins during interleukin 6-induced myeloid differentiation. Proc Natl Acad Sci U S A. 1994;91:5952-5956.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 5952-5956
    • Voronova, A.F.1    Lee, F.2
  • 8
    • 2942579675 scopus 로고    scopus 로고
    • TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB
    • O'Neil J, Shank J, Cusson N, Murre C, Kelliher M. TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB. Cancer Cell. 2004;5:587-596.
    • (2004) Cancer Cell , vol.5 , pp. 587-596
    • O'Neil, J.1    Shank, J.2    Cusson, N.3    Murre, C.4    Kelliher, M.5
  • 9
    • 0028348648 scopus 로고
    • Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells
    • Hsu HL, Wadman I, Baer R. Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells. Proc Natl Acad Sci U S A. 1994;91:3181-3185.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 3181-3185
    • Hsu, H.L.1    Wadman, I.2    Baer, R.3
  • 10
    • 0025804491 scopus 로고
    • Enhancer-binding activity of the tal-1 oncoprotein in association with the E47/E12 helix-loop-helix proteins
    • Hsu HL, Cheng JT, Chen Q, Baer R. Enhancer-binding activity of the tal-1 oncoprotein in association with the E47/E12 helix-loop-helix proteins. Mol Cell Biol. 1991;11:3037-3042.
    • (1991) Mol Cell Biol , vol.11 , pp. 3037-3042
    • Hsu, H.L.1    Cheng, J.T.2    Chen, Q.3    Baer, R.4
  • 11
    • 0030752361 scopus 로고    scopus 로고
    • E2A deficiency leads to abnormalities in alpha-beta T-cell development and to rapid development of T-cell lymphomas
    • Bain G, Engel I, Robanus Maandag EC, et al. E2A deficiency leads to abnormalities in alpha-beta T-cell development and to rapid development of T-cell lymphomas. Mol Cell Biol. 1997;17:4782-4791.
    • (1997) Mol Cell Biol , vol.17 , pp. 4782-4791
    • Bain, G.1    Engel, I.2    Robanus Maandag, E.C.3
  • 12
    • 0032549655 scopus 로고    scopus 로고
    • The Tal1 oncoprotein inhibits E47-mediated transcription: Mechanism of inhibition
    • Park ST, Sun XH. The Tal1 oncoprotein inhibits E47-mediated transcription: mechanism of inhibition. J Biol Chem. 1998;273:7030-7037.
    • (1998) J Biol Chem , vol.273 , pp. 7030-7037
    • Park, S.T.1    Sun, X.H.2
  • 13
    • 0031724589 scopus 로고    scopus 로고
    • TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3
    • Ono Y, Fukuhara N, Yoshie O. TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3. Mol Cell Biol. 1998;18:6939-6950.
    • (1998) Mol Cell Biol , vol.18 , pp. 6939-6950
    • Ono, Y.1    Fukuhara, N.2    Yoshie, O.3
  • 14
    • 0036785404 scopus 로고    scopus 로고
    • The SCL complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1
    • Lecuyer E, Herblot S, Saint-Denis M, et al. The SCL complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1. Blood. 2002;100:2430-2440.
    • (2002) Blood , vol.100 , pp. 2430-2440
    • Lecuyer, E.1    Herblot, S.2    Saint-Denis, M.3
  • 15
    • 0842304226 scopus 로고    scopus 로고
    • SCL assembles a multifactorial complex that determines glycophorin A expression
    • Lahlil R, Lecuyer E, Herblot S, Hoang T. SCL assembles a multifactorial complex that determines glycophorin A expression. Mol Cell Biol. 2004;24:1439-1452.
    • (2004) Mol Cell Biol , vol.24 , pp. 1439-1452
    • Lahlil, R.1    Lecuyer, E.2    Herblot, S.3    Hoang, T.4
  • 16
    • 0142091497 scopus 로고    scopus 로고
    • Identification of a TAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 in erythroid gene expression and differentiation
    • Xu Z, Huang S, Chang LS, Agulnick AD, Brandt SJ. Identification of a TAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 in erythroid gene expression and differentiation. Mol Cell Biol. 2003;23:7585-7599.
    • (2003) Mol Cell Biol , vol.23 , pp. 7585-7599
    • Xu, Z.1    Huang, S.2    Chang, L.S.3    Agulnick, A.D.4    Brandt, S.J.5
  • 17
    • 0038805207 scopus 로고    scopus 로고
    • Regulation of pT alpha gene expression by a dosage of E2A, HEB, and SCL
    • Tremblay M, Herblot S, Lecuyer E, Hoang T. Regulation of pT alpha gene expression by a dosage of E2A, HEB, and SCL. J Biol Chem. 2003;278:12680-12687.
    • (2003) J Biol Chem , vol.278 , pp. 12680-12687
    • Tremblay, M.1    Herblot, S.2    Lecuyer, E.3    Hoang, T.4
  • 18
    • 0034252945 scopus 로고    scopus 로고
    • SCL and LMO1 alter thymocyte differentiation: Inhibition of E2A-HEB function and pre-T alpha chain expression
    • Herblot S, Steff AM, Hugo P, Aplan PD, Hoang T. SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain expression. Nat Immunol. 2000;1:138-144.
    • (2000) Nat Immunol , vol.1 , pp. 138-144
    • Herblot, S.1    Steff, A.M.2    Hugo, P.3    Aplan, P.D.4    Hoang, T.5
  • 19
    • 0344926374 scopus 로고    scopus 로고
    • The basic helix-loop-helix transcription factor TAL1/SCL inhibits the expression of the p16INK4A and pTalpha genes
    • Hansson A, Manetopoulos C, Jonsson JI, Axelson H. The basic helix-loop-helix transcription factor TAL1/SCL inhibits the expression of the p16INK4A and pTalpha genes. Biochem Biophys Res Commun. 2003;312:1073-1081.
    • (2003) Biochem Biophys Res Commun , vol.312 , pp. 1073-1081
    • Hansson, A.1    Manetopoulos, C.2    Jonsson, J.I.3    Axelson, H.4
  • 20
    • 0037080483 scopus 로고    scopus 로고
    • E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints
    • Ren B, Cam H, Takahashi Y, et al. E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints. Genes Dev. 2002;16:245-256.
    • (2002) Genes Dev , vol.16 , pp. 245-256
    • Ren, B.1    Cam, H.2    Takahashi, Y.3
  • 21
    • 10744227070 scopus 로고    scopus 로고
    • Control of pancreas and liver gene expression by HNF transcription factors
    • Odom DT, Zizlsperger N, Gordon DB, et al. Control of pancreas and liver gene expression by HNF transcription factors. Science. 2004;303:1378-1381.
    • (2004) Science , vol.303 , pp. 1378-1381
    • Odom, D.T.1    Zizlsperger, N.2    Gordon, D.B.3
  • 23
    • 0037435010 scopus 로고    scopus 로고
    • Identification of novel pRb binding sites using CpG microarrays suggests that E2F recruits pRb to specific genomic sites during S phase
    • Wells J, Yan PS, Cechvala M, Huang T, Farnham PJ. Identification of novel pRb binding sites using CpG microarrays suggests that E2F recruits pRb to specific genomic sites during S phase. Oncogene. 2003;22:1445-1460.
    • (2003) Oncogene , vol.22 , pp. 1445-1460
    • Wells, J.1    Yan, P.S.2    Cechvala, M.3    Huang, T.4    Farnham, P.J.5
  • 24
    • 0037080674 scopus 로고    scopus 로고
    • Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis
    • Weinmann AS, Yan PS, Oberley MJ, Huang TH, Farnham PJ. Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis. Genes Dev. 2002;16:235-244.
    • (2002) Genes Dev , vol.16 , pp. 235-244
    • Weinmann, A.S.1    Yan, P.S.2    Oberley, M.J.3    Huang, T.H.4    Farnham, P.J.5
  • 25
    • 1842531473 scopus 로고    scopus 로고
    • The bHLH TAL-1/SCL regulates endothelial cell migration and morphogenesis
    • Lazrak M, Deleuze V, Noel D, et al. The bHLH TAL-1/SCL regulates endothelial cell migration and morphogenesis. J Cell Sci. 2004;117:1161-1171.
    • (2004) J Cell Sci , vol.117 , pp. 1161-1171
    • Lazrak, M.1    Deleuze, V.2    Noel, D.3
  • 26
    • 0029009244 scopus 로고
    • Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain
    • Bernard M, Smit L, Macintyre E, Matthieu-Mahul D, Pulford K. Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain. Blood. 1995;85:3356-3357.
    • (1995) Blood , vol.85 , pp. 3356-3357
    • Bernard, M.1    Smit, L.2    Macintyre, E.3    Matthieu-Mahul, D.4    Pulford, K.5
  • 27
    • 0027480618 scopus 로고
    • Products of the TAL1 oncogene: Basic helix-loop-helix proteins phosphorylated at serine residues
    • Cheng JT, Hsu HL, Hwang LY, Baer R. Products of the TAL1 oncogene: basic helix-loop-helix proteins phosphorylated at serine residues. Oncogene. 1993;8:677-683.
    • (1993) Oncogene , vol.8 , pp. 677-683
    • Cheng, J.T.1    Hsu, H.L.2    Hwang, L.Y.3    Baer, R.4
  • 28
    • 0028219456 scopus 로고
    • DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein
    • Inaba T, Shapiro LH, Funabiki T, et al. DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein. Mol Cell Biol. 1994;14:3403-3413.
    • (1994) Mol Cell Biol , vol.14 , pp. 3403-3413
    • Inaba, T.1    Shapiro, L.H.2    Funabiki, T.3
  • 29
    • 0034616930 scopus 로고    scopus 로고
    • Functional discovery via a compendium of expression profiles
    • Hughes TR, Marton MJ, Jones AR, et al. Functional discovery via a compendium of expression profiles. Cell. 2000;102:109-126.
    • (2000) Cell , vol.102 , pp. 109-126
    • Hughes, T.R.1    Marton, M.J.2    Jones, A.R.3
  • 30
    • 0037174671 scopus 로고    scopus 로고
    • Transcriptional regulatory networks in Saccharomyces cerevisiae
    • Lee TI, Rinaldi NJ, Robert F, et al. Transcriptional regulatory networks in Saccharomyces cerevisiae. Science. 2002;298:799-804.
    • (2002) Science , vol.298 , pp. 799-804
    • Lee, T.I.1    Rinaldi, N.J.2    Robert, F.3
  • 31
    • 0030999645 scopus 로고    scopus 로고
    • The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins
    • Wadman IA, Osada H, Grutz GG, et al. The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins. EMBO J. 1997;16:3145-3157.
    • (1997) EMBO J , vol.16 , pp. 3145-3157
    • Wadman, I.A.1    Osada, H.2    Grutz, G.G.3
  • 32
    • 0029906182 scopus 로고    scopus 로고
    • E-box sequence and context-dependent TAL1/SCL modulation of basic helix-loop-helix protein-mediated transcriptional activation
    • Nielsen AL, Norby PL, Pedersen FS, Jorgensen P. E-box sequence and context-dependent TAL1/SCL modulation of basic helix-loop-helix protein-mediated transcriptional activation. J Biol Chem. 1996;271:31463-31469.
    • (1996) J Biol Chem , vol.271 , pp. 31463-31469
    • Nielsen, A.L.1    Norby, P.L.2    Pedersen, F.S.3    Jorgensen, P.4
  • 33
    • 0030066615 scopus 로고    scopus 로고
    • Determinants of helix-loop-helix dimerization affinity: Random mutational analysis of SCL/tal
    • Goldfarb AN, Lewandowska K, Shoham M. Determinants of helix-loop-helix dimerization affinity: random mutational analysis of SCL/tal. J Biol Chem. 1996;271:2683-2688.
    • (1996) J Biol Chem , vol.271 , pp. 2683-2688
    • Goldfarb, A.N.1    Lewandowska, K.2    Shoham, M.3
  • 34
    • 8844285956 scopus 로고    scopus 로고
    • Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress
    • Hayakawa J, Mittal S, Wang Y, et al. Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress. Mol Cell. 2004;16:521-535.
    • (2004) Mol Cell , vol.16 , pp. 521-535
    • Hayakawa, J.1    Mittal, S.2    Wang, Y.3
  • 35
    • 19944367254 scopus 로고    scopus 로고
    • Defining the CREB regulon: A genome-wide analysis of transcription factor regulatory regions
    • Impey S, McCorkle SR, Cha-Molstad H, et al. Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions. Cell. 2004;119:1041-1054.
    • (2004) Cell , vol.119 , pp. 1041-1054
    • Impey, S.1    McCorkle, S.R.2    Cha-Molstad, H.3
  • 36
    • 20144379523 scopus 로고    scopus 로고
    • Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues
    • Zhang X, Odom DT, Koo SH, et al. Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proc Natl Acad Sci U S A. 2005;102:4459-4464.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 4459-4464
    • Zhang, X.1    Odom, D.T.2    Koo, S.H.3
  • 37
    • 47249142028 scopus 로고    scopus 로고
    • Glucocorticoid receptor-dependent gene regulatory networks
    • Phuc Le P, Friedman JR, Schug J, et al. Glucocorticoid receptor-dependent gene regulatory networks. PLoS Genet. 2005;1:e16.
    • (2005) PLoS Genet , vol.1
    • Phuc Le, P.1    Friedman, J.R.2    Schug, J.3
  • 38
    • 0028954462 scopus 로고
    • Inhibition of cellular differentiation by the SCL/tal oncoprotein: Transcriptional repression by an Id-like mechanism
    • Goldfarb AN, Lewandowska K. Inhibition of cellular differentiation by the SCL/tal oncoprotein: transcriptional repression by an Id-like mechanism. Blood. 1995;85:465-471.
    • (1995) Blood , vol.85 , pp. 465-471
    • Goldfarb, A.N.1    Lewandowska, K.2
  • 39
    • 0028290697 scopus 로고
    • Positive and negative transcriptional control by the TAL1 helix-loop-helix protein
    • Hsu HL, Wadman I, Tsan JT, Baer R. Positive and negative transcriptional control by the TAL1 helix-loop-helix protein. Proc Natl Acad Sci U S A. 1994;91:5947-5951.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 5947-5951
    • Hsu, H.L.1    Wadman, I.2    Tsan, J.T.3    Baer, R.4
  • 40
    • 0033043388 scopus 로고    scopus 로고
    • Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: Parallels with E2A-deficient mice
    • Chervinsky DS, Zhao XF, Lam DH, Ellsworth M, Gross KW, Aplan PD. Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient mice. Mol Cell Biol. 1999;19:5025-5035.
    • (1999) Mol Cell Biol , vol.19 , pp. 5025-5035
    • Chervinsky, D.S.1    Zhao, X.F.2    Lam, D.H.3    Ellsworth, M.4    Gross, K.W.5    Aplan, P.D.6
  • 41
    • 0032569833 scopus 로고    scopus 로고
    • Identification of the LMO4 gene encoding an interaction partner of the LIM-binding protein LDB1/NLI1: A candidate for displacement by LMO proteins in T cell acute leukaemia
    • Grutz G, Forster A, Rabbitts TH. Identification of the LMO4 gene encoding an interaction partner of the LIM-binding protein LDB1/NLI1: a candidate for displacement by LMO proteins in T cell acute leukaemia. Oncogene. 1998;17:2799-2803.
    • (1998) Oncogene , vol.17 , pp. 2799-2803
    • Grutz, G.1    Forster, A.2    Rabbitts, T.H.3
  • 42
    • 0027973545 scopus 로고
    • Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia
    • Wadman I, Li J, Bash RO, et al. Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia. EMBO J. 1994;13:4831-4839.
    • (1994) EMBO J , vol.13 , pp. 4831-4839
    • Wadman, I.1    Li, J.2    Bash, R.O.3


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