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Volumn 132, Issue 3, 2009, Pages 281-291

Quantitative electron microscopy shows uniform incorporation of triglycerides into existing lipid droplets

Author keywords

Adipocyte; Cholesterol ester; Electron microscopy; Lipid droplet; Triglyceride

Indexed keywords

FAT DROPLET; OSMIUM TETRAOXIDE; PHOSPHOLIPID; TRIACYLGLYCEROL;

EID: 69249230777     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-009-0615-z     Document Type: Article
Times cited : (63)

References (36)
  • 1
    • 0014187525 scopus 로고
    • Osmium tetroxide as a histochemical and histological reagent
    • CW Adams YH Abdulla OB Bayliss 1967 Osmium tetroxide as a histochemical and histological reagent Histochemie 9 68 77
    • (1967) Histochemie , vol.9 , pp. 68-77
    • Adams, C.W.1    Abdulla, Y.H.2    Bayliss, O.B.3
  • 4
    • 0022447314 scopus 로고
    • Effect of monensin and nocodazole on the intestinal lipid esterification in mouse jejunal organ culture
    • H Carlier A Bernard JS Hugon 1986 Effect of monensin and nocodazole on the intestinal lipid esterification in mouse jejunal organ culture Comp Biochem Physiol A Comp Physiol 84 655 659
    • (1986) Comp Biochem Physiol A Comp Physiol , vol.84 , pp. 655-659
    • Carlier, H.1    Bernard, A.2    Hugon, J.S.3
  • 5
    • 34447500677 scopus 로고    scopus 로고
    • Regulation of triglyceride metabolism. III. Emerging role of lipid droplet protein ADFP in health and disease
    • BH Chang L Chan 2007 Regulation of triglyceride metabolism. III. Emerging role of lipid droplet protein ADFP in health and disease Am J Physiol Gastrointest Liver Physiol 292 G1465 G1468
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Chang, B.H.1    Chan, L.2
  • 6
    • 0014665068 scopus 로고
    • Quantitative densitometric thin-layer chromatography of lipids using copper acetate reagent
    • ME Fewster BJ Burns JF Mead 1969 Quantitative densitometric thin-layer chromatography of lipids using copper acetate reagent J Chromatogr 43 120 126
    • (1969) J Chromatogr , vol.43 , pp. 120-126
    • Fewster, M.E.1    Burns, B.J.2    Mead, J.F.3
  • 7
    • 0035809931 scopus 로고    scopus 로고
    • Caveolin-2 is targeted to lipid droplets, a new "membrane domain" in the cell
    • T Fujimoto H Kogo K Ishiguro K Tauchi R Nomura 2001 Caveolin-2 is targeted to lipid droplets, a new "membrane domain" in the cell J Cell Biol 152 1079 1085
    • (2001) J Cell Biol , vol.152 , pp. 1079-1085
    • Fujimoto, T.1    Kogo, H.2    Ishiguro, K.3    Tauchi, K.4    Nomura, R.5
  • 9
    • 42449097289 scopus 로고    scopus 로고
    • Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
    • A Guilherme JV Virbasius V Puri MP Czech 2008 Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes Nat Rev Mol Cell Biol 9 367 377
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 367-377
    • Guilherme, A.1    Virbasius, J.V.2    Puri, V.3    Czech, M.P.4
  • 10
    • 0034238090 scopus 로고    scopus 로고
    • 1H NMR visible lipids in the life and death of cells
    • JM Hakumaki RA Kauppinen 2000 1H NMR visible lipids in the life and death of cells Trends Biochem Sci 25 357 362
    • (2000) Trends Biochem Sci , vol.25 , pp. 357-362
    • Hakumaki, J.M.1    Kauppinen, R.A.2
  • 11
    • 0001506684 scopus 로고    scopus 로고
    • Cellular cholesterol regulates expression of the macrophage type B scavenger receptor, CD36
    • J Han DP Hajjar JM Tauras AC Nicholson 1999 Cellular cholesterol regulates expression of the macrophage type B scavenger receptor, CD36 J Lipid Res 40 830 838
    • (1999) J Lipid Res , vol.40 , pp. 830-838
    • Han, J.1    Hajjar, D.P.2    Tauras, J.M.3    Nicholson, A.C.4
  • 12
    • 0018128226 scopus 로고
    • Lipid extraction of tissues with a low-toxicity solvent
    • A Hara NS Radin 1978 Lipid extraction of tissues with a low-toxicity solvent Anal Biochem 90 420 426
    • (1978) Anal Biochem , vol.90 , pp. 420-426
    • Hara, A.1    Radin, N.S.2
  • 13
    • 3142527217 scopus 로고
    • A quantitative determination of the osmium tetroxide-lipoprotein interaction
    • TL Hayes FT Lindgren JW Gofman 1963 A quantitative determination of the osmium tetroxide-lipoprotein interaction J Cell Biol 19 251 255
    • (1963) J Cell Biol , vol.19 , pp. 251-255
    • Hayes, T.L.1    Lindgren, F.T.2    Gofman, J.W.3
  • 14
    • 0034990367 scopus 로고    scopus 로고
    • Evidence that newly synthesized esterified cholesterol is deposited in existing cytoplasmic lipid inclusions
    • G Kellner-Weibel B McHendry-Rinde MP Haynes S Adelman 2001 Evidence that newly synthesized esterified cholesterol is deposited in existing cytoplasmic lipid inclusions J Lipid Res 42 768 777
    • (2001) J Lipid Res , vol.42 , pp. 768-777
    • Kellner-Weibel, G.1    McHendry-Rinde, B.2    Haynes, M.P.3    Adelman, S.4
  • 16
    • 38849096602 scopus 로고    scopus 로고
    • Imaging of lipid biosynthesis: How a neutral lipid enters lipid droplets
    • L Kuerschner C Moessinger C Thiele 2008 Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets Traffic 9 338 352
    • (2008) Traffic , vol.9 , pp. 338-352
    • Kuerschner, L.1    Moessinger, C.2    Thiele, C.3
  • 17
    • 0030464976 scopus 로고    scopus 로고
    • Disruption of the vimentin intermediate filament system during adipose conversion of 3T3-L1 cells inhibits lipid droplet accumulation
    • JG Lieber RM Evans 1996 Disruption of the vimentin intermediate filament system during adipose conversion of 3T3-L1 cells inhibits lipid droplet accumulation J Cell Sci 109 3047 3058
    • (1996) J Cell Sci , vol.109 , pp. 3047-3058
    • Lieber, J.G.1    Evans, R.M.2
  • 18
    • 33744904687 scopus 로고    scopus 로고
    • The phosphorylation of serine 492 of perilipin a directs lipid droplet fragmentation and dispersion
    • A Marcinkiewicz D Gauthier A Garcia DL Brasaemle 2006 The phosphorylation of serine 492 of perilipin a directs lipid droplet fragmentation and dispersion J Biol Chem 281 11901 11909
    • (2006) J Biol Chem , vol.281 , pp. 11901-11909
    • Marcinkiewicz, A.1    Gauthier, D.2    Garcia, A.3    Brasaemle, D.L.4
  • 19
    • 33646168160 scopus 로고    scopus 로고
    • Lipid droplets: A unified view of a dynamic organelle
    • S Martin RG Parton 2006 Lipid droplets: a unified view of a dynamic organelle Nat Rev Mol Cell Biol 7 373 378
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 373-378
    • Martin, S.1    Parton, R.G.2
  • 20
    • 0020508521 scopus 로고
    • Morphological characterization of the cholesteryl ester cycle in cultured mouse macrophage foam cells
    • DJ McGookey RG Anderson 1983 Morphological characterization of the cholesteryl ester cycle in cultured mouse macrophage foam cells J Cell Biol 97 1156 1168
    • (1983) J Cell Biol , vol.97 , pp. 1156-1168
    • McGookey, D.J.1    Anderson, R.G.2
  • 21
    • 30044438117 scopus 로고    scopus 로고
    • Perilipin targets a novel pool of lipid droplets for lipolytic attack by hormone-sensitive lipase
    • HP Moore RB Silver EP Mottillo DA Bernlohr JG Granneman 2005 Perilipin targets a novel pool of lipid droplets for lipolytic attack by hormone-sensitive lipase J Biol Chem 280 43109 43120
    • (2005) J Biol Chem , vol.280 , pp. 43109-43120
    • Moore, H.P.1    Silver, R.B.2    Mottillo, E.P.3    Bernlohr, D.A.4    Granneman, J.G.5
  • 22
    • 0034903123 scopus 로고    scopus 로고
    • The biogenesis and functions of lipid bodies in animals, plants and microorganisms
    • DJ Murphy 2001 The biogenesis and functions of lipid bodies in animals, plants and microorganisms Prog Lipid Res 40 325 438
    • (2001) Prog Lipid Res , vol.40 , pp. 325-438
    • Murphy, D.J.1
  • 23
    • 0032911957 scopus 로고    scopus 로고
    • Mechanisms of lipid-body formation
    • DJ Murphy J Vance 1999 Mechanisms of lipid-body formation Trends Biochem Sci 24 109 115
    • (1999) Trends Biochem Sci , vol.24 , pp. 109-115
    • Murphy, D.J.1    Vance, J.2
  • 24
    • 12844263497 scopus 로고    scopus 로고
    • Triacylglycerol is synthesized in a specific subclass of caveolae in primary adipocytes
    • A Ost U Ortegren J Gustavsson FH Nystrom P Stralfors 2005 Triacylglycerol is synthesized in a specific subclass of caveolae in primary adipocytes J Biol Chem 280 5 8
    • (2005) J Biol Chem , vol.280 , pp. 5-8
    • Ost, A.1    Ortegren, U.2    Gustavsson, J.3    Nystrom, F.H.4    Stralfors, P.5
  • 25
    • 34547216748 scopus 로고    scopus 로고
    • A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum
    • HL Ploegh 2007 A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum Nature 448 435 438
    • (2007) Nature , vol.448 , pp. 435-438
    • Ploegh, H.L.1
  • 26
    • 52649114611 scopus 로고
    • The use of lead citrate at high pH as an electron-opaque stain in electron microscopy
    • ES Reynolds 1963 The use of lead citrate at high pH as an electron-opaque stain in electron microscopy J Cell Biol 17 208 212
    • (1963) J Cell Biol , vol.17 , pp. 208-212
    • Reynolds, E.S.1
  • 27
    • 33751161853 scopus 로고    scopus 로고
    • Adipophilin-enriched domains in the ER membrane are sites of lipid droplet biogenesis
    • H Robenek O Hofnagel I Buers MJ Robenek D Troyer NJ Severs 2006 Adipophilin-enriched domains in the ER membrane are sites of lipid droplet biogenesis J Cell Sci 119 4215 4224
    • (2006) J Cell Sci , vol.119 , pp. 4215-4224
    • Robenek, H.1    Hofnagel, O.2    Buers, I.3    Robenek, M.J.4    Troyer, D.5    Severs, N.J.6
  • 28
    • 64149132208 scopus 로고    scopus 로고
    • The endoplasmic reticulum enzyme DGAT2 is found in mitochondria- associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria
    • SJ Stone MC Levin P Zhou J Han TC Walther RV Farese Jr 2009 The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria J Biol Chem 284 5352 5361
    • (2009) J Biol Chem , vol.284 , pp. 5352-5361
    • Stone, S.J.1    Levin, M.C.2    Zhou, P.3    Han, J.4    Walther, T.C.5    Farese Jr, R.V.6
  • 29
    • 0037113954 scopus 로고    scopus 로고
    • The surface of lipid droplets is a phospholipid monolayer with a unique fatty acid composition
    • K Tauchi-Sato S Ozeki T Houjou R Taguchi T Fujimoto 2002 The surface of lipid droplets is a phospholipid monolayer with a unique fatty acid composition J Biol Chem 277 44507 44512
    • (2002) J Biol Chem , vol.277 , pp. 44507-44512
    • Tauchi-Sato, K.1    Ozeki, S.2    Houjou, T.3    Taguchi, R.4    Fujimoto, T.5
  • 30
  • 31
    • 18944391677 scopus 로고    scopus 로고
    • Neutral lipid bodies in prokaryotes: Recent insights into structure, formation, and relationship to eukaryotic lipid depots
    • M Waltermann A Steinbuchel 2005 Neutral lipid bodies in prokaryotes: recent insights into structure, formation, and relationship to eukaryotic lipid depots J Bacteriol 187 3607 3619
    • (2005) J Bacteriol , vol.187 , pp. 3607-3619
    • Waltermann, M.1    Steinbuchel, A.2
  • 32
    • 34548514866 scopus 로고    scopus 로고
    • Proteins under new management: Lipid droplets deliver
    • MA Welte 2007 Proteins under new management: lipid droplets deliver Trends Cell Biol 17 363 369
    • (2007) Trends Cell Biol , vol.17 , pp. 363-369
    • Welte, M.A.1
  • 34
    • 0018759949 scopus 로고
    • A chemical mechanism for tissue staining by osmium tetroxide-ferrocyanide mixtures
    • DL White JE Mazurkiewicz RJ Barrnett 1979 A chemical mechanism for tissue staining by osmium tetroxide-ferrocyanide mixtures J Histochem Cytochem 27 1084 1091
    • (1979) J Histochem Cytochem , vol.27 , pp. 1084-1091
    • White, D.L.1    Mazurkiewicz, J.E.2    Barrnett, R.J.3
  • 35
    • 34248189053 scopus 로고    scopus 로고
    • CGI-58 facilitates lipolysis on lipid droplets but is not involved in the vesiculation of lipid droplets caused by hormonal stimulation
    • T Yamaguchi N Omatsu E Morimoto H Nakashima K Ueno T Tanaka K Satouchi F Hirose T Osumi 2007 CGI-58 facilitates lipolysis on lipid droplets but is not involved in the vesiculation of lipid droplets caused by hormonal stimulation J Lipid Res 48 1078 1089
    • (2007) J Lipid Res , vol.48 , pp. 1078-1089
    • Yamaguchi, T.1    Omatsu, N.2    Morimoto, E.3    Nakashima, H.4    Ueno, K.5    Tanaka, T.6    Satouchi, K.7    Hirose, F.8    Osumi, T.9
  • 36
    • 58149457426 scopus 로고    scopus 로고
    • Thematic review series: Glycerolipids. DGAT enzymes and triacylglycerol biosynthesis
    • CL Yen SJ Stone S Koliwad C Harris RV Farese Jr 2008 Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis J Lipid Res 49 2283 2301
    • (2008) J Lipid Res , vol.49 , pp. 2283-2301
    • Yen, C.L.1    Stone, S.J.2    Koliwad, S.3    Harris, C.4    Farese Jr, R.V.5


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