Effects of citraconylation on enzymatic modification of human proinsulin using trypsin and carboxypeptidase B

Biotechnology Progress

Volumn 25, Issue 4, 2009, Pages 1064-1070

  Son, Young Jin ^a   Kim, Chang Kyu ^b   Kim, Young Bong ^b   Kweon, Dae Hyuk ^c   Park, Yong Cheol ^a   Seo, Jin Ho ^a  

^a Seoul National University   (South Korea)

^b Konkuk University   (South Korea)

^c Sungkyunkwan University   (South Korea)

Author keywords

Citraconylation; Des threonine insulin; Escherichia coli; Human insulin; Trypsin

Indexed keywords

BLOOD GLUCOSE LEVEL; CARBOXYPEPTIDASE; CITRACONIC ANHYDRIDES; CITRACONYLATION; CONVERSION YIELD; DES-THREONINE INSULIN; ENZYMATIC MODIFICATION; G PROTEIN; HUMAN BODIES; HUMAN INSULIN; HUMAN PROINSULIN; HYDROGEN PEROXIDE ADDITIONS; LYSINE RESIDUES; POLYPEPTIDE HORMONES; PRODUCTION YIELD; PROINSULIN; PURIFICATION PROCESS; REACTION SOLUTIONS; RECOMBINANT ESCHERICHIA COLI; SIMPLE METHOD; TRYPSIN;

AMINO ACIDS; CELL MEMBRANES; ENZYMATIC HYDROLYSIS; ESCHERICHIA COLI; GLUCOSE; HYDROGEN; HYDROGEN PEROXIDE;

INSULIN;

CARBOXYPEPTIDASE B; CITRACONIC ANHYDRIDE; PROINSULIN; TRYPSIN;

AMINO ACID SEQUENCE; CHEMISTRY; CONFERENCE PAPER; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN PROCESSING;

AMINO ACID SEQUENCE; CARBOXYPEPTIDASE B; CITRACONIC ANHYDRIDES; HUMANS; MOLECULAR SEQUENCE DATA; PROINSULIN; PROTEIN PROCESSING, POST-TRANSLATIONAL; TRYPSIN;

ESCHERICHIA COLI;

EID: 69149092236     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1002/btpr.195     Document Type: Conference Paper

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