-
1
-
-
1042298568
-
Platelets and anti-platelet therapy
-
McNicol A, Israels SJ. Platelets and anti-platelet therapy. J Pharmacol Sci 2003; 93: 381-96.
-
(2003)
J Pharmacol Sci
, vol.93
, pp. 381-396
-
-
McNicol, A.1
Israels, S.J.2
-
2
-
-
9144270451
-
Expert consensus document on the use of antiplatelet agents. The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European society of cardiology
-
Patrono C, Bachmann F, Baigent C, Bode C, De Caterina R, Charbonnier B, et al. Expert consensus document on the use of antiplatelet agents. The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European society of cardiology. Eur Heart J 2004; 25: 166-81.
-
(2004)
Eur Heart J
, vol.25
, pp. 166-181
-
-
Patrono, C.1
Bachmann, F.2
Baigent, C.3
Bode, C.4
De Caterina, R.5
Charbonnier, B.6
-
3
-
-
0028118792
-
Aspirin, platelets, and thrombosis: Theory and practice
-
Roth GJ, Calverley DC. Aspirin, platelets, and thrombosis: theory and practice. Blood 1994; 83: 885-98.
-
(1994)
Blood
, vol.83
, pp. 885-898
-
-
Roth, G.J.1
Calverley, D.C.2
-
5
-
-
85047693299
-
Central role of the P2Y12 receptor in platelet activation
-
Dorsam RT, Kunapuli SP. Central role of the P2Y12 receptor in platelet activation. J Clin Invest 2004; 113: 340-5.
-
(2004)
J Clin Invest
, vol.113
, pp. 340-345
-
-
Dorsam, R.T.1
Kunapuli, S.P.2
-
6
-
-
0038508970
-
The metabolism of clopidogrel is catalyzed by human cytochrome P450 3A and is inhibited by atorvastatin
-
Clarke TA, Waskell LA. The metabolism of clopidogrel is catalyzed by human cytochrome P450 3A and is inhibited by atorvastatin. Drug Metab Dispos 2003; 31: 53-9.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 53-59
-
-
Clarke, T.A.1
Waskell, L.A.2
-
7
-
-
18644372477
-
Structure and stereochemistry of the active metabolite of clopidogrel
-
Pereillo JM, Maftouh M, Andrieu A, Uzabiaga MF, Fedeli O, Savi P, et al. Structure and stereochemistry of the active metabolite of clopidogrel. Drug Metab Dispos 2002; 30: 1288-95.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1288-1295
-
-
Pereillo, J.M.1
Maftouh, M.2
Andrieu, A.3
Uzabiaga, M.F.4
Fedeli, O.5
Savi, P.6
-
8
-
-
0032814002
-
Clopidogrel loading dose regimens: Kinetic profile of pharmacodynamic response in healthy subjects
-
Savcic M, Hauert J, Bachmann F, Wyld PJ, Geudelin B, Cariou R. Clopidogrel loading dose regimens: kinetic profile of pharmacodynamic response in healthy subjects. Semin Thromb Hemost 1999; 25 Suppl 2: 15-9.
-
(1999)
Semin Thromb Hemost
, vol.25
, Issue.SUPPL. 2
, pp. 15-19
-
-
Savcic, M.1
Hauert, J.2
Bachmann, F.3
Wyld, P.J.4
Geudelin, B.5
Cariou, R.6
-
9
-
-
0026050491
-
Effects of ticlopidine on erythrocyte aggregation in thrombotic disorders
-
Hayakawa M, Kuzuya F. Effects of ticlopidine on erythrocyte aggregation in thrombotic disorders. Angiology 1991; 42: 747-53.
-
(1991)
Angiology
, vol.42
, pp. 747-753
-
-
Hayakawa, M.1
Kuzuya, F.2
-
11
-
-
18044378766
-
Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis
-
Savi P, Herbert JM. Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin Thromb Hemost 2005; 31: 174-83.
-
(2005)
Semin Thromb Hemost
, vol.31
, pp. 174-183
-
-
Savi, P.1
Herbert, J.M.2
-
12
-
-
23644444919
-
A randomized trial comparing clopidogrel versus ticlopidine therapy in patients undergoing infarct artery stenting for acute myocardial infarction with abciximab as adjunctive therapy
-
Parodi G, Sciagra R, Migliorini A, Memisha G, Moschi G, Valenti R, et al. A randomized trial comparing clopidogrel versus ticlopidine therapy in patients undergoing infarct artery stenting for acute myocardial infarction with abciximab as adjunctive therapy. Am Heart J 2005; 150: 220.
-
(2005)
Am Heart J
, vol.150
, pp. 220
-
-
Parodi, G.1
Sciagra, R.2
Migliorini, A.3
Memisha, G.4
Moschi, G.5
Valenti, R.6
-
14
-
-
20144373281
-
Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation
-
Sabatine MS, Cannon CP, Gibson CM, Lopez-Sendon JL, Montalescot G, Theroux P, et al. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. N Engl J Med 2005; 352: 1179-89.
-
(2005)
N Engl J Med
, vol.352
, pp. 1179-1189
-
-
Sabatine, M.S.1
Cannon, C.P.2
Gibson, C.M.3
Lopez-Sendon, J.L.4
Montalescot, G.5
Theroux, P.6
-
15
-
-
24644495673
-
Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: The PCI-CLARITY study
-
Sabatine MS, Cannon CP, Gibson CM, Lopez-Sendon JL, Montalescot G, Theroux P, et al. Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: the PCI-CLARITY study. JAMA 2005; 294: 1224-32.
-
(2005)
JAMA
, vol.294
, pp. 1224-1232
-
-
Sabatine, M.S.1
Cannon, C.P.2
Gibson, C.M.3
Lopez-Sendon, J.L.4
Montalescot, G.5
Theroux, P.6
-
16
-
-
27644548513
-
COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial) collaborative group. Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: Randomized placebo-controlled trial
-
Chen ZM, Jiang LX, Chen YP, Xie JX, Pan HC, Peto R, et al. COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial) collaborative group. Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomized placebo-controlled trial. Lancet 2005; 366: 1607-21.
-
(2005)
Lancet
, vol.366
, pp. 1607-1621
-
-
Chen, Z.M.1
Jiang, L.X.2
Chen, Y.P.3
Xie, J.X.4
Pan, H.C.5
Peto, R.6
-
17
-
-
20144373281
-
CLARITY-TIMI 28 Investigators. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation
-
Sabatine MS, Cannon CP, Gibson CM, Lopez-Sendon JL, Montalescot G, Theroux P, et al; CLARITY-TIMI 28 Investigators. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. N Engl J Med 2005; 352: 1179-89.
-
(2005)
N Engl J Med
, vol.352
, pp. 1179-1189
-
-
Sabatine, M.S.1
Cannon, C.P.2
Gibson, C.M.3
Lopez-Sendon, J.L.4
Montalescot, G.5
Theroux, P.6
-
18
-
-
33644886913
-
Aspirin and clopidogrel resistance: An emerging clinical entity
-
Wang TH, Bhatt DL, Topol EJ. Aspirin and clopidogrel resistance: an emerging clinical entity. Eur Heart J 2006; 27: 647-54.
-
(2006)
Eur Heart J
, vol.27
, pp. 647-654
-
-
Wang, T.H.1
Bhatt, D.L.2
Topol, E.J.3
-
19
-
-
34247890094
-
Significance of aspirin and clopidogrel resistance in patients undergoing percutaneous coronary interventions
-
Pregowski J, Witkowski A, Sitkiewicz D. Significance of aspirin and clopidogrel resistance in patients undergoing percutaneous coronary interventions. Curr Vasc Pharmacol 2007; 5: 135-40.
-
(2007)
Curr Vasc Pharmacol
, vol.5
, pp. 135-140
-
-
Pregowski, J.1
Witkowski, A.2
Sitkiewicz, D.3
-
20
-
-
0031837219
-
Assessment of platelet function assays
-
Nicholson NS, Panzer-Knodle SG, Haas NF, Taite BB, Szalony JA, Page JD, et al. Assessment of platelet function assays. Am Heart J 1998; 135: 170-8.
-
(1998)
Am Heart J
, vol.135
, pp. 170-178
-
-
Nicholson, N.S.1
Panzer-Knodle, S.G.2
Haas, N.F.3
Taite, B.B.4
Szalony, J.A.5
Page, J.D.6
-
21
-
-
8344231455
-
Aspirin and clopidogrel: Efficacy, safety, and the issue of drug resistance
-
Cattaneo M. Aspirin and clopidogrel: efficacy, safety, and the issue of drug resistance. Arterioscler Thromb Vasc Biol 2004; 24: 1980-7.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1980-1987
-
-
Cattaneo, M.1
-
22
-
-
0028146120
-
Phosphorylation of focal adhesion vasodilator-stimulated phosphoprotein at Ser157 in intact human platelets correlates with fibrinogen receptor inhibition
-
Horstrup K, Jablonka B, Hönig-Liedl P, Just M, Kochsiek K, Walter U. Phosphorylation of focal adhesion vasodilator-stimulated phosphoprotein at Ser157 in intact human platelets correlates with fibrinogen receptor inhibition. Eur J Biochem 1994: 225; 21-7.
-
(1994)
Eur J Biochem
, vol.225
, pp. 21-27
-
-
Horstrup, K.1
Jablonka, B.2
Hönig-Liedl, P.3
Just, M.4
Kochsiek, K.5
Walter, U.6
-
23
-
-
0038354521
-
Resistance to thienopyridines: Clinical detection of coronary stent thrombosis by monitoring of vasodilator-stimulated phosphoprotein phosphorylation
-
Barragan P, Bouvier JL, Roquebert PO, Macaluso G, Commeau P, Comet B, et al. Resistance to thienopyridines: clinical detection of coronary stent thrombosis by monitoring of vasodilator-stimulated phosphoprotein phosphorylation. Catheter Cardiovasc Interv 2003; 59: 295-302.
-
(2003)
Catheter Cardiovasc Interv
, vol.59
, pp. 295-302
-
-
Barragan, P.1
Bouvier, J.L.2
Roquebert, P.O.3
Macaluso, G.4
Commeau, P.5
Comet, B.6
-
24
-
-
41249093357
-
Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: A multicenter randomized prospective study
-
Bonello L, Camoin-Jau L, Arques S, Boyer C, Panagides D, Wittenberg O, et al. Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: a multicenter randomized prospective study. J Am Coll Cardiol 2008; 51: 1404-11.
-
(2008)
J Am Coll Cardiol
, vol.51
, pp. 1404-1411
-
-
Bonello, L.1
Camoin-Jau, L.2
Arques, S.3
Boyer, C.4
Panagides, D.5
Wittenberg, O.6
-
25
-
-
10444235983
-
Clopidogrel resistance: A new chapter in a fast-moving story
-
Wiviott SD, Antman EM. Clopidogrel resistance: a new chapter in a fast-moving story. Circulation 2004; 109: 3064-7.
-
(2004)
Circulation
, vol.109
, pp. 3064-3067
-
-
Wiviott, S.D.1
Antman, E.M.2
-
26
-
-
33947328091
-
-
Siller-Matula J, Schrör K, Wojta J, Huber K. Thienopyridines in cardiovascular disease: focus on clopidogrel resistance. Thromb Haemost 2007; 97: 385-93.
-
Siller-Matula J, Schrör K, Wojta J, Huber K. Thienopyridines in cardiovascular disease: focus on clopidogrel resistance. Thromb Haemost 2007; 97: 385-93.
-
-
-
-
27
-
-
33645967456
-
Variable therapeutic effectiveness of clopidogrel in acute coronary syndromes
-
Heptinstall S. Variable therapeutic effectiveness of clopidogrel in acute coronary syndromes. J Thromb Haemost 2006; 4: 539-41.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 539-541
-
-
Heptinstall, S.1
-
28
-
-
4944261759
-
Loading with 600 mg clopidogrel in patients with coronary artery disease with and without chronic clopidogrel therapy
-
Kastrati A, von Beckerath N, Joost A, Pogatsa-Murray G, Gorchakova O, Schomig A. Loading with 600 mg clopidogrel in patients with coronary artery disease with and without chronic clopidogrel therapy. Circulation 2004; 110: 1916-9.
-
(2004)
Circulation
, vol.110
, pp. 1916-1919
-
-
Kastrati, A.1
von Beckerath, N.2
Joost, A.3
Pogatsa-Murray, G.4
Gorchakova, O.5
Schomig, A.6
-
29
-
-
19644372173
-
Time dependence of platelet inhibition after a 600-mg loading dose of clopidogrel in a large, unselected cohort of candidates for percutaneous coronary intervention
-
Hochholzer W, Trenk D, Frundi D, Blanke P, Fischer B, Andris K, et al. Time dependence of platelet inhibition after a 600-mg loading dose of clopidogrel in a large, unselected cohort of candidates for percutaneous coronary intervention. Circulation 2005; 111: 2560-4.
-
(2005)
Circulation
, vol.111
, pp. 2560-2564
-
-
Hochholzer, W.1
Trenk, D.2
Frundi, D.3
Blanke, P.4
Fischer, B.5
Andris, K.6
-
30
-
-
17744376570
-
Randomized trial of high loading dose of clopidogrel for reduction of periprocedural myocardial infarction in patients undergoing coronary intervention: Results from the ARMYDA-2 (Antiplatelet therapy for Reduction of MYocardial Damage during Angioplasty) study
-
Patti G, Colonna G, Pasceri V, Pepe LL, Montinaro A, Di Sciascio G. Randomized trial of high loading dose of clopidogrel for reduction of periprocedural myocardial infarction in patients undergoing coronary intervention: results from the ARMYDA-2 (Antiplatelet therapy for Reduction of MYocardial Damage during Angioplasty) study. Circulation 2005; 111: 2099-106.
-
(2005)
Circulation
, vol.111
, pp. 2099-2106
-
-
Patti, G.1
Colonna, G.2
Pasceri, V.3
Pepe, L.L.4
Montinaro, A.5
Di Sciascio, G.6
-
31
-
-
33747874088
-
ALBION Trial Investigators. A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: The ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial
-
Montalescot G, Sideris G, Meuleman C, Bal-dit-Sollier C, Lellouche N, Steg PG, et al. ALBION Trial Investigators. A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: the ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial. J Am Coll Cardiol 2006; 48: 931-8.
-
(2006)
J Am Coll Cardiol
, vol.48
, pp. 931-938
-
-
Montalescot, G.1
Sideris, G.2
Meuleman, C.3
Bal-dit-Sollier, C.4
Lellouche, N.5
Steg, P.G.6
-
32
-
-
27744516843
-
Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg loading doses of clopidogrel: Results of the ISAR-CHOICE (Intracoronary Stenting and Antithrombotic Regimen: Choose Between 3 High Oral Doses for Immediate Clopidogrel Effect) Trial
-
von Beckerath N, Taubert D, Pogatsa-Murray G, Schomig E, Kastrati A, Schomig A. Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg loading doses of clopidogrel: results of the ISAR-CHOICE (Intracoronary Stenting and Antithrombotic Regimen: Choose Between 3 High Oral Doses for Immediate Clopidogrel Effect) Trial. Circulation 2005; 112: 2946-50.
-
(2005)
Circulation
, vol.112
, pp. 2946-2950
-
-
von Beckerath, N.1
Taubert, D.2
Pogatsa-Murray, G.3
Schomig, E.4
Kastrati, A.5
Schomig, A.6
-
33
-
-
0030004755
-
In vitro comparative inhibition profiles of major human drug metabolising cytochrome P450 isozymes (CYP2C9, CYP2D6 and CYP3A4) by HMG-CoA reductase inhibitors
-
Transon C, Leemann T, Dayer P. In vitro comparative inhibition profiles of major human drug metabolising cytochrome P450 isozymes (CYP2C9, CYP2D6 and CYP3A4) by HMG-CoA reductase inhibitors. Eur J Clin Pharmacol 1996; 50: 209-15.
-
(1996)
Eur J Clin Pharmacol
, vol.50
, pp. 209-215
-
-
Transon, C.1
Leemann, T.2
Dayer, P.3
-
34
-
-
0036291921
-
Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors
-
Williams D, Feely J. Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors. Clin Pharmacokinet 2002; 41: 343-70.
-
(2002)
Clin Pharmacokinet
, vol.41
, pp. 343-370
-
-
Williams, D.1
Feely, J.2
-
35
-
-
0033783036
-
Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin
-
Jacobsen W, Kuhn B, Soldner A, Kirchner G, Sewing KF, Kollman PA, et al. Lactonization is the critical first step in the disposition of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor atorvastatin. Drug Metab Dispos 2000; 28: 1369-78.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 1369-1378
-
-
Jacobsen, W.1
Kuhn, B.2
Soldner, A.3
Kirchner, G.4
Sewing, K.F.5
Kollman, P.A.6
-
36
-
-
0037422534
-
Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: A new drug-drug interaction
-
Lau WC, Waskell LA, Watkins PB, Neer CJ, Horowitz K, Hopp AS, et al. Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: a new drug-drug interaction. Circulation 2003; 107: 32-7.
-
(2003)
Circulation
, vol.107
, pp. 32-37
-
-
Lau, W.C.1
Waskell, L.A.2
Watkins, P.B.3
Neer, C.J.4
Horowitz, K.5
Hopp, A.S.6
-
37
-
-
0242298647
-
Effects of statins on platelet inhibition by a high loading dose of clopidogrel
-
Muller I, Besta F, Schulz C, Li Z, Massberg S, Gawaz M. Effects of statins on platelet inhibition by a high loading dose of clopidogrel. Circulation 2003; 108: 2195-7.
-
(2003)
Circulation
, vol.108
, pp. 2195-2197
-
-
Muller, I.1
Besta, F.2
Schulz, C.3
Li, Z.4
Massberg, S.5
Gawaz, M.6
-
38
-
-
1642410985
-
Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes
-
Mitsios JV, Papathanasiou AI, Rodis FI, Elisaf M, Goudevenos JA, Tselepis AD. Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes. Circulation 2004; 109: 1335-8.
-
(2004)
Circulation
, vol.109
, pp. 1335-1338
-
-
Mitsios, J.V.1
Papathanasiou, A.I.2
Rodis, F.I.3
Elisaf, M.4
Goudevenos, J.A.5
Tselepis, A.D.6
-
39
-
-
6344226832
-
Absence of interaction between atorvastatin or other statins and clopidogrel: Results from the interaction study
-
Serebruany VL, Midei MG, Malinin AI, Oshrine BR, Lowry DR, Sane DC, et al. Absence of interaction between atorvastatin or other statins and clopidogrel: results from the interaction study. Arch Intern Med 2004; 164: 2051-7.
-
(2004)
Arch Intern Med
, vol.164
, pp. 2051-2057
-
-
Serebruany, V.L.1
Midei, M.G.2
Malinin, A.I.3
Oshrine, B.R.4
Lowry, D.R.5
Sane, D.C.6
-
40
-
-
7544244139
-
Antiplatelet effects of a 600 mg loading dose of clopidogrel are not attenuated in patients receiving atorvastatin or simvastatin for at least 4 weeks prior to coronary artery stenting
-
Gorchakova O, von Beckerath N, Gawaz M, Mocz A, Joost A, Schomig A, et al. Antiplatelet effects of a 600 mg loading dose of clopidogrel are not attenuated in patients receiving atorvastatin or simvastatin for at least 4 weeks prior to coronary artery stenting. Eur Heart J 2004; 25: 1898-902.
-
(2004)
Eur Heart J
, vol.25
, pp. 1898-1902
-
-
Gorchakova, O.1
von Beckerath, N.2
Gawaz, M.3
Mocz, A.4
Joost, A.5
Schomig, A.6
-
41
-
-
34447312473
-
CHARISMA Investigators. Lack of Evidence of a Clopidogrel and Statin Interaction in the CHARISMA Trial
-
Saw J, Brennan DM, Steinhubl SR, Bhatt DL, Mak KH, Fox K, et al; CHARISMA Investigators. Lack of Evidence of a Clopidogrel and Statin Interaction in the CHARISMA Trial. J Am Coll Cardiol 2007; 50: 291-5.
-
(2007)
J Am Coll Cardiol
, vol.50
, pp. 291-295
-
-
Saw, J.1
Brennan, D.M.2
Steinhubl, S.R.3
Bhatt, D.L.4
Mak, K.H.5
Fox, K.6
-
42
-
-
38349065084
-
Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: The randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study
-
Gilard M, Arnaud B, Cornily JC, Le Gal G, Lacut K, Le Calvez G, et al. Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study. J Am Coll Cardiol 2008; 51: 256-60.
-
(2008)
J Am Coll Cardiol
, vol.51
, pp. 256-260
-
-
Gilard, M.1
Arnaud, B.2
Cornily, J.C.3
Le Gal, G.4
Lacut, K.5
Le Calvez, G.6
-
43
-
-
64849087438
-
Impact of proton pump inhibitors on the antiplatelet effects of clopidogrel
-
Sibbing D, Morath T, Stegherr J, Braun S, Vogt W, Hadamitzky M, et al. Impact of proton pump inhibitors on the antiplatelet effects of clopidogrel. Thromb Haemost 2009; 101: 714-9.
-
(2009)
Thromb Haemost
, vol.101
, pp. 714-719
-
-
Sibbing, D.1
Morath, T.2
Stegherr, J.3
Braun, S.4
Vogt, W.5
Hadamitzky, M.6
-
44
-
-
54349121974
-
Calcium-channel blockers reduce the antiplatelet effect of clopidogrel
-
Siller-Matula JM, Lang I, Christ G, Jilma B. Calcium-channel blockers reduce the antiplatelet effect of clopidogrel. J Am Coll Cardiol 2008; 52: 1557-63.
-
(2008)
J Am Coll Cardiol
, vol.52
, pp. 1557-1563
-
-
Siller-Matula, J.M.1
Lang, I.2
Christ, G.3
Jilma, B.4
-
45
-
-
33746792912
-
Contribution of gene sequence variations of the hepatic cytochrome P450 3A4 enzyme to variability in individual responsiveness to clopidogrel
-
Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, Ramirez C, Cavallari U, Trabetti E, et al. Contribution of gene sequence variations of the hepatic cytochrome P450 3A4 enzyme to variability in individual responsiveness to clopidogrel. Arterioscler Thromb Vasc Biol 2006; 26: 1895-900.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 1895-1900
-
-
Angiolillo, D.J.1
Fernandez-Ortiz, A.2
Bernardo, E.3
Ramirez, C.4
Cavallari, U.5
Trabetti, E.6
-
46
-
-
58249135635
-
Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: A cohort study
-
Collet JP, Hulot JS, Pena A, Villard E, Esteve JB, Silvain J, et al. Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study. Lancet 2009; 373: 309-17.
-
(2009)
Lancet
, vol.373
, pp. 309-317
-
-
Collet, J.P.1
Hulot, J.S.2
Pena, A.3
Villard, E.4
Esteve, J.B.5
Silvain, J.6
-
47
-
-
58749094444
-
Cytochrome p-450 polymorphisms and response to clopidogrel
-
Mega JL, Close SL, Wiviott SD, Shen L, Hockett RD, Brandt JT, et al. Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl J Med 2009; 360: 354-62.
-
(2009)
N Engl J Med
, vol.360
, pp. 354-362
-
-
Mega, J.L.1
Close, S.L.2
Wiviott, S.D.3
Shen, L.4
Hockett, R.D.5
Brandt, J.T.6
-
48
-
-
1642453779
-
Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance
-
Lau WC, Gurbel PA, Watkins PB, Neer CJ, Hopp AS, Carville DG, et al. Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance. Circulation 2004; 109: 166-71.
-
(2004)
Circulation
, vol.109
, pp. 166-171
-
-
Lau, W.C.1
Gurbel, P.A.2
Watkins, P.B.3
Neer, C.J.4
Hopp, A.S.5
Carville, D.G.6
-
49
-
-
0038291914
-
Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement
-
Muller I, Besta F, Schulz C, Massberg S, Schonig A, Gawaz M. Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement. Thromb Haemost 2003; 89: 783-7.
-
(2003)
Thromb Haemost
, vol.89
, pp. 783-787
-
-
Muller, I.1
Besta, F.2
Schulz, C.3
Massberg, S.4
Schonig, A.5
Gawaz, M.6
-
50
-
-
20344408497
-
Stent thrombosis is associated with an impaired response to antiplatelet therapy
-
Wenaweser P, Dorffler-Melly J, Imboden K, Windecker S, Togni M, Meier B et al. Stent thrombosis is associated with an impaired response to antiplatelet therapy. J Am Coll Cardiol 2005; 45: 1748-52.
-
(2005)
J Am Coll Cardiol
, vol.45
, pp. 1748-1752
-
-
Wenaweser, P.1
Dorffler-Melly, J.2
Imboden, K.3
Windecker, S.4
Togni, M.5
Meier, B.6
-
51
-
-
9644281093
-
The difference between clopidogrel responsiveness and posttreatment platelet reactivity
-
Samara WM, Bliden KP, Tantry US, Gurbel PA. The difference between clopidogrel responsiveness and posttreatment platelet reactivity. Thromb Res 2005; 115: 89-94.
-
(2005)
Thromb Res
, vol.115
, pp. 89-94
-
-
Samara, W.M.1
Bliden, K.P.2
Tantry, U.S.3
Gurbel, P.A.4
-
52
-
-
8344221349
-
Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction
-
Matetzky S, Shenkman B, Guetta V, Shechter M, Bienart R, Goldenberg I, et al. Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction. Circulation 2004; 109: 3171-5.
-
(2004)
Circulation
, vol.109
, pp. 3171-3175
-
-
Matetzky, S.1
Shenkman, B.2
Guetta, V.3
Shechter, M.4
Bienart, R.5
Goldenberg, I.6
-
53
-
-
18144371221
-
The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting
-
Gurbel PA, Bliden KP, Hayes KM, Yoho JA, Herzog WR, Tantry US. The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting. J Am Coll Cardiol 2005; 45: 1392-6.
-
(2005)
J Am Coll Cardiol
, vol.45
, pp. 1392-1396
-
-
Gurbel, P.A.1
Bliden, K.P.2
Hayes, K.M.3
Yoho, J.A.4
Herzog, W.R.5
Tantry, U.S.6
-
54
-
-
29344466941
-
Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: The role of dual drug resistance
-
Lev EI, Patel RT, Maresh KJ, Guthikonda S, Granada J, DeLao T, et al. Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: the role of dual drug resistance. J Am Coll Cardiol 2006; 47: 27-33.
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 27-33
-
-
Lev, E.I.1
Patel, R.T.2
Maresh, K.J.3
Guthikonda, S.4
Granada, J.5
DeLao, T.6
-
55
-
-
49349114160
-
Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents
-
Gori AM, Marcucci R, Migliorini A, Valenti R, Moschi G, Paniccia R, et al. Incidence and clinical impact of dual nonresponsiveness to aspirin and clopidogrel in patients with drug-eluting stents. J Am Coll Cardiol 2008; 52: 734-9.
-
(2008)
J Am Coll Cardiol
, vol.52
, pp. 734-739
-
-
Gori, A.M.1
Marcucci, R.2
Migliorini, A.3
Valenti, R.4
Moschi, G.5
Paniccia, R.6
-
56
-
-
33645052218
-
ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update the 2001)
-
Smith SC Jr, Feldman TE, Hirshfeld JW Jr, Jacobs AK, Kern MJ, King SB III et al. ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update the 2001). Circulation 2006; 113: e166-286.
-
(2006)
Circulation
, vol.113
-
-
Smith Jr, S.C.1
Feldman, T.E.2
Hirshfeld Jr, J.W.3
Jacobs, A.K.4
Kern, M.J.5
King III, S.B.6
-
57
-
-
0035085132
-
Open multicentre study of the P2T receptor antagonist AR-C69931MX assessing safety, tolerability and activity in patients with acute coronary syndromes
-
Storey RF, Oldroyd KG, Wilcox RG. Open multicentre study of the P2T receptor antagonist AR-C69931MX assessing safety, tolerability and activity in patients with acute coronary syndromes. Thromb Haemost 2001; 85: 401-7.
-
(2001)
Thromb Haemost
, vol.85
, pp. 401-407
-
-
Storey, R.F.1
Oldroyd, K.G.2
Wilcox, R.G.3
-
58
-
-
33646261670
-
Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: A double-blind comparison to clopidogrel with aspirin
-
Husted S, Emanuelsson H, Heptinstall S, Sandset PM, Wickens M, Peters G. Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: a double-blind comparison to clopidogrel with aspirin. Eur Heart J 2006; 27: 1038-47.
-
(2006)
Eur Heart J
, vol.27
, pp. 1038-1047
-
-
Husted, S.1
Emanuelsson, H.2
Heptinstall, S.3
Sandset, P.M.4
Wickens, M.5
Peters, G.6
-
59
-
-
27844463244
-
Cilostazol for Restenosis Trial (CREST) Investigators. Coronary stent restenosis in patients treated with cilostazol
-
Douglas JS Jr, Holmes DR Jr, Kereiakes DJ, Grines CL, Block E, Ghazzal ZM, et al; Cilostazol for Restenosis Trial (CREST) Investigators. Coronary stent restenosis in patients treated with cilostazol. Circulation 2005; 112: 2826-32.
-
(2005)
Circulation
, vol.112
, pp. 2826-2832
-
-
Douglas Jr, J.S.1
Holmes Jr, D.R.2
Kereiakes, D.J.3
Grines, C.L.4
Block, E.5
Ghazzal, Z.M.6
-
60
-
-
62549101321
-
Randomized comparison of adjunctive cilostazol versus high maintenance dose clopidogrel in patients with high post-treatment platelet reactivity: Results of the ACCEL-RESISTANCE (Adjunctive Cilostazol Versus High Maintenance Dose Clopidogrel in Patients With Clopidogrel Resistance) randomized study
-
Jeong YH, Lee SW, Choi BR, Kim IS, Seo MK, Kwak CH, et al. Randomized comparison of adjunctive cilostazol versus high maintenance dose clopidogrel in patients with high post-treatment platelet reactivity: results of the ACCEL-RESISTANCE (Adjunctive Cilostazol Versus High Maintenance Dose Clopidogrel in Patients With Clopidogrel Resistance) randomized study. J Am Coll Cardiol 2009; 53: 1101-9.
-
(2009)
J Am Coll Cardiol
, vol.53
, pp. 1101-1109
-
-
Jeong, Y.H.1
Lee, S.W.2
Choi, B.R.3
Kim, I.S.4
Seo, M.K.5
Kwak, C.H.6
-
61
-
-
0034068625
-
The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist properties
-
Sugidachi A, Asai F, Ogawa T, Inoue T, Koike H. The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist properties. Br J Pharmacol 2000; 129: 1439-46.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 1439-1446
-
-
Sugidachi, A.1
Asai, F.2
Ogawa, T.3
Inoue, T.4
Koike, H.5
-
62
-
-
21644448736
-
JUMBO-TIMI 26 Investigators. Randomized comparison of prasugrel (CS-747, LY640315), a novel thienopyridine P2Y12 antagonist, with clopidogrel in percutaneous coronary intervention: Results of the Joint Utilization of Medications to Block Platelets Optimally (JUMBO)-TIMI 26 trial
-
Wiviott SD, Antman EM, Winters KJ, Weerakkody G, Murphy SA, Behounek BD, et al; JUMBO-TIMI 26 Investigators. Randomized comparison of prasugrel (CS-747, LY640315), a novel thienopyridine P2Y12 antagonist, with clopidogrel in percutaneous coronary intervention: results of the Joint Utilization of Medications to Block Platelets Optimally (JUMBO)-TIMI 26 trial. Circulation 2005; 111: 3366-73.
-
(2005)
Circulation
, vol.111
, pp. 3366-3373
-
-
Wiviott, S.D.1
Antman, E.M.2
Winters, K.J.3
Weerakkody, G.4
Murphy, S.A.5
Behounek, B.D.6
-
63
-
-
36148983750
-
TRITON-TIMI 38 Investigators. Prasugrel vs clopigogrel in patients with acute coronary syndromes
-
Wiviott SD, Braunwald E, McCabe CH, Montalescot G, Ruzyllo W, Gottlieb S, et al; TRITON-TIMI 38 Investigators. Prasugrel vs clopigogrel in patients with acute coronary syndromes. N Eng J Med 2007; 357: 2001-15.
-
(2007)
N Eng J Med
, vol.357
, pp. 2001-2015
-
-
Wiviott, S.D.1
Braunwald, E.2
McCabe, C.H.3
Montalescot, G.4
Ruzyllo, W.5
Gottlieb, S.6
-
64
-
-
42149119040
-
TRITON-TIMI 38 Investigators. Intensive oral antiplatelet therapy for reduction of ischemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: A subanalysis of a randomized trial
-
Wiviott SD, Braunwald E, McCabe CH, Horvath I, Keltai M, Herrman JP, et al; TRITON-TIMI 38 Investigators. Intensive oral antiplatelet therapy for reduction of ischemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: a subanalysis of a randomized trial. Lancet 2008; 371: 1353-63.
-
(2008)
Lancet
, vol.371
, pp. 1353-1363
-
-
Wiviott, S.D.1
Braunwald, E.2
McCabe, C.H.3
Horvath, I.4
Keltai, M.5
Herrman, J.P.6
-
65
-
-
37849002889
-
Prasugrel achieves greater and faster P2Y12 receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease
-
Wallentin L, Varenhorst C, James S, Erlinge D, Braun OO, Jakubowski JA, et al. Prasugrel achieves greater and faster P2Y12 receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease. Eur Heart J 2008; 29: 21-30.
-
(2008)
Eur Heart J
, vol.29
, pp. 21-30
-
-
Wallentin, L.1
Varenhorst, C.2
James, S.3
Erlinge, D.4
Braun, O.O.5
Jakubowski, J.A.6
-
66
-
-
44949173754
-
Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation
-
Price MJ, Endemann S, Gollapudi RR, Valencia R, Stinis CT, Levisay JP, et al. Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation. Eur Heart J 2008; 29: 992-1000.
-
(2008)
Eur Heart J
, vol.29
, pp. 992-1000
-
-
Price, M.J.1
Endemann, S.2
Gollapudi, R.R.3
Valencia, R.4
Stinis, C.T.5
Levisay, J.P.6
-
67
-
-
67649654260
-
Antiplatelet drug 'resistance'. Part 1: Mechanisms and clinical measurements
-
Sweeny JM, Gorog DA, Fuster V. Antiplatelet drug 'resistance'. Part 1: mechanisms and clinical measurements. Nat Rev Cardiol 2009; 6: 273-82.
-
(2009)
Nat Rev Cardiol
, vol.6
, pp. 273-282
-
-
Sweeny, J.M.1
Gorog, D.A.2
Fuster, V.3
|