Addressing the malaria drug resistance challenge using flow cytometry to discover new antimalarials

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 18, 2009, Pages 5452-5457

  Grimberg, Brian T ^a   Jaworska, Maria M ^b   Hough, Lindsay B ^c   Zimmerman, Peter A ^a   Phillips, James G ^b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Curragh Chemistries Inc   (United States)

^c ALBANY MEDICAL COLLEGE   (United States)

Author keywords

Cytometry; Drug discovery; Malarial

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISININ; CHLOROQUINE; DNA; ETRAVIRINE; IMIDAZOLE DERIVATIVE; MEFLOQUINE; N (3 CHLOROPHENYL) 3 [3,5 DIMETHYL 4 (4 METHYL 1 PIPERAZINYLCARBONYL) 1H PYRROL 2 YLMETHYLENE] 2,3 DIHYDRO N METHYL 2 OXO 1H INDOLE 5 SULFONAMIDE; RILPIVIRINE; RNA; SORAFENIB;

ANTIMALARIAL ACTIVITY; ARTICLE; DRUG POTENCY; DRUG SCREENING; FLOW CYTOMETRY; IC 50; IN VITRO STUDY; MALARIA; NONHUMAN; PILOT STUDY; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIMALARIALS; DNA, PROTOZOAN; DRUG DISCOVERY; DRUG RESISTANCE; ERYTHROCYTES; FLOW CYTOMETRY; MALARIA, FALCIPARUM; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; RNA, PROTOZOAN; STRUCTURE-ACTIVITY RELATIONSHIP;

PLASMODIUM FALCIPARUM;

EID: 69049084901     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.07.095     Document Type: Article

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