Test-retest variability of high resolution positron emission tomography (PET) imaging of cortical serotonin (5HT2A) receptors in older, healthy adults

BMC Medical Imaging

Volumn 9, Issue , 2009, Pages

  Chow, Tiffany W ^a,b,c   Mamo, David C ^c,d   Uchida, Hiroyuki ^c,d   Graff Guerrero, Ariel ^c,d   Houle, Sylvain ^c,d   Smith, Gwenn S ^a,c,d   Pollock, Bruce G ^c,d   Mulsant, Benoit H ^c,d  

^a ROTMAN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

SEROTONIN 2A RECEPTOR; SETOPERONE; DIAGNOSTIC AGENT; PYRIMIDINONE DERIVATIVE; RADIOPHARMACEUTICAL AGENT; SEROTONIN 5 RECEPTOR; SEROTONIN RECEPTOR;

ADULT; AGED; ARTICLE; BILIRUBIN BINDING; BRAIN REGION; CINGULATE GYRUS; CORRELATION COEFFICIENT; FRONTAL LOBE; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; HUMAN EXPERIMENT; IMAGE ANALYSIS; INSULA; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; RIGHT HANDEDNESS; TEMPORAL LOBE; TEST RETEST RELIABILITY; BRAIN; FEMALE; IMAGE ENHANCEMENT; MALE; METABOLISM; METHODOLOGY; REFERENCE VALUE; REPRODUCIBILITY; SCINTISCANNING; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION;

AGED; BRAIN; FEMALE; HUMANS; IMAGE ENHANCEMENT; MALE; POSITRON-EMISSION TOMOGRAPHY; PYRIMIDINONES; RADIOPHARMACEUTICALS; RECEPTORS, SEROTONIN; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION;

EID: 68949211240     PISSN: None     EISSN: 14712342     Source Type: Journal    
DOI: 10.1186/1471-2342-9-12     Document Type: Article

References (40)

1. Briesacher BA Limcangco MR Simoni-Wastila L Doshi JA Levens SR Shea DG Stuart B The quality of antipsychotic drug prescribing in nursing homes Arch Intern Med 2005, 165(11):1280-1285. 10.1001/archinte.165.11.1280 15956008
2. Chow TW Pollock BG Milgram NW SSRIs for treatment of cognition in AD and potential disease modification Neuropsychiatric Disease and Treatment 2007, 3(5):627-636.
3. Pollock BG Mulsant BH Rosen J Mazumdar S Blakesley RE Houck PR Huber KA A double-blind comparison of citalopram and risperidone for the treatment of behavioral and psychotic symptoms associated with dementia Am J Geriatr Psychiatry 2007, 15(9):942-952. 10.1097/ JGP.0b013e3180cc1ff5 17846102
4. Tandon R Safety and tolerability: How do newer generation "atypical" antipsychotics compare? Psychiatric Quarterly 2002, 73(4):297-311. 10.1023/A:1020464017021 12418358
5. Arango V Underwood MD Mann JJ Alterations in monoamine receptors in the brain of suicide victims J Clin Psychopharmacol 1992, 12(2 Suppl):8S-12S. 1315808
6. Oquendo MA Russo SA Underwood MD Kassir SA Ellis SP Mann JJ Arango V Higher postmortem prefrontal 5-HT2A receptor binding correlates with lifetime aggression in suicide Biol Psychiatry 2006, 59(3):235-243. 10.1016/j.biopsych.2005.06.037 16140277
7. Yates M Leake A Candy JM Fairbairn AF McKeith IG Ferrier IN 5HT2 receptor changes in major depression Biological Psychiatry 1990, 27(5):489-496. 10.1016/0006-3223(90)90440-D 2310804
8. Blin J Baron JC Dubois B Crouzel C Fiorelli M Attar-Levy D Pillon B Fournier D Vidailhet M Agid Y Loss of brain 5-HT2 receptors in Alzheimer's disease: In vivo assessment with positron emission tomography and [18F]setoperone Brain 1993, 116:497-510. 10.1093/brain/ 116.3.497 8513389
9. Ngan ET Yatham LN Ruth TJ Liddle PF Decreased serotonin 2A receptor densities in neuroleptic-naive patients with schizophrenia: A PET study using [(18)F]setoperone American Journal of Psychiatry 2000, 157(6):1016-1018. 10.1176/appi.ajp.157.6.1016 10831488
10. Meltzer CC Price JC Mathis CA Greer PJ Cantwell MN Houck PR Mulsant BH Ben-Eliezer D Lopresti B DeKosky ST Reynolds CF 3rd PET imaging of serotonin type 2A receptors in late-life neuropsychiatric disorders American Journal of Psychiatry 1999, 156(12):1871-1878. 10588399
11. Massou JM Trichard C Attar-Levy D Feline A Corruble E Beaufils B Martinot JL Frontal 5-HT2A receptors studied in depressive patients during chronic treatment by selective serotonin reuptake inhibitors Psychopharmacology 1997, 133(1):99-101. 10.1007/s002130050377 9335087
12. Verhoeff NP Meyer JH Kecojevic A Hussey D Lewis R Tauscher J Zipursky RB Kapur S A voxel-by-voxel analysis [18F]setoperone PET data shows no substantial serotonin 5-HT(2A) receptor changes in schizophrenia Psychiatry Research 2000, 99(3):123-135. 10.1016/S0165-1781(00)00198-0 11068194
13. Meyer JH Kapur S Eisfeld B Brown GM Houle S DaSilva J Wilson AA Rafi-Tari S Mayberg HS Kennedy SH The effect of paroxetine on 5-HT(2A) receptors in depression: An [(18)F]setoperone PET imaging study American Journal of Psychiatry 2001, 158(1):78-85. 10.1176/appi.ajp.158.1.78 11136637
14. Vera P Zilbovicius M Chabriat H Amarenco P Kerdraon J Menard JF Amarenco G Bousser MG Rancurel G Samson Y Post-stroke changes in cortical 5-HT2 serotonergic receptors Journal of Nuclear Medicine 1996, 37(12):1976-1981. 8970517
15. Versijpt J Van Laere KJ Dumont F Decoo D Vandecapelle M Santens P Goethals I Audenaert K Slegers G Dierckx RA Korf J Imaging of the 5-HT2A system: Age-, gender-, and Alzheimer's disease-related findings Neurobiology of Aging 2003, 24(4):553-561. 10.1016/S0197-4580(02)00137-9 12714112
16. Wong DF Lever JR Hartig PR Dannals RF Villemagne V Hoffman BJ Wilson AA Ravert HT Links JM Scheffel U Wagner HN Localization of serotonin 5-HT2 receptors in living human brain by positron emission tomography using N1-([11C]-methyl)-2-Br-LSD Synapse 1987, 1:393-398. 10.1002/ syn.890010502 2905532
17. Sheline YI Mintun MA Moerlein SM Snyder AZ Greater loss of 5-HT(2A) receptors in midlife than in late life American Journal of Psychiatry 2002, 159(3):430-435. 10.1176/appi.ajp.159.3.430 11870007
18. Crouzel C Guillaume M Barre L Lemaire C Pike VW Ligands and tracers for PET studies of the 5-HT system- current status Int J Radiation Applications and Instrumentation, Part B News 1992, 19:857-870. 10.1016/ 0883-2897(92)90172-U
19. Kapur S Jones C DaSilva J Wilson A Houle S Reliability of a simple non-invasive method for the evaluation of 5-HT2 receptors using [18F]-setoperone PET imaging Nuclear Medicine Communications 1997, 18(5):395-399. 10.1097/00006231-199705000-00002 9194079
20. Lewis R Kapur S Jones C DaSilva J Brown GM Wilson AA Houle S Zipursky RB Serotonin 5-HT2 receptors in schizophrenia: A PET study using [18F]setoperone in neuroleptic-naive patients and normal subjects American Journal of Psychiatry 1999, 156(1):72-78. 9892300
21. Soares JC van Dyck CH Tan P Zoghbi SS Garg P Soufer R Baldwin RM Fujita M Staley JK Fu X Amici L Seibyl J Innis RB Reproducibility of in vivo brain measures of 5-HT2A receptors with PET and [18F]deuteroaltanserin Psychiatry Research 2001, 106(2):81-93. 10.1016/S0925-4927(01)00071-3 11306248
22. Smith GS Price JC Lopresti BJ Huang Y Simpson N Holt D Mason NS Meltzer CC Sweet RA Nichols T Shashin D Mathis CA Test-retest variability of serotonin 5-HT2A receptor binding measured with positron emission tomography and [18F]altanserin in the human brain Synapse 1998, 30(4):380-392. 10.1002/ (SICI)1098-2396(199812)30:4<380::AID-SYN5>3.0.CO;2-U 9826230
23. Price JC Lopresti BJ Meltzer CC Smith GS Mason NS Huang Y Holt DP Gunn RN Mathis CA Analyses of [(18)F]altanserin bolus injection PET data. II: consideration of radiolabeled metabolites in humans Synapse 2001, 41(1):11-21. 10.1002/syn.1055 11354009
24. Ito H Nyberg S Halldin C Lundkvist C Farde L PET imaging of central 5-HT2A receptors with carbon-11-MDL 100,907 J Nucl Med 1998, 39(1):208-214. 9443763
25. Mamo D Graff A Mizrahi R Shammi CM Romeyer F Kapur S Differential effects of aripiprazole on D2, 5-HT2, and 5-HT1A receptor occupancy in patients with schizophrenia: A triple tracer PET study American Journal of Psychiatry 2007, 164(9):1411-1417. 10.1176/appi.ajp.2007.06091479 17728427
26. Mazière B Crouzel C Venet M Stulzaft O Sanz G Ottaviani M Sejourne C Pascal O Bisserbe J Synthesis, affinity and specificity of 18F-setoperone, a potential ligand for in-vivo imaging of cortical serotonin receptors Nucl Med Biol Int J Radiat Apl Instrum Part B 1988, 15:463-468.
27. Rusjan P Mamo D Ginovart N Hussey D Vitcu I Yasuno F Tetsuya S Houle S Kapur S An automated method for the extraction of regional data from PET images Psychiatry Research 2006, 147(1):79-89. 10.1016/ j.pscychresns.2006.01.011 16797168
28. Maldjian JA Laurienti PJ Kraft RA Burdette JH An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets Neuroimage 2003, 19(3):1233-1239. 10.1016/ S1053-8119(03)00169-1 12880848
29. Seminowicz DA Mayberg HS McIntosh AR Goldapple K Kennedy S Segal Z Rafi-Tari S Limbic-frontal circuitry in major depression: A path modeling metanalysis Neuroimage 2004, 22(1):409-418. 10.1016/ j.neuroimage.2004.01.015 15110034
30. Rosen HJ Allison SC Schauer GF Gorno-Tempini ML Weiner MW Miller BL Neuroanatomical correlates of behavioural disorders in dementia Brain 2005. 1820861 16195246
31. Fischman A Bonab A Babich J Alpert N S R Elmaleh D Shoup T Williams S Rubin R Positron emission tomographic analysis of central 5-hydroxytryptamine2 receptor occupancy in healthy volunteers treated with the novel antipsychotic agent ziprasidone J Pharmacol Exp Ther 1996, 279:939-947. 8930203
32. Blin J Pappata S Kiyosawa M Crouzel C Baron J [18F]Setoperone: A new high-affinity ligand for positron emission tomography study of the serotonin-2 receptors in baboon brain in vivo Eur J Pharmacol 1988, 147:73-82. 10.1016/0014-2999(88)90635-8 3259509
33. Mintun MA Raichle ME Kilbourn MR Wooten GF Welch MJ A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography Annals of Neurology 1984, 15(3):217-227. 10.1002/ ana.410150302 6609679
34. Tauscher J Verhoeff N Christensen BK Hussey D Meyer JH Kecojevic A Javanmard M Kasper S Kapur S Serotonin 5-HT1A receptor binding potential declines with age as measured by [11C]WAY-100635 and PET Neuropsychopharmacology 2001, 24:522-530. 10.1016/S0893-133X(00)00227-X 11282252
35. Hoffman EJ Huang SC Phelps ME Quantitation in positron emission computed tomography: 1. Effect of object size J Comput Assist Tomogr 1979, 3:299-308. 438372
36. Kessler RM Ellis JR Eden M Analysis of emission tomographic scan data: limitations imposed by resolution and background J Comput Assist Tomogr 1984, 8:514-522. 10.1097/00004728-198406000-00028 6609942
37. Meltzer CC Smith G Price JC Reynolds CF 3rd Mathis CA Greer P Lopresti B Mintun MA Pollock BG Ben-Eliezer D Cantwell MN Kaye W DeKosky ST Reduced binding of [18F]altanserin to serotonin type 2A receptors in aging: persistence of effect after partial volume correction Brain Research 1998, 813(1):167-171. 10.1016/S0006-8993(98)00909-3 9824691
38. Trichard C Paillere-Martinot ML Attar-Levy D Blin J Feline A Martinot JL No serotonin 5-HT2A receptor density abnormality in the cortex of schizophrenic patients studied with PET Schizophrenia Research 1998, 31(1):13-17. 10.1016/S0920-9964(98)00014-0 9633832
39. Hurlemann R Matusch A Kuhn K Berning J Elmenhorst D Winz O Kolsch H Zilles K Wagner M Maier W Bauer A 5-HT2A receptor density is decreased in the at-risk mental state Psychopharmacology 2007, 195:579-590. 10.1007/s00213-007-0921-x 17899021
40. Adams KH Pinborg LH Svarer C Hasselbalch SG Holm S Haugbøl S Madsen K Frøkjaer V Martiny L Paulson OB Knudsen GM A database of [(18)F]-altanserin binding to 5-HT(2A) receptors in normal volunteers: normative data and relationship to physiological and demographic variables Neuroimage 2004, 21(3):1105-1113. 10.1016/ j.neuroimage.2003.10.046 15006678