메뉴 건너뛰기




Volumn 156, Issue 1, 1999, Pages 72-78

Serotonin 5-HT2 receptors in schizophrenia: A PET study using [18F]setoperone in neuroleptic-naive patients and normal subjects

Author keywords

[No Author keywords available]

Indexed keywords

NEUROLEPTIC AGENT; SEROTONIN 2 RECEPTOR; SETOPERONE; CONTRAST MEDIUM; DIAGNOSTIC AGENT; FLUORINE; PYRIMIDINONE DERIVATIVE; SEROTONIN RECEPTOR;

EID: 0032589898     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/ajp.156.1.72     Document Type: Article
Times cited : (99)

References (56)
  • 1
    • 0028855452 scopus 로고
    • Serotonin, schizophrenia and antipsychotic drug action
    • Breier A: Serotonin, schizophrenia and antipsychotic drug action. Schizophr Res 1995; 14:187-202
    • (1995) Schizophr Res , vol.14 , pp. 187-202
    • Breier, A.1
  • 2
    • 0028870605 scopus 로고
    • The evolution of the serotonin-dopamine antagonist concept
    • Hattunen M: The evolution of the serotonin-dopamine antagonist concept. J Clin Psychopharmacol 1995; 15:4S-10S
    • (1995) J Clin Psychopharmacol , vol.15
    • Hattunen, M.1
  • 4
    • 85160471768 scopus 로고
    • A serotonergic theory of schizophrenia
    • Edited by Brown S-L, van Praag HM. New York, Brunner/Mazel
    • Bleich A, Brown S-L, van Praag HM: A serotonergic theory of schizophrenia, in The Role of Serotonin in Psychiatric Disorders. Edited by Brown S-L, van Praag HM. New York, Brunner/Mazel, 1991, pp 183-214
    • (1991) The Role of Serotonin in Psychiatric Disorders , pp. 183-214
    • Bleich, A.1    Brown, S.-L.2    Van Praag, H.M.3
  • 5
    • 0017068246 scopus 로고
    • Antipsychotic drug doses and neuroleptic/dopamine receptors
    • Seeman P, Lee T, Chau-Wong M, Wong K: Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature 1976; 261:717-719
    • (1976) Nature , vol.261 , pp. 717-719
    • Seeman, P.1    Lee, T.2    Chau-Wong, M.3    Wong, K.4
  • 6
    • 0023812652 scopus 로고
    • Clozapine for the treatment-resistant schizophrenic: A double-blind comparison with chlorpromazine
    • Kane J, Honigfeld G, Singer J, Meltzer H: Clozapine for the treatment-resistant schizophrenic: a double-blind comparison with chlorpromazine. Arch Gen Psychiatry 1988; 45:789-796
    • (1988) Arch Gen Psychiatry , vol.45 , pp. 789-796
    • Kane, J.1    Honigfeld, G.2    Singer, J.3    Meltzer, H.4
  • 7
    • 0029988896 scopus 로고    scopus 로고
    • Serotonin-dopamine interaction and its relevance to schizophrenia
    • Kapur S, Remington G: Serotonin-dopamine interaction and its relevance to schizophrenia. Am J Psychiatry 1996; 153: 466-476
    • (1996) Am J Psychiatry , vol.153 , pp. 466-476
    • Kapur, S.1    Remington, G.2
  • 8
    • 0027234989 scopus 로고
    • The role of serotonin in schizophrenia: An overview of the nomenclature, distribution and alterations of serotonin receptors in the central nervous system
    • Ohuoha DC, Hyde TM, Kleinman JE: The role of serotonin in schizophrenia: an overview of the nomenclature. Psychopharmacology (Berl) 1993; 112:S5-S15
    • (1993) Psychopharmacology (Berl) , vol.112
    • Ohuoha, D.C.1    Hyde, T.M.2    Kleinman, J.E.3
  • 9
    • 0028888599 scopus 로고
    • The role of serotonin in schizophrenia and the place of serotonin-dopamine antagonist antipsychotics
    • Meltzer HY: The role of serotonin in schizophrenia and the place of serotonin-dopamine antagonist antipsychotics. J Clin Psychopharmacol 1995; 15:2S-3S
    • (1995) J Clin Psychopharmacol , vol.15
    • Meltzer, H.Y.1
  • 10
    • 0028878411 scopus 로고
    • Serotonin-dopamine antagonists and treatment of negative symptoms
    • Carpenter WT Jr: Serotonin-dopamine antagonists and treatment of negative symptoms. J Clin Psychopharmacol 1995; 15:30S-35S
    • (1995) J Clin Psychopharmacol , vol.15
    • Carpenter W.T., Jr.1
  • 11
    • 0027335564 scopus 로고
    • Serotonin2 receptor binding in blood platelets of schizophrenic patients
    • Arora RC, Meltzer HY: Serotonin2 receptor binding in blood platelets of schizophrenic patients. Psychiatry Res 1993; 47: 111-119
    • (1993) Psychiatry Res , vol.47 , pp. 111-119
    • Arora, R.C.1    Meltzer, H.Y.2
  • 13
    • 0020637328 scopus 로고
    • Characterization and regional distribution of serotonin S2 receptors in human brain
    • Schotte A, Maloteaux JM, Laduron PM: Characterization and regional distribution of serotonin S2 receptors in human brain. Brain Res 1983; 276:231-235
    • (1983) Brain Res , vol.276 , pp. 231-235
    • Schotte, A.1    Maloteaux, J.M.2    Laduron, P.M.3
  • 14
    • 0021126913 scopus 로고
    • Regional and cortical laminar distributions of serotonin S2, benzodiazepine, muscarinic, and dopamine D2 receptors in human brain
    • Luabeya MK, Maloteaux JM, Laduron PM: Regional and cortical laminar distributions of serotonin S2, benzodiazepine, muscarinic, and dopamine D2 receptors in human brain. J Neurochem 1984; 43:1068-1071
    • (1984) J Neurochem , vol.43 , pp. 1068-1071
    • Luabeya, M.K.1    Maloteaux, J.M.2    Laduron, P.M.3
  • 15
    • 0023274497 scopus 로고
    • Serotonin receptors in the human brain, IV: Autoradiographic mapping of serotonin-2 receptors
    • Pazos A, Probst A, Palacios JM: Serotonin receptors in the human brain, IV: autoradiographic mapping of serotonin-2 receptors. Neuroscience 1987; 21:123-139
    • (1987) Neuroscience , vol.21 , pp. 123-139
    • Pazos, A.1    Probst, A.2    Palacios, J.M.3
  • 16
    • 0025962706 scopus 로고
    • Autoradiography of serotonin receptor subtypes in the central nervous system
    • Radja F, LaPorte A-M, Daval GV, Verg D, Gozlan H, Hamon M: Autoradiography of serotonin receptor subtypes in the central nervous system. Neurochem Int 1991; 18:1-15
    • (1991) Neurochem Int , vol.18 , pp. 1-15
    • Radja, F.1    LaPorte, A.-M.2    Daval, G.V.3    Verg, D.4    Gozlan, H.5
  • 18
    • 0019505753 scopus 로고
    • Tritiated LSD binding in frontal cortex in schizophrenia
    • Whitaker PM, Crow TJ, Ferrier IN: Tritiated LSD binding in frontal cortex in schizophrenia. Arch Gen Psychiatry 1981; 38: 278-280
    • (1981) Arch Gen Psychiatry , vol.38 , pp. 278-280
    • Whitaker, P.M.1    Crow, T.J.2    Ferrier, I.N.3
  • 19
    • 0020652913 scopus 로고
    • Preliminary studies of human cortical 5-HT2 receptors and their involvement in schizophrenia and neuroleptic drug action
    • Reynolds GP, Rossor MN, Iversen LL: Preliminary studies of human cortical 5-HT2 receptors and their involvement in schizophrenia and neuroleptic drug action. J Neural Transm Suppl 1983; 18:273-277
    • (1983) J Neural Transm Suppl , vol.18 , pp. 273-277
    • Reynolds, G.P.1    Rossor, M.N.2    Iversen, L.L.3
  • 21
    • 0025921604 scopus 로고
    • Serotonin2 (5-HT2) receptor binding in the frontal cortex of schizophrenic patients
    • Arora RC, Meltzer HY: Serotonin2 (5-HT2) receptor binding in the frontal cortex of schizophrenic patients. J Neural Transm Gen Sect 1991; 85:19-29
    • (1991) J Neural Transm Gen Sect , vol.85 , pp. 19-29
    • Arora, R.C.1    Meltzer, H.Y.2
  • 25
    • 0030592323 scopus 로고    scopus 로고
    • Decreased frontal cortical serotonin2A receptors in schizophrenia
    • Dean B, Hayes W: Decreased frontal cortical serotonin2A receptors in schizophrenia. Schizophr Res 1996; 21:133-139
    • (1996) Schizophr Res , vol.21 , pp. 133-139
    • Dean, B.1    Hayes, W.2
  • 26
    • 0030273870 scopus 로고    scopus 로고
    • 5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia
    • Burnet PW, Eastwood SL, Harrison PJ: 5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia. Neuropsychopharmacology 1996; 15:442-455
    • (1996) Neuropsychopharmacology , vol.15 , pp. 442-455
    • Burnet, P.W.1    Eastwood, S.L.2    Harrison, P.J.3
  • 27
    • 0023820533 scopus 로고
    • 18F]Setoperone: A new high-affinity ligand for positron emission tomography study of the serotonin-2 receptors in baboon brain in vivo
    • 18F]Setoperone: a new high-affinity ligand for positron emission tomography study of the serotonin-2 receptors in baboon brain in vivo. Eur J Pharmacol 1988; 147:73-82
    • (1988) Eur J Pharmacol , vol.147 , pp. 73-82
    • Blin, J.1    Pappata, S.2    Kiyosawa, M.3    Crouzel, C.4    Baron, J.C.5
  • 32
    • 0026749234 scopus 로고
    • Blood-cerebrospinal fluid and blood-brain barriers imaged by 18F-labeled metabolites of 18F-setoperone studied in humans using positron emission tomography
    • Blin J, Crouzel C: Blood-cerebrospinal fluid and blood-brain barriers imaged by 18F-labeled metabolites of 18F-setoperone studied in humans using positron emission tomography. J Neurochem 1992; 58:2303-2310
    • (1992) J Neurochem , vol.58 , pp. 2303-2310
    • Blin, J.1    Crouzel, C.2
  • 43
    • 0030004584 scopus 로고    scopus 로고
    • Estimation of neocortical serotonin-2 receptor binding potential by single-dose fluorine-18-setoperone kinetic PET data analysis
    • Petit-Taboue MC, Landeau B, Osmont A, Tillet I, Barre L, Baron JC: Estimation of neocortical serotonin-2 receptor binding potential by single-dose fluorine-18-setoperone kinetic PET data analysis. J Nucl Wed 1996; 37:95-104
    • (1996) J Nucl Wed , vol.37 , pp. 95-104
    • Petit-Taboue, M.C.1    Landeau, B.2    Osmont, A.3    Tillet, I.4    Barre, L.5    Baron, J.C.6
  • 45
    • 0027447488 scopus 로고
    • The detection of age-related decrease of dopamine D1, D2 and serotonin 5-HT2 receptors in living human brain
    • Iyo M, Yamasaki T: The detection of age-related decrease of dopamine D1, D2 and serotonin 5-HT2 receptors in living human brain. Prog Neuropsychopharmacol Biol Psychiatry 1993; 17:415-421
    • (1993) Prog Neuropsychopharmacol Biol Psychiatry , vol.17 , pp. 415-421
    • Iyo, M.1    Yamasaki, T.2
  • 48
    • 0027749398 scopus 로고
    • Serotonin receptor responsivity in schizophrenia
    • Kahn RS, Davidson M: Serotonin receptor responsivity in schizophrenia. Int Clin Psychopharmacol 1993; 8:47-51
    • (1993) Int Clin Psychopharmacol , vol.8 , pp. 47-51
    • Kahn, R.S.1    Davidson, M.2
  • 49
    • 0027296447 scopus 로고
    • m-Chlorophenylpiperazine effects in neuroleptic-free schizophrenic patients: Evidence implicating serotonergic systems in the positive symptoms of schizophrenia
    • Krystal JH, Seibyl JP, Price LH, Woods SW, Heninger GR, Aghajanian GK, Charney DS: m-Chlorophenylpiperazine effects in neuroleptic-free schizophrenic patients: evidence implicating serotonergic systems in the positive symptoms of schizophrenia. Arch Gen Psychiatry 1993; 50:624-635
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 624-635
    • Krystal, J.H.1    Seibyl, J.P.2    Price, L.H.3    Woods, S.W.4    Heninger, G.R.5    Aghajanian, G.K.6    Charney, D.S.7
  • 50
    • 0029897502 scopus 로고    scopus 로고
    • Enhancement of the prolactin response to d-fenfluramine in drug-naive schizophrenic patients
    • Abel KM, O'Keane V, Murray RM: Enhancement of the prolactin response to d-fenfluramine in drug-naive schizophrenic patients. Br J Psychiatry 1996; 168:57-60
    • (1996) Br J Psychiatry , vol.168 , pp. 57-60
    • Abel, K.M.1    O'Keane, V.2    Murray, R.M.3
  • 51
    • 0030693979 scopus 로고    scopus 로고
    • Serotonergic function and negative and depressive symptomatology in schizophrenia and major depression
    • Abel KM, O'Keane V, Murray RM, Cleare AJ: Serotonergic function and negative and depressive symptomatology in schizophrenia and major depression. Psychoneuroendocrinology 1997; 22:539-548
    • (1997) Psychoneuroendocrinology , vol.22 , pp. 539-548
    • Abel, K.M.1    O'Keane, V.2    Murray, R.M.3    Cleare, A.J.4
  • 52
  • 54
    • 0029037226 scopus 로고
    • Effect of clozapine on d-fenfluramine-evoked neuroendocrine responses in schizophrenia and its relationship to clinical improvement
    • Curtis VA, Wright P, Reveley A, Kerwin R, Lucey JV: Effect of clozapine on d-fenfluramine-evoked neuroendocrine responses in schizophrenia and its relationship to clinical improvement. Br J Psychiatry 1995; 166:642-646
    • (1995) Br J Psychiatry , vol.166 , pp. 642-646
    • Curtis, V.A.1    Wright, P.2    Reveley, A.3    Kerwin, R.4    Lucey, J.V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.