메뉴 건너뛰기




Volumn 19, Issue 4, 2009, Pages 368-373

Building the world's best hearing aid; regulation of cell fate in the cochlea

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; NOTCH RECEPTOR; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR SOX2;

EID: 68949146586     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gde.2009.06.004     Document Type: Review
Times cited : (25)

References (45)
  • 1
    • 34250667165 scopus 로고    scopus 로고
    • Anatomical predictions of hearing in the North Atlantic right whale
    • Parks S.E., Ketten D.R., O'Malley J.T., and Arruda J. Anatomical predictions of hearing in the North Atlantic right whale. Anat Rec (Hoboken) 290 (2007) 734-744
    • (2007) Anat Rec (Hoboken) , vol.290 , pp. 734-744
    • Parks, S.E.1    Ketten, D.R.2    O'Malley, J.T.3    Arruda, J.4
  • 2
    • 0015189077 scopus 로고
    • The embryonic and postnatal development of the inner ear of the mouse
    • Sher A.E. The embryonic and postnatal development of the inner ear of the mouse. Acta Otolaryngol Suppl 285 (1971) 1-77
    • (1971) Acta Otolaryngol Suppl , vol.285 , pp. 1-77
    • Sher, A.E.1
  • 3
    • 0020549516 scopus 로고
    • Studies on cell migration and axon guidance in the developing distal auditory system on the mouse
    • Carney P.R., and Silver J. Studies on cell migration and axon guidance in the developing distal auditory system on the mouse. J Comp Neurol 215 (1983) 359-369
    • (1983) J Comp Neurol , vol.215 , pp. 359-369
    • Carney, P.R.1    Silver, J.2
  • 4
    • 0032007713 scopus 로고    scopus 로고
    • The development of the vertebrate inner ear
    • Torres M., and Giraldez F. The development of the vertebrate inner ear. Mech Dev 71 (1998) 5-21
    • (1998) Mech Dev , vol.71 , pp. 5-21
    • Torres, M.1    Giraldez, F.2
  • 6
    • 4644342396 scopus 로고    scopus 로고
    • From placode to polarization: new tunes in inner ear development
    • Barald K.F., and Kelley M.W. From placode to polarization: new tunes in inner ear development. Development 131 (2004) 4119-4130
    • (2004) Development , vol.131 , pp. 4119-4130
    • Barald, K.F.1    Kelley, M.W.2
  • 7
    • 0032079370 scopus 로고    scopus 로고
    • Development of the mouse inner ear and origin of its sensory organs
    • Morsli H., Choo D., Ryan A., Johnson R., and Wu D.K. Development of the mouse inner ear and origin of its sensory organs. J Neurosci 18 (1998) 3327-3335
    • (1998) J Neurosci , vol.18 , pp. 3327-3335
    • Morsli, H.1    Choo, D.2    Ryan, A.3    Johnson, R.4    Wu, D.K.5
  • 8
    • 0034212915 scopus 로고    scopus 로고
    • A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea
    • Zhang N., Martin G.V., Kelley M.W., and Gridley T. A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea. Curr Biol 10 (2000) 659-662
    • (2000) Curr Biol , vol.10 , pp. 659-662
    • Zhang, N.1    Martin, G.V.2    Kelley, M.W.3    Gridley, T.4
  • 9
    • 43249111952 scopus 로고    scopus 로고
    • Bmp4 is essential for the formation of the vestibular apparatus that detects angular head movements
    • Chang W., Lin Z., Kulessa H., Hebert J., Hogan B.L., and Wu D.K. Bmp4 is essential for the formation of the vestibular apparatus that detects angular head movements. PLoS Genet 11 (2008) e1000050
    • (2008) PLoS Genet , vol.11
    • Chang, W.1    Lin, Z.2    Kulessa, H.3    Hebert, J.4    Hogan, B.L.5    Wu, D.K.6
  • 12
    • 33646164664 scopus 로고    scopus 로고
    • Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear
    • Brooker R., Hozumi K., and Lewis J. Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear. Development 133 (2006) 1277-1286
    • (2006) Development , vol.133 , pp. 1277-1286
    • Brooker, R.1    Hozumi, K.2    Lewis, J.3
  • 13
    • 33645758812 scopus 로고    scopus 로고
    • The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear
    • This work uses a tissue-specific deletion of Jagged1 to demonstrate that Jagged1 signaling is required upstream of Sox2 to mediate formation of prosensory patches within the inner ear.
    • Kiernan A.E., Xu J., and Gridley T. The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear. PLoS Genet 2 (2006) e4. This work uses a tissue-specific deletion of Jagged1 to demonstrate that Jagged1 signaling is required upstream of Sox2 to mediate formation of prosensory patches within the inner ear.
    • (2006) PLoS Genet , vol.2
    • Kiernan, A.E.1    Xu, J.2    Gridley, T.3
  • 14
    • 34347355519 scopus 로고    scopus 로고
    • Notch signaling is needed to maintain, but not to initiate, the formation of prosensory patches in chick inner ear
    • Daudet N., Ariza-McNaughton L., and Lewis J. Notch signaling is needed to maintain, but not to initiate, the formation of prosensory patches in chick inner ear. Development 134 (2007) 2369-2378
    • (2007) Development , vol.134 , pp. 2369-2378
    • Daudet, N.1    Ariza-McNaughton, L.2    Lewis, J.3
  • 15
    • 40949091386 scopus 로고    scopus 로고
    • Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea
    • Hayashi T., Kokubo H., Hartman B.H., Ray C.A., Reh T.A., and Bermingham-McDonogh O. Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea. Dev Biol 316 (2008) 87-99
    • (2008) Dev Biol , vol.316 , pp. 87-99
    • Hayashi, T.1    Kokubo, H.2    Hartman, B.H.3    Ray, C.A.4    Reh, T.A.5    Bermingham-McDonogh, O.6
  • 16
    • 57449114544 scopus 로고    scopus 로고
    • Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea
    • This paper demonstrated the existence of mutual antagonism between Sox2 and Atoh1 and suggested that the interplay between these molecules plays a key role in mediating the number of cells that develop as hair cells versus supporting cells. The results also suggest that while Sox2 is required for prosensory specification, subsequent downregulation of Sox2 is required for hair cell development.
    • Dabdoub A., Puligilla C., Jones J.M., Fritzsch B., Cheah K.S., Pevny L.H., and Kelley M.W. Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea. Proc Natl Acad Sci U S A 105 (2008) 18396-18401. This paper demonstrated the existence of mutual antagonism between Sox2 and Atoh1 and suggested that the interplay between these molecules plays a key role in mediating the number of cells that develop as hair cells versus supporting cells. The results also suggest that while Sox2 is required for prosensory specification, subsequent downregulation of Sox2 is required for hair cell development.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 18396-18401
    • Dabdoub, A.1    Puligilla, C.2    Jones, J.M.3    Fritzsch, B.4    Cheah, K.S.5    Pevny, L.H.6    Kelley, M.W.7
  • 17
    • 14044258714 scopus 로고    scopus 로고
    • Two contrasting roles for Notch activity in chick inner ear development: specification of prosensory patches and lateral inhibition of hair-cell differentiation
    • Daudet N., and Lewis J. Two contrasting roles for Notch activity in chick inner ear development: specification of prosensory patches and lateral inhibition of hair-cell differentiation. Development 132 (2005) 541-551
    • (2005) Development , vol.132 , pp. 541-551
    • Daudet, N.1    Lewis, J.2
  • 19
    • 54449095812 scopus 로고    scopus 로고
    • Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear
    • Zou D., Erickson C., Kim E., Jin D., Fritzsch B., and Xu P. Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear. Hum Mol Genet 17 (2008) 3340-3356
    • (2008) Hum Mol Genet , vol.17 , pp. 3340-3356
    • Zou, D.1    Erickson, C.2    Kim, E.3    Jin, D.4    Fritzsch, B.5    Xu, P.6
  • 20
    • 34547697201 scopus 로고    scopus 로고
    • Expression of LHX3 and SOX2 during mouse inner ear development
    • Hume C.R., Bratt D.L., and Oesterle E.C. Expression of LHX3 and SOX2 during mouse inner ear development. Gene Expr Patterns 7 (2007) 798-807
    • (2007) Gene Expr Patterns , vol.7 , pp. 798-807
    • Hume, C.R.1    Bratt, D.L.2    Oesterle, E.C.3
  • 21
    • 49049120372 scopus 로고    scopus 로고
    • Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans
    • This manuscript demonstrated auditory deficits in patients with Pallister-Hall Syndrome that were correlated with cochlear defects in a mouse model of Pallister-Hall. A direct inhibitory effect of sonic hedgehog on prosensory formation was also demonstrated in vitro.
    • Driver E.C., Pryor S.P., Hill P., Turner J., Ruther U., Biesecker L.G., Griffith A.J., and Kelley M.W. Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans. J Neurosci 28 (2008) 7350-7358. This manuscript demonstrated auditory deficits in patients with Pallister-Hall Syndrome that were correlated with cochlear defects in a mouse model of Pallister-Hall. A direct inhibitory effect of sonic hedgehog on prosensory formation was also demonstrated in vitro.
    • (2008) J Neurosci , vol.28 , pp. 7350-7358
    • Driver, E.C.1    Pryor, S.P.2    Hill, P.3    Turner, J.4    Ruther, U.5    Biesecker, L.G.6    Griffith, A.J.7    Kelley, M.W.8
  • 22
    • 27644446538 scopus 로고    scopus 로고
    • The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear
    • Kiernan A.E., Cordes R., Kopan R., Gossler A., and Gridley T. The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development 132 (2005) 4353-4362
    • (2005) Development , vol.132 , pp. 4353-4362
    • Kiernan, A.E.1    Cordes, R.2    Kopan, R.3    Gossler, A.4    Gridley, T.5
  • 23
    • 0034127584 scopus 로고    scopus 로고
    • Overexpression of Math1 induces robust production of extra hair cells in postnatal inner ears
    • Zheng J.L., and Gao W.Q. Overexpression of Math1 induces robust production of extra hair cells in postnatal inner ears. Nat Neurosci 3 (2000) 580-586
    • (2000) Nat Neurosci , vol.3 , pp. 580-586
    • Zheng, J.L.1    Gao, W.Q.2
  • 24
    • 0038118296 scopus 로고    scopus 로고
    • Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo
    • Kawamoto K., Ishimoto S., Minoda R., Brough D.E., and Raphael Y. Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo. J Neurosci 23 (2003) 4395-4400
    • (2003) J Neurosci , vol.23 , pp. 4395-4400
    • Kawamoto, K.1    Ishimoto, S.2    Minoda, R.3    Brough, D.E.4    Raphael, Y.5
  • 25
    • 13744263559 scopus 로고    scopus 로고
    • Math1 regulates development of the sensory epithelium in the mammalian cochlea
    • Woods C., Montcouquiol M., and Kelley M.W. Math1 regulates development of the sensory epithelium in the mammalian cochlea. Nat Neurosci 7 (2004) 1310-1318
    • (2004) Nat Neurosci , vol.7 , pp. 1310-1318
    • Woods, C.1    Montcouquiol, M.2    Kelley, M.W.3
  • 26
    • 52949112282 scopus 로고    scopus 로고
    • Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer
    • This work utilized a newly developed technique to transfer genes into otocyst cells in embryonic mice in vivo. Hair cells generated through transfection of Atoh1 were shown to be functional and to have mechanosensitive properties that are comparable with endogenous hair cells.
    • Gubbels S.P., Woessner D.W., Mitchell J.C., Ricci A.J., and Brigande J.V. Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer. Nature 455 (2008) 537-541. This work utilized a newly developed technique to transfer genes into otocyst cells in embryonic mice in vivo. Hair cells generated through transfection of Atoh1 were shown to be functional and to have mechanosensitive properties that are comparable with endogenous hair cells.
    • (2008) Nature , vol.455 , pp. 537-541
    • Gubbels, S.P.1    Woessner, D.W.2    Mitchell, J.C.3    Ricci, A.J.4    Brigande, J.V.5
  • 27
    • 1842816370 scopus 로고    scopus 로고
    • Mouse FGF15 is the ortholog of human and chick FGF19, but is not uniquely required for otic induction
    • Wright T.J., Ladher R., McWhirter J., Murre C., Schoenwolf G.C., and Mansour G.L. Mouse FGF15 is the ortholog of human and chick FGF19, but is not uniquely required for otic induction. Dev Biol 269 (2004) 264-275
    • (2004) Dev Biol , vol.269 , pp. 264-275
    • Wright, T.J.1    Ladher, R.2    McWhirter, J.3    Murre, C.4    Schoenwolf, G.C.5    Mansour, G.L.6
  • 28
    • 0042831024 scopus 로고    scopus 로고
    • Fgf3 and Fgf10 are required for mouse otic placode induction
    • Wright T.J., and Mansour S.L. Fgf3 and Fgf10 are required for mouse otic placode induction. Development 130 (2003) 3379-3390
    • (2003) Development , vol.130 , pp. 3379-3390
    • Wright, T.J.1    Mansour, S.L.2
  • 30
    • 0036829715 scopus 로고    scopus 로고
    • Fgf8 and Fgf3 are required for zebrafish ear placode induction, maintenance and inner ear patterning
    • Leger S., and Brand M. Fgf8 and Fgf3 are required for zebrafish ear placode induction, maintenance and inner ear patterning. Mech Dev 119 (2002) 91-108
    • (2002) Mech Dev , vol.119 , pp. 91-108
    • Leger, S.1    Brand, M.2
  • 31
    • 0036337492 scopus 로고    scopus 로고
    • Fgf3 and Fgf8 are required together for formation of the otic placode and vesicle
    • Maroon H., Walshe J., Mahmood R., Kiefer P., Dickson C., and Mason I. Fgf3 and Fgf8 are required together for formation of the otic placode and vesicle. Development 129 (2002) 2099-2108
    • (2002) Development , vol.129 , pp. 2099-2108
    • Maroon, H.1    Walshe, J.2    Mahmood, R.3    Kiefer, P.4    Dickson, C.5    Mason, I.6
  • 32
    • 0033833143 scopus 로고    scopus 로고
    • Competence, specification and commitment in otic placode induction
    • Groves A.K., and Bronner-Fraser M. Competence, specification and commitment in otic placode induction. Development 127 (2000) 3489-3499
    • (2000) Development , vol.127 , pp. 3489-3499
    • Groves, A.K.1    Bronner-Fraser, M.2
  • 33
    • 3042655429 scopus 로고    scopus 로고
    • Genetic interactions underlying otic placode induction and formation
    • Solomon K.S., Kwak S.J., and Fritz A. Genetic interactions underlying otic placode induction and formation. Dev Dyn 230 (2004) 419-433
    • (2004) Dev Dyn , vol.230 , pp. 419-433
    • Solomon, K.S.1    Kwak, S.J.2    Fritz, A.3
  • 35
    • 44949241690 scopus 로고    scopus 로고
    • Fgf20 is required for sensory epithelial specification in the developing cochlea
    • Hayashi T., Ray C.A., and Bermingham-McDonogh O. Fgf20 is required for sensory epithelial specification in the developing cochlea. J Neursci 28 (2008) 5991-5999
    • (2008) J Neursci , vol.28 , pp. 5991-5999
    • Hayashi, T.1    Ray, C.A.2    Bermingham-McDonogh, O.3
  • 36
    • 33846933074 scopus 로고    scopus 로고
    • Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti
    • Hayashi T., Cunningham D., and Bermingham-McDonogh O. Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti. Dev Dyn 236 (2007) 525-533
    • (2007) Dev Dyn , vol.236 , pp. 525-533
    • Hayashi, T.1    Cunningham, D.2    Bermingham-McDonogh, O.3
  • 37
    • 34447524005 scopus 로고    scopus 로고
    • Disruption of fibroblast growth factor receptor 3 signaling results in defects in cellular differentiation, neuronal pattering, and hearing impairment
    • Puligilla C., Feng F., Ishikawa K., Bertuzzi S., Dabdoub A., Griffith A.J., Fritzsch B., and Kelley M.W. Disruption of fibroblast growth factor receptor 3 signaling results in defects in cellular differentiation, neuronal pattering, and hearing impairment. Dev Dyn 236 (2007) 1905-1917
    • (2007) Dev Dyn , vol.236 , pp. 1905-1917
    • Puligilla, C.1    Feng, F.2    Ishikawa, K.3    Bertuzzi, S.4    Dabdoub, A.5    Griffith, A.J.6    Fritzsch, B.7    Kelley, M.W.8
  • 38
    • 34548567099 scopus 로고    scopus 로고
    • Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea
    • Jacques B.E., Montcouquiol M.E., Layman E.M., Lewandoski M., and Kelley M.W. Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea. Development 134 (2007) 3021-3029
    • (2007) Development , vol.134 , pp. 3021-3029
    • Jacques, B.E.1    Montcouquiol, M.E.2    Layman, E.M.3    Lewandoski, M.4    Kelley, M.W.5
  • 39
    • 0030000960 scopus 로고    scopus 로고
    • Activation of Fgf-4 and HoxD gene expression by BMP-2 expressing cells in the developing chick limb
    • Duprez D.M., Kostakopoulou K., Francis-West P.H., Tickle C., and Brickell P.M. Activation of Fgf-4 and HoxD gene expression by BMP-2 expressing cells in the developing chick limb. Development 122 (1996) 1821-1828
    • (1996) Development , vol.122 , pp. 1821-1828
    • Duprez, D.M.1    Kostakopoulou, K.2    Francis-West, P.H.3    Tickle, C.4    Brickell, P.M.5
  • 40
    • 0029954477 scopus 로고    scopus 로고
    • Morphological and molecular characterization of retinoic acid-induced limb duplications in mice
    • Niederreither K., Ward S.J., Dolle P., and Chambon P. Morphological and molecular characterization of retinoic acid-induced limb duplications in mice. Dev Biol 176 (1996) 185-198
    • (1996) Dev Biol , vol.176 , pp. 185-198
    • Niederreither, K.1    Ward, S.J.2    Dolle, P.3    Chambon, P.4
  • 41
    • 0032976694 scopus 로고    scopus 로고
    • Sonic hedgehog (SHH) specifies muscle pattern at tissue and cellular chick level, in the chick limb bud
    • Duprez D., Lapointe F., Edom-Vovard F., Kostakopoulou K., and Robson L. Sonic hedgehog (SHH) specifies muscle pattern at tissue and cellular chick level, in the chick limb bud. Mech Dev 82 (1999) 151-163
    • (1999) Mech Dev , vol.82 , pp. 151-163
    • Duprez, D.1    Lapointe, F.2    Edom-Vovard, F.3    Kostakopoulou, K.4    Robson, L.5
  • 42
    • 0032693836 scopus 로고    scopus 로고
    • Sonic hedgehog signaling during digit pattern duplication after application of recombinant protein and expressing cells
    • Wada N., Kawakami Y., and Nohno T. Sonic hedgehog signaling during digit pattern duplication after application of recombinant protein and expressing cells. Dev Growth Differ 41 (1999) 567-574
    • (1999) Dev Growth Differ , vol.41 , pp. 567-574
    • Wada, N.1    Kawakami, Y.2    Nohno, T.3
  • 43
    • 0036340168 scopus 로고    scopus 로고
    • Misexpression of dHAND induces ectopic digits in the developing limb bud in the absence of direct DNA binding
    • McFadden D.G., McAnally J., Richardson J.A., Charite J., and Olson E.N. Misexpression of dHAND induces ectopic digits in the developing limb bud in the absence of direct DNA binding. Development 129 (2002) 3077-3088
    • (2002) Development , vol.129 , pp. 3077-3088
    • McFadden, D.G.1    McAnally, J.2    Richardson, J.A.3    Charite, J.4    Olson, E.N.5
  • 44
    • 48549084248 scopus 로고    scopus 로고
    • Jxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of Corti
    • This work identifies a point mutation in Sobp/Jcx1 as the defect in the Jackson Circler mouse line. The cochleae of these animals are shown to have numerous defects including an overall shortening, patterning defects including mirror image duplications of the organ of Corti and aberrant planar cell polarity.
    • Chen Z., Montcouquiol M., Calderon R., Jenkins N.A., Copeland N.G., Kelley M.W., and Noben-Trauth K. Jxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of Corti. J Neurosci 28 (2008) 6633-6641. This work identifies a point mutation in Sobp/Jcx1 as the defect in the Jackson Circler mouse line. The cochleae of these animals are shown to have numerous defects including an overall shortening, patterning defects including mirror image duplications of the organ of Corti and aberrant planar cell polarity.
    • (2008) J Neurosci , vol.28 , pp. 6633-6641
    • Chen, Z.1    Montcouquiol, M.2    Calderon, R.3    Jenkins, N.A.4    Copeland, N.G.5    Kelley, M.W.6    Noben-Trauth, K.7
  • 45
    • 0027429455 scopus 로고
    • Descriptive and experimental analysis of the epithelial remodellings that control semicircular canal formation in the developing mouse inner ear
    • Martin P., and Swanson G.J. Descriptive and experimental analysis of the epithelial remodellings that control semicircular canal formation in the developing mouse inner ear. Dev Biol 159 (1993) 549-558
    • (1993) Dev Biol , vol.159 , pp. 549-558
    • Martin, P.1    Swanson, G.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.