Plasminogen activator inhibitor-1 regulates integrin αvβ3 expression and autocrine transforming growth factor β signaling

Journal of Biological Chemistry

Volumn 284, Issue 31, 2009, Pages 20708-20717

  Pedroja, Benjamin S ^a   Kang, Leah E ^a   Imas, Alex O ^a   Carmeliet, Peter ^b   Bernstein, Audrey M ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOCRINE LOOP; CELL SURFACES; COLLAGEN DEPOSITION; EXTRACELLULAR MATRICES; FOCAL ADHESIONS; INTEGRINS; KNOCK OUTS; MOUSE EMBRYONIC FIBROBLASTS; MYOFIBROBLASTS; OVER-EXPRESSION; PLASMINOGEN ACTIVATOR INHIBITOR; PLASMINOGEN ACTIVATOR INHIBITOR-1; RGD PEPTIDE; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTORS; UROKINASE PLASMINOGEN; WILD-TYPE CELLS;

AMINES; BIOACTIVITY; CELL CULTURE; CELL MEMBRANES; CHEMICAL ACTIVATION; DISEASE CONTROL; ENZYME INHIBITION; FIBROBLASTS; NUCLEIC ACIDS; PEPTIDES; RNA; SIGNALING; TISSUE;

MOS CAPACITORS;

ARGINYLGLYCYLASPARTIC ACID; PLASMIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; SMAD2 PROTEIN; SMAD3 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA2; VITRONECTIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOCRINE EFFECT; CELL NUCLEUS; CELL SURFACE; CONTROLLED STUDY; EMBRYO; ENDOCYTOSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROSIS; FOCAL ADHESION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MOUSE; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE;

ANIMALS; AUTOCRINE COMMUNICATION; CELL LINE; CELL MEMBRANE; CELL NUCLEUS; COLLAGEN; DNA, COMPLEMENTARY; ENDOCYTOSIS; FIBRINOLYSIN; FIBROBLASTS; FOCAL ADHESIONS; HUMANS; INTEGRIN ALPHAVBETA3; MICE; MICE, KNOCKOUT; MINK; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 68949143128     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.018804     Document Type: Article

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