Study of inhibition effect of Herceptin on interaction between Heregulin and ErbB Receptors HER3/HER2 by single-molecule force spectroscopy

Experimental Cell Research

Volumn 315, Issue 16, 2009, Pages 2847-2855

  Shi, Xiaoli ^a   Xu, Li ^a   Yu, Junping ^a   Fang, Xiaohong ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Atomic force microscopy; Epidermal growth factor receptor; Herceptin; Heregulin; Ligand receptor interaction; Single molecule force spectroscopy

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; HETERODIMER; NEU DIFFERENTIATION FACTOR; TRASTUZUMAB;

ANTINEOPLASTIC ACTIVITY; ARTICLE; ATOMIC FORCE MICROSCOPY; CONTROLLED STUDY; DIMERIZATION; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MALIGNANT NEOPLASTIC DISEASE; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SINGLE MOLECULE FORCE SPECTROSCOPY;

EID: 68949131106     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2009.05.023     Document Type: Article

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