Molecular modeling studies to predict the possible binding modes of endomorphin analogs in μ opioid receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 18, 2009, Pages 5387-5391

  Liu, Xin ^a   Kai, Ming ^a   Jin, Lian ^a   Wang, Rui ^a,b  

^a LANZHOU UNIVERSITY   (China)

^b HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Opioid receptor; Endomorphin analogs; Molecular docking; Molecular dynamics simulation

Indexed keywords

ANALGESIC AGENT; ENDOMORPHIN 1; ENDOMORPHIN 2; ENDORPHIN DERIVATIVE; MU OPIATE RECEPTOR; TYROSYLPROLYLPHENYLALANYLALANINE DERIVATIVE; TYROSYLPROLYLPHENYLALANYLVALINE DERIVATIVE; TYROSYLPROLYLTRYPTOPHYLALANINE DERIVATIVE; TYROSYLPROLYLTRYPTOPHYLGLYCINE DERIVATIVE; TYROSYLPROLYLTRYPTOPHYLVALINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; MOLECULAR DOCKING; MOLECULAR MODEL; PHOSPHOLIPID BILAYER; SIMULATION;

COMPUTER SIMULATION; HUMANS; LIGANDS; MODELS, MOLECULAR; OLIGOPEPTIDES; PROTEIN BINDING; RECEPTORS, OPIOID, MU;

EID: 68949116093     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.07.121     Document Type: Article

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