Pain inhibition by endomorphins

Annals of the New York Academy of Sciences

Volumn 897, Issue , 1999, Pages 154-164

  Przewłocki, Ryszard ^a   Labuz D ^a   Mika, J ^a   Przewlocka B ^a   Tomboly, Cs ^b   Toth, G ^b  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOMORPHIN 1; ENDOMORPHIN 2; FORMALDEHYDE; MORPHINE;

ALLODYNIA; ANALGESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; CANNULA; CONFERENCE PAPER; CONTROLLED STUDY; CRUSH TRAUMA; DOSE RESPONSE; INFLAMMATION; NEUROPATHY; NONHUMAN; PAIN; PRESSURE; RAT; SCIATIC NERVE; SPINAL ANESTHESIA; TAIL FLICK TEST;

ANIMALIA;

EID: 0033387589     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb07887.x     Document Type: Conference Paper

References (24)

1. 1. Hackler, L., J.E. Zadina, L-J. Ge & A.J. Kastin. 1997. Isolation of relatively large amounts of endomorphin-1 and endomorphin-2 from human brain cortex. Peptides 18: 1635-1639.
2. 2. Zadina, J.E., L. Hackler, G. Lin-Jun & A.J. Kastin. 1997. A potent and selective endogenous agonist for the μ-opiate receptor. Nature 386: 499-502.
3. 3. Galina, Z.H. & A.J. Kastin. 1986. Existence of antiopiate systems as illustrated by MIF-1/Tyr-MIF-1. Life Sci. 39 (23): 2153-2159.
4. 4. Zadina, J.E., A.J. Kastin, D. Kersh & A. Wyatt. 1992. Tyr-MIF-1 and hemorphin can act as opiate agonists as well as antagonists in the guinea pig ileum. Life Sci. 51: 869-885.
5. 5. Goldberg, I.E., G.C. Rossi, S.R. Letchworth, J.P. Mathis, J. Ryan-Moro, L. Leventhal, W. Su & D. Emmel. 1998. Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain. J. Pharmacol. Exp. Ther. 286 (2): 1007-1013.
6. 6. Przewłocka, B., J. Mika, D. Łabuz, G. Toth & R. Przewłocki. 1999. Spinal analgesic action of endomorphins in acute, inflammatory and neuropathic pain in rats. Eur. J. Pharmacol. 367: 189-196.
7. 7. Stone, L.S., C.A. Fairbanks, T.M. Laughlin, H.O. Nguyen, T.M. Bushy, M.W. Wessendorf & G.L. Wilcox. 1997. Spinal analgesic actions of the new endogenous opioid peptides endomorphin-1 and -2. NeuroReport 8: 3131-3135.
8. 8. Martin-Schild, S., A.A. Gerall, A.J. Kastin & J.E. Zadina. 1998. Endomorphin-2 is an endogenous opioid in primary sensory afferent fibers. Peptides 19 (10): 1783-1789.
9. 9. Martin-Schild, S., J.E. Zadina, A.A. Gerall, A. Vigh & A.J. Kastin. 1997. Localization of endomorphin-2-like immunoreactivity in the rat medulla and spinal cord. Peptides 18: 1641-1649.
10. 10. Pierce, T.L., M.D. Grahek & M.W. Wessendorf. 1998. Immunoreactivity for endomorphin-2 occurs in primary afferents in rats and monkey. NeuroReport 9: 385-389.
11. 11. Schmidhammer, H., W.P. Burkard, L. Eggstein-Aeppli & C.F.C. Smith. 1989. Synthesis and biological evaluation of 14-alkoxymorphinans. 2.1 (-)-N-(cyclopropylmethyl)-4, 14-dimethoxymorphinan-6-one, a selective μ opioid receptor antagonist. J. Med. Chem. 32: 418-21.
12. 12. Hruby, V.J., G. Toth, C.A. Gehrig, L.-F. Kao, R. Knapp, G.K. Lui, H.I. Yamamura, T.H. Kramer, P. Davis & T.F. Burks. 1991. Topographically designed analogues of [D-Pen,D-Pen5]enkephalin. J. Med. Chem. 34: 1823-1830.
13. 13. Ossipov, M.H., Y. Lopez, M.L. Nichols, D. Bian & F. Porreca. 1995. Inhibition by spinal morphine of the tail-flick response is attenuated in rats with nerve ligation injury. Neurosci. Lett. 199: 83-86.
14. 14. Ossipov, M.H., Y. Lopez, M.L. Nichols, D. Bian & F. Porreca. 1995. The loss of antinociceptive efficacy of spinal morphine in rats with nerve ligation injury is prevented by reducing spinal afferent drive. Neurosci. Lett. 199: 87-90.
15. 15. De Koning, P., J.H. Brakkee & W.H. Gispen. 1986. Methods for producing a reproducible crush in the sciatic and tibial nerve of the rat and rapid and precise testing of return of sensory function. Beneficial effects of melanocortins. J. Neurol. Sci. 74: 237-246.
16. 16. Hunter, J.C., K.R. Gogas, L.R. Hedley, L.O. Jacobson, L. Kassotakis, J. Thompson & D.J. Fontana. 1997. The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain. Eur. J. Pharmacol. 324: 153-160.
17. 17. Nichols, M.L., Y. Lopez, M.H. Ossipov, D. Bian & F. Porreca. 1997. Enhancement of the antiallodynic and antinociceptive efficacy of spinal morphine by antisera to dynorphin A (1-13) or MK-801 in a nerve-ligation model of peripheral neuropathy. Pain 69: 317-322.
18. 18. Yaksh, T.L., J.W. Pogrel, Y.W. Lee & S.R. Chaplan. 1995. Reversal of nerve ligation-induced allodynia by spinal alpha-2 adrenoceptor agonists. J. Pharmacol. Exp. Ther. 272: 207-214.
19. 19. Bian, D., M.L. Nichols, M.H. Ossipov, J. Lai & F. Porreca. 1995. Allodynic efficacy of morphine in a model of neuropathic pain in rats. NeuroReport 6: 1981-1984.
20. 20. Arner, S. & B.A. Myerson. 1988. Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain. Pain 33: 11-23.
21. 21. Twycross, R.G. 1982. Morphine and diamorphine in the terminally ill patient. Acta Anesthesiol. Scand. 74: 128-134.
22. 22. Machelska, H., D. Łabuz, R. Przewłocki & B. Przewłocka. 1997. Inhibition of nitric oxide synthasc enhances antinociception mediated by mu, delta and kappa opioid receptors in acute and prolonged pain in the rat spinal cord. J. Pharmacol. Exp. Ther. 282: 977-984
23. 23. Przewłocka, B., H. Machelska & R. Przewłocki. 1993. Inhibition of nitric oxide synthase enhances morphine antinociception in the rat spinal cord.. Life Sci. 53: 1-5.
24. 24. Burford, N.T., L.M. Tolbert & W. Sadee. 1998. Specific G protein activation and μ-opioid receptor internalization caused by morphine, DAMGO and endomorphin I. Eur. J. Pharmacol. 342: 123-126.