메뉴 건너뛰기




Volumn 22, Issue 4, 2009, Pages 469-475

Pediatric pharmacology in the first year of life

Author keywords

Maturation; Pharmacodynamics; Pharmacogenetics; Pharmacokinetics

Indexed keywords

ACICLOVIR; ANESTHETIC AGENT; APROTININ; BUPIVACAINE; CLONIDINE; DEXMEDETOMIDINE; FENTANYL; GLUCURONIDE; MERCAPTOPURINE; MIDAZOLAM; MILRINONE; MORPHINE; PARACETAMOL; PROPOFOL; REMIFENTANIL; TRAMADOL; VANCOMYCIN;

EID: 68949114216     PISSN: 09527907     EISSN: None     Source Type: Journal    
DOI: 10.1097/ACO.0b013e32832bc7ff     Document Type: Review
Times cited : (36)

References (50)
  • 1
    • 41749105125 scopus 로고    scopus 로고
    • The problems in scaling adult drug doses to children
    • Johnson TN. The problems in scaling adult drug doses to children. Arch Dis. Child 2008; 93:207-211.
    • (2008) Arch Dis. Child , vol.93 , pp. 207-211
    • Johnson, T.N.1
  • 2
    • 33746803672 scopus 로고    scopus 로고
    • Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children
    • Johnson TN, Rostami-Hodjegan A, Tucker GT. Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children. Clin Pharmacokinet 2006; 45:931-956.
    • (2006) Clin Pharmacokinet , vol.45 , pp. 931-956
    • Johnson, T.N.1    Rostami-Hodjegan, A.2    Tucker, G.T.3
  • 3
  • 4
    • 52649130373 scopus 로고    scopus 로고
    • Whole body physiologically-based pharmacokinetic models: Their use in clinical drug development
    • Edginton AN, Theil FP, Schmitt W, Willmann S. Whole body physiologically-based pharmacokinetic models: their use in clinical drug development. Expert Opin Drug Metab Toxicol 2008; 4:1143-1152.
    • (2008) Expert Opin Drug Metab Toxicol , vol.4 , pp. 1143-1152
    • Edginton, A.N.1    Theil, F.P.2    Schmitt, W.3    Willmann, S.4
  • 5
    • 40549143738 scopus 로고    scopus 로고
    • Facilitation of drug evaluation in children by population methods and modelling
    • Tod M, Jullien V, Pons G. Facilitation of drug evaluation in children by population methods and modelling. Clin Pharmacokinet 2008; 47:231-243.
    • (2008) Clin Pharmacokinet , vol.47 , pp. 231-243
    • Tod, M.1    Jullien, V.2    Pons, G.3
  • 6
    • 41149180911 scopus 로고    scopus 로고
    • Mechanism-based concepts of size and maturity in pharmacokinetics
    • Anderson BJ, Holford NH. Mechanism-based concepts of size and maturity in pharmacokinetics. Annu Rev Pharmacol Toxicol 2008; 48:303-332.
    • (2008) Annu Rev Pharmacol Toxicol , vol.48 , pp. 303-332
    • Anderson, B.J.1    Holford, N.H.2
  • 7
    • 0003043542 scopus 로고
    • The possible effects of the aggregation of the molecules of haemoglobin on its dissociation curves
    • Hill AV. The possible effects of the aggregation of the molecules of haemoglobin on its dissociation curves. J Physiol 1910; 14:iv-vii.
    • (1910) J Physiol , vol.14 , pp. 4-7
    • Hill, A.V.1
  • 8
    • 4043147979 scopus 로고
    • A flexible growth function for empirical use
    • Richards FJ. A flexible growth function for empirical use. J Exp Bot 1959; 10:290-301.
    • (1959) J Exp Bot , vol.10 , pp. 290-301
    • Richards, F.J.1
  • 9
    • 23844533652 scopus 로고    scopus 로고
    • Tramadol disposition in the very young: An attempt to assess in vivo cytochrome P450 2D6 activity
    • Allegaert K, Anderson BJ, Verbesselt R, et al. Tramadol disposition in the very young: an attempt to assess in vivo cytochrome P450 2D6 activity. Br J Anaesth 2005; 95:231-239.
    • (2005) Br J Anaesth , vol.95 , pp. 231-239
    • Allegaert, K.1    Anderson, B.J.2    Verbesselt, R.3
  • 10
    • 0035170198 scopus 로고    scopus 로고
    • Pharmacokinetics of oral acyclovir in neonates and in infants: A population analysis
    • Tod M, Lokiec F, Bidault R, et al. Pharmacokinetics of oral acyclovir in neonates and in infants: a population analysis. Antimicrob Agents Chemother 2001; 45:150-157.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 150-157
    • Tod, M.1    Lokiec, F.2    Bidault, R.3
  • 11
    • 34548331855 scopus 로고    scopus 로고
    • Clonidine disposition in children; A population analysis
    • Potts AL, Larsson P, Eksborg S, et al. Clonidine disposition in children; a population analysis. Pediatr Anesth 2007; 17:924-933.
    • (2007) Pediatr Anesth , vol.17 , pp. 924-933
    • Potts, A.L.1    Larsson, P.2    Eksborg, S.3
  • 12
    • 56549088409 scopus 로고    scopus 로고
    • Population pharmacokinetic and pharmacogenetic analysis of 6-mercaptopurine in paediatric patients with acute lymphoblastic leukaemia
    • Hawwa AF, Collier PS, Millership JS, et al. Population pharmacokinetic and pharmacogenetic analysis of 6-mercaptopurine in paediatric patients with acute lymphoblastic leukaemia. Br J Clin Pharmacol 2008; 66:826-837.
    • (2008) Br J Clin Pharmacol , vol.66 , pp. 826-837
    • Hawwa, A.F.1    Collier, P.S.2    Millership, J.S.3
  • 13
    • 38449118819 scopus 로고    scopus 로고
    • Inter-individual variability in propofol pharmacokinetics in preterm and term neonates
    • Allegaert K, Peeters MY, Verbesselt R, et al. Inter-individual variability in propofol pharmacokinetics in preterm and term neonates. Br J Anaesth 2007; 99:864-870.
    • (2007) Br J Anaesth , vol.99 , pp. 864-870
    • Allegaert, K.1    Peeters, M.Y.2    Verbesselt, R.3
  • 14
    • 34547857015 scopus 로고    scopus 로고
    • Remifentanil-midazolam sedation for paediatric patients receiving mechanical ventilation after cardiac surgery
    • Rigby-Jones AE, Priston MJ, Sneyd JR, et al. Remifentanil-midazolam sedation for paediatric patients receiving mechanical ventilation after cardiac surgery. Br J Anaesth 2007; 99:252-261.
    • (2007) Br J Anaesth , vol.99 , pp. 252-261
    • Rigby-Jones, A.E.1    Priston, M.J.2    Sneyd, J.R.3
  • 15
    • 33845453628 scopus 로고    scopus 로고
    • Vancomycin pharmaco-kinetics in preterm neonates and the prediction of adult clearance
    • Anderson BJ, Allegaert K, Van den Anker JN, et al. Vancomycin pharmaco-kinetics in preterm neonates and the prediction of adult clearance. Br J Clin Pharmacol 2007; 63:75-84.
    • (2007) Br J Clin Pharmacol , vol.63 , pp. 75-84
    • Anderson, B.J.1    Allegaert, K.2    Van Den Anker, J.N.3
  • 16
    • 67649415182 scopus 로고    scopus 로고
    • Mechanistic basis of using body size and maturation to predict clearance in humans
    • Anderson BJ, Holford NH. Mechanistic basis of using body size and maturation to predict clearance in humans. Drug Metab Pharmacokinet 2009; 24:25-36.
    • (2009) Drug Metab Pharmacokinet , vol.24 , pp. 25-36
    • Anderson, B.J.1    Holford, N.H.2
  • 17
    • 54249163567 scopus 로고    scopus 로고
    • Morphine pharmacokinetics and pharmacodynamics in preterm and term neonates: Secondary results from the NEOPAIN trial
    • Anand KJ, Anderson BJ, Holford NH, et al. Morphine pharmacokinetics and pharmacodynamics in preterm and term neonates: secondary results from the NEOPAIN trial. Br J Anaesth 2008; 101:680-689.
    • (2008) Br J Anaesth , vol.101 , pp. 680-689
    • Anand, K.J.1    Anderson, B.J.2    Holford, N.H.3
  • 18
    • 47349104647 scopus 로고    scopus 로고
    • Dexmedetomidine disposition in children: A population analysis
    • Potts AL, Warman GR, Anderson BJ. Dexmedetomidine disposition in children: a population analysis. Paediatr Anaesth 2008; 18:722-730.
    • (2008) Paediatr Anaesth , vol.18 , pp. 722-730
    • Potts, A.L.1    Warman, G.R.2    Anderson, B.J.3
  • 19
    • 34748836928 scopus 로고    scopus 로고
    • Maturational pharmacokinetics of single intravenous bolus of propofol
    • Allegaert K, de Hoon J, Verbesselt R, et al. Maturational pharmacokinetics of single intravenous bolus of propofol. Paediatr Anaesth 2007; 17:1028-1034.
    • (2007) Paediatr Anaesth , vol.17 , pp. 1028-1034
    • Allegaert, K.1    De Hoon, J.2    Verbesselt, R.3
  • 20
    • 59849122627 scopus 로고    scopus 로고
    • Human renal function maturation: A quantitative description using weight and postmenstrual age
    • Rhodin MM, Anderson BJ, Peters AM, etal. Human renal function maturation: a quantitative description using weight and postmenstrual age. Pediatr Nephrol 2009; 24:67-76.
    • (2009) Pediatr Nephrol , vol.24 , pp. 67-76
    • Rhodin, M.M.1    Anderson, B.J.2    Peters, A.M.3
  • 21
    • 34247896966 scopus 로고    scopus 로고
    • Population pharmacokinetics and dosing regimen design of milrinone in preterm infants
    • Paradisis M, Jiang X, McLachlan AJ, et al. Population pharmacokinetics and dosing regimen design of milrinone in preterm infants. Arch Dis Child Fetal Neonatal Ed 2007; 92:F204-F209.
    • (2007) Arch Dis Child Fetal Neonatal Ed , vol.92
    • Paradisis, M.1    Jiang, X.2    McLachlan, A.J.3
  • 22
    • 0141857724 scopus 로고    scopus 로고
    • Developmental pharmacology: Drug disposition, action, and therapy in infants and children
    • Kearns GL, Abdel-Rahman SM, Alander SW, et al. Developmental pharmacology: drug disposition, action, and therapy in infants and children. N Engl J Med 2003; 349:1157-1167.
    • (2003) N Engl J Med , vol.349 , pp. 1157-1167
    • Kearns, G.L.1    Abdel-Rahman, S.M.2    Alander, S.W.3
  • 23
    • 51849104277 scopus 로고    scopus 로고
    • I.V. acetaminophen pharmacoki-netics in neonates after multiple doses
    • Palmer GM, Atkins M, Anderson BJ, et al. I.V. acetaminophen pharmacoki-netics in neonates after multiple doses. Br J Anaesth 2008; 101:523-530.
    • (2008) Br J Anaesth , vol.101 , pp. 523-530
    • Palmer, G.M.1    Atkins, M.2    Anderson, B.J.3
  • 24
    • 37549022653 scopus 로고    scopus 로고
    • Midazolam potentiates nociceptive behavior, sensitizes cutaneous reflexes, and is devoid of sedative action in neonatal rats
    • Koch SC, Fitzgerald M, Hathway GJ. Midazolam potentiates nociceptive behavior, sensitizes cutaneous reflexes, and is devoid of sedative action in neonatal rats. Anesthesiology 2008; 108:122-129.
    • (2008) Anesthesiology , vol.108 , pp. 122-129
    • Koch, S.C.1    Fitzgerald, M.2    Hathway, G.J.3
  • 25
    • 37549039830 scopus 로고    scopus 로고
    • Paradoxical effects of midazolam in the very young
    • Tobin JR. Paradoxical effects of midazolam in the very young. Anesthesiology 2008; 108:6-7.
    • (2008) Anesthesiology , vol.108 , pp. 6-7
    • Tobin, J.R.1
  • 26
    • 23944523856 scopus 로고    scopus 로고
    • Dreaming during anaesthesia in children: Incidence, nature and associations
    • Huang GH, Davidson AJ, Stargatt R. Dreaming during anaesthesia in children: incidence, nature and associations. Anaesthesia 2005; 60:854-861.
    • (2005) Anaesthesia , vol.60 , pp. 854-861
    • Huang, G.H.1    Davidson, A.J.2    Stargatt, R.3
  • 27
    • 34748834617 scopus 로고    scopus 로고
    • Awareness during pediatric anesthesia: What is the position of European pediatric anesthesiologists?
    • Engelhardt T, Petroz GC, McCheyne A, Bissonnette B. Awareness during pediatric anesthesia: what is the position of European pediatric anesthesiologists? Paediatr Anaesth 2007; 17:1066-1070.
    • (2007) Paediatr Anaesth , vol.17 , pp. 1066-1070
    • Engelhardt, T.1    Petroz, G.C.2    McCheyne, A.3    Bissonnette, B.4
  • 29
    • 33846142845 scopus 로고    scopus 로고
    • Comparative evaluation of Bispectral Index and Narcotrend Index in children below 5 years of age
    • Wallenborn J, Kluba K, Olthoff D. Comparative evaluation of Bispectral Index and Narcotrend Index in children below 5 years of age. Paediatr Anaesth 2007; 17:140-147.
    • (2007) Paediatr Anaesth , vol.17 , pp. 140-147
    • Wallenborn, J.1    Kluba, K.2    Olthoff, D.3
  • 30
    • 38549130711 scopus 로고    scopus 로고
    • Bispectral index and middle latency auditory evoked potentials in children younger than two-years-old
    • Lamas A, Lopez-Herce J, Sancho L, et al. Bispectral index and middle latency auditory evoked potentials in children younger than two-years-old. Anesth Analg 2008; 106:426-432.
    • (2008) Anesth Analg , vol.106 , pp. 426-432
    • Lamas, A.1    Lopez-Herce, J.2    Sancho, L.3
  • 31
    • 37249022944 scopus 로고    scopus 로고
    • The electroencephalograph during anesthesia and emergence in infants and children
    • Davidson AJ, Sale SM, Wong C, et al. The electroencephalograph during anesthesia and emergence in infants and children. Paediatr Anaesth 2008;18:60-70.
    • (2008) Paediatr Anaesth , vol.18 , pp. 60-70
    • Davidson, A.J.1    Sale, S.M.2    Wong, C.3
  • 32
    • 38449110433 scopus 로고    scopus 로고
    • EEG variables as measures of arousal during propofol anaesthesia for general surgery in children: Rational selection and age dependence
    • Jeleazcov C, Schmidt J, Schmitz B, et al. EEG variables as measures of arousal during propofol anaesthesia for general surgery in children: rational selection and age dependence. Br J Anaesth 2007; 99:845-854.
    • (2007) Br J Anaesth , vol.99 , pp. 845-854
    • Jeleazcov, C.1    Schmidt, J.2    Schmitz, B.3
  • 33
    • 0029762738 scopus 로고    scopus 로고
    • Development of sensory information processing: The ontogenesis of opioid binding sites in nociceptive afferents and their significance in the clinical setting
    • Freye E. Development of sensory information processing: the ontogenesis of opioid binding sites in nociceptive afferents and their significance in the clinical setting. Acta Anaesthesiol Scand Suppl 1996; 109:98-101.
    • (1996) Acta Anaesthesiol Scand Suppl , vol.109 , pp. 98-101
    • Freye, E.1
  • 34
    • 41949118720 scopus 로고    scopus 로고
    • Covariates of tramadol disposition in the first months of life
    • Allegaert K, van den Anker JN, de Hoon JN, et al. Covariates of tramadol disposition in the first months of life. Br J Anaesth 2008; 100:525-532.
    • (2008) Br J Anaesth , vol.100 , pp. 525-532
    • Allegaert, K.1    Van Den Anker, J.N.2    De Hoon, J.N.3
  • 35
    • 35348849215 scopus 로고    scopus 로고
    • Introduction and audit of intravenous paracetamol at a tertiary paediatric teaching hospital
    • Palmer GM, Chen SP, Smith KR, Hardikar W. Introduction and audit of intravenous paracetamol at a tertiary paediatric teaching hospital. Anaesth Intensive Care 2007; 35:702-706.
    • (2007) Anaesth Intensive Care , vol.35 , pp. 702-706
    • Palmer, G.M.1    Chen, S.P.2    Smith, K.R.3    Hardikar, W.4
  • 36
    • 41749124574 scopus 로고    scopus 로고
    • Hepatic tolerance of repeated intravenous paracetamol administration in neonates
    • Allegaert K, Rayyan M, De Rijdt T, et al. Hepatic tolerance of repeated intravenous paracetamol administration in neonates. Paediatr Anaesth 2008; 18:388-392.
    • (2008) Paediatr Anaesth , vol.18 , pp. 388-392
    • Allegaert, K.1    Rayyan, M.2    De Rijdt, T.3
  • 37
    • 33845522032 scopus 로고    scopus 로고
    • Intravenous paracetamol for postoperative analgesia in a 4-day-old term neonate
    • Agrawal S, Fitzsimons JJ, Horn V, Petros A. Intravenous paracetamol for postoperative analgesia in a 4-day-old term neonate. Paediatr Anaesth 2007; 17:70-71.
    • (2007) Paediatr Anaesth , vol.17 , pp. 70-71
    • Agrawal, S.1    Fitzsimons, J.J.2    Horn, V.3    Petros, A.4
  • 38
    • 34347272698 scopus 로고    scopus 로고
    • Not all intravenous paracetamol formulations are created equal
    • Allegaert K, Murat I, Anderson BJ. Not all intravenous paracetamol formulations are created equal. Paediatr Anaesth 2007; 17:811-812.
    • (2007) Paediatr Anaesth , vol.17 , pp. 811-812
    • Allegaert, K.1    Murat, I.2    Anderson, B.J.3
  • 39
    • 34748832821 scopus 로고    scopus 로고
    • Intravenous paracetamol: The 'Stockholm protocol' for postoperative analgesia of term and preterm neonates
    • Bartocci M, Lundeberg S. Intravenous paracetamol: the 'Stockholm protocol' for postoperative analgesia of term and preterm neonates. Paediatr Anaesth 2007; 17:1120-1121.
    • (2007) Paediatr Anaesth , vol.17 , pp. 1120-1121
    • Bartocci, M.1    Lundeberg, S.2
  • 40
    • 33846677487 scopus 로고    scopus 로고
    • Acetaminophen-induced hepatic failure with encephalopathy in a newborn
    • Walls L, Baker CF, Sarkar S. Acetaminophen-induced hepatic failure with encephalopathy in a newborn. J Perinatol 2007; 27:133-135.
    • (2007) J Perinatol , vol.27 , pp. 133-135
    • Walls, L.1    Baker, C.F.2    Sarkar, S.3
  • 41
    • 0030690167 scopus 로고    scopus 로고
    • Maturation of hepatosomal mono-oxygenation and glucuronidation activities in pre and full-term infants as studied using the [15N]methacetin urine test
    • Krumbiegel P, Domke S, Morseburg B, et al. Maturation of hepatosomal mono-oxygenation and glucuronidation activities in pre and full-term infants as studied using the [15N]methacetin urine test. Acta Paediatr 1997; 86:1236-1240.
    • (1997) Acta Paediatr , vol.86 , pp. 1236-1240
    • Krumbiegel, P.1    Domke, S.2    Morseburg, B.3
  • 42
    • 44649128114 scopus 로고    scopus 로고
    • Pharmacokinetics and analgesic effects of intravenous propacetamol vs rectal paracetamol in children after major craniofacial surgery
    • Prins SA, Van Dijk M, Van Leeuwen P, et al. Pharmacokinetics and analgesic effects of intravenous propacetamol vs rectal paracetamol in children after major craniofacial surgery. Paediatr Anaesth 2008; 18:582-592.
    • (2008) Paediatr Anaesth , vol.18 , pp. 582-592
    • Prins, S.A.1    Van Dijk, M.2    Van Leeuwen, P.3
  • 43
    • 38549137844 scopus 로고    scopus 로고
    • Intravenous clonidine infusion in infants after cardiovascular surgery
    • Pohl-Schickinger A, Lemmer J, Hubler M, et al. Intravenous clonidine infusion in infants after cardiovascular surgery. Paediatr Anaesth 2008; 18:217-222.
    • (2008) Paediatr Anaesth , vol.18 , pp. 217-222
    • Pohl-Schickinger, A.1    Lemmer, J.2    Hubler, M.3
  • 44
    • 41749106471 scopus 로고    scopus 로고
    • Hemodynamic effects of dexmedetomidine sedation for CT imaging studies
    • Mason KP, Zgleszewski SE, Prescilla R, et al. Hemodynamic effects of dexmedetomidine sedation for CT imaging studies. Paediatr Anaesth 2008; 18:393-402.
    • (2008) Paediatr Anaesth , vol.18 , pp. 393-402
    • Mason, K.P.1    Zgleszewski, S.E.2    Prescilla, R.3
  • 45
    • 41749089155 scopus 로고    scopus 로고
    • High dose dexmedetomidine as the sole sedative for pediatric MRI
    • Mason KP, Zurakowski D, Zgleszewski SE, etal. High dose dexmedetomidine as the sole sedative for pediatric MRI. Paediatr Anaesth 2008; 18:403-411.
    • (2008) Paediatr Anaesth , vol.18 , pp. 403-411
    • Mason, K.P.1    Zurakowski, D.2    Zgleszewski, S.E.3
  • 46
    • 37549071486 scopus 로고    scopus 로고
    • The effects of dexmedetomidine on cardiac electrophysiology in children
    • Hammer GB, Drover DR, Cao H, et al. The effects of dexmedetomidine on cardiac electrophysiology in children. Anesth Analg 2008; 106:79-83.
    • (2008) Anesth Analg , vol.106 , pp. 79-83
    • Hammer, G.B.1    Drover, D.R.2    Cao, H.3
  • 47
    • 48249130453 scopus 로고    scopus 로고
    • The use of aprotinin in pediatric cardiac surgery: Should we bid 'good riddance' or are we throwing out the baby with the bath water?
    • Twite MD, Hammer GB. The use of aprotinin in pediatric cardiac surgery: should we bid 'good riddance' or are we throwing out the baby with the bath water? Paediatr Anaesth 2008; 18:809-811.
    • (2008) Paediatr Anaesth , vol.18 , pp. 809-811
    • Twite, M.D.1    Hammer, G.B.2
  • 48
    • 37749042740 scopus 로고    scopus 로고
    • Aprotinin and renal dysfunction after pediatric cardiac surgery
    • Szekely A, Sapi E, Breuer T, et al. Aprotinin and renal dysfunction after pediatric cardiac surgery. Paediatr Anaesth 2008; 18:151-159.
    • (2008) Paediatr Anaesth , vol.18 , pp. 151-159
    • Szekely, A.1    Sapi, E.2    Breuer, T.3
  • 49
    • 37748999178 scopus 로고    scopus 로고
    • The use of aprotinin in children undergoing operative repair of isolated atrial septal defects
    • Chiravuri SD, Voepel-Lewis T, Devaney EJ, Malviya S. The use of aprotinin in children undergoing operative repair of isolated atrial septal defects. Paediatr Anaesth 2008; 18:145-150.
    • (2008) Paediatr Anaesth , vol.18 , pp. 145-150
    • Chiravuri, S.D.1    Voepel-Lewis, T.2    Devaney, E.J.3    Malviya, S.4
  • 50
    • 48249146197 scopus 로고    scopus 로고
    • A randomized, controlled •• trial of aprotinin in neonates undergoing open-heart surgery
    • Williams GD, Ramamoorthy C, Pentcheva K, et al. A randomized, controlled •• trial of aprotinin in neonates undergoing open-heart surgery. Paediatr Anaesth 2008; 18:812-819.
    • (2008) Paediatr Anaesth , vol.18 , pp. 812-819
    • Williams, G.D.1    Ramamoorthy, C.2    Pentcheva, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.