Prostate-specific Klf6 inactivation impairs anterior prostate branching morphogenesis through increased activation of the Shh pathway

Journal of Biological Chemistry

Volumn 284, Issue 31, 2009, Pages 21057-21065

  Leow, Ching Ching ^a,c   Wang, Bu Er ^a   Ross, Jed ^a   Chan, Sara M ^a   Zha, Jiping ^a   Carano, Richard A D ^a   Frantz, Gretchen ^a   Shen, Michael M ^b   de Sauvage, Frederic J ^a,d   Gao, Wei Qiang ^a,d  

^a GENENTECH INC   (United States)

^b Columbia University College of Physicians and Surgeons ^*  (United States)

^c MEDIMMUNE   (United States)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRANCHING MORPHOGENESIS; ELEVATED LEVEL; MOUSE MODELS; PATHWAY COMPONENTS; PROSTATE CANCERS; TUMOR SUPPRESSION; ZINC FINGER TRANSCRIPTION FACTOR;

PLATINUM COMPOUNDS; TRANSCRIPTION FACTORS; ZINC;

MORPHOLOGY;

DESMIN; KRUPPEL LIKE FACTOR 6; PROTEIN PATCHED; SMOOTH MUSCLE ACTIN; SONIC HEDGEHOG PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRANCHING MORPHOGENESIS; CONTROLLED STUDY; ENZYME INACTIVATION; EXON; GENE DELETION; GENE EXPRESSION; GENE LOSS; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTATE; PROTEIN DEFECT; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; BETA-GALACTOSIDASE; BONE MORPHOGENETIC PROTEIN 4; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE SILENCING; HEDGEHOG PROTEINS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MICE; MORPHOGENESIS; MUSCLE, SMOOTH; ORGAN SPECIFICITY; PROSTATE; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; UP-REGULATION;

ERINACEIDAE;

EID: 68949103879     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.001776     Document Type: Article

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