Tuning inflammation in tuberculosis: the role of decoy receptors

Microbes and Infection

Volumn 11, Issue 10-11, 2009, Pages 821-827

  Di Liberto, Diana ^a   Caccamo, Nadia ^a   Meraviglia, Serena ^a   Guggino, Giuliana ^a   La Manna, Marco P ^a   Sireci, Guido ^a   Salerno, Alfredo ^a   Dieli, Francesco ^a  

^a UNIVERSITY OF PALERMO   (Italy)

Author keywords

Chemokines; Cytokines; D6; Decoy receptors; Immunopathology; Inflammation; Mycobacterium tuberculosis; TIR8 SIGIRR

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; BETA CHEMOKINE; CCX CKR RECEPTOR; CHEMOKINE; CHEMOKINE RECEPTOR; CYTOKINE; CYTOKINE RECEPTOR; D6 RECEPTOR; DUFFY ANTIGEN RECEPTOR FOR CHEMOKINE; G PROTEIN COUPLED RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA; NEUTRALIZING ANTIBODY; PHORBOL 13 ACETATE 12 MYRISTATE; TIR8 RECEPTOR; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; CYTOKINE RELEASE; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOPATHOLOGY; INFLAMMATION; MAMMAL; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; T LYMPHOCYTE SUBPOPULATION; TISSUE INJURY; TUBERCULOSIS;

ANIMALS; HUMANS; INFLAMMATION; MICE; MYCOBACTERIUM TUBERCULOSIS; RECEPTORS, CYTOKINE; TUBERCULOSIS;

MYCOBACTERIUM TUBERCULOSIS;

EID: 68849113932     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2009.05.004     Document Type: Short Survey

References (49)

1. Rossi D., and Zlotnik A. The biology of chemokines and their receptors. Annu. Rev. Immunol. 18 (2000) 217-242
2. Mantovani A., Locati M., Vecchi A., Sozzani S., and Allavena P. Decoy receptors: a strategy to regulate inflammatory cytokines and chemokines. Trends Immunol. 22 (2001) 328-336
3. Nibbs R., Graham G., and Rot A. Chemokines on the move: control by the chemokine "interceptors" Duffy blood group antigen and D6. Semin. Immunol. 15 (2003) 287-294
4. Graham G.J. D6 and the atypical chemokine receptor family: novel regulators of immune and inflammatory processes. Eur. J. Immunol. 39 (2009) 342-351
5. Miller L.H., Mason S.J., Dvorak J.A., McGinniss M.H., and Rothman I.K. Erythrocyte receptors for [Plasmodium knowlesi] malaria: Duffy blood group determinants. Science 189 (1975) 561-563
6. Townson J.R., and Nibbs R.J. Characterization of mouse CCX-CKR, a receptor for the lymphocyte-attracting chemokines TECK/mCCL25, SLC/mCCL21 and MIP-3beta/mCCL19: comparison to human CCX-CKR. Eur. J. Immunol. 32 (2002) 1230-1241
7. Nibbs R.J., Wylie S.M., Yang J., Landau N.R., and Graham G.J. Cloning and characterization of a novel promiscuous human beta-chemokine receptor D6. J. Biol. Chem. 272 (1997) 32078-32083
8. Weber M., Blair E., Simpson C.V., O'Hara M., Blackburn P.E., Rot A., Graham G.J., and Nibbs R.J. The chemokine receptor D6 constitutively traffics to and from the cell surface to internalize and degrade chemokines. Mol. Biol. Cell 15 (2004) 2492-2508
9. Blackburn P.E., Simpson C.V., Nibbs R.J., O'Hara M., Booth R., Poulos J., Isaacs N.W., and Graham G.J. Purification and biochemical characterization of the D6 chemokine receptor. Biochem. J. 379 (2004) 263-272
10. Galliera E., Jala V.R., Trent J.O., Bonecchi R., Signorelli P., Lefkowitz R.J., Mantovani A., Locati M., and Haribabu B. beta-Arrestin-dependent constitutive internalization of the human chemokine decoy receptor D6. J. Biol. Chem. 279 (2004) 25590-25597
11. Garlanda C., Maina V., Martinez de la Torre Y., Nebuloni M., and Locati M. Inflammatory reaction and implantation: the new entries PTX3 and D6. Placenta 29 Suppl. B (2008) 129-134
12. McKimmie C.S., Fraser A.R., Hansell C., Gutierrez L., Philipsen S., Connell L., Rot A., Kurowska-Stolarska M., Carreno P., Pruenster M., Chu C.C., Lombardi G., Halsey C., McInnes I.B., Liew F.Y., Nibbs R.J., and Graham G.J. Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1. J. Immunol. 181 (2008) 8171-8181
13. -/- mice with experimental autoimmune encephalomyelitis. J. Immunol. 176 (2006) 4399-4409
14. Wu F.Y., Ou Z.L., Feng L.Y., Luo J.M., Wang L.P., Shen Z.Z., and Shao Z.M. Chemokine decoy receptor D6 plays a negative role in human breast cancer. Mol. Cancer Res. 6 (2008) 1276-1288
15. Mantovani A., Locati M., Polentarutti N., Vecchi A., and Garlanda C. Extracellular and intracellular decoys in the tuning of inflammatory cytokines and Toll-like receptors: the new entry TIR8/SIGIRR. J. Leukoc. Biol. 75 (2004) 738-742
16. Polentarutti N., Rol G.P., Muzio M., Bosisio D., Camnasio M., Riva F., Zoja C., Benigni A., Tomasoni S., Vecchi A., Garlanda C., and Mantovani A. Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR. Eur. Cytokine Netw. 14 (2003) 211-218
17. Wald D., Qin J., Zhao Z., Qian Y., Naramura M., Tian L., Towne J., Sims J.E., Stark G.R., and Li X. SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Nat. Immunol. 4 (2003) 920-927
18. Garlanda C., Riva F., Veliz T., Polentarutti N., Pasqualini F., Radaelli E., Sironi M., Nebuloni M., Zorini E.O., Scanziani E., and Mantovani A. Increased susceptibility to colitis-associated cancer of mice lacking TIR8, an inhibitory member of the interleukin-1 receptor family. Cancer Res. 67 (2007) 6017-6021
19. Garlanda C., Di Liberto D., Vecchi A., La Manna M.P., Buracchi C., Caccamo N., Salerno A., Dieli F., and Mantovani A. Damping excessive inflammation and tissue damage in Mycobacterium tuberculosis infection by Toll IL-1 receptor 8/single Ig IL-1-related receptor, a negative regulator of IL-1/TLR signaling. J. Immunol. 179 (2007) 3119-3125
20. Romani L., and Puccetti P. Controlling pathogenic inflammation to fungi. Expert Rev. Anti Infect. Ther. 5 (2007) 1007-1017
21. Bozza S., Zelante T., Moretti S., Bonifazi P., DeLuca A., D'Angelo C., Giovannini G., Garlanda C., Boon L., Bistoni F., Puccetti P., Mantovani A., and Romani L. Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection. J. Immunol. 180 (2008) 4022-4031
22. Lech M., Kulkarni O.P., Pfeiffer S., Savarese E., Krug A., Garlanda C., Mantovani A., and Anders H.J. Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens. J. Exp. Med. 205 (2008) 1879-1888
23. Marshak-Rothstein A., and Rifkin I.R. Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease. Annu. Rev. Immunol. 25 (2007) 419-441
24. Lau C.M., Broughton C., Tabor A.S., Akira S., Flavell R.A., Mamula M.J., Christensen S.R., Shlomchik M.J., Viglianti G.A., Rifkin I.R., and Marshak-Rothstein A. RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. J. Exp. Med. 202 (2005) 1171-1177
25. Boule M.W., Broughton C., Mackay F., Akira S., Marshak-Rothstein A., and Rifkin I.R. Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes. J. Exp. Med. 199 (2004) 1631-1640
26. Pawar R.D., Ramanjaneyulu A., Kulkarni O.P., Lech M., Segerer S., and Anders H.J. Inhibition of Toll-like receptor-7 [TLR-7] or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus. J. Am. Soc. Nephrol. 18 (2007) 1721-1731
27. Christensen S.R., Shupe J., Nickerson K., Kashgarian M., Flavell R.A., and Shlomchik M.J. Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity 25 (2006) 417-428
28. Subramanian S., Tus K., Li Q.Z., Wang A., Tian X.H., Zhou J., Liang C., Bartov G., McDaniel L.D., Zhou X.J., Schultz R.A., and Wakeland E.K. A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 9970-9975
29. Wu X., and Peng S.L. Toll-like receptor 9 signaling protects against murine lupus. Arthritis Rheum. 54 (2006) 336-342
30. Flynn J.L., and Chan J. Immunology of tuberculosis. Annu. Rev. Immunol. 19 (2001) 93-129
31. Feng C.G., Bean A.G., Hooi H., Briscoe H., and Britton W.J. Increase in gamma interferon-secreting CD8(+), as well as CD4(+), T cells in lungs following aerosol infection with Mycobacterium tuberculosis. Infect. Immun. 67 (1999) 3242-3247
32. Orme I.M. The immunopathogenesis of tuberculosis: a new working hypothesis. Trends Microbiol. 6 (1998) 94-97
33. Nathan C. Points of control in inflammation. Nature 420 (2002) 846-852
34. Mantovani A. The chemokine system: redundancy for robust outputs. Immunol. Today 20 (1999) 254-257
35. Roach D.R., Briscoe H., Saunders B., France M.P., Riminton S., and Britton W.J. Secreted lymphotoxin-alpha is essential for the control of an intracellular bacterial infection. J. Exp. Med. 193 (2001) 239-246
36. Bean A.G., Roach D.R., Briscoe H., France M.P., Korner H., Sedgwick J.D., and Britton W.J. Structural deficiencies in granuloma formation in TNF gene-targeted mice underlie the heightened susceptibility to aerosol Mycobacterium tuberculosis infection, which is not compensated for by lymphotoxin. J. Immunol. 162 (1999) 3504-3511
37. Algood H.M., Chan J., and Flynn J.L. Chemokines and tuberculosis. Cytokine Growth Factor Rev. 14 (2003) 467-477
38. Kaufmann S.H. How can immunology contribute to the control of tuberculosis?. Nat Rev Immunol 1 (2001) 20-30
39. Algood H.M., Lin P.L., Yankura D., Jones A., Chan J., and Flynn J.L. TNF influences chemokine expression of macrophages in vitro and that of CD11b+ cells in vivo during Mycobacterium tuberculosis infection. J. Immunol. 172 (2004) 6846-6857
40. Seiler P., Aichele P., Bandermann S., Hauser A.E., Lu B., Gerard N.P., Gerard C., Ehlers S., Mollenkopf H.J., and Kaufmann S.H. Early granuloma formation after aerosol Mycobacterium tuberculosis infection is regulated by neutrophils via CXCR3-signaling chemokines. Eur. J. Immunol. 33 (2003) 2676-2686
41. Peters W., Scott H.M., Chambers H.F., Flynn J.L., Charo I.F., and Ernst J.D. Chemokine receptor 2 serves an early and essential role in resistance to Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 7958-7963
42. Scott H.M., and Flynn J.L. Mycobacterium tuberculosis in chemokine receptor 2-deficient mice: influence of dose on disease progression. Infect. Immun. 70 (2002) 5946-5954
43. Algood H.M., and Flynn J.L. CCR5-deficient mice control Mycobacterium tuberculosis infection despite increased pulmonary lymphocytic infiltration. J. Immunol. 173 (2004) 3287-3296
44. Rutledge B.J., Rayburn H., Rosenberg R., North R.J., Gladue R.P., Corless C.L., and Rollins B.J. High level monocyte chemoattractant protein-1 expression in transgenic mice increases their susceptibility to intracellular pathogens. J. Immunol. 155 (1995) 4838-4843
45. Chensue S.W., Warmington K.S., Allenspach E.J., Lu B., Gerard C., Kunkel S.L., and Lukacs N.W. Differential expression and cross-regulatory function of RANTES during mycobacterial (type 1) and schistosomal (type 2) antigen-elicited granulomatous inflammation. J. Immunol. 163 (1999) 165-173
46. Kipnis A., Basaraba R.J., Orme I.M., and Cooper A.M. Role of chemokine ligand 2 in the protective response to early murine pulmonary tuberculosis. Immunology 109 (2003) 547-551
47. Martinez de la Torre Y., Locati M., Buracchi C., Dupor J., Cook D.N., Bonecchi R., Nebuloni M., Rukavina D., Vago L., Vecchi A., Lira S.A., and Mantovani A. Increased inflammation in mice deficient for the chemokine decoy receptor D6. Eur. J. Immunol. 35 (2005) 1342-1346
48. Nibbs R.J., Gilchrist D.S., King V., Ferra A., Forrow S., Hunter K.D., and Graham G.J. The atypical chemokine receptor D6 suppresses the development of chemically induced skin tumors. J. Clin. Invest. 117 (2007) 1884-1892
49. Di Liberto D., Locati M., Caccamo N., Vecchi A., Meraviglia S., Salerno A., Sireci G., Nebuloni M., Caceres N., Cardona P.J., Dieli F., and Mantovani A. Role of the chemokine decoy receptor D6 in balancing inflammation, immune activation, and antimicrobial resistance in Mycobacterium tuberculosis infection. J. Exp. Med. 205 (2008) 2075-2084