Chemokine decoy receptor D6 plays a negative role in human breast cancer

Molecular Cancer Research

Volumn 6, Issue 8, 2008, Pages 1276-1288

  Wu, Feng Ying ^a   Ou, Zhou Luo ^a   Feng, Lan Yun ^a   Luo, Jian Min ^a   Wang, Lei Ping ^a   Shen, Zhen Zhou ^a   Shao, Zhi Min ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CHEMOKINE; BINDING PROTEIN; CHEMOKINE BINDING PROTEIN D6; GAMMA INTERFERON; INTERLEUKIN 1BETA; MACROPHAGE DERIVED CHEMOKINE; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 4; RANTES; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CHEMOKINE; CHEMOKINE RECEPTOR CCR10; CHEMOKINE RECEPTOR D6; COMPLEMENTARY DNA; MESSENGER RNA;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER GROWTH; CANCER INVASION; CANCER SURVIVAL; CAPILLARY DENSITY; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; LYMPH NODE METASTASIS; MACROPHAGE MIGRATION; MAJOR CLINICAL STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; TUMOR ASSOCIATED LEUKOCYTE; ANIMAL; BREAST TUMOR; CANCER TRANSPLANTATION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MIDDLE AGED; MORTALITY; MOUSE; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; SURVIVAL RATE; TUMOR CELL LINE; VASCULARIZATION;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMOKINES; DNA, COMPLEMENTARY; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERLEUKIN-1BETA; LYMPHATIC METASTASIS; MICE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; RECEPTORS, CCR10; RNA, MESSENGER; SURVIVAL RATE; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 52449108571     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-07-2108     Document Type: Article

References (52)

1. Baggiolini M. Chemokines and leukocyte traffic. Nature 1998;392:565-8.
2. Zlotnik A, Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity 2000;12:121-7.
3. Sallusto F, Mackay CR, Lanzavecchia A. The role of chemokine receptors in primary, effector, and memory immune responses. Annu Rev Immunol 2000;18:593-620.
4. Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001;410:50-6.
5. Balkwill F. Cancer and the chemokine network. Nat Rev Cancer 2004;4:540-50.
6. Rollins BJ. Inflammatory chemokines in cancer growth and progression. Eur J Cancer 2006;42:760-7.
7. Zlotnik A. Chemokines and cancer. Int J Cancer 2006;119:2026-9.
8. Balkwill F. Chemokine biology in cancer. Semin Immunol 2003;15:49-55.
9. Horuk R, Chitnis CE, Darbonne WC, et al. A receptor for the malarial parasite Plasmodium vivax: the erythrocyte chemokine receptor. Science 1993;261:1182-4.
10. Bonini JA, Martin SK, Dralyuk F, Roe MW, Philipson LH, Steiner DF. Cloning, expression, and chromosomal mapping of a novel human CC-chemokine receptor (CCR10) that displays high-affinity binding for MCP-1 and MCP-3. DNA Cell Biol 1997;16:1249-56.
11. Nibbs RJ, Wylie SM, Yang J, Landau NR, Graham GJ. Cloning and characterization of a novel promiscuous human β-chemokine receptor D6. J Biol Chem 1997;272:32078-83.
12. Gosling J, Dairaghi DJ, Wang Y, et al. Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK. J Immunol 2000;164:2851-6.
13. Mantovani A, Bonecchi R, Locati M. Tuning inflammation and immunity by chemokine sequestration: decoys and more. Nat Rev Immunol 2006;6:907-18.
14. Comerford I, Litchfield W, Harata-Lee Y, Nibbs RJ, McColl SR. Regulation of chemotactic networks by "atypical" receptors. BioEssays 2007;29:237-47.
15. Lentsch AB. The Duffy antigen/receptor for chemokines (DARC) and prostate cancer. A role as clear as black and white? FASEB J 2002;16:1093-5.
16. Shen H, Schuster R, Stringer KF, Waltz SE, Lentsch AB. The Duffy antigen/ receptor for chemokines (DARC) regulates prostate tumor growth. FASEB J 2006;20:59-64.
17. Bandyopadhyay S, Zhan R, Chaudhuri A, et al. Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression. Nat Med 2006;12:933-8.
18. Addison CL, Belperio JA, Burdick MD, Strieter RM. Overexpression of the Duffy antigen receptor for chemokines (DARC) by NSCLC tumor cells results in increased tumor necrosis. BMC Cancer 2004;4:28.
19. Wang J, Ou ZL, Hou YF, et al. Enhanced expression of Duffy antigen receptor for chemokines by breast cancer cells attenuates growth and metastasis potential. Oncogene 2006;25:7201-11.
20. Nibbs RJ, Kriehuber E, Ponath PD, et al. The β-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors. Am J Pathol 2001;158:867-77.
21. + T-cell large granular lymphocyte leukemia. Int J Cancer 2004;108:845-51.
22. Martinez de la Torre Y, Buracchi C, Borroni EM, et al. Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6. Proc Natl Acad Sci U S A 2007;104:2319-24.
23. Nibbs RJ, Gilchrist DS, King V, et al. The atypical chemokine receptor D6 suppresses the development of chemically induced skin tumors. J Clin Invest 2007;117:1884-92.
24. Hansell CA, Simpson CV, Nibbs RJ. Chemokine sequestration by atypical chemokine receptors. Biochem Soc Trans 2006;34:1009-13.
25. Li DQ, Hou YF, Wu J, et al. Gene expression profile analysis of an isogenic tumour metastasis model reveals a functional role for oncogene AF1Q in breast cancer metastasis. Eur J Cancer 2006;42:3274-86.
26. Li DQ, Wang L, Fei F, et al. Identification of breast cancer metastasis-associated proteins in an isogenic tumor metastasis model using two-dimensional gel electrophoresis and liquid chromatography-ion trap-mass spectrometry. Proteomics 2006;6:3352-68.
27. Mantovani A, Allavena P, Sozzani S, Vecchi A, Locati M, Sica A. Chemokines in the recruitment and shaping of the leukocyte infiltrate of tumors. Semin Cancer Biol 2004;14:155-60.
28. Fra AM, Locati M, Otero K, et al. Cutting edge: scavenging of inflammatory CC chemokines by the promiscuous putatively silent chemokine receptor D6. J Immunol 2003;170:2279-82.
29. Locati M, Torre YM, Galliera E, et al. Silent chemoattractant receptors: D6 as a decoy and scavenger receptor for inflammatory CC chemokines. Cytokine Growth Factor Rev 2005;16:679-86.
30. Graham GJ, McKimmie CS. Chemokine scavenging by D6: a movable feast? Trends Immunol 2006;27:381-6.
31. Bonecchi R, Locati M, Galliera E, et al. Differential recognition and scavenging of native and truncated macrophage-derived chemokine (macrophage-derived chemokine/CC chemokine ligand 22) by the D6 decoy receptor. J Immunol 2004;172:4972-6.
32. Weber M, Blair E, Simpson CV, et al. The chemokine receptor D6 constitutively traffics to and from the cell surface to internalize and degrade chemokines. Mol Biol Cell 2004;15:2492-508.
33. Galliera E, Jala VR, Trent JO, et al. β-Arrestin-dependent constitutive internalization of the human chemokine decoy receptor D6. J Biol Chem 2004;279:25590-7.
34. Jamieson T, Cook DN, Nibbs RJ, et al. The chemokine receptor D6 limits the inflammatory response in vivo. Nat Immunol 2005;6:403-11.
35. Martinez de la Torre Y, Locati M, Buracchi C, et al. Increased inflammation in mice deficient for the chemokine decoy receptor D6. Eur J Immunol 2005;35:1342-6.
36. Whitehead GS, Wang T, DeGraff LM, et al. The chemokine receptor D6 has opposing effects on allergic inflammation and airway reactivity. Am J Respir Crit Care Med 2007;175:243-9.
37. Borroni EM, Buracchi C, de la Torre YM, et al. The chemoattractant decoy receptor D6 as a negative regulator of inflammatory responses. Biochem Soc Trans 2006;34:1014-7.
38. Ben-Baruch A. The multifaceted roles of chemokines in malignancy. Cancer Metastasis Rev 2006;25:357-71.
39. Kulbe H, Levinson NR, Balkwill F, Wilson JL. The chemokine network in cancer-much more than directing cell movement. Int J Dev Biol 2004;48:489-96.
40. Bieche I, Lerebours F, Tozlu S, Espie M, Marty M, Lidereau R. Molecular profiling of inflammatory breast cancer: identification of a poor-prognosis gene expression signature. Clin Cancer Res 2004;10:6789-95.
41. Luboshits G, Shina S, Kaplan O, et al. Elevated expression of the CC chemokine regulated on activation, normal T cell expressed and secreted (RANTES) in advanced breast carcinoma. Cancer Res 1999;59:4681-7.
42. Niwa Y, Akamatsu H, Niwa H, Sumi H, Ozaki Y, Abe A. Correlation of tissue and plasma RANTES levels with disease course in patients with breast or cervical cancer. Clin Cancer Res 2001;7:285-9.
43. Ueno T, Toi M, Saji H, et al. Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer. Clin Cancer Res 2000;6:3282-9.
44. Robinson SC, Scott KA, Wilson JL, Thompson RG, Proudfoot AE, Balkwill FR. A chemokine receptor antagonist inhibits experimental breast tumor growth. Cancer Res 2003;63:8360-5.
45. Salcedo R, Ponce ML, Young HA, et al. Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression. Blood 2000;96:34-40.
46. Stormes KA, Lemken CA, Lepre JV, Marinucci MN, Kurt RA. Inhibition of metastasis by inhibition of tumor-derived CCL5. Breast Cancer Res Treat 2005;89:209-12.
47. Azenshtein E, Luboshits G, Shina S, et al. The CC chemokine RANTES in breast carcinoma progression: regulation of expression and potential mechanisms of promalignant activity. Cancer Res 2002;62:1093-102.
48. Saji H, Koike M, Yamori T, et al. Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma. Cancer 2001;92:1085-91.
49. Leek RD, Harris AL. Tumor-associated macrophages in breast cancer. J Mammary Gland Biol Neoplasia 2002;7:177-89.
50. Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 2004;4:71-8.
51. Flanagan K, Kaufman HL. Chemokines and cancer. Cancer Invest 2002;20:825-34.
52. Vicari AP, Caux C. Chemokines in cancer. Cytokine Growth Factor Rev 2002;13:143-54.