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Volumn 16, Issue 4, 2009, Pages 204-215

Multigene classifiers, prognostic factors, and predictors of breast cancer clinical outcome

Author keywords

Breast cancer; Invasiveness signature; Mammaprint; Oncotype Dx; Rotterdam signature; Two gene expression ratio

Indexed keywords

BIOLOGICAL MARKER; CYCLOPHOSPHAMIDE; CYTOCHROME P450 2D6; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; FLUOROURACIL; FORMALDEHYDE; HOMEODOMAIN PROTEIN; INTERLEUKIN 17 RECEPTOR; KI 67 ANTIGEN; MESSENGER RNA; PACLITAXEL; PARAFFIN; RAS PROTEIN; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; TAMOXIFEN; TRANSCRIPTION FACTOR E2F;

EID: 68849107487     PISSN: 10724109     EISSN: 15334031     Source Type: Journal    
DOI: 10.1097/PAP.0b013e3181a9d4bf     Document Type: Review
Times cited : (58)

References (84)
  • 1
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature. 2000;406:747-752.
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 2
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van 't Veer LJ, Dai H, van de Vijver MJ, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 2002;415:530-536.
    • (2002) Nature , vol.415 , pp. 530-536
    • Van 't Veer, L.J.1    Dai, H.2    Van De Vijver, M.J.3
  • 5
    • 34249095430 scopus 로고    scopus 로고
    • New Generation of Molecular Prognostic and Predictive Tests for Breast Cancer
    • DOI 10.1053/j.seminoncol.2007.03.015, PII S0093775407000693
    • Pusztai L, Cristofanilli M, Paik S. New generation of molecular prognostic and predictive tests for breast cancer. Semin Oncol. 2007;34:S10-S16. (Pubitemid 46778751)
    • (2007) Seminars in Oncology , vol.34 , Issue.SUPPL. 3
    • Pusztai, L.1    Cristofanilli, M.2    Paik, S.3
  • 6
    • 45749157664 scopus 로고    scopus 로고
    • Commercialized multigene predictors of clinical outcome for breast cancer
    • DOI 10.1634/theoncologist.2007-0248
    • Ross JS, Hatzis C, Symmans WF, et al. Commercialized multigene predictors of clinical outcome for breast cancer. Oncologist. 2008;13:477-493. (Pubitemid 351872866)
    • (2008) Oncologist , vol.13 , Issue.5 , pp. 477-493
    • Ross, J.S.1    Hatzis, C.2    Symmans, W.F.3    Pusztai, L.4    Hortobagyi, G.N.5
  • 7
    • 60849097255 scopus 로고    scopus 로고
    • Gene-expression signatures in breast cancer
    • Sotiriou C, Pusztai L. Gene-expression signatures in breast cancer. N Engl J Med. 2009;360:790-800.
    • (2009) N Engl J Med , vol.360 , pp. 790-800
    • Sotiriou, C.1    Pusztai, L.2
  • 9
    • 33846784074 scopus 로고    scopus 로고
    • Microarrays in breast cancer research and clinical practice - The future lies ahead
    • Gruvberger-Saal SK, Cunliffe HE, Carr KM, et al. Microarrays in breast cancer research and clinical practice - the future lies ahead. Endocr Relat Cancer. 2006;13:1017-1031.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 1017-1031
    • Gruvberger-Saal, S.K.1    Cunliffe, H.E.2    Carr, K.M.3
  • 10
    • 34249822213 scopus 로고    scopus 로고
    • Standardizing slide-based assays in breast cancer: Hormone receptors, HER2, and sentinel lymph nodes
    • Ross JS, Symmans WF, Pusztai L, et al. Standardizing slide-based assays in breast cancer: hormone receptors, HER2, and sentinel lymph nodes. Clin Cancer Res. 2007;13:2831-2835.
    • (2007) Clin Cancer Res , vol.13 , pp. 2831-2835
    • Ross, J.S.1    Symmans, W.F.2    Pusztai, L.3
  • 12
    • 45749101123 scopus 로고    scopus 로고
    • Selection and optimization of a panel of early stage breast cancer prognostic molecular markers
    • Whitehead CM, Nelson R, Hudson P, et al. Selection and optimization of a panel of early stage breast cancer prognostic molecular markers. Mod Pathol. 2004;17:50A.
    • (2004) Mod Pathol , vol.17
    • Whitehead, C.M.1    Nelson, R.2    Hudson, P.3
  • 17
    • 20444500954 scopus 로고    scopus 로고
    • Technology insight: Application of molecular techniques to formalin-fixed paraffin-embedded tissues from breast cancer
    • DOI 10.1038/ncponc0171
    • Paik S, Kim CY, Song YK, et al. Technology insight: application of molecular techniques to formalin-fixed paraffin-embedded tissues from breast cancer. Nat Clin Pract Oncol. 2005;2:246-254. (Pubitemid 40812455)
    • (2005) Nature Clinical Practice Oncology , vol.2 , Issue.5 , pp. 246-254
    • Paik, S.1    Kim, C.-Y.2    Song, Y.-K.3    Kim, W.-S.4
  • 20
    • 33845502266 scopus 로고    scopus 로고
    • A genetic signature can predict prognosis and response to therapy in breast cancer: Oncotype DX
    • DOI 10.1586/14737159.6.6.803
    • Kaklamani V. A genetic signature can predict prognosis and response to therapy in breast cancer: Oncotype DX. Expert Rev Mol Diagn. 2006;6:803-809. (Pubitemid 44911030)
    • (2006) Expert Review of Molecular Diagnostics , vol.6 , Issue.6 , pp. 803-809
    • Kaklamani, V.1
  • 21
    • 34249887687 scopus 로고    scopus 로고
    • Analytical validation of the oncotype DX genomic diagnostic test for recurrence prognosis and therapeutic response prediction in node-negative, estrogen receptor-positive breast cancer
    • DOI 10.1373/clinchem.2006.076497
    • Cronin M, Sangli C, Liu ML, et al. Analytical validation of the Oncotype DX genomic diagnostic test for recurrence prognosis and therapeutic response prediction in node-negative, estrogen receptor-positive breast cancer. Clin Chem. 2007;53:1084-1091. (Pubitemid 46867525)
    • (2007) Clinical Chemistry , vol.53 , Issue.6 , pp. 1084-1091
    • Cronin, M.1    Sangli, C.2    Liu, M.-L.3    Pho, M.4    Dutta, D.5    Nguyen, A.6    Jeong, J.7    Wu, J.8    Langone, K.C.9    Watson, D.10
  • 22
    • 34447132081 scopus 로고    scopus 로고
    • Development and clinical utility of a 21-gene recurrence score prognostic assay in patients with early breast cancer treated with tamoxifen
    • DOI 10.1634/theoncologist.12-6-631
    • Paik S. Development and clinical utility of a 21-gene recurrence score prognostic assay in patients with early breast cancer treated with tamoxifen. Oncologist. 2007;12:631-635. (Pubitemid 47036199)
    • (2007) Oncologist , vol.12 , Issue.6 , pp. 631-635
    • Paik, S.1
  • 25
    • 33646255471 scopus 로고    scopus 로고
    • A two-gene expression ratio of homeobox 13 and interleukin-17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifen
    • Goetz MP, Suman VJ, Ingle JN, et al. A two-gene expression ratio of homeobox 13 and interleukin-17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifen. Clin Cancer Res. 2006;12:2080-2087.
    • (2006) Clin Cancer Res , vol.12 , pp. 2080-2087
    • Goetz, M.P.1    Suman, V.J.2    Ingle, J.N.3
  • 26
    • 35948942354 scopus 로고    scopus 로고
    • The prognostic biomarkers HOXB13, IL17BR, and CHDH are regulated by estrogen in breast cancer
    • Wang Z, Dahiya S, Provencher H, et al. The prognostic biomarkers HOXB13, IL17BR, and CHDH are regulated by estrogen in breast cancer. Clin Cancer Res. 2007;13: 6327-6334.
    • (2007) Clin Cancer Res , vol.13 , pp. 6327-6334
    • Wang, Z.1    Dahiya, S.2    Provencher, H.3
  • 27
    • 33847643776 scopus 로고    scopus 로고
    • Quantification of mRNA using real-time RT-PCR
    • Nolan T, Hands RE, Bustin SA. Quantification of mRNA using real-time RT-PCR. Nat Protoc. 2006;1:1559-1582.
    • (2006) Nat Protoc , vol.1 , pp. 1559-1582
    • Nolan, T.1    Hands, R.E.2    Bustin, S.A.3
  • 32
    • 1942533557 scopus 로고    scopus 로고
    • Molecular profiling of breast cancer: Clinical implications
    • DOI 10.1038/sj.bjc.6601667
    • Cleator S, Ashworth A. Molecular profiling of breast cancer: clinical implications. Br J Cancer. 2004;90:1120-1124. (Pubitemid 38496800)
    • (2004) British Journal of Cancer , vol.90 , Issue.6 , pp. 1120-1124
    • Cleator, S.1    Ashworth, A.2
  • 34
    • 33748693297 scopus 로고    scopus 로고
    • TRANSBIG Consortium. Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer
    • Buyse M, Loi S, van't Veer L, et al; TRANSBIG Consortium. Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer. J Natl Cancer Inst. 2006;98:1183-1189.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 1183-1189
    • Buyse, M.1    Loi, S.2    Van't Veer, L.3
  • 35
    • 34247544331 scopus 로고    scopus 로고
    • Gene expression signatures to predict the development of metastasis in breast cancer
    • Nuyten DS, van de Vijver MJ. Gene expression signatures to predict the development of metastasis in breast cancer. Breast Dis. 2006-2007;26:149-156. (Pubitemid 46647420)
    • (2006) Breast Disease , vol.26 , Issue.1 , pp. 149-156
    • Nuyten, D.S.A.1    Van De Vijver, M.J.2
  • 39
    • 34250652449 scopus 로고    scopus 로고
    • TRANSBIG Consortium. Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series
    • Desmedt C, Piette F, Loi S, et al; TRANSBIG Consortium. Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series. Clin Cancer Res. 2007;13:3207-3214.
    • (2007) Clin Cancer Res , vol.13 , pp. 3207-3214
    • Desmedt, C.1    Piette, F.2    Loi, S.3
  • 43
    • 33645221975 scopus 로고    scopus 로고
    • Gene expression patterns for doxorubicin (Adriamycin) and cyclophosphamide (Cytoxan) (AC) response and resistance
    • Cleator S, Tsimelzon A, Ashworth A, et al. Gene expression patterns for doxorubicin (Adriamycin) and cyclophosphamide (Cytoxan) (AC) response and resistance. Breast Cancer Res Treat. 2006;95:229-233.
    • (2006) Breast Cancer Res Treat , vol.95 , pp. 229-233
    • Cleator, S.1    Tsimelzon, A.2    Ashworth, A.3
  • 46
    • 25444466435 scopus 로고    scopus 로고
    • Microtubule associated protein (MAP)-Tau: A novel mediator of paclitaxel sensitivity in vitro and in vivo
    • Wagner P, Wang B, Clark E, et al. Microtubule associated protein (MAP)-Tau: a novel mediator of paclitaxel sensitivity in vitro and in vivo. Cell Cycle. 2005;4:1149-1152. (Pubitemid 41365380)
    • (2005) Cell Cycle , vol.4 , Issue.9 , pp. 1149-1152
    • Wagner, P.1    Wang, B.2    Clark, E.3    Lee, H.4    Rouzier, R.5    Pusztai, L.6
  • 49
    • 34547098349 scopus 로고    scopus 로고
    • Thirty-gene pharmacogenomic test correlates with residual cancer burden after preoperative chemotherapy for breast cancer
    • Peintinger F, Anderson K, Mazouni C, et al. Thirty-gene pharmacogenomic test correlates with residual cancer burden after preoperative chemotherapy for breast cancer. Clin Cancer Res. 2007;13:4078-4082.
    • (2007) Clin Cancer Res , vol.13 , pp. 4078-4082
    • Peintinger, F.1    Anderson, K.2    Mazouni, C.3
  • 51
    • 33748491517 scopus 로고    scopus 로고
    • The MicroArray Quality Control (MAQC) project shows inter- And intraplatform reproducibility of gene expression measurements
    • DOI 10.1038/nbt1239, PII NBT1239
    • Shi L, Reid LH, Jones WD, et al. The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nat Biotechnol. 2006;24:1151-1161. (Pubitemid 44359727)
    • (2006) Nature Biotechnology , vol.24 , Issue.9 , pp. 1151-1161
    • Shi, L.1
  • 60
    • 33845438621 scopus 로고    scopus 로고
    • Are clusters found in one dataset present in another dataset?
    • Kapp AV, Tibshirani R. Are clusters found in one dataset present in another dataset? Biostatistics. 2007;8:9-31.
    • (2007) Biostatistics , vol.8 , pp. 9-31
    • Kapp, A.V.1    Tibshirani, R.2
  • 61
    • 62449131093 scopus 로고    scopus 로고
    • Supervised risk predictor of breast cancer based on intrinsic subtypes
    • Parker JS, Mullins M, Cheang MC, et al. Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol. 2009;27:1160-1167.
    • (2009) J Clin Oncol , vol.27 , pp. 1160-1167
    • Parker, J.S.1    Mullins, M.2    Cheang, M.C.3
  • 62
    • 41649102048 scopus 로고    scopus 로고
    • Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer
    • Liedtke C, Mazouni C, Hess KR, et al. Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer. J Clin Oncol. 2008;26:1275-1281.
    • (2008) J Clin Oncol , vol.26 , pp. 1275-1281
    • Liedtke, C.1    Mazouni, C.2    Hess, K.R.3
  • 63
    • 3142630226 scopus 로고    scopus 로고
    • Prognostic value of proliferation in invasive breast cancer: A review
    • DOI 10.1136/jcp.2003.010777
    • van Diest PJ, van der Wall E, Baak JP. Prognostic value of proliferation in invasive breast cancer: a review. J Clin Pathol. 2004;57:675-681. (Pubitemid 38901478)
    • (2004) Journal of Clinical Pathology , vol.57 , Issue.7 , pp. 675-681
    • Van Diest, P.J.1    Van Der Wall, E.2    Baak, J.P.A.3
  • 66
    • 33745641883 scopus 로고    scopus 로고
    • Uses and abuses of tumor markers in the diagnosis, monitoring, and treatment of primary and metastatic breast cancer
    • DOI 10.1634/theoncologist.11-6-541
    • Henry NL, Hayes DF. Uses and abuses of tumor markers in the diagnosis, monitoring, and treatment of primary and metastatic breast cancer. Oncologist. 2006;11:541-552. (Pubitemid 43967610)
    • (2006) Oncologist , vol.11 , Issue.6 , pp. 541-552
    • Henry, N.L.1    Hayes, D.F.2
  • 68
    • 41649086322 scopus 로고    scopus 로고
    • Prospective multicenter study of the impact of the 21-gene recurrence score assay on patient satisfaction, anxiety and decisional conflict for adjuvant breast cancer treatment selection
    • [abstract]
    • Mumby PB, Lo SS, Norton J, et al. Prospective multicenter study of the impact of the 21-gene recurrence score assay on patient satisfaction, anxiety and decisional conflict for adjuvant breast cancer treatment selection [abstract]. Breast Cancer Res treat. 2007;106(suppl 1):S73.
    • (2007) Breast Cancer Res Treat , vol.106 , Issue.SUPPL. 1
    • Mumby, P.B.1    Lo, S.S.2    Norton, J.3
  • 70
    • 40449114164 scopus 로고    scopus 로고
    • Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal, node-positive, ER-positive breast cancer
    • Albain K, Barlow W, Shak S, et al. Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal, node-positive, ER-positive breast cancer. Breast Cancer Res Treat. 2008;84:S8814.
    • (2008) Breast Cancer Res Treat , vol.84
    • Albain, K.1    Barlow, W.2    Shak, S.3
  • 71
    • 39349113685 scopus 로고    scopus 로고
    • Prospective multicenter study of the impact of the 21-gene recurrence score (RS) assay on medical oncologist (MO) and patient (pt) adjuvant breast cancer (BC) treatment selection
    • Lo SS, Norton J, Mumby PB, et al. Prospective multicenter study of the impact of the 21-gene recurrence score (RS) assay on medical oncologist (MO) and patient (pt) adjuvant breast cancer (BC) treatment selection. J Clin Oncol (2007 ASCO Annual Meeting Proceedings Part I). 2007; 25(18S):577.
    • (2007) J Clin Oncol (2007 ASCO Annual Meeting Proceedings Part I) , vol.25 , Issue.18 , pp. 577
    • Lo, S.S.1    Norton, J.2    Mumby, P.B.3
  • 72
    • 33750895236 scopus 로고    scopus 로고
    • TAILORx: Trial Assigning Individualized Options for Treatment (Rx)
    • Sparano JA. TAILORx: trial assigning individualized options for treatment (Rx). Clin Breast Cancer. 2006;7:347-350. (Pubitemid 44717771)
    • (2006) Clinical Breast Cancer , vol.7 , Issue.4 , pp. 347-350
    • Sparano, J.A.1
  • 73
    • 1642349616 scopus 로고    scopus 로고
    • Gene Expression Tests Foretell Breast Cancer's Future
    • DOI 10.1126/science.303.5665.1754
    • Garber K. Gene expression tests foretell breast cancer's future. Science. 2007;303:1754-1755. (Pubitemid 38374842)
    • (2004) Science , vol.303 , Issue.5665 , pp. 1754-1755
    • Garber, K.1
  • 75
    • 34347388416 scopus 로고    scopus 로고
    • Agreement in breast cancer classification between microarray and quantitative reverse transcription PCR from fresh-frozen and formalin-fixed, paraffin-embedded tissues
    • DOI 10.1373/clinchem.2006.083725
    • Mullins M, Perreard L, Quackenbush JF, et al. Agreement in breast cancer classification between microarray and quantitative reverse transcription PCR from fresh-frozen and formalin-fixed, paraffin-embedded tissues. Clin Chem. 2007;53: 1273-1279. (Pubitemid 47020983)
    • (2007) Clinical Chemistry , vol.53 , Issue.7 , pp. 1273-1279
    • Mullins, M.1    Perreard, L.2    Quackenbush, J.F.3    Gauthier, N.4    Bayer, S.5    Ellis, M.6    Parker, J.7    Perou, C.M.8    Szabo, A.9    Bernard, P.S.10
  • 77
    • 33750601244 scopus 로고    scopus 로고
    • TRANSBIG consortium. Gene signature evaluation as a prognostic tool: Challenges in the design of the MINDACT trial
    • Bogaerts J, Cardoso F, Buyse M, et al; TRANSBIG consortium. Gene signature evaluation as a prognostic tool: challenges in the design of the MINDACT trial. Nat Clin Pract Oncol. 2006;3:540-551.
    • (2006) Nat Clin Pract Oncol , vol.3 , pp. 540-551
    • Bogaerts, J.1    Cardoso, F.2    Buyse, M.3
  • 78
    • 36849069347 scopus 로고    scopus 로고
    • American Society of Clinical Oncology 2007 Update of Recommendations for the Use of Tumor Markers in Breast Cancer
    • Harris L, Fritsche H, Mennel R, et al. American Society of Clinical Oncology 2007 Update of Recommendations for the Use of Tumor Markers in Breast Cancer. J Clin Oncol. 2007;25:118-145.
    • J Clin Oncol , vol.2007 , Issue.25 , pp. 118-145
    • Harris, L.1    Fritsche, H.2    Mennel, R.3
  • 79
    • 34147164024 scopus 로고    scopus 로고
    • Is molecular profiling ready for use in clinical decision making?
    • Ioannidis JP. Is molecular profiling ready for use in clinical decision making?. Oncologist. 2007;12:301-311.
    • (2007) Oncologist , vol.12 , pp. 301-311
    • Ioannidis, J.P.1
  • 80
    • 33947196825 scopus 로고    scopus 로고
    • Impact of a 21-gene RT-PCR assay on treatment decisions in early-stage breast cancer: An economic analysis based on prognostic and predictive validation studies
    • Lyman GH, Cosler LE, Kuderer NM, et al. Impact of a 21-gene RT-PCR assay on treatment decisions in early-stage breast cancer: an economic analysis based on prognostic and predictive validation studies. Cancer. 2007;109:1011-1018.
    • (2007) Cancer , vol.109 , pp. 1011-1018
    • Lyman, G.H.1    Cosler, L.E.2    Kuderer, N.M.3
  • 82
    • 33644639136 scopus 로고    scopus 로고
    • Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes
    • Goetz MP, Rae JM, Suman VJ, et al. Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes. J Clin Oncol. 2005;23:9312-9318.
    • (2005) J Clin Oncol , vol.23 , pp. 9312-9318
    • Goetz, M.P.1    Rae, J.M.2    Suman, V.J.3
  • 83
    • 19944434201 scopus 로고    scopus 로고
    • CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment
    • Jin Y, Desta Z, Stearns V, et al. CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment. J Natl Cancer Inst. 2005; 97:30-39.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 30-39
    • Jin, Y.1    Desta, Z.2    Stearns, V.3
  • 84
    • 33847034287 scopus 로고    scopus 로고
    • The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen
    • Goetz MP, Knox SK, Suman VJ, et al. The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen. Breast Cancer Res Treat. 2007;101:113-121.
    • (2007) Breast Cancer Res Treat , vol.101 , pp. 113-121
    • Goetz, M.P.1    Knox, S.K.2    Suman, V.J.3


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