Methods for gene expression profiling in clinical trials of adjuvant breast cancer therapy

Clinical Cancer Research

Volumn 12, Issue 3 II, 2006, Pages

  Paik, Soonmyung ^a   Brown, Myles ^b   Ingle, James ^b   Dowsett, Mitch ^b   Johnston, Stephen ^b   Buzdar, Aman ^b   Winer, Eric ^b  

^a NSABP Foundation Inc   (United States)

^b Four Allegheny Center ^*

Author keywords

[No Author keywords available]

Indexed keywords

ANASTROZOLE; BEVACIZUMAB; MESSENGER RNA; PLACEBO; TAMOXIFEN; TRASTUZUMAB;

ADJUVANT CHEMOTHERAPY; BREAST CANCER; CANCER RISK; CLINICAL TRIAL; CONFERENCE PAPER; DNA MICROARRAY; DNA SYNTHESIS; FOLLOW UP; GENE EXPRESSION; HUMAN; PRIORITY JOURNAL; PROGNOSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; TREATMENT FAILURE;

ANTINEOPLASTIC AGENTS, HORMONAL; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; CLINICAL TRIALS; FEMALE; FORMALDEHYDE; GENE EXPRESSION PROFILING; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARAFFIN EMBEDDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TISSUE FIXATION;

EID: 32944463609     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-05-2296     Document Type: Conference Paper

References (5)

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2. Cronin M, Pho M, Dutta D, et al. Measurement of gene expression in archival paraffin-embedded tissues: development and performance of a 92-gene reverse transcriptase-polymerase chain reaction assay. Am J Pathol 2004;164:35-42.
3. Paik S, Shak S, Tang G, et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 2004;351:2817-26.
4. Fisher B, Jeong JH, Bryant J, et al. Treatment of lymph-node-negative, oestrogen-receptor-positive breast cancer: long-term findings from National Surgical Adjuvant Breast and Bowel Project randomised clinical trials. Lancet 2004;364:858-68.
5. Bibikova M, Talantov D, Chudin E, et al. Quantitative gene expression profiling in formalin-fixed, paraffin-embedded tissues using universal bead arrays. Am J Pathol 2004;165:1799-807.