Evidence for genetic association and interaction between the TYK2 and IRF5 genes in systemic lupus erythematosus

Journal of Rheumatology

Volumn 36, Issue 8, 2009, Pages 1631-1638

  Hellquist, Anna ^a   Järvinen, Tiina M ^a,b,c,d   Koskenmies, Sari ^b,c   Zucchelli, Marco ^a   Orsmark Pietras, Christina ^a   Berglind, Linda ^e   Panelius, Jaana ^b   Hasan, Taina ^f   Julkunen, Heikki ^b   D'Amato, Mauro ^a   Saarialho Kere, Ulpu ^b   Kere, Juha ^a,c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d Helsinki Biomedical Graduate School   (Finland)

^e KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^f TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Disease susceptibility; Genetic association; Genetic interaction; IRF5; Systemic lupus erythematosus; TYK2

Indexed keywords

INTERFERON;

ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; AUTOIMMUNE DISEASE; CHILD; CONTROLLED STUDY; CTLA4 GENE; EPISTASIS; FCGR2A GENE; FEMALE; FINLAND; GENE; GENE FREQUENCY; GENE INTERACTION; GENE ISOLATION; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; IRF5 GENE; MAJOR CLINICAL STUDY; MALE; NOD2 GENE; PDCD1 GENE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS; TYK2 GENE;

ADOLESCENT; ADULT; AGED; ANTIGENS, CD; APOPTOSIS REGULATORY PROTEINS; CHILD; EPISTASIS, GENETIC; FEMALE; FINLAND; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INTERFERON REGULATORY FACTORS; INTERFERON TYPE I; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; NOD2 SIGNALING ADAPTOR PROTEIN; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, IGG; RISK FACTORS; TYK2 KINASE; YOUNG ADULT;

EID: 68849087177     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: 10.3899/jrheum.081160     Document Type: Article

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