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Volumn 422, Issue 1, 2009, Pages 83-90

NCU-G1 is a highly glycosylated integral membrane protein of the lysosome

Author keywords

Lysosomal sorting; Lysosome; Membrane; NCU G1; Tyrosine based signal

Indexed keywords

ALANINE RESIDUES; AMINO ACID PROTEINS; AMINO ACID SEQUENCE; BIOINFORMATICS ANALYSIS; C-TERMINAL TAIL; GENBANK; GLYCOSYLATED; HELA CELL; HT-1080; HUMAN PLACENTA; INTEGRAL MEMBRANE PROTEINS; LYSOSOMAL MEMBRANES; LYSOSOMAL SORTING; LYSOSOME; MARKER LAMPS; MEMBRANE PROTEINS; MOUSE LIVER; N-GLYCOSIDASE; NCU-G1; PROTEIN SIZE; PROTEOMIC STUDIES; SUBCELLULAR FRACTIONATION; TRANS-MEMBRANE PROTEINS; TYROSINE RESIDUES; TYROSINE-BASED SIGNAL; WILD TYPES;

EID: 68749095380     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20090567     Document Type: Article
Times cited : (19)

References (48)
  • 2
    • 68749087438 scopus 로고    scopus 로고
    • Saftig, P. (2005) Lysosomes, Landes Bioscience/Eurekah.com Inc., New York
    • Saftig, P. (2005) Lysosomes, Landes Bioscience/Eurekah.com Inc., New York
  • 3
    • 43149104361 scopus 로고    scopus 로고
    • Sagne, C. and Gasnier, B. (2008) Molecular physiology and pathophysiology of lysosomal membrane transporters, J. Inherit. Metab. Dis., doi: 10.1007/s10545-008-0879-9
    • Sagne, C. and Gasnier, B. (2008) Molecular physiology and pathophysiology of lysosomal membrane transporters, J. Inherit. Metab. Dis., doi: 10.1007/s10545-008-0879-9
  • 4
    • 62949241063 scopus 로고    scopus 로고
    • Molecular and cellular basis of lysosomal transmembrane protein dysfunction
    • Ruivo, R., Anne, C., Sagne, C. and Gasnier, B. (2008) Molecular and cellular basis of lysosomal transmembrane protein dysfunction. Biochim. Biophys. Acta 1793, 636-649
    • (2008) Biochim. Biophys. Acta , vol.1793 , pp. 636-649
    • Ruivo, R.1    Anne, C.2    Sagne, C.3    Gasnier, B.4
  • 9
    • 0033760264 scopus 로고    scopus 로고
    • Cloning of the gene encoding a novel integral membrane protein, mucolipidin and identification of the two major founder mutations causing mucolipidosis type IV
    • Bassi, M. T., Manzoni, M., Monti, E., Pizzo, M. T., Ballabio, A. and Borsani, G. (2000) Cloning of the gene encoding a novel integral membrane protein, mucolipidin and identification of the two major founder mutations causing mucolipidosis type IV. Am. J. Hum. Genet. 67, 1110-1120
    • (2000) Am. J. Hum. Genet , vol.67 , pp. 1110-1120
    • Bassi, M.T.1    Manzoni, M.2    Monti, E.3    Pizzo, M.T.4    Ballabio, A.5    Borsani, G.6
  • 14
    • 0038795645 scopus 로고    scopus 로고
    • Signals for sorting of transmembrane proteins to endosomes and lysosomes
    • Bonifacino, J. S. and Traub, L. M. (2003) Signals for sorting of transmembrane proteins to endosomes and lysosomes. Ann. Rev. Biochem. 72, 395-447
    • (2003) Ann. Rev. Biochem , vol.72 , pp. 395-447
    • Bonifacino, J.S.1    Traub, L.M.2
  • 16
  • 17
    • 0029670902 scopus 로고    scopus 로고
    • The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane
    • Rohrer, J., Schweizer, A., Russell, D. and Kornfeld, S. (1996) The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane. J. Cell Biol. 132, 565-576
    • (1996) J. Cell Biol , vol.132 , pp. 565-576
    • Rohrer, J.1    Schweizer, A.2    Russell, D.3    Kornfeld, S.4
  • 18
    • 33645572770 scopus 로고    scopus 로고
    • Intracellular localization of p40, a protein identified in a preparation of lysosomal membranes
    • Boonen, M., Hamer, I., Boussac, M., Delsaute, A. F., Flamion, B., Garin, J. and Jadot, M. (2006) Intracellular localization of p40, a protein identified in a preparation of lysosomal membranes. Biochem. J. 395, 39-47
    • (2006) Biochem. J , vol.395 , pp. 39-47
    • Boonen, M.1    Hamer, I.2    Boussac, M.3    Delsaute, A.F.4    Flamion, B.5    Garin, J.6    Jadot, M.7
  • 22
    • 33749024739 scopus 로고    scopus 로고
    • Identification of the gene encoding the enzyme deficient in mucopolysaccharidosis IIIC (Sanfilippo disease type C)
    • Fan, X., Zhang, H., Zhang, S., Bagshaw, R. D., Tropak, M. B., Callahan, J. W. and Mahuran, D. J. (2006) Identification of the gene encoding the enzyme deficient in mucopolysaccharidosis IIIC (Sanfilippo disease type C). Am. J. Hum. Genet. 79, 738-744
    • (2006) Am. J. Hum. Genet , vol.79 , pp. 738-744
    • Fan, X.1    Zhang, H.2    Zhang, S.3    Bagshaw, R.D.4    Tropak, M.B.5    Callahan, J.W.6    Mahuran, D.J.7
  • 24
    • 0028834530 scopus 로고
    • The two mannose 6-phosphate receptors transport distinct complements of lysosomal proteins
    • Pohlmann, R., Boeker, M. W. and von Figura, K. (1995) The two mannose 6-phosphate receptors transport distinct complements of lysosomal proteins. J. Biol. Chem. 270, 27311-27318
    • (1995) J. Biol. Chem , vol.270 , pp. 27311-27318
    • Pohlmann, R.1    Boeker, M.W.2    von Figura, K.3
  • 25
    • 60349128150 scopus 로고    scopus 로고
    • Molecular characterization and gene disruption of mouse lysosomal putative serine carboxypeptidase 1
    • Kollmann, K., Damme, M., Deuschl, F., Kahle, J., D'Hooge, R., Lullmann-Rauch, R. and Lubke, T. (2009) Molecular characterization and gene disruption of mouse lysosomal putative serine carboxypeptidase 1. FEBS J. 276, 1356-1369
    • (2009) FEBS J , vol.276 , pp. 1356-1369
    • Kollmann, K.1    Damme, M.2    Deuschl, F.3    Kahle, J.4    D'Hooge, R.5    Lullmann-Rauch, R.6    Lubke, T.7
  • 27
    • 0035036072 scopus 로고    scopus 로고
    • Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency
    • Lubke, T., Marquardt, T., Etzioni, A., Hartmann, E., von Figura, K. and Korner, C. (2001) Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency. Nat. Genet. 28, 73-76
    • (2001) Nat. Genet , vol.28 , pp. 73-76
    • Lubke, T.1    Marquardt, T.2    Etzioni, A.3    Hartmann, E.4    von Figura, K.5    Korner, C.6
  • 28
    • 33749322938 scopus 로고    scopus 로고
    • Molecular characterization of the hypothetical 66.3 kDa protein in mouse: Lysosomal targeting, glycosylation, processing and tissue distribution
    • Deuschl, F., Kollmann, K., von Figura, K. and Lubke, T. (2006) Molecular characterization of the hypothetical 66.3 kDa protein in mouse: lysosomal targeting, glycosylation, processing and tissue distribution. FEBS Lett. 580, 5747-5752
    • (2006) FEBS Lett , vol.580 , pp. 5747-5752
    • Deuschl, F.1    Kollmann, K.2    von Figura, K.3    Lubke, T.4
  • 29
    • 77049229661 scopus 로고
    • Tissue fraction studies. 6. Intracellular distribution patterns of enzymes in rat liver tissue
    • de Duve, C., Pressman, B., Gianetto, R., Wattiaux, R. and Appelmans, F. (1955) Tissue fraction studies. 6. Intracellular distribution patterns of enzymes in rat liver tissue. Biochem. J. 60, 604-617
    • (1955) Biochem. J , vol.60 , pp. 604-617
    • de Duve, C.1    Pressman, B.2    Gianetto, R.3    Wattiaux, R.4    Appelmans, F.5
  • 30
    • 33749354488 scopus 로고
    • Effect of the injection of Triton WR 1339 on the hepatic lysosomes of the rat.]
    • Wattiaux, R., Wibo, M. and Baudhuin, P. (1963) [Effect of the injection of Triton WR 1339 on the hepatic lysosomes of the rat.] Arch. Int. Physiol. Biochim. 71, 140-142
    • (1963) Arch. Int. Physiol. Biochim , vol.71 , pp. 140-142
    • Wattiaux, R.1    Wibo, M.2    Baudhuin, P.3
  • 31
    • 0027330919 scopus 로고
    • Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor gene in mice results in misrouting of lysosomal proteins
    • Koster, A., Saftig, P., Matzner, U., von Figura, K., Peters, C. and Pohlmann, R. (1993) Targeted disruption of the M(r) 46,000 mannose 6-phosphate receptor gene in mice results in misrouting of lysosomal proteins. EMBO J. 12, 5219-5223
    • (1993) EMBO J , vol.12 , pp. 5219-5223
    • Koster, A.1    Saftig, P.2    Matzner, U.3    von Figura, K.4    Peters, C.5    Pohlmann, R.6
  • 32
  • 33
    • 0035910270 scopus 로고    scopus 로고
    • Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes
    • Krogh, A., Larsson, B., von Heijne, G. and Sonnhammer, E. L. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305, 567-580
    • (2001) J. Mol. Biol , vol.305 , pp. 567-580
    • Krogh, A.1    Larsson, B.2    von Heijne, G.3    Sonnhammer, E.L.4
  • 35
    • 33845930295 scopus 로고    scopus 로고
    • Demonstration of lysosomal localization for the mammalian ependymin-related protein using classical approaches combined with a novel density shift method
    • Della Valle, M. C., Sleat, D. E., Sohar, I., Wen, T., Pintar, J. E., Jadot, M. and Lobel, P. (2006) Demonstration of lysosomal localization for the mammalian ependymin-related protein using classical approaches combined with a novel density shift method. J. Biol. Chem. 281, 35436-35445
    • (2006) J. Biol. Chem , vol.281 , pp. 35436-35445
    • Della Valle, M.C.1    Sleat, D.E.2    Sohar, I.3    Wen, T.4    Pintar, J.E.5    Jadot, M.6    Lobel, P.7
  • 36
    • 0034650219 scopus 로고    scopus 로고
    • Endolyn is a mucin-like type I membrane protein targeted to lysosomes by its cytoplasmic tail
    • Ihrke, G., Gray, S. R. and Luzio, J. P. (2000) Endolyn is a mucin-like type I membrane protein targeted to lysosomes by its cytoplasmic tail. Biochem. J. 345, 287-296
    • (2000) Biochem. J , vol.345 , pp. 287-296
    • Ihrke, G.1    Gray, S.R.2    Luzio, J.P.3
  • 38
    • 0030137994 scopus 로고    scopus 로고
    • Intracellular trafficking of lysosomal membrane proteins
    • Hunziker, W. and Geuze, H. J. (1996) Intracellular trafficking of lysosomal membrane proteins. BioEssays 18, 379-389
    • (1996) BioEssays , vol.18 , pp. 379-389
    • Hunziker, W.1    Geuze, H.J.2
  • 40
    • 0035918290 scopus 로고    scopus 로고
    • The targeting of cystinosin to the lysosomal membrane requires a tyrosine-based signal and a novel sorting motif
    • Cherqui, S., Kalatzis, V., Trugnan, G. and Antignac, C. (2001) The targeting of cystinosin to the lysosomal membrane requires a tyrosine-based signal and a novel sorting motif. J. Biol. Chem. 276, 13314-13321
    • (2001) J. Biol. Chem , vol.276 , pp. 13314-13321
    • Cherqui, S.1    Kalatzis, V.2    Trugnan, G.3    Antignac, C.4
  • 41
    • 0021282451 scopus 로고
    • A coat of glycoconjugates on the inner surface of the lysosomal membrane in the rat kidney
    • Neiss, W. F. (1984) A coat of glycoconjugates on the inner surface of the lysosomal membrane in the rat kidney. Histochemistry 80, 603-608
    • (1984) Histochemistry , vol.80 , pp. 603-608
    • Neiss, W.F.1
  • 42
    • 0032742816 scopus 로고    scopus 로고
    • Asparagine-linked oligosaccharides protect Lamp-1 and Lamp-2 from intracellular proteolysis
    • Kundra, R. and Kornfeld, S. (1999) Asparagine-linked oligosaccharides protect Lamp-1 and Lamp-2 from intracellular proteolysis. J. Biol. Chem. 274, 31039-31046
    • (1999) J. Biol. Chem , vol.274 , pp. 31039-31046
    • Kundra, R.1    Kornfeld, S.2
  • 44
    • 0037659067 scopus 로고    scopus 로고
    • Nicastrin is required for assembly of presenilin/γ-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals
    • Li, T., Ma, G., Cai, H., Price, D. L. and Wong, P. C. (2003) Nicastrin is required for assembly of presenilin/γ-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals. J. Neurosci. 23, 3272-3277
    • (2003) J. Neurosci , vol.23 , pp. 3272-3277
    • Li, T.1    Ma, G.2    Cai, H.3    Price, D.L.4    Wong, P.C.5
  • 45
    • 28544435485 scopus 로고    scopus 로고
    • Lysosomes and autophagy in cell death control
    • Kroemer, G. and Jaattela, M. (2005) Lysosomes and autophagy in cell death control. Nat. Rev. Cancer 5, 886-897
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 886-897
    • Kroemer, G.1    Jaattela, M.2
  • 48
    • 67749122634 scopus 로고    scopus 로고
    • Sardiello, M., Palmieri, M., di Ronza, A., Medina, D. L., Valenza, M., Gennarino, V. A., Di Malta, C., Donaudy, F., Embrione, V., Polishchuk, R. S. et al. (2009) A gene network regulating lysosomal biogenesis and function. Science doi:10.1126/science.1174447
    • Sardiello, M., Palmieri, M., di Ronza, A., Medina, D. L., Valenza, M., Gennarino, V. A., Di Malta, C., Donaudy, F., Embrione, V., Polishchuk, R. S. et al. (2009) A gene network regulating lysosomal biogenesis and function. Science doi:10.1126/science.1174447


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