Right ventricular beneficial effects of beta adrenergic receptor kinase inhibitor (βARKct) gene transfer in a rat model of severe pressure overload

Biomedicine and Pharmacotherapy

Volumn 63, Issue 5, 2009, Pages 331-336

  Molina, Ezequiel J ^a   Gupta, Dipin ^a   Palma, Jon ^a   Gaughan, John P ^a   Macha, Mahender ^b  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Beta adrenergic receptor; Gene therapy; Heart failure; Pressure overload

Indexed keywords

ADENOVIRUS VECTOR; BETA ADRENERGIC RECEPTOR KINASE; BETA ADRENERGIC RECEPTOR KINASE INHIBITOR; G PROTEIN COUPLED RECEPTOR KINASE 2; INTERLEUKIN 1; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN SERINE THREONINE KINASE INHIBITOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SERCA2A PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIOVASCULAR GENE THERAPY; CONTROLLED STUDY; GENETIC MANIPULATION; HEART FAILURE; HEART LEFT VENTRICLE; HEART RIGHT VENTRICLE OVERLOAD; INFLAMMATION; INTRACORONARY INFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR DOWN REGULATION; VIRAL GENE THERAPY;

ADENOVIRIDAE; ANIMALS; BETA-GALACTOSIDASE; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEART FAILURE; HEART VENTRICLES; MALE; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SEVERITY OF ILLNESS INDEX; TRANSGENES;

EID: 68649117026     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2008.07.088     Document Type: Article

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