An investigation into effects of in Vitro Test condition on the release properties of theophylline from HPMC matrices using factorial design

Archives of Pharmacal Research

Volumn 32, Issue 7, 2009, Pages 1087-1096

  Petrovic, Aleksandra ^a   Ibric, Svetlana ^b   Trajkovic, Svetlana ^a   Popovic, Radmila ^a   Djuric, Zorica ^b   Popadic, Dragica ^a  

^a Galenika ad   (Serbia)

^b Faculty of Pharmacy   (Serbia)

Author keywords

Diffusion erosion kinetics; Dissolution; General experimental design; In vitro tests; Sustained release dosage form

Indexed keywords

AMINOPHYLLINE; HYDROXYPROPYLMETHYLCELLULOSE; POLYMER; THEOPHYLLINE;

ARTICLE; DRUG CAPSULE; DRUG DIFFUSION; DRUG EFFECT; DRUG FORMULATION; DRUG MECHANISM; DRUG RELEASE; EXPERIMENTAL DESIGN; FACTORIAL DESIGN; IN VITRO STUDY; RESPONSE VARIABLE; VISCOSITY;

AMINOPHYLLINE; CAPSULES; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG CARRIERS; DRUG COMBINATIONS; HYDROGEN-ION CONCENTRATION; KINETICS; METHYLCELLULOSE; MODELS, CHEMICAL; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; THEOPHYLLINE; VISCOSITY;

EID: 68649103530     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-009-1715-y     Document Type: Article

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