Multicolor fluorescence in situ hybridization and comparative genomic hybridization reveal molecular events in lung adenocarcinomas and squamous cell lung carcinomas

Biomedicine and Pharmacotherapy

Volumn 63, Issue 6, 2009, Pages 396-403

  Shen, Hua ^a   Gao, Wen ^a   Wu, Yu jie ^a   Qiu, Hai rong ^a   Shu, Yong qian ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

CGH; M FISH; NSCLC

Indexed keywords

CYTOKERATIN 1; TUBERIN;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CHROMOSOME 11; CHROMOSOME 11Q; CHROMOSOME 12; CHROMOSOME 12Q; CHROMOSOME 13Q; CHROMOSOME 14Q; CHROMOSOME 16P; CHROMOSOME 17; CHROMOSOME 17P; CHROMOSOME 17Q; CHROMOSOME 19Q; CHROMOSOME 1Q; CHROMOSOME 20Q; CHROMOSOME 21Q; CHROMOSOME 22Q; CHROMOSOME 2P; CHROMOSOME 2Q; CHROMOSOME 3P; CHROMOSOME 3Q; CHROMOSOME 4P; CHROMOSOME 5; CHROMOSOME 5P; CHROMOSOME 5Q; CHROMOSOME 6; CHROMOSOME 7P; CHROMOSOME 7Q; CHROMOSOME 8P; CHROMOSOME 8Q; CHROMOSOME 9P; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME REARRANGEMENT; CHROMOSOME TRANSLOCATION; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG ADENOCARCINOMA; LUNG RESECTION; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MOLECULAR BIOLOGY; PRIORITY JOURNAL;

ADENOCARCINOMA; ADULT; AGED; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CHROMOSOME ABERRATIONS; COMPARATIVE GENOMIC HYBRIDIZATION; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LUNG NEOPLASMS; MALE; MIDDLE AGED; TRANSLOCATION, GENETIC;

EID: 68649090502     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2008.08.010     Document Type: Article

References (39)

1. Jemal A., Thomas A., Murray T., and Thun M. Cancer statistics. CA Cancer J Clin 2002 52 (2002) 23-47
2. Wynder E.L., Goodman M.T., and Hoffmann D. Lung cancer etiology: challenges of the future. Carcinog Compr Surv 8 (1985) 39-62
3. Wang T.-J., and Zhou B.-S. Meta-analysis of the potential relationship between exposure to environmental tobacco smoke and lung cancer in nonsmoking Chinese women. Lung Cancer 16 (1997) 145-150
4. Luk C., Tsao M.-S., Bayani J., Shepherd F., and Squire J.A. Molecular cytogenetic analysis of non-small cell lung carcinoma by spectral karyotyping and comparative genomic hybridization. Cancer Genet Cytogenet 125 (2001) 87-99
5. Petersen I., Bujard M., Petersen S., Wolf G., Goeze A., Schwendel A., et al. Patterns of chromosomal imbalances in adenocarcinoma and squamous cell carcinoma of the lung. Cancer Res 57 (1997) 2331-2335
6. Pei J., Balsara B.R., Li W., Litwin S., Gabrielson E., Feder M., et al. Genomic imbalances in human lung adenocarcinomas and squamous cell carcinomas. Genes Chromosomes Cancer 31 (2001) 282-287
7. Kallioniemi A., Kallioniemi O.-P., Sudar D., Rutovitz D., Gray J.W., Waldman F., et al. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumours. Science 258 (1992) 818-821
8. Balsara B.R., Sonoda G., du Manoir S., Siegfried J.M., Gabrielson E., and Testa J.R. Comparative genomic hybridization analysis detects frequent, often high-level, overrepresentation of DNA sequences at 3q, 5p, 7p and 8q in human non-small cell lung carcinomas. Cancer Res 57 (1997) 2116-2120
9. Björkqvist A.M., Husgafvel-Pursiainen K., Anttila S., Karjalainen A., Tammilehto L., Mattson K., et al. DNA gains in 3q occur frequently in squamous cell carcinoma of the lung, but not in adenocarcinoma. Genes Chromosomes Cancer 22 (1998) 79-82
10. Speicher M.R., Petersen S., Uhrig S., Jentsch I., Fauth C., Eils R., et al. Analysis of chromosomal alterations in non-small cell lung cancer by multiplex-FISH, comparative genomic hybridization, and multicolor bar coding. Lab Invest 80 (2000) 1031-1041
11. Speicher M.R., Ballard S.G., and Ward D.C. Karyotyping human chromosomes by combinatorial multi-fluor FISH. Nat Genet 12 (1996) 368-375
12. Ashman J.N.E., Brigham J., Cowen M.E., Bahia H., Greenman J., Lind M., et al. Chromosomal alterations in small cell lung cancer revealed by multicolour fluorescent in situ hybridization. Int J Cancer 102 (2002) 230-236
13. Gunawan B., Schulten H.J., von Heydebreck A., Schmidt B., Enders C., Höer J., et al. Site-independent prognostic value of chromosome 9q loss in primary gastrointestinal stromal tumours. J Pathol 202 (2004) 421-429
14. Gunawan B., Mirzaie M., Schulten H.-J., Heidrich B., and Füzesi L. Molecular cytogenetic analysis of two primary squamous cell carcinomas of the lung using multicolor fluorescence in situ hybridization. Virchows Arch 439 (2001) 85-89
15. Allen D.G., Hutchins A.M., Hammet F., White D.J., Scurry J.P., Tabrizi S.N., et al. Genetic aberrations detected by comparative genomic hybridisation in vulvar cancers. Br J Cancer 86 (2002) 924-928 2828
16. Umayahara K., Numa F., Suehiro Y., Sakata A., Nawata S., Ogata H., et al. Comparative genomic hybridization detects genetic alterations during early stages of cervical cancer progression. Genes Chromosomes Cancer 33 (2002) 98-102
17. Oga A., Kong G., Tae K., Lee Y., and Sasaki K. Comparative genomic hybridization analysis reveals 3q gain resulting in genetic alteration in 3q in advanced oral squamous cell carcinoma. Cancer Genet Cytogenet 127 (2001) 24-29
18. Noguchi T., Kimura Y., Takeno S., Chujo M., Uchida Y., Mueller W., et al. Chromosomal imbalance in esophageal squamous cell carcinoma: 3q gain correlates with tumor progression but not prognostic significance. Oncol Rep 10 (2003) 1393-1400
19. Steinhart H., Bohlender J.E., Constantinidis J., Urbschat S., Fischer U., Iro H., et al. Genetic imbalances in preinvasive tissue of hypopharynx provide evidence for cytogenetic heterogeneity. Oncol Rep 8 (2001) 1229-1231
20. Massion P.P., Kuo W.-L., Stokoe D., Olshen A.B., Treseler P.A., Chin K., et al. Genomic copy number analysis of non-small cell lung cancer using array comparative genomic hybridization: implications of the phosphatidylinositol 3-kinase pathway. Cancer Res 62 (2002) 3636-3640
21. Brass N., Racz A., Heckel D., Remberger K., Sybrecht G.W., and Meese E.U. Amplification of the genes BCHE and SLC2A2 in 40% of squamous cell carcinoma of the lung. Cancer Res 57 (1997) 2290-2294
22. Virtanen C., Ishikawa Y., Honjoh D., Kimura M., Shimane M., Miyoshi T., et al. Integrated classification of lung tumors and cell lines by expression profiling. Proc Natl Acad Sci USA 99 (2002) 12357-12362
23. Tutt A., Gabriel A., Bertwistle D., Connor F., Paterson H., Peacock J., et al. Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification. Curr Biol 9 (1999) 1107-1110
24. Venkitaraman A.R. Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 108 (2002) 171-182
25. Astrinidis A., Khare L., Carsillo T., Smolarek T., Au K.S., Northrup H., et al. Mutational analysis of the tuberous sclerosis gene TSC2 in patients with pulmonary lymphangioleiomyomatosis. J Med Genet 37 (2000) 55-57
26. Calvo R., West J., Franklin W., Erickson P., Bemis L., Li E., et al. Altered HOX and WNT7A expression in human lung cancer. Proc Natl Acad Sci USA 97 (2000) 12776-12781
27. Chénais B., Derjuga A., Massrieh W., Red-Horse K., Bellingard V., Fisher S.J., et al. Functional and placental expression analysis of the human NRF3 transcription factor. Mol Endocrinol 19 (2005) 125-137
28. Sato J., Sata M., Nakamura H., Inoue S., Wada T., Takabatake N., et al. Role of thymidine phosphorylase on invasiveness and metastasis in lung adenocarcinoma. Int J Cancer 106 (2003) 8630-8670
29. Paez J.G., Jänne P.A., Lee J.C., Tracy S., Greulich H., Gabriel S., et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304 (2004) 1497-1500
30. Lynch T.J., Bell D.W., Sordella R., Gurubhagavatula S., Okimoto R.A., Brannigan B.W., et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small cell lung cancer to gefitinib. N Engl J Med 350 (2004) 2129-2139
31. Hirsch F.R., and Bunn Jr. P.A. Epidermal growth factor receptor inhibitors in lung cancer: smaller or larger molecules, selected or unselected populations?. J Clin Oncol 23 (2005) 9044-9047
32. Garnis C., Lockwood W.W., Vucic E., Ge Y., Girard L., Minna J.D., et al. High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH. Int J Cancer 118 (2006) 1556-1564
33. Petersen S., Aninat-Meyer M., Schluns K., Gellert K., Dietel M., and Petersen I. Chromosomal alterations in the clonal evolution to the metastatic stage of squamous cell carcinomas of the lung. Br J Cancer 82 (2000) 65-73
34. Massion P.P., Taflan P.M., Jamshedur Rahman S.M., Yildiz P., Shyr Y., Edgerton M.E., et al. Significance of p63 amplification and overexpression in lung cancer development and prognosis. Cancer Res 63 (2003) 7113-7121
35. Yokoi S., Yasui K., Iizasa T., Imoto I., Fujisawa T., and Inazawa J. TERC identified as a probable target within the 3q26 amplicon that is detected frequently in non-small cell lung cancers. Clin Cancer Res 9 (2003) 4705-4713
36. Samuels Y., Wang Z., Bardelli A., Silliman N., Ptak J., Szabo S., et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 304 (2004) 554
37. Tan D., Deeb G., Wang J., Slocum H.K., Winston J., Wiseman S., et al. HER-2/neu protein expression and gene alteration in stage I-IIIA non-small-cell lung cancer: a study of 140 cases using a combination of high throughput tissue microarray, immunohistochemistry, and fluorescent in situ hybridization. Diagn Mol Pathol 12 (2003) 201-211
38. Wikman H., Nymark P., Väyrynen A., Jarmalaite S., Kallioniemi A., Salmenkivi K., et al. CDK4 is a probable target gene in a novel amplicon at 12q13.3-q14.1 in lung cancer. Genes Chromosomes Cancer 42 (2005) 193-199
39. Yakut T., Egeli U., and Gebitekin C. Investigation of c-myc and p53 gene alterations in the tumor and surgical borderline tissues of NSCLC and effects on clinicopathologic behavior: by the FISH technique. Lung 181 (2003) 245-258