Chromosomal imbalance in esophageal squamous cell carcinoma: 3q gain correlates with tumor progression but not prognostic significance

Oncology Reports

Volumn 10, Issue 5, 2003, Pages 1393-1400

  Noguchi, Tsuyoshi ^a   Kimura, Yasuhiko ^a   Takeno, Shinsuke ^a   Chujo, Masao ^a   Uchida, Yuzo ^a   Mueller, Wolfram ^b   Gabbert, Helmut E ^b  

^a OITA UNIVERSITY   (Japan)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Comparative genomic hybridization; Esophageal squamous cell carcinoma; Genetic aberration

Indexed keywords

DNA;

ADULT; AGED; ARTICLE; CHROMOSOME 3; CHROMOSOME ABERRATION; DISEASE COURSE; ESOPHAGUS TUMOR; FEMALE; GENETICS; HUMAN; MALE; METABOLISM; MIDDLE AGED; NUCLEIC ACID HYBRIDIZATION; PATHOLOGY; PROGNOSIS; SQUAMOUS CELL CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 3; DISEASE PROGRESSION; DNA; ESOPHAGEAL NEOPLASMS; FEMALE; HUMANS; MALE; MIDDLE AGED; NUCLEIC ACID HYBRIDIZATION; PROGNOSIS;

EID: 1942433595     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.10.5.1393     Document Type: Article

References (43)

1. Siewert JR, Fink U, Beckurts KTE and Roder JD: Surgery of squamous cell carcinoma of the esophagus. Ann Oncol (Suppl. 3) 5: 1-7, 1994. (Pubitemid 24094619)
2. Ando N, Ozawa S, Kitagawa Y, Shinozawa Y and Kitajima M: Improvement in the results of surgical treatment of advanced squamous esophageal carcinoma during 15 consecutive years. Ann Surg 232: 225-232, 2000. (Pubitemid 30616724)
3. Shamma A, Doki Y, Shiozaki H, TsujinakaT, Yamamoto M, Inoue M, Yano M and Monden M: Cyclin D1 overexpression in esophageal dysplasia: a possible biomarker for carcinogenesis of esophageal squamous cell carcinoma. Int J Oncol 16: 261-266, 2000.
4. Takeno S, Noguchi T, Kikuchi R, Uchida Y, Yokoyama S and Mueller W: Prognostic value of cyclin B1 in patients with esophageal squamous cell carcinoma. Cancer 94: 2874-2881, 2002. (Pubitemid 34547686)
5. Shimada Y, Imamura M, Watanabe G, Uchida S, Harada H, Mokino T and Kano M: Prognostic factors of oesophageal squamous cell carcinoma from the perspective of molecular biology. Br J Cancer 80: 1281-1288, 1999. (Pubitemid 29264093)
6. Lam AKY: Molecular biology of esophageal squamous cell carcinoma. Crit Rev Oncol Hematol 33: 71-90, 2000.
7. Mandard AM, Hainaut P and Hollstein M: Genetic steps in the development of squamous cell carcinoma of the esophagus. Mutat Res 462: 335-342, 2000. (Pubitemid 30190239)
8. Kallioniemi A, Kallioniemi OP, Sudar D, Rutovitz D, Gray JW, Waldman F and Pinkel D: Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science 258: 818-821, 1992.
9. Knuutila S, Bjoekqvist AM, Autio K, Tarkkanen M, Wolf M, Monni O, Szymanska J, Larramendy ML, Tapper J, Pere H, El-Rifai W, Hemmer S, Wasenius VM, Vidgren V and Zhu Y: DNA copy number amplification in human neoplasms: revier of comparative genomic hybridization studies. Am J Pathol 152: 1107-1123, 1998. (Pubitemid 28221862)
10. Oga A, Kawauchi S, Izumi H, Ping LX, Furuya T and Sasaki K: New perspectives for tumor pathology provided by comparative genomic hybridization. Int J Clin Oncol 7: 133-137, 2002. (Pubitemid 34733477)
11. Yen CC, Chen YJ, Chen JT, Hsia JY, Chen PM, Liu JH, Fan FS, Chiou TJ, Wang WS and Lin CH: Comparative genomic hybridization of esophageal squamous cell carcinoma. Correlation between chromosomal aberrations and disease progression/prognosis. Cancer 92: 2769-2777, 2001. (Pubitemid 33091913)
12. Tada K, Oka M, Tangoku A, Hayashi H, Oga A and Sasaki K: Gains of 8q23-qter and 20q and loss of 11q22-qter in esophageal squamous cell carcinoma associated with lymph node metastasis Cancer 88: 268-273, 2000. (Pubitemid 30051808)
13. Pack SD, Karkera JD, Zhuang Z, Pak ED, Balan KV, Hwu P, Park WS, Pham T, Ault DO, Glaser M, Liotta L, Detera-Wadleigh SD and Wadleigh RG: Molecular cytogenetic fingerprinting of esophageal squamous cell carcinoma by comparative genomic hybridization reveals a consistent pattern of chromosomal alterations. Genes Chromosomes Cancer 25: 160-168, 1999. (Pubitemid 29226599)
14. Shinomiya T, Mori T, Ariyama Y, Sakabe T, Fukuda Y, Murakami Y, Nakamura Y and Inazawa J: Comparative genomic hybridization of squamous cell carcinoma of the esophagus: the possible involvement of the DPI gene in the 13q34 amplicon. Genes Chromosomes Cancer 24: 337-344, 1999. (Pubitemid 29115872)
15. Plessis LD, Dietzsch E, van Gele M, van Roy N, van Helden P, Parker MI, Mugwanya DK, De Groot M, Marx MP, Kotze MJ and Speleman F: Mapping of novel regions of DNA gain and loss by comparative genomic hybridization in esophageal carcinoma in the black and colored populations of South Africa. Cancer Res 59: 1877-1883, 1999. (Pubitemid 29186160)
16. Ueno T, Tangoku A, Yoshino S, Abe T, Toshimitsu H, Furuya T, Kawauchi S, Oga A, Oka M and Sasaki K: Gain of 5p15 detected by comparative genomic hybridization as an independent marker of poor prognosis in patients with esophageal squamous cell carcinoma. Clin Cancer Res 8: 526-533, 2002. (Pubitemid 34193973)
17. Chujo M, Noguchi T, Miura T, Arinaga M, Uchida Y and Tagawa Y: Comparative genomic hybridization analysis detected frequent overrepresentation of chromosome 3q in squamous cell carcinoma of the lung. Lung Cancer 38: 23-29, 2002. (Pubitemid 35303356)
18. Noguchi T, Wirtz HC, Michaelis S, Gabbert HE and Mueller W: Chromosomal imbalances in gastric cancer. Correlation with histologic subtypes and tumor progression. Am J Clin Pathol 115: 828-834, 2001. (Pubitemid 32476708)
19. Bayerlein K, Rith T, Verdorfer I, Liehr T, Wolff E, Girod S and Gebhart E: I-FISH control of CGH-detected gain of DNA sequence copy number in oral squamous cell carcinoma (OSCC). Anticancer Res 20: 427-432, 2000. (Pubitemid 30189790)
20. Bergamo NA, Rogatto SR, Poli-Frederico RC, Reis PP, Kowalski LP, Zielenska M and Squire JA: Comparative genomic hybridization analysis detects frequent over-representation of DNA sequences at 3q, 7p, and 8q in head and neck carcinomas. Cancer Genet Cytogenet 119: 48-55, 2000. (Pubitemid 30254218)
21. Welkoborsky HJ, Bernaer HS, Riazimand HS, Jacob R, Mann WJ, Hinni ML: Patterns of chromosomal aberrations in metastasizing and nonmetastasizing squamous cell carcinomas of the oropharynx and hypopharynx. Ann Otol Rhinol Laryngol 109: 401-410, 2000. (Pubitemid 30198532)
22. Heselmeyer K, Macville M, Schroeck E, Blegen H, Hellstroem AC, Shah K, Auer G and Ried T: Advanced-stage cervical carcinomas are defined by a recurrent pattern of chromosomal aberrations revealing high genetic instability and a consistent gain of chromosome arm 3q. Genes Chromosomes Cancer 19: 233-240, 1997. (Pubitemid 27330234)
23. Kirchhoff M, Rose H, Petersen BL, Maahr J, Gerdes T, Lundsteen C, Bryndorf T, Kryger-Baggesen N, Christensen L, Engelholm SA and Philip J: Comparative genomic hybridization reveals a recurrent pattern of chromosomal aberrations in severe dysplasia/carcinoma in situ of the cervix and in advanced-stage cervical carcinoma. Genes Chromosom Cancer 24: 144-150, 1999. (Pubitemid 29025260)
24. Kettunen E, El-Rifai W, Bjorkqvist AM, Wolff H, Karjalainen A, Anttila S, Mattson K, Husgafvel-Pursioinen K and Knuutila S: A broad amplification at 3q in squamous cell lung cancer - a fluorescence in situ hybridization study. Cancer Genet Cytogenet 117: 66-70, 2000. (Pubitemid 30099659)
25. Racz A, Brass N, Heckel D, Pahl S, Remberger K and Meese E: Expression analysis of genes at 3q26-27 involved in frequent amplification in squamous cell lung carcinoma. Eur J Cancer 35: 641-646, 1999. (Pubitemid 29192975)
26. Takeo S, Arai H, Kusano N, Harada T, Furuya T, Kawauchi S, Oga A, Hirano T, Yoshida T, Okita K and Sasaki K: Examination of oncogene amplification by genomic DNA microarray in hepatocellular carcinomas: comparison with comparative genomic hybridization analysis. Cancer Genet Cytogenet 130: 127-132, 2001. (Pubitemid 33033229)
27. Lee BK, Diebel E, Neukam FW, Wiltfang J and Ries J: Diagnostic and prognostic relevance of expression of human telomerase subunits in oral cancer. Int J Oncol 19: 1063-1068, 2001.
28. Shayesteh L, Lu Y, Kuo WL, Baldocchi R, Godfrey T, Collins C, Pinkel D, Powell B, Mills GB and Gray JW: PIK3CA is implicated as an oncogene in ovarian cancer. Nat Genet 21: 99-102, 1999. (Pubitemid 29036292)
29. Ma YY, Wei SJ, Lin YC, Lung LC, Chang TC, Whang-Peng J, Liu JM, Yang DM, Yang WK and Shen CY: PIK3CA as an oncogene in cervical cancer. Oncogene 19: 2739-2744, 2000. (Pubitemid 30339223)
30. Redon R, Muller D, Caulee K, Wanherdrick K, Abecassis J and du Manoir S: A simple specific pattern of chromosomal aberrations at early stages of head and neck squamous cell carcinomas. Cancer Res 61: 4122-4129, 2001.
31. Imoto I, Pimkhaokham A, Fukuda Y, Yang ZQ, Shimada Y, Nomura N, Hirai H, Imamura M and Inazawa J: SNO is a probable target for gene amplification at 3q26 in squamous-cell carcinomas of the esophagus. Biochem Biophys Res Comn 286: 559-565, 2001. (Pubitemid 32912983)
32. Balsara BR, Sonoda G, du Manoir S, Siegfried JM, Gabrielson E and Testa JR: Comparative genomic hybridization analysis detects frequent, often high-level, overexpression of DNA sequences at 3q, 5p, 7p, and 8q in human non-small cell lung carcinomas. Cancer Res 57: 2116-2120, 1997. (Pubitemid 27247023)
33. Liehr T, Ries J, Wolff E, Fiedler W, Dahse R, Ernst G, Steininger H, Koscielny S, Girod S and Gebhart E: Gain of DNA copy number on chromosome 3q26-qter and 5p15-qter is a frequent finding in head and neck squamous cell carcinomas. Int J Mol Med 2: 173-179, 1998.
34. Shay JW and Wright WE: Implications of mapping the human telomerase gene (hTERT) as the most distal gene on chromosome 5p. Neaplasia 2: 195-201, 2000.
35. Komiya T, Kawase I, Nitta T, Yasumitsu T, Kikui M, Fukuoka M, Nakagawa K and Hirashima T: Prognostic significance of hTERT expression in non-small cell lung cancer. Int J Oncol 16: 1173-1177, 2000.
36. Mitsui A, Kuwabara Y, Iwase H, Mitani M, Shinoda N, Sato A, Toyama T, Sugiura M, Suzuki T, Kato J and Fujii Y: Telomerase activity in esophageal squamous cell carcinoma: down-regulation by chemotherapeutic agent. I Surg Oncol 79: 37-45, 2002. (Pubitemid 34049543)
37. Zhang H, Kobayashi R, Galaktionov K and Beach D: p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase. Cell 82: 915-925, 1995.
38. Signoretti S, Marcotullio L, Richardson A, Ramaswamy S, Isaac B, Rue M, Monti F, Loda M and Pagano M: Oncogenic role of the ubiquitin ligase Skp2 in human breast cancer. J Clin Invest 110: 633-641, 2002. (Pubitemid 34988787)
39. Masuda TA, Inoue H, Sonoda H, Mine S, Yoshikawa Y, Nakayama K, Nakayama K and Mori M: Clinical and biological significance of S-phase kinase-associated protein 2 (Skp2) gene expression in gastric carcinoma: modulation of malignant phenotype by Skp2 overexpression, possibly via p27 proteolysis. Cancer Res 62: 3819-3825, 2002. (Pubitemid 34728867)
40. Ohta M, Inoue H, Cotticelli MG, Kastury K, Baffa R, Palazzo J, Siprashvili Z, Mori M, McCue P, Druck T, Croce CM and Huebner K: The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell 84: 587-597, 1996. (Pubitemid 26071739)
41. Noguchi T, Mueller W, Wirtz HC, Willers R and Gabbert HE: FHIT gene in gastric cancer: association with tumor progression and prognosis. J Pathol 188: 378-381, 1999. (Pubitemid 29327435)
42. Mori M, Mimori K, Shiraishi T, Alder H, Inoue H, Tanaka Y, Sugimachi K, Huebner K and Croce CM: Altered expression of Fhit in carcinoma and precarcinomatous lesions of the esophagus. Cancer Res 60: 1177-1182, 2000. (Pubitemid 30151977)
43. Noguchi T, Takeno S, Kimura Y, Uchida Y, Daa T, Yokoyama S, Gabbert HE and Mueller W: FHIT expression and hypermethylation in esophageal squamous cell carcinoma. Int J Mol Med 11: 441-447, 2003.