메뉴 건너뛰기




Volumn 63, Issue 5, 2009, Pages 375-379

Tamoxifen inhibits proliferation and induces apoptosis in human hepatocellular carcinoma cell line HepG2 via down-regulation of survivin expression

Author keywords

Apoptosis; Estrogen receptor; Survivin

Indexed keywords

ESTROGEN RECEPTOR; SURVIVIN; TAMOXIFEN;

EID: 68649084732     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2008.09.010     Document Type: Article
Times cited : (19)

References (34)
  • 1
    • 0031052651 scopus 로고    scopus 로고
    • Tamoxifen for the treatment of malignancies other than breast and endometrial carcinoma
    • Gelmann E. Tamoxifen for the treatment of malignancies other than breast and endometrial carcinoma. Semin Oncol 24 (1997) 165-170
    • (1997) Semin Oncol , vol.24 , pp. 165-170
    • Gelmann, E.1
  • 2
    • 0028272869 scopus 로고
    • Randomized controlled trial of tamoxifen versus placebo in inoperable hepatocellular carcinoma
    • Elba S., Giannuzzi V., Misciagna G., and Manghisi O.G. Randomized controlled trial of tamoxifen versus placebo in inoperable hepatocellular carcinoma. Ital J Gastroenterol 26 (1994) 66-68
    • (1994) Ital J Gastroenterol , vol.26 , pp. 66-68
    • Elba, S.1    Giannuzzi, V.2    Misciagna, G.3    Manghisi, O.G.4
  • 4
    • 0027500115 scopus 로고
    • Sex hormone receptors in hepatocellular carcinoma. Is there a rationale for hormonal treatment?
    • Boix L., Bruix J., Castells A., Fuster J., Bru C., Visa J., et al. Sex hormone receptors in hepatocellular carcinoma. Is there a rationale for hormonal treatment?. J Hepatol 17 (1993) 187-191
    • (1993) J Hepatol , vol.17 , pp. 187-191
    • Boix, L.1    Bruix, J.2    Castells, A.3    Fuster, J.4    Bru, C.5    Visa, J.6
  • 5
    • 0028897375 scopus 로고
    • Variant estrogen receptor messenger RNA species detected in human primary hepatocellular carcinoma
    • Villa E., Camellini L., Dugani A., Zucchi F., Grottola A., Merighi A., et al. Variant estrogen receptor messenger RNA species detected in human primary hepatocellular carcinoma. Cancer Res 55 (1995) 498-500
    • (1995) Cancer Res , vol.55 , pp. 498-500
    • Villa, E.1    Camellini, L.2    Dugani, A.3    Zucchi, F.4    Grottola, A.5    Merighi, A.6
  • 7
    • 0035181465 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen-induced apoptosis
    • Mandlekar S., and Kong A.N. Mechanisms of tamoxifen-induced apoptosis. Apoptosis 6 (2001) 469-477
    • (2001) Apoptosis , vol.6 , pp. 469-477
    • Mandlekar, S.1    Kong, A.N.2
  • 8
    • 0032585770 scopus 로고    scopus 로고
    • 2+ influx in the mechanism of tamoxifen-induced apoptosis in HepG2 human hepatoblastoma cells
    • 2+ influx in the mechanism of tamoxifen-induced apoptosis in HepG2 human hepatoblastoma cells. Cancer Lett 147 (1999) 115-123
    • (1999) Cancer Lett , vol.147 , pp. 115-123
    • Kim, J.A.1    Young, S.K.2    Jung, M.W.3    Lee, S.H.4    Yong, S.L.5
  • 9
    • 0033778727 scopus 로고    scopus 로고
    • Role of NADPH oxidase in tamoxifen-induced generation of reactive oxygen species and apoptosis in HepG2 human hepatoblastoma cells
    • Lee Y.S., Kang Y.S., and Lee S.H. Role of NADPH oxidase in tamoxifen-induced generation of reactive oxygen species and apoptosis in HepG2 human hepatoblastoma cells. Cell Death Differ 7 (2000) 925-932
    • (2000) Cell Death Differ , vol.7 , pp. 925-932
    • Lee, Y.S.1    Kang, Y.S.2    Lee, S.H.3
  • 10
    • 0032519653 scopus 로고    scopus 로고
    • Inhibition of the membrane translocation and activation of protein kinase C, and potentiation of doxorubicin-induced apoptosis of hepatocellular carcinoma cells by tamoxifen
    • Cheng A.L., Chuang S.E., Fine R.L., Yeh K.H., Liao C.M., Lay J.D., et al. Inhibition of the membrane translocation and activation of protein kinase C, and potentiation of doxorubicin-induced apoptosis of hepatocellular carcinoma cells by tamoxifen. Biochem Pharmacol 55 (1998) 523-531
    • (1998) Biochem Pharmacol , vol.55 , pp. 523-531
    • Cheng, A.L.1    Chuang, S.E.2    Fine, R.L.3    Yeh, K.H.4    Liao, C.M.5    Lay, J.D.6
  • 11
    • 0032403126 scopus 로고    scopus 로고
    • IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas [CD95], Bax, caspases, and anticancer drugs
    • Tamm I., Wang Y., Sausville E., Scudiero D.A., Vigna N., Oltersdorf T., et al. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas [CD95], Bax, caspases, and anticancer drugs. Cancer Res 58 (1998) 5315-5320
    • (1998) Cancer Res , vol.58 , pp. 5315-5320
    • Tamm, I.1    Wang, Y.2    Sausville, E.3    Scudiero, D.A.4    Vigna, N.5    Oltersdorf, T.6
  • 12
  • 13
    • 0032080335 scopus 로고    scopus 로고
    • Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting
    • Ambrosini G., Adida C., Sirugo G., and Altieri D.C. Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting. J Biol Chem 273 (1998) 11177-11182
    • (1998) J Biol Chem , vol.273 , pp. 11177-11182
    • Ambrosini, G.1    Adida, C.2    Sirugo, G.3    Altieri, D.C.4
  • 14
    • 0032986544 scopus 로고    scopus 로고
    • A novel anti-apoptosis gene: reexpression of survivin messenger RNA as a prognosis marker in non small cell lung cancers
    • Monzo M., Rosell R., Felip E., Astudillo J., Sanchez J.J., Maestre J., et al. A novel anti-apoptosis gene: reexpression of survivin messenger RNA as a prognosis marker in non small cell lung cancers. J Clin Oncol 17 (1999) 2100-2104
    • (1999) J Clin Oncol , vol.17 , pp. 2100-2104
    • Monzo, M.1    Rosell, R.2    Felip, E.3    Astudillo, J.4    Sanchez, J.J.5    Maestre, J.6
  • 15
    • 0032533494 scopus 로고    scopus 로고
    • Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer
    • Kawasaki H., Altieri D.C., Lu C.D., Toyoda M., Tenjo T., and Tanigawa N. Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer. Cancer Res 58 (1998) 5071-5074
    • (1998) Cancer Res , vol.58 , pp. 5071-5074
    • Kawasaki, H.1    Altieri, D.C.2    Lu, C.D.3    Toyoda, M.4    Tenjo, T.5    Tanigawa, N.6
  • 16
    • 0032152769 scopus 로고    scopus 로고
    • Molecular basis of spontaneous regression of neuroblastoma: role of neurotrophic signals and genetic abnormalities
    • Nakagawara A. Molecular basis of spontaneous regression of neuroblastoma: role of neurotrophic signals and genetic abnormalities. Hum Cell 11 (1998) 115-124
    • (1998) Hum Cell , vol.11 , pp. 115-124
    • Nakagawara, A.1
  • 17
    • 0036551756 scopus 로고    scopus 로고
    • Survivin expression and resistance to anticancer treatments: perspectives for new therapeutic interventions
    • Zaffaroni N., and Daidone M.G. Survivin expression and resistance to anticancer treatments: perspectives for new therapeutic interventions. Drug Resist Updat 5 (2002) 65-72
    • (2002) Drug Resist Updat , vol.5 , pp. 65-72
    • Zaffaroni, N.1    Daidone, M.G.2
  • 19
    • 0342657718 scopus 로고    scopus 로고
    • A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy
    • Olie R.A., Simoes-Wust A.P., Baumann B., Leech S.H., Fabbro D., Stahel R.A., et al. A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy. Cancer Res 60 (2000) 2805-2809
    • (2000) Cancer Res , vol.60 , pp. 2805-2809
    • Olie, R.A.1    Simoes-Wust, A.P.2    Baumann, B.3    Leech, S.H.4    Fabbro, D.5    Stahel, R.A.6
  • 20
    • 0042170180 scopus 로고    scopus 로고
    • Survivin is required for stable checkpoint activation in taxol-treated HeLa cells
    • Carvalho A., Carmena M., Sambade C., Earnshaw W.C., and Wheatley S.P. Survivin is required for stable checkpoint activation in taxol-treated HeLa cells. J Cell Sci 116 (2003) 2987-2998
    • (2003) J Cell Sci , vol.116 , pp. 2987-2998
    • Carvalho, A.1    Carmena, M.2    Sambade, C.3    Earnshaw, W.C.4    Wheatley, S.P.5
  • 21
    • 2442608732 scopus 로고    scopus 로고
    • Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR [FOXO1]
    • Daly C., Wong V., Burova E., Wei Y., Zabski S., Griffiths J., et al. Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR [FOXO1]. Genes Dev 18 (2004) 1060-1071
    • (2004) Genes Dev , vol.18 , pp. 1060-1071
    • Daly, C.1    Wong, V.2    Burova, E.3    Wei, Y.4    Zabski, S.5    Griffiths, J.6
  • 22
    • 2442534189 scopus 로고    scopus 로고
    • Induction of survivin expression by taxol (paclitaxel) is an early event, which is independent of taxol-mediated G2/M arrest
    • Ling X., Bernacki R.J., Brattain M.G., and Li F. Induction of survivin expression by taxol (paclitaxel) is an early event, which is independent of taxol-mediated G2/M arrest. J Biol Chem 279 (2004) 15196-15203
    • (2004) J Biol Chem , vol.279 , pp. 15196-15203
    • Ling, X.1    Bernacki, R.J.2    Brattain, M.G.3    Li, F.4
  • 23
    • 37649020907 scopus 로고    scopus 로고
    • Survivin gene RNA interference inhibits proliferation, induces apoptosis, and enhances radiosensitivity in HeLa cells
    • Song H., Xin X.Y., Xiao F., Wang D.T., Yue Q.H., and Han X. Survivin gene RNA interference inhibits proliferation, induces apoptosis, and enhances radiosensitivity in HeLa cells. Eur J Obstet Gynecol Reprod Biol 136 (2008) 83-89
    • (2008) Eur J Obstet Gynecol Reprod Biol , vol.136 , pp. 83-89
    • Song, H.1    Xin, X.Y.2    Xiao, F.3    Wang, D.T.4    Yue, Q.H.5    Han, X.6
  • 24
    • 24644436544 scopus 로고    scopus 로고
    • Induction of apoptosis in human ovarian epithelial cancer cells by antisurvivin oligonucleotides
    • Ma X., Wang S., Zhou J., Xing H., Xu G., Wang B., et al. Induction of apoptosis in human ovarian epithelial cancer cells by antisurvivin oligonucleotides. Oncol Rep 14 (2005) 275-279
    • (2005) Oncol Rep , vol.14 , pp. 275-279
    • Ma, X.1    Wang, S.2    Zhou, J.3    Xing, H.4    Xu, G.5    Wang, B.6
  • 25
    • 13544273457 scopus 로고    scopus 로고
    • Knockdown of survivin gene expression by RNAi induces apoptosis in human hepatocellular carcinoma cell line SMMC-7721
    • Cheng S.Q., Wang W.L., Yan W., Li Q.L., Wang L., and Wang W.Y. Knockdown of survivin gene expression by RNAi induces apoptosis in human hepatocellular carcinoma cell line SMMC-7721. World J Gastroenterol 11 (2005) 756-759
    • (2005) World J Gastroenterol , vol.11 , pp. 756-759
    • Cheng, S.Q.1    Wang, W.L.2    Yan, W.3    Li, Q.L.4    Wang, L.5    Wang, W.Y.6
  • 26
    • 0030006468 scopus 로고    scopus 로고
    • Tamoxifen modulates protein kinase C via oxidative stress in estrogen receptor-negative breast cancer cells
    • Gundimeda U., Chen Z.H., and Gopalakrishna R. Tamoxifen modulates protein kinase C via oxidative stress in estrogen receptor-negative breast cancer cells. J Biol Chem 271 (1996) 13504-13514
    • (1996) J Biol Chem , vol.271 , pp. 13504-13514
    • Gundimeda, U.1    Chen, Z.H.2    Gopalakrishna, R.3
  • 27
    • 42449120108 scopus 로고    scopus 로고
    • Inhibition of fibroblast growth factor 2-induced apoptosis involves survivin expression, protein kinase C alpha activation and subcellular translocation of Smac in human small cell lung cancer cells
    • Xiao D., Wang K., Zhou J., Cao H., Deng Z., Hu Y., et al. Inhibition of fibroblast growth factor 2-induced apoptosis involves survivin expression, protein kinase C alpha activation and subcellular translocation of Smac in human small cell lung cancer cells. Acta Biochim Biophys Sin 40 (2008) 297-303
    • (2008) Acta Biochim Biophys Sin , vol.40 , pp. 297-303
    • Xiao, D.1    Wang, K.2    Zhou, J.3    Cao, H.4    Deng, Z.5    Hu, Y.6
  • 28
    • 38149109698 scopus 로고    scopus 로고
    • Matrigel-induced acinar differentiation is followed by apoptosis in HSG cells
    • Szlávik V., Vág J., Markó K., Demeter K., Madarász E., Oláh I., et al. Matrigel-induced acinar differentiation is followed by apoptosis in HSG cells. J Cell Biochem 103 (2008) 284-295
    • (2008) J Cell Biochem , vol.103 , pp. 284-295
    • Szlávik, V.1    Vág, J.2    Markó, K.3    Demeter, K.4    Madarász, E.5    Oláh, I.6
  • 29
    • 0029587220 scopus 로고
    • Tamoxifen inhibits hepatoma cell growth through an estrogen receptor independent mechanism
    • Jiang S.Y., Shyu R.Y., Yeh M.Y., and Jordan V.C. Tamoxifen inhibits hepatoma cell growth through an estrogen receptor independent mechanism. J Hepatol 23 (1995) 712-719
    • (1995) J Hepatol , vol.23 , pp. 712-719
    • Jiang, S.Y.1    Shyu, R.Y.2    Yeh, M.Y.3    Jordan, V.C.4
  • 30
    • 0033857286 scopus 로고    scopus 로고
    • Use of tamoxifen in hepatocellular carcinoma: a review and paradigm shift
    • Tan C.K., Chow P.K., Findlay M., Wong C., and Machin D. Use of tamoxifen in hepatocellular carcinoma: a review and paradigm shift. J Gastroenterol Hepatol 15 (2000) 725-729
    • (2000) J Gastroenterol Hepatol , vol.15 , pp. 725-729
    • Tan, C.K.1    Chow, P.K.2    Findlay, M.3    Wong, C.4    Machin, D.5
  • 31
    • 0021333099 scopus 로고
    • Estrogen receptormediated and cytotoxic effects of the antiestrogens tamoxifen and 4-hydroxytamoxifen
    • Taylor C.M., Blanchard B., and Zava D.T. Estrogen receptormediated and cytotoxic effects of the antiestrogens tamoxifen and 4-hydroxytamoxifen. Cancer Res 44 (1984) 1409-1414
    • (1984) Cancer Res , vol.44 , pp. 1409-1414
    • Taylor, C.M.1    Blanchard, B.2    Zava, D.T.3
  • 32
    • 0026425653 scopus 로고
    • Distribution of tamoxifen and its metabolites in rat and human tissues during steady-state treatment
    • Lien E.A., Sohlheim E., and Ueland P.M. Distribution of tamoxifen and its metabolites in rat and human tissues during steady-state treatment. Cancer Res 51 (1991) 4837-4844
    • (1991) Cancer Res , vol.51 , pp. 4837-4844
    • Lien, E.A.1    Sohlheim, E.2    Ueland, P.M.3
  • 33
    • 0031471007 scopus 로고    scopus 로고
    • Acquired tamoxifen resistance in human breast cancer - potential mechanisms and clinical implications
    • Johnston S.R. Acquired tamoxifen resistance in human breast cancer - potential mechanisms and clinical implications. Anticancer Drugs 8 (1997) 911-930
    • (1997) Anticancer Drugs , vol.8 , pp. 911-930
    • Johnston, S.R.1
  • 34
    • 0029987574 scopus 로고    scopus 로고
    • Tamoxifen treatment in hepatocellular carcinoma
    • Farinati F. Tamoxifen treatment in hepatocellular carcinoma. Gastroenterology 111 (1996) 272-274
    • (1996) Gastroenterology , vol.111 , pp. 272-274
    • Farinati, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.