메뉴 건너뛰기




Volumn 29, Issue 8, 2009, Pages 3035-3042

Spontaneous tumor formation in Trp53-deficient epidermis mediated by chromosomal instability and inflammation

Author keywords

Chromosome instability; Inflammation; Mitotic checkpoint; NF B; Rb; Skin cancer; Trp53

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P53; RETINOBLASTOMA PROTEIN;

EID: 68549096090     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (14)

References (38)
  • 1
    • 34248379012 scopus 로고    scopus 로고
    • Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: Lessons from recent developments in the IARC TP53 database
    • DOI 10.1002/humu.20495
    • Petitjean A, Mathe E, Kato S, Ishioka C, Tavtigian SV, Hainaut P and Olivier M: Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Hum Mutat 25(6): 622-629, 2007. (Pubitemid 46744292)
    • (2007) Human Mutation , vol.28 , Issue.6 , pp. 622-629
    • Petitjean, A.1    Mathe, E.2    Kato, S.3    Ishioka, C.4    Tavtigian, S.V.5    Hainaut, P.6    Olivier, M.7
  • 2
    • 33845270990 scopus 로고    scopus 로고
    • Regulating the p53 pathway: In vitro hypotheses, in vivo veritas
    • Toledo F and Wahl GM: Regulating the p53 pathway: in vitro hypotheses, in vivo veritas. Nat Rev Cancer 6(12): 909-23.2006.
    • (2006) Nat Rev Cancer , vol.6 , Issue.12 , pp. 909-923
    • Toledo, F.1    Wahl, G.M.2
  • 3
    • 0035734285 scopus 로고    scopus 로고
    • Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
    • DOI 10.1038/ng747
    • Jonkers J, Meuwissen R, van der Gulden H, Peterse H, van der Valk M and Berns A: Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat Genet 29(4): 418-425, 2001. (Pubitemid 34326692)
    • (2001) Nature Genetics , vol.29 , Issue.4 , pp. 418-425
    • Jonkers, J.1    Meuwissen, R.2    Van Der Gulden, H.3    Peterse, H.4    Van Der Valk, M.5    Berns, A.6
  • 4
    • 38849167565 scopus 로고    scopus 로고
    • Spontaneous squamous cell carcinoma induced by the somatic inactivation of retinoblastoma and Trp53 tumor suppressors
    • DOI 10.1158/0008-5472.CAN-07-3049
    • Martinez-Cruz AB, Santos M, Lara MF, Segrelles C, Ruiz S, Moral M, Lorz C, Garcia-Escudero R and Paramio JM: Spontaneous squamous cell carcinoma induced by the somatic inactivation of retinoblastoma and Trp53 tumor suppressors. Cancer Res 68(3): 683-692, 2008. (Pubitemid 351206743)
    • (2008) Cancer Research , vol.68 , Issue.3 , pp. 683-692
    • Martinez-Cruz, A.B.1    Santos, M.2    Lara, M.F.3    Segrelles, C.4    Ruiz, S.5    Moral, M.6    Lorz, C.7    Garcia-Escudero, R.8    Paramio, J.M.9
  • 9
    • 0037316303 scopus 로고    scopus 로고
    • A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
    • DOI 10.1093/bioinformatics/19.2.185
    • Bolstad BM, Irizarry RA, Astrand M and Speed TP: A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 19(2): 185-193, 2003. (Pubitemid 36181903)
    • (2003) Bioinformatics , vol.19 , Issue.2 , pp. 185-193
    • Bolstad, B.M.1    Irizarry, R.A.2    Astrand, M.3    Speed, T.P.4
  • 13
    • 0029881977 scopus 로고    scopus 로고
    • Abnormal centrosome amplification in the absence of p53
    • Fukasawa K, Choi T, Kuriyama R, Rulong S, and Vande Woude GF: Abnormal centrosome amplification in the absence of p53. Science 271(5256): 1744-1747, 1996. (Pubitemid 26102826)
    • (1996) Science , vol.271 , Issue.5256 , pp. 1744-1747
    • Fukasawa, K.1    Choi, T.2    Kuriyama, R.3    Rulong, S.4    Vande Woude, G.F.5
  • 14
    • 34447130136 scopus 로고    scopus 로고
    • An inducible mouse model for skin cancer reveals distinct roles for gain- And loss-of-function p53 mutations
    • Caulin C, Nguyen T, Lang GA, Goepfert TM, Brinkley BR, Cai WW, Lozano G and Roop DR: An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations. J Clin Invest 117(7): 1893-1901, 2007.
    • (2007) J Clin Invest , vol.117 , Issue.7 , pp. 1893-1901
    • Caulin, C.1    Nguyen, T.2    Lang, G.A.3    Goepfert, T.M.4    Brinkley, B.R.5    Cai, W.W.6    Lozano, G.7    Roop, D.R.8
  • 15
    • 0032500106 scopus 로고    scopus 로고
    • Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis
    • Wang XJ, Greenhalgh DA, Jiang A, He D, Zhong L, Medina D, Brinkley BR and Roop DR: Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis. Oncogene 17(1): 35-45, 1998. (Pubitemid 28360527)
    • (1998) Oncogene , vol.17 , Issue.1 , pp. 35-45
    • Wang, X.-J.1    Greenhalgh, D.A.2    Jiang, A.3    He, D.4    Zhong, L.5    Medina, D.6    Brinkley, B.R.7    Roop, D.R.8
  • 16
    • 18144412429 scopus 로고    scopus 로고
    • Guilt by association? p53 and the development of aneuploidy in cancer
    • DOI 10.1016/j.bbrc.2005.03.157, Apoptosis Control
    • Duensing A and Duensing S: Guilt by association? p53 and the development of aneuploidy in cancer. Biochem Biophys Res Commun 331(3): 694-700, 2005. (Pubitemid 40615499)
    • (2005) Biochemical and Biophysical Research Communications , vol.331 , Issue.3 , pp. 694-700
    • Duensing, A.1    Duensing, S.2
  • 17
    • 51649092237 scopus 로고    scopus 로고
    • P53, cyclin-dependent kinase and abnormal amplification of centrosomes
    • Fukasawa K: P53, cyclin-dependent kinase and abnormal amplification of centrosomes. Biochim Biophys Acta 1786(1): 15-23, 2008.
    • (2008) Biochim Biophys Acta , vol.1786 , Issue.1 , pp. 15-23
    • Fukasawa, K.1
  • 18
    • 33746437470 scopus 로고    scopus 로고
    • Exploiting the p53 pathway for the diagnosis and therapy of human cancer
    • DOI 10.1101/sqb.2005.70.049
    • Lane DP: Exploiting the p53 pathway for the diagnosis and therapy of human cancer. Cold Spring Harb Symp Quant Biol 70: 489-497, 2005. (Pubitemid 44124906)
    • (2005) Cold Spring Harbor Symposia on Quantitative Biology , vol.70 , pp. 489-497
    • Lane, D.P.1
  • 19
    • 0038819656 scopus 로고    scopus 로고
    • Contribution of stem cells and differentiated cells to epidermal tumours
    • DOI 10.1038/nrc1096
    • Owens DM and Watt FM: Contribution of stem cells and differentiated cells to epidermal tumours. Nat Rev Cancer 3(6): 444-451, 2003. (Pubitemid 37328848)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.6 , pp. 444-451
    • Owens, D.M.1    Watt, F.M.2
  • 20
    • 65649128527 scopus 로고    scopus 로고
    • On the origin of epidermal cancers
    • Lorz C, Segrelles C and Paramio JM: On the origin of epidermal cancers. Curr Mol Med 9(3): 353-364, 2009.
    • (2009) Curr Mol Med , vol.9 , Issue.3 , pp. 353-364
    • Lorz, C.1    Segrelles, C.2    Paramio, J.M.3
  • 21
    • 0028830735 scopus 로고
    • Changes in expression of apoptosis-associated genes in skin mark early catagen
    • Seiberg M, Marthinuss J and Stenn KS: Changes in expression of apoptosis-associated genes in skin mark early catagen. J Invest Dermatol 104(1): 78-82, 1995.
    • (1995) J Invest Dermatol , vol.104 , Issue.1 , pp. 78-82
    • Seiberg, M.1    Marthinuss, J.2    Stenn, K.S.3
  • 22
    • 35348838471 scopus 로고    scopus 로고
    • NF-κB gene signatures and p53 mutations in head and neck squamous cell carcinoma
    • DOI 10.1158/1078-0432.CCR-07-1544
    • Ferris RL and Grandis JR: NF-κB gene signatures and p53 mutations in head and neck squamous cell carcinoma. Clin Cancer Res 13(19): 5663-5664, 2007. (Pubitemid 47583889)
    • (2007) Clinical Cancer Research , vol.13 , Issue.19 , pp. 5663-5664
    • Ferris, R.L.1    Grandis, J.R.2
  • 25
    • 31044448178 scopus 로고    scopus 로고
    • Mutant human tumor suppressor p53 modulates the activation of mitogen-activated protein kinase and nuclear factor-κB, but not c-Jun N-terminal kinase and activated protein-1
    • Gulati AP, Yang YM, Harter D, Mukhopadhyay A, Aggarwal BB, Benzil DL, Whysner J, Albino AP, Murali R and Jhanwar-Uniyal M: Mutant human tumor suppressor p53 modulates the activation of mitogen-activated protein kinase and nuclear factor-κB, but not c-Jun N-terminal kinase and activated protein-1. Mol Carciriog 45(1): 26-37, 2006.
    • (2006) Mol Carciriog , vol.45 , Issue.1 , pp. 26-37
    • Gulati, A.P.1    Yang, Y.M.2    Harter, D.3    Mukhopadhyay, A.4    Aggarwal, B.B.5    Benzil, D.L.6    Whysner, J.7    Albino, A.P.8    Murali, R.9    Jhanwar-Uniyal, M.10
  • 27
    • 34547131815 scopus 로고    scopus 로고
    • Cross-talks between cyclooxygenase-2 and tumor suppressor protein p53: Balancing life and death during inflammatory stress and carcinogenesis
    • de Moraes E, Dar NA, de Moura Gallo CV and Hainaut P: Cross-talks between cyclooxygenase-2 and tumor suppressor protein p53: Balancing life and death during inflammatory stress and carcinogenesis. Int J Cancer 121(5): 929-937, 2007.
    • (2007) Int J Cancer , vol.121 , Issue.5 , pp. 929-937
    • De Moraes, E.1    Dar, N.A.2    De Moura Gallo, C.V.3    Hainaut, P.4
  • 29
    • 0023925008 scopus 로고
    • Sequential development of aneuploidy, keratin modifications, and γ-glutamyltransferase expression in mouse skin papillomas
    • Aldaz CM, Conti CJ, Larcher F, Trono D, Roop DR, Chesner J, Whitehead T and Slaga TJ: Sequential development of aneuploidy, keratin modifications, and gamma-glutamyltransferase expression in mouse skin papillomas. Cancer Res 48(11): 3253-3257, 1988. (Pubitemid 18141925)
    • (1988) Cancer Research , vol.48 , Issue.11 , pp. 3253-3257
    • Aldaz, C.M.1    Conti, C.J.2    Larcher, F.3    Trono, D.4    Roop, D.R.5    Chesner, J.6    Whitehead, T.7    Slaga, T.J.8
  • 30
    • 0023678259 scopus 로고
    • Cytogenetic profile of mouse skin tumors induced by the viral Harvey-ras gene
    • Aldaz CM, Conti CJ, Yuspa SH and Slaga TJ: Cytogenetic profile of mouse skin tumors induced by the viral Harvey-ras gene. Carcinogenesis 9(8): 1503-1505, 1988.
    • (1988) Carcinogenesis , vol.9 , Issue.8 , pp. 1503-1505
    • Aldaz, C.M.1    Conti, C.J.2    Yuspa, S.H.3    Slaga, T.J.4
  • 31
    • 42749084082 scopus 로고    scopus 로고
    • The impact of p53 and p73 on aneuploidy and cancer
    • Tomasini R, Mak TW and Melino G: The impact of p53 and p73 on aneuploidy and cancer. Trends Cell Biol 18(5): 244-252, 2008.
    • (2008) Trends Cell Biol , vol.18 , Issue.5 , pp. 244-252
    • Tomasini, R.1    Mak, T.W.2    Melino, G.3
  • 32
    • 27144540976 scopus 로고    scopus 로고
    • Centrosome amplification, chromosome instability and cancer development
    • DOI 10.1016/j.canlet.2004.12.028, PII S0304383504009887
    • Fukasawa K: Centrosome amplification, chromosome instability and cancer development. Cancer Lett 230(1): 6-19, 2005. (Pubitemid 41506955)
    • (2005) Cancer Letters , vol.230 , Issue.1 , pp. 6-19
    • Fukasawa, K.1
  • 33
    • 0034004680 scopus 로고    scopus 로고
    • P53 mutation and mitotic infidelity
    • Tarapore P and Fukasawa K: p53 mutation and mitotic infidelity. Cancer Invest 18(2): 148-155, 2000.
    • (2000) Cancer Invest , vol.18 , Issue.2 , pp. 148-155
    • Tarapore, P.1    Fukasawa, K.2
  • 35
    • 33645285881 scopus 로고    scopus 로고
    • Is the loss of pRb essential for mouse skin carcinogenesis?
    • Ruiz S, Santos M and Paramio JM: Is the loss of pRb essential for mouse skin carcinogenesis? Cell Cycle 5(6): 625-629, 2006.
    • (2006) Cell Cycle , vol.5 , Issue.6 , pp. 625-629
    • Ruiz, S.1    Santos, M.2    Paramio, J.M.3
  • 38
    • 33748286796 scopus 로고    scopus 로고
    • A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
    • Carter SL, Eklund AC, Kohane IS, Harris LN and Szallasi Z: A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers. Nat Genet 38(9): 1043-1048, 2006.
    • (2006) Nat Genet , vol.38 , Issue.9 , pp. 1043-1048
    • Carter, S.L.1    Eklund, A.C.2    Kohane, I.S.3    Harris, L.N.4    Szallasi, Z.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.