Synthesis and preliminary in vitro biological evaluation of 4-[(4-hydroxyphenyl)sulfanyl]but-3-en-2-one, a 4-mercaptophenol derivative designed as a novel bifunctional antimelanoma agent

Journal of Medicinal Chemistry

Volumn 52, Issue 15, 2009, Pages 4973-4976

  Ruzza, Paolo ^a   Rosato, Antonio ^b,c   Nassi, Alberto ^b   Rondina, Maria ^b   Zorzin, Matteo ^a   Rossi, Carlo Riccardo ^b,c   Floreani, Maura ^b   Quintieri, Luigi ^b  

^a CNR   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 [(4 HYDROXYPHENYL)SULFANYL]BUT 3 EN ONE; 4 MERCAPTOPHENOL DERIVATIVE; ANTINEOPLASTIC AGENT; CARBONYL DERIVATIVE; GLUTATHIONE; MONOPHENOL MONOOXYGENASE; PHENOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME SUBSTRATE; IN VITRO STUDY; ISOMER; ISOMERISM; MELANOMA B16; MELANOMA CELL; NONHUMAN; PH;

ANIMALS; ANTINEOPLASTIC AGENTS; GLUTATHIONE; HYDROGEN-ION CONCENTRATION; MELANOMA, EXPERIMENTAL; MICE; MONOPHENOL MONOOXYGENASE; OXIDATION-REDUCTION; PHENYLBUTYRATES; SULFHYDRYL COMPOUNDS;

EID: 68549083584     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm900642j     Document Type: Article

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