Aminophylline (a theophylline-ethylenediamine complex) blocks ethanol behavioral effects in mice

Behavioural Pharmacology

Volumn 20, Issue 4, 2009, Pages 297-302

  Soares, Paula Matias ^a   Patrocínio, Manoel Cláudio Azevedo ^a   Assreuy, Ana Maria S ^a   Siqueira, Rômulo C L ^a   Lima, Natália Martins ^b   Arruda, Marta De Oliveira V ^a   De Souza Escudeiro, Sarah ^a   De Carvalho, Krishnamurti Moraes ^a   Sousa, Francisca Cléa Florenço ^b   Viana, Glauce Socorro Barros ^b   Vasconcelos, Silvĝnia Maria Mendes ^a,b  

^a STATE UNIVERSITY OF CEARÁ   (Brazil)

^b FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

Adenosine; Aminophylline; Behavioral models; Chronic ethanol; Methylxanthines

Indexed keywords

ALCOHOL; AMINOPHYLLINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; LOCOMOTION; MALE; MOUSE; MUSCLE RELAXATION; NONHUMAN; OPEN FIELD TEST; ROTAROD TEST; SIGNAL TRANSDUCTION;

ADMINISTRATION, ORAL; AMINOPHYLLINE; ANIMALS; BEHAVIOR, ANIMAL; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DRUG INTERACTIONS; ETHANOL; HINDLIMB SUSPENSION; INJECTIONS, INTRAPERITONEAL; MALE; MICE; MOTOR ACTIVITY; POSTURAL BALANCE; RECEPTORS, PURINERGIC P1;

EID: 68449091989     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.FBP.0000358355.88022.fa     Document Type: Article

References (44)

1. Archer J (1973). Tests for emotionality in rats and mice: a review. Anim Behav 21:205-235.
2. 2receptors. Alcohol Clin Exp Res 28:1308-1316.
3. Batista LC, Prediger RDS, Morato GS, Takahashi RN (2005). Blockade of adenosine and dopamine receptors inhibits the development of rapidtolerance to ethanol in mice. Psychopharmacology 181:714-721.
4. Boerngen-Lacerda R, Souza-Formigoni ML (2000). Does theincrease in locomotion induced by ethanol indicate its stimulant oranxiolytic properties? Pharmacol Biochem Behav 67:225-232.
5. Cohen C, Perrault G, Sanger DJ (1999). Effects of D[1] dopamine receptor agonists on oral ethanolself-administration in rats: comparison with their efficacy toproduce grooming and hyperactivity. Psychopharmacology 142:102-110.
6. Connole L, Harkin A, Maginn M (2004). Adenosine A, receptor blockade mimics caffeine's attenuation ofethanol-induced motor incoordination. Basic Clin PharmacolToxicol 95:299-304.
7. Cryan JF, Mombereau C, Vassout A (2005). The tail suspension test as a model for assessingantidepressant activity: review of pharmacological and geneticstudies in mice. Neurosci Biobehav Rev 29:571-625.
8. Cunha RA (2001). Adenosine as a neuromodulator and as a homeostaticregulator in the nervous systems: different roles, different sourcesand different receptors. Neurochem Int 38:107-125.
9. Dahchour A, De Witte P (2000). Ethanol and amino acids in thecentral nervous system: assessment of the pharmacological actions ofacamprosate. Prog Neurobiol 60:343-362.
10. Dar MS (1990). Central adenosinergic system involvement in ethanol-inducedmotor incoordination in mice. J Pharmacol Exp Ther 255:1202-1209.
11. Dar MS (1993). Brain adenosinergicmodulation of acute ethanol-induced motor impairment. AlcoholAlcohol Suppl 2:425-429.
12. 1adenosinergic receptor. Brain Res Bull 55:513-520.
13. Diamond I, Gordon AS (1997). Cellular and molecular neuroscience of alcoholism. Physiol Rev 77:1-20.
14. Diana M, Brodie M, Muntoni A, Puddu MC, Pillolla G, Steffensen S, et al. (2003). Enduring effects of chronic ethanol in the CNS: basis foralcoholism. Alcohol Clin Exp Res 27:354-361.
15. Dunham NW, Miya TS (1957). A note on a simple apparatus for detectingneurological deficits in rats and mice. J Am Pharm Assoc 46:208-209.
16. 2A receptor knockoutmice. Br J Pharmacol 134:68-77.
17. 2A receptorblockade. Neuropharmacology 45:977-985.
18. Ferré S, Fredholm BB, Morelli M, Popoli P, Fuxe K (1997). Adenosine-dopaminereceptor-receptor interactions as an integrative mechanism in thebasal ganglia. Trends Neurosci 20:482-487.
19. FigueiraI (2002). Ethanol and alcoholic beverages: can the pharmacologicalactivity of the alcohol explain the diversity of effect in thedifferent systems? Revista da Faculdade de Medicina daUniversidade de Lisboa 7:165-171.
20. Fillmore MT (2003). Alcohol tolerance in humans in enhanced by prior caffeine antagonism of alcohol-induced impairment. Exp Clin Psychopharmacol 11:9-17.
21. 2 dopamine receptors in rat striatum. Brain Res MolBrain Res 14:186-195.
22. Fleming M, Mihic SJ, Harris RA (2003). Ethanol. In: Hardman JG, Limbird LE, Gilman AG, editors. Goodman & Gilman - The pharmacological basis of therapeutics. 10th ed. Brazil: McGraw-Hill; pp. 325-337.
23. Fredholm BB, Ijzerman AP, Jacobson KA, Klotz K, Linden J (2001). International Union of Pharmacology XXV - Nomenclature and classification of adenosinereceptors. Pharmacol Rev 53:527-552.
24. 2A receptors in anxiolytic, locomotor and motivational properties of ethanol in mice. GenesBrain Behav 7:887-898.
25. Areceptor channels by anticonvulsant and convulsant drugs and byphosphorylation. Epilepsy Res Suppl 9:265-277.
26. Nakano J (2006). Aminophylline suppresses the release of chemicalmediators in treatment of acute asthma. Respir Med 100:542-550.
27. Narimatsu E, Aoki M (2000). Transientdepression of excitatory synaptic transmission induced by adenosineuptake inhibition in rat hippocampal slices. Brain Res 862:284-287.
28. Nevo I, Hamon M (1995). Neurotransmistter and neuromodulatory mechanisms involved in alcohol abuse and alcoholism. Neurochem Int 26:305-336.
29. 2dopaminedependent activation of Fos in the striatopallidal pathway. Neuroscience 68:721-728.
30. Prediger RDS, Batista LC, Takahashi RN (2004). Adenosine A1 receptors modulate theanxiolytic-like effect of ethanol in the elevated plus-maze in mice. Eur J Pharmacol 499:147-154.
31. Prediger RDS, da Silva GE, Batista LC, Bittencourt AL, Takahashi RN (2006). Activation ofadenosine A, receptors reduces anxiety-like behavior during acuteethanol withdrawal (hangover) in mice. Neuropsychopharmacology 31:2210-2220.
32. Rang HP, Dale MM, Ritter JM, Flower RJ (2007). Rang & Dale farmacologia. 6thed. Brazil: Elsevier.
33. Ribeiro JA, Sebastiāo AM, DeMendonça A (2002). Adenosine receptors in the nervous system: pathophysiological implications. Prog Neurobiol 68:377-392.
34. Spinetta MJ, Woodlee MT, Feinberg LM, Stroud C, Schallert K, Cormack LK, Schallert T (2008). Alcohol-inducedretrograde memory impairment in rats: prevention by caffeine. Psychopharmacology 201:361-371.
35. Steru L, Chermat R, Thierry B, Simon P (1985). Tail suspension test: a new method forscreening antidepressants in mice. Psychopharmacology 85:367-370.
36. Taberner P, Badaway D (1993). Advances inbiomedical alcoholism research. Oxford: Pergamon Press.
37. Theile JW, Morikawa H, Gonzales RA, Morrisett RA (2008). Ethanol enhancesGABAergic transmission onto dopamine neurons in the ventral area ofthe rat. Alcohol Clin Exp Res 32:1040-1048.
38. 2Areceptor antagonist 3,7-dimethyl-propargylxanthine on anxiety-likeand depression-like behavior and alcohol consumption in Wistar rats. Alcohol Clin Exp Res 31:1302-1307.
39. Tohdoh Y, Narimatsu E, Kawamata M, Namiki A (2000). The involvement ofadenosine neuromodulation in pentobarbital-induced field excitatorypostsynaptic potentials depression in rat hippocampal slices. Anesth Analg 91:1537-1541.
40. Vasconcelos SMM (2001). Behavioral, neurochemical and biochemical effects of ethanol inrodents in the presence and absence of dopaminergic, glutamatergicand opioid. [PhD. Thesis in Pharmacology]. UFC: Fortaleza/Brazil.
41. Vasconcelos SMM, Macêdo DS, Lima LO, Sousa FCF, FontelesMMF, Viana GSB (2003). Effect of one-week ethanol treatment onmonoamine levels and dopaminergic receptors in rat striatum. BrazJ Med Biol Res 36:503-509.
42. Vasconcelos SMM, Cavalcante RA, Aguiar LM, Sousa FC, Fonteles MM, Viana GS (2004). Effects ofchronic ethanol treatment on monoamine levels in rat hippocampus and striatum. Braz J Med Biol Res 37:1839-1946.
43. Williams M (1995). Purinoceptors in central nervous systemfunction. In: Bloom FE, Kupfer D, editors. Psychopharmacology. Thefourth generation of progress. New York: Raven Press; pp. 643-655.
44. Xiao C, Zhou C, Li K, Davies DL, Ye JH (2008). Purinergictype 2 receptors at GABAergic synapses on ventral tegmental areadopamine neurons are targets for ethanol action. J Pharmacol ExpTher 327:196-205.