Isolation of cobalt hyper-resistant mutants of Saccharomyces cerevisiae by in vivo evolutionary engineering approach

Journal of Biotechnology

Volumn 143, Issue 2, 2009, Pages 130-138

  Çakar, Z Petek ^a   Alkim, Ceren ^a   Turanli, Burcu ^a   Tokman, Nilgün ^a   Akman, Süleyman ^a   Sarikaya, Mehmet ^a,b   Tamerler, Candan ^a,b   Benbadis, Laurent ^c,d,e   François, Jean M ^c,d,e  

^a ISTANBUL TECHNICAL UNIVERSITY   (Turkey)

^b UNIVERSITY OF WASHINGTON   (United States)

^c INSA   (France)

^d UMR792 INGÉNIERIE DES SYSTÈMES BIOLOGIQUES ET DES PROCÉDÉS   (France)

^e CNRS   (France)

Author keywords

Cobalt resistance; Evolutionary engineering; Population heterogeneity; Saccharomyces cerevisiae

Indexed keywords

BIOLOGICAL ACTIVITIES; CELLULAR RESPONSE; CHROMIUM IONS; COBALT CONCENTRATION; COBALT CONTENT; CONTINUOUS EXPOSURE; EVOLUTIONARY ENGINEERING; HEAT-SHOCK; IN-VIVO; LIVING SYSTEMS; POPULATION HETEROGENEITY; PULSE EXPOSURE; RESISTANT CELLS; RESISTANT MUTANTS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE CELLS; STRESS LEVELS; SURVIVAL RATE; WILD TYPES;

CELL CULTURE; CELL MEMBRANES; CELL PROLIFERATION; CHROMIUM; ENGINEERING; HEAT RESISTANCE; HYDROGEN; HYDROGEN PEROXIDE; INDUSTRIAL APPLICATIONS; MAGNETIC PROPERTIES; MANGANESE; METAL IONS; POPULATION STATISTICS; STRAIN; YEAST; ZINC;

COBALT;

CHROMIUM; COBALT; COBALT CHLORIDE; COPPER; MANGANESE; NICKEL; ZINC;

ARTICLE; CHEMICAL STRESS; CONTROLLED STUDY; CROSS RESISTANCE; EVOLUTIONARY ADAPTATION; FUNGAL STRAIN; FUNGAL VIABILITY; FUNGUS IDENTIFICATION; HEAT STRESS; METAL TOLERANCE; NONHUMAN; OSMOTIC STRESS; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; STRAIN DIFFERENCE; SURVIVAL RATE;

CELL SURVIVAL; COBALT; DIRECTED MOLECULAR EVOLUTION; DRUG RESISTANCE, FUNGAL; HOT TEMPERATURE; HYDROGEN PEROXIDE; MUTATION; NICKEL; SACCHAROMYCES CEREVISIAE; STRESS, PHYSIOLOGICAL;

SACCHAROMYCES CEREVISIAE;

EID: 68349157532     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2009.06.024     Document Type: Article

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