메뉴 건너뛰기




Volumn 14, Issue 2, 2009, Pages 138-148

Comparison of single pot and multiphase granulation. Part 1: Effect of the high shear granulator on granule properties according to the drug substance and its concentration

Author keywords

Comprimability; Dissolution kinetics; Experimental design single pot; Formulation; Granule and tablets properties; High shear wet granulation

Indexed keywords

ARTICLE; COMPARATIVE STUDY; DRUG FORMULATION; DRUG GRANULATION; DRUG GRANULE; DRUG MIXTURE; DRUG SOLUBILITY; KINETICS; PARTICLE SIZE; PILOT STUDY; PRIORITY JOURNAL; CHEMISTRY; EQUIPMENT DESIGN; INSTRUMENTATION; METHODOLOGY; POROSITY; SOLUBILITY; TABLET; TENSILE STRENGTH;

EID: 68349138600     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.1080/10837450802588926     Document Type: Article
Times cited : (4)

References (39)
  • 1
    • 0023225538 scopus 로고
    • Granulation, a review on pharmaceutical wet-granulation
    • Kristensen HG, Schaefer T. Granulation, a review on pharmaceutical wet-granulation. Drug Dev. Ind. Pharm. 1987;13(4-5):803-873.
    • (1987) Drug Dev. Ind. Pharm. , vol.13 , Issue.4-5 , pp. 803-873
    • Kristensen, H.G.1    Schaefer, T.2
  • 2
    • 8844227468 scopus 로고    scopus 로고
    • Comparing diferent granulation techniques
    • Stahl H. Comparing diferent granulation techniques. Pharm. Technol. Eur. 2004;11:23-33.
    • (2004) Pharm. Technol. Eur. , vol.11 , pp. 23-33
    • Stahl, H.1
  • 3
    • 0024563288 scopus 로고
    • Granulation à l'aide d'un granulateur-séchoir à grande vitesse
    • Gaillard C, Chulia D, Jeannin C, Ozil P, Paschos S. Granulation à l'aide d'un granulateur-séchoir à grande vitesse. Pharm. Acta Helv. 1989;64(5-6):168-176.
    • (1989) Pharm. Acta Helv. , vol.64 , Issue.5-6 , pp. 168-176
    • Gaillard, C.1    Chulia, D.2    Jeannin, C.3    Ozil, P.4    Paschos, S.5
  • 4
    • 0025606460 scopus 로고
    • Etude par plan d'expérience de l'infuence de trois paramètres de fabrication sur la qualité de grains obtenus en turbosphère
    • André F, Bouiller B, Adams S, Bagnaro M, Becourt P, Guyot JC. Etude par plan d'expérience de l'infuence de trois paramètres de fabrication sur la qualité de grains obtenus en turbosphère. STP Pharma Sci. 1990;6(10):723-727.
    • (1990) STP Pharma Sci. , vol.6 , Issue.10 , pp. 723-727
    • André, F.1    Bouiller, B.2    Adams, S.3    Bagnaro, M.4    Becourt, P.5    Guyot, J.C.6
  • 5
    • 0040625867 scopus 로고
    • Rationale for selection of a single-pot manufacturing process using microwave/vacuum drying
    • Robin P, Luciano LJ, Prealswig DM. Rationale for selection of a single-pot manufacturing process using microwave/vacuum drying. Pharm. Technol. 1994;18(5):28-36.
    • (1994) Pharm. Technol. , vol.18 , Issue.5 , pp. 28-36
    • Robin, P.1    Luciano, L.J.2    Prealswig, D.M.3
  • 6
    • 33745620470 scopus 로고    scopus 로고
    • Multiphase versus single pot granulation process: Infuence of process and granulation parameters on granules properties
    • Giry K, Genty M, Viana M, Wüthrich P, Chulia D. Multiphase versus single pot granulation process: infuence of process and granulation parameters on granules properties. Drug Dev. Ind. Pharm. 2006;32(5):509-530.
    • (2006) Drug Dev. Ind. Pharm. , vol.32 , Issue.5 , pp. 509-530
    • Giry, K.1    Genty, M.2    Viana, M.3    Wüthrich, P.4    Chulia, D.5
  • 7
    • 33745630298 scopus 로고
    • Traitement mécanique des solides dans les mélangeurs à turbine - infuence de la géométrie d'agitation
    • Le Lan A. Traitement mécanique des solides dans les mélangeurs à turbine - infuence de la géométrie d'agitation. Int. Sympos. Mixing. 1978:D2-1-D2-30.
    • (1978) Int. Sympos. Mixing.
    • Le Lan, A.1
  • 9
    • 0027291693 scopus 로고
    • Scaling-up of wet granulation. A statistical methodology
    • Wehrlé P, Nobelis Ph, Cuiné A, Stamm A. Scaling-up of wet granulation. A statistical methodology. Drug Dev. Ind. Pharm. 1993;19(16):1983-1997.
    • (1993) Drug Dev. Ind. Pharm. , vol.19 , Issue.16 , pp. 1983-1997
    • Wehrlé, P.1    Ph, N.2    Cuiné, A.3    Stamm, A.4
  • 10
    • 0015765986 scopus 로고
    • Te infuence on pharmaceutical granulation of the type and capacity of mixers
    • Hunter BN, Ganderton D. Te infuence on pharmaceutical granulation of the type and capacity of mixers. J. Pharm. Pharmacol. 1973;25(Suppl.):71P-78.
    • (1973) J. Pharm. Pharmacol. , Issue.25 SUPPL.
    • Hunter, B.N.1    Ganderton, D.2
  • 12
    • 0040279872 scopus 로고
    • Efect of impeller and chopper design on the granulation in a high speed mixer
    • Holm P. Efect of impeller and chopper design on the granulation in a high speed mixer. Drug Dev. Ind. Pharm. 1987;13(9-11):1675-1701.
    • (1987) Drug Dev. Ind. Pharm. , vol.13 , Issue.9-11 , pp. 1675-1701
    • Holm, P.1
  • 13
    • 2342456453 scopus 로고    scopus 로고
    • On control of particle size distribution in granulation high-shear mixers
    • Bardin M, Knight PC, Seville JPK. On control of particle size distribution in granulation high-shear mixers. Powder Technol. 2004;140:169-175.
    • (2004) Powder Technol. , vol.140 , pp. 169-175
    • Bardin, M.1    Knight, P.C.2    Seville, J.P.K.3
  • 14
    • 0035823007 scopus 로고    scopus 로고
    • Prediction of the impeller torque in high shear powder mixers
    • Knight PC, Seville JPK, Wellm AB, Instone T. Prediction of the impeller torque in high shear powder mixers. Chem. Eng. Sci. 2001;56(15):4457-4471.
    • (2001) Chem. Eng. Sci. , vol.56 , Issue.15 , pp. 4457-4471
    • Knight, P.C.1    Seville, J.P.K.2    Wellm, A.B.3    Instone, T.4
  • 20
    • 33846272147 scopus 로고    scopus 로고
    • Comparison of the efects of diferent drying techniques on properties of granules and tablets made on a production scale
    • Hegedös A, Pintye-Hódi K. Comparison of the efects of diferent drying techniques on properties of granules and tablets made on a production scale. Int. J. Pharm. 2007;330(1-2):99-104.
    • (2007) Int. J. Pharm. , vol.330 , Issue.1-2 , pp. 99-104
    • Hegedös, A.1    Pintye-Hódi, K.2
  • 21
    • 0037139413 scopus 로고    scopus 로고
    • Preparation, characterisation and tableting properties of a new cellulose-based pharmaceutical aid
    • Kumar V, Reus-Medina ML, Yang D. Preparation, characterisation and tableting properties of a new cellulose-based pharmaceutical aid. Int. J. Pharm. 2002;235(2):129-140.
    • (2002) Int. J. Pharm. , vol.235 , Issue.2 , pp. 129-140
    • Kumar, V.1    Reus-Medina, M.L.2    Yang, D.3
  • 22
    • 0004251767 scopus 로고    scopus 로고
    • 5th ed. Strasbourg
    • European Pharmacopea. 5th ed. Strasbourg; 2007.
    • (2007) European Pharmacopea
  • 23
    • 0000496231 scopus 로고
    • Evaluating fow properties of solids
    • Carr RL. Evaluating fow properties of solids. Chem. Eng. 1965;18:163-168.
    • (1965) Chem. Eng. , vol.18 , pp. 163-168
    • Carr, R.L.1
  • 24
    • 0035305620 scopus 로고    scopus 로고
    • Validation of a new pertinent packing coefcient to estimate fow properties of pharmaceutical powders at a very early stage, by comparison with mercury intrusion and classical fowability methods
    • Gabaude C, Gautier JC, Saudemon Ph, Chulia D. Validation of a new pertinent packing coefcient to estimate fow properties of pharmaceutical powders at a very early stage, by comparison with mercury intrusion and classical fowability methods. J. Mat. Sci. 2001;36:1763-1773.
    • (2001) J. Mat. Sci. , vol.36 , pp. 1763-1773
    • Gabaude, C.1    Gautier, J.C.2    Ph, S.3    Chulia, D.4
  • 25
    • 0141489133 scopus 로고    scopus 로고
    • Te packing coefcient: A suitable parameter to assess the fow properties of powders
    • Viana M, Gabaude-Renou CMD, Pontier C, Chulia D. Te packing coefcient: a suitable parameter to assess the fow properties of powders. Kona. 2001;19:85-93.
    • (2001) Kona. , vol.19 , pp. 85-93
    • Viana, M.1    Gabaude-Renou, C.M.D.2    Pontier, C.3    Chulia, D.4
  • 26
    • 0037398748 scopus 로고    scopus 로고
    • Energetic yields in apatic calcium phosphates compression: Infuence of the Ca/P molar ratio
    • Pontier C, Viana M, Champion E, Bernache-Assolant D, Chulia D. Energetic yields in apatic calcium phosphates compression: infuence of the Ca/P molar ratio. Polym. Int. 2003;52:625-628.
    • (2003) Polym. Int. , vol.52 , pp. 625-628
    • Pontier, C.1    Viana, M.2    Champion, E.3    Bernache-Assolant, D.4    Chulia, D.5
  • 27
    • 18744376589 scopus 로고    scopus 로고
    • Powder functionality test: A methodology for rheological and mechanical characterization
    • Viana M, Ribet J, Rodriguez F, Chulia D. Powder functionality test: a methodology for rheological and mechanical characterization. Pharm. Dev. Technol. 2005;10(2):327-338.
    • (2005) Pharm. Dev. Technol. , vol.10 , Issue.2 , pp. 327-338
    • Viana, M.1    Ribet, J.2    Rodriguez, F.3    Chulia, D.4
  • 29
    • 0000292691 scopus 로고
    • Density-pressure relationship in powder compaction
    • Heckel RW. Density-pressure relationship in powder compaction. Trans. Metall. Soc. AIME. 1961;221:671-675.
    • (1961) Trans. Metall. Soc. AIME. , vol.221 , pp. 671-675
    • Heckel, R.W.1
  • 30
    • 0001685520 scopus 로고
    • Méthode rap-ide de détermination du comportement à la compression pour des études de préformulation
    • Humbert-Droz P, Mordier D, Doelker E. Méthode rap-ide de détermination du comportement à la compression pour des études de préformulation. Pharm. Acta Helv. 1982;57:136-143.
    • (1982) Pharm. Acta Helv. , vol.57 , pp. 136-143
    • Humbert-Droz, P.1    Mordier, D.2    Doelker, E.3
  • 31
    • 0021873527 scopus 로고
    • Te efect of punch velocity on the compaction of a variety of materials
    • Roberts RJ, Rowe RC. Te efect of punch velocity on the compaction of a variety of materials. J. Pharm. Pharmacol. 1985;37:377-384.
    • (1985) J. Pharm. Pharmacol. , vol.37 , pp. 377-384
    • Roberts, R.J.1    Rowe, R.C.2
  • 32
    • 0032809140 scopus 로고    scopus 로고
    • Efects of true density, compacted mass, compression speed, and punch deformation on the mean yield pressure
    • Gabaude CMD, Guillot M, Gautier JC, Saudemon P, Chulia D. Efects of true density, compacted mass, compression speed, and punch deformation on the mean yield pressure. J. Pharm. Sci. 1999;88(7):725-730.
    • (1999) J. Pharm. Sci. , vol.88 , Issue.7 , pp. 725-730
    • Gabaude, C.M.D.1    Guillot, M.2    Gautier, J.C.3    Saudemon, P.4    Chulia, D.5
  • 33
  • 34
    • 0014785506 scopus 로고
    • Determination of tablets strength by the diametral-compression test
    • Fell JT, Newton JM. Determination of tablets strength by the diametral-compression test. J. Pharm. Sci. 1970;59(5):688-691.
    • (1970) J. Pharm. Sci. , vol.59 , Issue.5 , pp. 688-691
    • Fell, J.T.1    Newton, J.M.2
  • 35
    • 3843107053 scopus 로고    scopus 로고
    • Analysis of tablet compaction. I. Characterization of mechanical behaviour of powder and powder/tooling friction
    • Cunningham JC, Sinka IC, Zavaliangos A. Analysis of tablet compaction. I. Characterization of mechanical behaviour of powder and powder/tooling friction. J. Pharm. Sci. 2004;93(8):2022-2039.
    • (2004) J. Pharm. Sci. , vol.93 , Issue.8 , pp. 2022-2039
    • Cunningham, J.C.1    Sinka, I.C.2    Zavaliangos, A.3
  • 38
    • 0035073301 scopus 로고    scopus 로고
    • Modelling and comparison of dissolution profles
    • Costa P, Sousa Lobo JM. Modelling and comparison of dissolution profles. Eur. J. Pharm. Sci. 2001;13(2):123-133.
    • (2001) Eur. J. Pharm. Sci. , vol.13 , Issue.2 , pp. 123-133
    • Costa, P.1    Sousa Lobo, J.M.2
  • 39
    • 2342652446 scopus 로고    scopus 로고
    • Mathematical comparison of dissolution profles
    • Moore W, Flanner HH. Mathematical comparison of dissolution profles. Pharm. Technol. 1996;20:64-74.
    • (1996) Pharm. Technol. , vol.20 , pp. 64-74
    • Moore, W.1    Flanner, H.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.