Validation of a new pertinent packing coefficient to estimate flow properties of pharmaceutical powders at a very early development stage, by comparison with mercury intrusion and classical flowability methods

Journal of Materials Science

Volumn 36, Issue 7, 2001, Pages 1763-1773

  Gabaude, C M D ^a   Gautier, J C ^a   Saudemon, P ^a   Chulia, D ^b  

^a SANOFI   (France)

^b UNIVERSITY OF LIMOGES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG PRODUCTS; ELEMENTARY PARTICLES; GRANULAR MATERIALS; MERCURY (METAL); SHEAR FLOW;

PARTICLE GRANULOMETRY; PHARMACEUTICAL POWDERS;

POWDERS;

EID: 0035305620     PISSN: 00222461     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1017528809955     Document Type: Article

References (30)

1. M. DELEUIL, STP Pharma 8 (1987) 668.
2. D. DUCHÊNE, ibid. 3 (1987) 794.
3. C. THOMAS and Y. POURCELOT, Drug Dev. Ind. Pharm. 19 (1993) 1947.
4. R. L. CARR, Chem. Eng. 18 (1965) 163.
5. idem., British Chem. Eng. 15 (1970) 1541.
6. H. G. BRITTAIN, S. J. BOGDANOWICH, D. E. BUGAY, J. DE VINCENTIS, G. LEWEN and A. W. NEWMAN, Pharm. Res. 8 (1991) 963.
7. J. C. GUYOT, STP Pharma 7 (1978) 551.
8. A. DELACOURTE-THIBAUT, J. C. GAYOT and M. TRAISNEL, ibid. 11 (1982) 131.
9. D. CHULIA, STP Pharma Pr. 1 (1991) 473.
10. P. YORK, J. Pharm. Sci. 64 (1975) 1216.
11. H. NYQVIST, A. BRODIN and L. NILSSON, Acta Pharm. Suec. 17 (1980) 215.
12. R. HO, D. F. BAGSTER and M. J. CROOKS, Drug Dev. Ind. Pharm. 3 (1977) 475.
13. C. MBALI-PEMBA, Fonctionnalité des matériaux particulaires: application à la comprimabilité des lactoses 1994; Université de Limoges, France;
14. A. M. JUPPO, L. KERVINEN, J. K. YLIRUUSI and E. KRISTOFFERSSON, J. Pharm. Pharmacol. 47 (1995) 543.
15. D. CHULIA, Rhéologie des poudres et préformulation. Un modèle d'étude : l'acide acétylsalicylique 1981; Grenoble I, France;
16. M. V. VELASCO ANTEQUERA, A. MUNOZ, M. C. MONEDERO and M. R. JIMENEZ-CASTELLANOS, J. Pharm. Belg. 48 (1993) 365.
17. H. NYQVIST, Acta Pharm. Suec. 19 (1982) 413.
18. P. YORK, J. Pharm. Pharmacol. 30 (1978) 6.
19. R. W. HECKEL, Trans. Met. Soc. AIME 221 (1961) 671.
20. C. M. D. GABAUDE, M. GUILLOT, J. C. GAUTIER, PH. SAUDEMON and D. CHULIA, J. Pharm. Sci.. 88 (1999) 725.
21. P. J. DEES, Powder Technol. 29 (1981) 187.
22. E. W. WASHBURN, The Physical Review 17 (1921) 273.
23. A. M. MARKS and J. J. SCIARRA, J. Pharm. Sci. 57 (1968) 497.
24. E. GUERIN, P. TCHORELOFF, B. LECLERC, D. TANGUY, M. DELEUIL and G. COUARRAZE, Int. J. Pharm. 189 (1999) 91.
25. A. H. GERRITSEN and S. STEMERDING, Powder Technol. 27 (1980) 183.
26. A. W. JENIKE, Utah Engineers Experimental Station 1964.
27. J. R. JOHANSON, Bulk Solids Handling 12 (1992).
28. T. A. BELL, B. J. ENNIS and others, in Proceedings of the Reliable Flow of Particulate Solids I, Oslo, Norway, 1993.
29. I. WOUTERS, J. BOUSQUET and J. L. CHABOCHE, in Proceedings of the 2nd European Congress of Chemical Engineering, Montpellier, 1999.
30. C. COHARD, Y. GONTHIER, D. CHULIA and A. VERAIN, J. Pharm. Belg. 39 (1984) 209.