HSV-1 upregulates the ARE-binding protein tristetraprolin in a STAT1- and p38-dependent manner in mature dendritic cells

Immunobiology

Volumn 214, Issue 9-10, 2009, Pages 852-860

  Kummer, Mirko ^a   Prechtel, Alexander T ^a   Mühl Zürbes, Petra ^a   Turza, Nadine M ^a   Steinkasserer, Alexander ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

Dendritic cells; Herpes simplex virus type 1; TNF; Tristetraprolin

Indexed keywords

MESSENGER RNA; STAT1 PROTEIN; SYNAPTOPHYSIN; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR;

ARTICLE; CELL MATURATION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; UPREGULATION; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TITRATION; WESTERN BLOTTING;

CELLS, CULTURED; DENDRITIC CELLS; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RNA, MESSENGER; STAT1 TRANSCRIPTION FACTOR; TRISTETRAPROLIN; UP-REGULATION;

EID: 68349121584     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2009.06.011     Document Type: Article

References (29)

1. Aliprantis A.O., Yang R.B., Mark M.R., Suggett S., Devaux B., Radolf J.D., Klimpel G.R., Godowski P., and Zychlinsky A. Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science 285 (1999) 736-739
2. Atasoy U., Watson J., Patel D., and Keene J.D. ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. J. Cell Sci. 111 Pt 21 (1998) 3145-3156
3. Blackshear P.J. Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover. Biochem. Soc. Trans. 30 (2002) 945-952
4. Brennan C.M., and Steitz J.A. HuR and mRNA stability. Cell Mol. Life Sci. 58 (2001) 266-277
5. Brightbill H.D., Libraty D.H., Krutzik S.R., Yang R.B., Belisle J.T., Bleharski J.R., Maitland M., Norgard M.V., Plevy S.E., Smale S.T., Brennan P.J., Bloom B.R., Godowski P.J., and Modlin R.L. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 285 (1999) 732-736
6. Burns S., and Thrasher A.J. Dendritic cells: the bare bones of immunity. Curr. Biol. 14 (2004) R965-R967
7. Campbell J., Ciesielski C.J., Hunt A.E., Horwood N.J., Beech J.T., Hayes L.A., Denys A., Feldmann M., Brennan F.M., and Foxwell B.M. A novel mechanism for TNF-alpha regulation by p38 MAPK: involvement of NF-kappa B with implications for therapy in rheumatoid arthritis. J. Immunol. 173 (2004) 6928-6937
8. Cella M., Salio M., Sakakibara Y., Langen H., Julkunen I., and Lanzavecchia A. Maturation, activation, and protection of dendritic cells induced by double-stranded RNA. J. Exp. Med. 189 (1999) 821-829
9. Coffin R.S., MacLean A.R., Latchman D.S., and Brown S.M. Gene delivery to the central and peripheral nervous systems of mice using HSV1 ICP34.5 deletion mutant vectors. Gene Ther. 3 (1996) 886-891
10. Eisemann J., Muhl-Zurbes P., Steinkasserer A., and Kummer M. Infection of mature dendritic cells with herpes simplex virus type 1 interferes with the interferon signaling pathway. Immunobiology 212 (2008) 877-886
11. Everett R.D., Boutell C., and Orr A. Phenotype of a herpes simplex virus type 1 mutant that fails to express immediate-early regulatory protein ICP0. J. Virol. 78 (2004) 1763-1774
12. Fan X.C., and Steitz J.A. Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J. 17 (1998) 3448-3460
13. Goldsmith K., Chen W., Johnson D.C., and Hendricks R.L. Infected cell protein (ICP)47 enhances herpes simplex virus neurovirulence by blocking the CD8+ T cell response. J. Exp. Med. 187 (1998) 341-348
14. Hill A., Jugovic P., York I., Russ G., Bennink J., Yewdell J., Ploegh H., and Johnson D. Herpes simplex virus turns off the TAP to evade host immunity. Nature 375 (1995) 411-415
15. Kodukula P., Liu T., Rooijen N.V., Jager M.J., and Hendricks R.L. Macrophage control of herpes simplex virus type 1 replication in the peripheral nervous system. J. Immunol. 162 (1999) 2895-2905
16. Kruse M., Rosorius O., Kratzer F., Stelz G., Kuhnt C., Schuler G., Hauber J., and Steinkasserer A. Mature dendritic cells infected with herpes simplex virus type 1 exhibit inhibited T-cell stimulatory capacity. J. Virol. 74 (2000) 7127-7136
17. Kummer M., Turza N.M., Muhl-Zurbes P., Lechmann M., Boutell C., Coffin R.S., Everett R.D., Steinkasserer A., and Prechtel A.T. Herpes simplex virus type 1 induces CD83 degradation in mature dendritic cells with immediate-early kinetics via the cellular proteasome. J. Virol. 81 (2007) 6326-6338
18. Li J., Wasmuth S., Bauer D., Baehler H., Hennig M., and Heiligenhaus A. Subconjunctival antisense oligonucleotides targeting TNF-alpha influence immunopathology and viral replication in murine HSV-1 retinitis. Graefes Arch. Clin. Exp. Ophthalmol. 246 (2008) 1265-1273
19. Mikloska Z., Bosnjak L., and Cunningham A.L. Immature monocyte-derived dendritic cells are productively infected with herpes simplex virus type 1. J. Virol. 75 (2001) 5958-5964
20. Prechtel A.T., Turza N.M., Kobelt D.J., Eisemann J.I., Coffin R.S., McGrath Y., Hacker C., Ju X., Zenke M., and Steinkasserer A. Infection of mature dendritic cells with herpes simplex virus type 1 dramatically reduces lymphoid chemokine-mediated migration. J. Gen. Virol. 86 (2005) 1645-1657
21. Ridge J.P., Di R.F., and Matzinger P. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell. Nature 393 (1998) 474-478
22. Samady L., Costigliola E., MacCormac L., McGrath Y., Cleverley S., Lilley C.E., Smith J., Latchman D.S., Chain B., and Coffin R.S. Deletion of the virion host shutoff protein (vhs) from herpes simplex virus (HSV) relieves the viral block to dendritic cell activation: potential of vhs-HSV vectors for dendritic cell-mediated immunotherapy. J. Virol. 77 (2003) 3768-3776
23. Sauer I., Schaljo B., Vogl C., Gattermeier I., Kolbe T., Muller M., Blackshear P.J., and Kovarik P. Interferons limit inflammatory responses by induction of tristetraprolin. Blood 107 (2006) 4790-4797
24. Shaw G., and Kamen R. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46 (1986) 659-667
25. Smiley JR. Herpes simplex virus virion host shutoff protein: immune evasion mediated by a viral RNase?. J. Virol. 78 (2004) 1063-1068
26. Sodeik B., Ebersold M.W., and Helenius A. Microtubule-mediated transport of incoming herpes simplex virus 1 capsids to the nucleus. J. Cell Biol. 136 (1997) 1007-1021
27. Steinman R.M., and Banchereau J. Taking dendritic cells into medicine. Nature 449 (2007) 419-426
28. Taylor G.A., Carballo E., Lee D.M., Lai W.S., Thompson M.J., Patel D.D., Schenkman D.I., Gilkeson G.S., Broxmeyer H.E., Haynes B.F., and Blackshear P.J. A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. Immunity 4 (1996) 445-454
29. Whitley R.J., and Roizman B. Herpes simplex virus infections. Lancet 357 (2001) 1513-1518