메뉴 건너뛰기




Volumn 6, Issue 2, 2009, Pages 110-119

Long-term effect of metformin on metabolic parameters in the polycystic ovary syndrome

Author keywords

Cardiovascular risk factors; Metabolic syndrome; Metformin; Polycystic ovary syndrome

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; METFORMIN;

EID: 68349099934     PISSN: 14791641     EISSN: None     Source Type: Journal    
DOI: 10.1177/1479164109336050     Document Type: Article
Times cited : (26)

References (47)
  • 2
    • 0031773509 scopus 로고    scopus 로고
    • Prevalence of the polycystic ovary syndrome in unselected black and white women of the Southeastern United States: A prospective study
    • DOI 10.1210/jc.83.9.3078
    • Knochenhauer, ES, Key, TJ, Kahsar-Miller, M, Waggoner, W, Boots, LR, Azziz, R (1998) Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab 83: 3078-3082 (Pubitemid 28500937)
    • (1998) Journal of Clinical Endocrinology and Metabolism , vol.83 , Issue.9 , pp. 3078-3082
    • Knochenhauer, E.S.1    Key, T.J.2    Kahsar-Miller, M.3    Waggoner, W.4    Boots, L.R.5    Azziz, R.6
  • 3
    • 0032948363 scopus 로고    scopus 로고
    • Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: A prospective, controlled study in 254 affected women
    • DOI 10.1210/jc.84.1.165
    • Legro, RS, Kunselman, AR, Dodson, WC, Dunaif, A (1999) Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women. J Clin Endocrinol Metab 84: 165-169 (Pubitemid 29036695)
    • (1999) Journal of Clinical Endocrinology and Metabolism , vol.84 , Issue.1 , pp. 165-169
    • Legro, R.S.1    Kunselman, A.R.2    Dodson, W.C.3    Dunaif, A.4
  • 4
    • 0030960289 scopus 로고    scopus 로고
    • Role of hyperinsulinemia in the pathogenesis of the polycystic ovary syndrome, and its clinical implications
    • Nestler, JE (1997) Role of hyperinsulinemia in the pathogenesis of the polycystic ovary syndrome, and its clinical implications. Semin Reprod Endocrinol 15: 111-122
    • (1997) Semin Reprod Endocrinol , vol.15 , pp. 111-122
    • Nestler, J.E.1
  • 5
    • 0030783316 scopus 로고    scopus 로고
    • Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17 alpha activity and serum androgens
    • Nestler, JE, Jakubowicz, DJ (1997) Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17 alpha activity and serum androgens. J Clin Endocrinol Metab 82: 4075-4079
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 4075-4079
    • Nestler, J.E.1    Jakubowicz, D.J.2
  • 6
    • 0029796476 scopus 로고    scopus 로고
    • Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome
    • Nestler, JE, Jakubowicz, DJ (1996)Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome. N Engl J Med 335: 617-623
    • (1996) N Engl J Med , vol.335 , pp. 617-623
    • Nestler, J.E.1    Jakubowicz, D.J.2
  • 8
    • 0028899597 scopus 로고
    • Hyperandrogenic anovulation (PCOS): A unique disorder of insulin action associated with an increased risk of non-insulin-dependent diabetes mellitus
    • Dunaif, A (1995) Hyperandrogenic anovulation (PCOS): a unique disorder of insulin action associated with an increased risk of non-insulin-dependent diabetes mellitus. Am J Med 98: 33S-9S.
    • (1995) Am J Med , vol.98
    • Dunaif, A.1
  • 9
    • 0344286476 scopus 로고    scopus 로고
    • Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome
    • DOI 10.2337/diacare.22.1.141
    • Ehrmann, DA, Barnes, RB, Rosenfield, RL, Cavaghan, MK, Imperial, J (1999) Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. Diabetes Care 22: 141-146 (Pubitemid 29028311)
    • (1999) Diabetes Care , vol.22 , Issue.1 , pp. 141-146
    • Ehrmann, D.A.1    Cavaghan, M.K.2    Barnes, R.B.3    Imperial, J.4    Rosenfield, R.L.5
  • 10
    • 0141669204 scopus 로고    scopus 로고
    • Low insulin sensitivity (S(i) = 0) in diabetic and nondiabetic subjects in the insulin resistance atherosclerosis study: Is it associated with components of the metabolic syndrome and nontraditional risk factors?
    • Haffner, SM, D'Agostino, R, Jr, Festa, A, et al. (2003) Low insulin sensitivity (S(i) = 0) in diabetic and nondiabetic subjects in the insulin resistance atherosclerosis study: is it associated with components of the metabolic syndrome and nontraditional risk factors? Diabetes Care 26: 2796-2803
    • (2003) Diabetes Care , vol.26 , pp. 2796-2803
    • Haffner, S.M.1    D'Agostino Jr., R.2    Festa, A.3
  • 11
    • 0036230490 scopus 로고    scopus 로고
    • Increased proinsulin levels and decreased acute insulin response independently predict the incidence of type 2 diabetes in the insulin resistance atherosclerosis study
    • Hanley, AJ, D'Agostino, R, Jr, Wagenknecht, LE, et al. (2002) Increased proinsulin levels and decreased acute insulin response independently predict the incidence of type 2 diabetes in the insulin resistance atherosclerosis study. Diabetes 51: 1263-1270
    • (2002) Diabetes , vol.51 , pp. 1263-1270
    • Hanley, A.J.1    D'Agostino Jr., R.2    Wagenknecht, L.E.3
  • 12
    • 27444443876 scopus 로고    scopus 로고
    • Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
    • Grundy, SM, Cleeman, JI, Daniels, SR, et al. (2005) Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 112: 2735-2752
    • (2005) Circulation , vol.112 , pp. 2735-2752
    • Grundy, S.M.1    Cleeman, J.I.2    Daniels, S.R.3
  • 15
    • 0032533899 scopus 로고    scopus 로고
    • Syndrome X and mortality: A population-based study
    • A Risk Factor and Life Expectancy Research Group.
    • Trevisan, M, Liu, J, Bahsas, FB, Menotti, A Risk Factor and Life Expectancy Research Group. (1998) Syndrome X and mortality: a population-based study. Am J Epidemiol 148: 958-966
    • (1998) Am J Epidemiol , vol.148 , pp. 958-966
    • Trevisan, M.1    Liu, J.2    Bahsas, F.B.3    Menotti4
  • 16
    • 0042628161 scopus 로고    scopus 로고
    • Incidence and treatment of metabolic syndrome in newly referred women with confirmed polycystic ovarian syndrome
    • DOI 10.1016/S0026-0495(03)00104-5
    • Glueck, CJ, Papanna, R, Wang, P, Goldenberg, N, Sieve-Smith, L (2003) Incidence and treatment of metabolic syndrome in newly referred women with confirmed polycystic ovarian syndrome. Metabolism 52: 908-915 (Pubitemid 36957780)
    • (2003) Metabolism: Clinical and Experimental , vol.52 , Issue.7 , pp. 908-915
    • Glueck, C.J.1    Papanna, R.2    Wang, P.3    Goldenberg, N.4    Sieve-Smith, L.5
  • 19
    • 0037116641 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome among US adults: Findings from the Third National Health and Nutrition Examination Survey
    • Ford, ES, Giles, WH, Dietz, WH (2002) Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 287: 356-359 (Pubitemid 34251969)
    • (2002) Journal of the American Medical Association , vol.287 , Issue.3 , pp. 356-359
    • Ford, E.S.1    Giles, W.H.2    Dietz, W.H.3
  • 20
    • 0142247208 scopus 로고    scopus 로고
    • Metformin in polycystic ovary syndrome: Systematic review and meta-analysis
    • Lord, JM, Flight, IH, Norman, RJ (2003) Metformin in polycystic ovary syndrome: systematic review and meta-analysis. BMJ 327: 951-953
    • (2003) BMJ , vol.327 , pp. 951-953
    • Lord, J.M.1    Flight, I.H.2    Norman, R.J.3
  • 21
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Diabetes Prevention Program Research Group
    • Diabetes Prevention Program Research Group. (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346: 393-403.
    • (2002) N Engl J Med , vol.346 , pp. 393-403
  • 22
    • 17144389303 scopus 로고    scopus 로고
    • The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: The diabetes prevention program randomized trial
    • Orchard, TJ, Temprosa, M, Goldberg, R, et al. (2005) The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial. Ann Intern Med 142: 611-619 (Pubitemid 40529957)
    • (2005) Annals of Internal Medicine , vol.142 , Issue.8 , pp. 611-619
    • Orchard, T.J.1    Temprosa, M.2    Goldberg, R.3    Haffner, S.4    Ratner, R.5    Marcovina, S.6    Fowler, S.7
  • 23
    • 33746340623 scopus 로고    scopus 로고
    • Metformin improves endothelial vascular reactivity in first-degree relatives of type 2 diabetic patients with metabolic syndrome and normal glucose tolerance
    • DOI 10.2337/diacare.2951083
    • de Aguiar, LG, Bahia, LR, Villela, N, et al. (2006) Metformin improves endothelial vascular reactivity in first-degree relatives of type 2 diabetic patients with metabolic syndrome and normal glucose tolerance. Diabetes Care 29: 1083-1089 (Pubitemid 44115248)
    • (2006) Diabetes Care , vol.29 , Issue.5 , pp. 1083-1089
    • Kraemer De Aguiar, L.G.1    Bahia, L.R.2    Villela, N.3    Laflor, C.4    Sicuro, F.5    Wiernsperger, N.6    Bottino, D.7    Bouskela, E.8
  • 25
    • 9644295920 scopus 로고    scopus 로고
    • Metformin-diet benefits in women with polycystic ovary syndrome in the bottom and top quintiles for insulin resistance
    • DOI 10.1016/j.metabol.2004.08.007, PII S0026049504003257
    • Goldenberg, N, Glueck, CJ, Loftspring, M, Sherman, A, Wang, P (2005) Metformin-diet benefits in women with polycystic ovary syndrome in the bottom and top quintiles for insulin resistance. Metabolism 54: 113-121 (Pubitemid 39572466)
    • (2005) Metabolism: Clinical and Experimental , vol.54 , Issue.1 , pp. 113-121
    • Goldenberg, N.1    Glueck, C.J.2    Loftspring, M.3    Sherman, A.4    Wang, P.5
  • 26
    • 33745512819 scopus 로고    scopus 로고
    • The effect of metformin on fat distribution and the metabolic syndrome in women with polycystic ovary syndrome - A randomised, double-blind, placebo-controlled trial
    • DOI 10.1111/j.1471-0528.2006.00966.x
    • Lord, J, Thomas, R, Fox, B, Acharya, U, Wilkin, T (2006) The effect of metformin on fat distribution and the metabolic syndrome in women with polycystic ovary syndrome - a randomised, double-blind, placebo-controlled trial. BJOG 113: 817-824 (Pubitemid 43961744)
    • (2006) BJOG: An International Journal of Obstetrics and Gynaecology , vol.113 , Issue.7 , pp. 817-824
    • Lord, J.1    Thomas, R.2    Fox, B.3    Acharya, U.4    Wilkin, T.5
  • 27
    • 33847640229 scopus 로고    scopus 로고
    • Effects of medical therapy on insulin resistance and the cardiovascular system in polycystic ovary syndrome
    • DOI 10.2337/dc06-0618
    • Meyer, C, McGrath, BP, Teede, HJ (2007) Effects of medical therapy on insulin resistance and the cardiovascular system in polycystic ovary syndrome. Diabetes Care 30: 471-478 (Pubitemid 46354320)
    • (2007) Diabetes Care , vol.30 , Issue.3 , pp. 471-478
    • Meyer, C.1    McGrath, B.P.2    Teede, H.J.3
  • 30
    • 29144477303 scopus 로고    scopus 로고
    • Combined lifestyle modification and metformin in obese patients with polycystic ovary syndrome. a randomized, placebo-controlled, double-blind multicentre study
    • Tang, T, Glanville, J, Hayden, CJ, White, D, Barth, JH, Baien, AH (2006) Combined lifestyle modification and metformin in obese patients with polycystic ovary syndrome. A randomized, placebo-controlled, double-blind multicentre study. Hum Reprod 21: 80-89.
    • (2006) Hum Reprod , vol.21 , pp. 80-89
    • Tang, T.1    Glanville, J.2    Hayden, C.J.3    White, D.4    Barth, J.H.5    Baien, A.H.6
  • 31
    • 34249716122 scopus 로고    scopus 로고
    • Sustainability of 8% weight loss, reduction of insulin resistance, and amelioration of atherogenic-metabolic risk factors over 4 years by metformin-diet in women with polycystic ovary syndrome
    • DOI 10.1016/j.metabol.2006.08.001, PII S0026049506002678
    • Glueck, CJ, Aregawi, D, Agloria, M, Winiarska, M, Sieve, L, Wang, P (2006) Sustainability of 8% weight loss, reduction of insulin resistance, and amelioration of atherogenic-metabolic risk factors over 4 years by metformin-diet in women with polycystic ovary syndrome. Metabolism 55: 1582-1589 (Pubitemid 44827123)
    • (2006) Metabolism: Clinical and Experimental , vol.55 , Issue.12 , pp. 1582-1589
    • Glueck, C.J.1    Aregawi, D.2    Agloria, M.3    Winiarska, M.4    Sieve, L.5    Wang, P.6
  • 33
    • 0242300698 scopus 로고    scopus 로고
    • Follow-up Report on the Diagnosis of Diabetes Mellitus
    • DOI 10.2337/diacare.26.11.3160
    • Genuth, S, Alberti, KG, Bennett, P, et al. (2003) Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care 26: 3160-3167 (Pubitemid 37339514)
    • (2003) Diabetes Care , vol.26 , Issue.11 , pp. 3160-3167
    • Kahn, R.1
  • 34
    • 0037469255 scopus 로고    scopus 로고
    • C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: An 8-year follow-up of 14 719 initially healthy American women
    • Ridker, PM, Buring, JE, Cook, NR, Rifai, N (2003) C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14 719 initially healthy American women. Circulation 107: 391-397
    • (2003) Circulation , vol.107 , pp. 391-397
    • Ridker, P.M.1    Buring, J.E.2    Cook, N.R.3    Rifai, N.4
  • 35
    • 0347716449 scopus 로고    scopus 로고
    • Association of the Metabolic Syndrome with History of Myocardial Infarction and Stroke in the Third National Health and Nutrition Examination Survey
    • DOI 10.1161/01.CIR.0000108926.04022.0C
    • Ninomiya, JK, L'Italien, G, Criqui, MH, Whyte, JL, Gamst, A, Chen, RS (2004) Association of the metabolic syndrome with history of myocardial infarction and stroke in the Third National Health and Nutrition Examination Survey. Circulation 109: 42-46. (Pubitemid 38056019)
    • (2004) Circulation , vol.109 , Issue.1 , pp. 42-46
    • Ninomiya, J.K.1    L'Italien, G.2    Criqui, M.H.3    Whyte, J.L.4    Gamst, A.5    Chen, R.S.6
  • 36
    • 18744381558 scopus 로고    scopus 로고
    • American Association of Clinical Endocrinologists Position Statement on Metabolic and Cardiovascular Consequences of Polycystic Ovary Syndrome
    • Cobin, RH, Futterweit, W, Nestler, JE, et al. (2005) American Association of Clinical Endocrinologists Position Statement on Metabolic and Cardiovascular Consequences of Polycystic Ovary Syndrome. Endocr Pract 11: 125-134
    • (2005) Endocr Pract , vol.11 , pp. 125-134
    • Cobin, R.H.1    Futterweit, W.2    Nestler, J.E.3
  • 37
    • 34249912568 scopus 로고    scopus 로고
    • Metformin improves menstrual patterns, endocrine and metabolic profile in obese hyperinsulinemic women with a polycystic ovary syndrome
    • Krstevska, B, Dimitrovski, C, Pemovska, G, et al. (2006) Metformin improves menstrual patterns, endocrine and metabolic profile in obese hyperinsulinemic women with a polycystic ovary syndrome. Prilozi 27: 57-66.
    • (2006) Prilozi , vol.27 , pp. 57-66
    • Krstevska, B.1    Dimitrovski, C.2    Pemovska, G.3
  • 38
    • 0034458234 scopus 로고    scopus 로고
    • Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: A randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation
    • DOI 10.1210/jc.85.1.139
    • Moghetti, P, Castello, R, Negri, C, et al. (2000) Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: a randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation. J Clin Endocrinol Metab 85: 139-146 (Pubitemid 32268804)
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , Issue.1 , pp. 139-146
    • Moghetti, P.1    Castello, R.2    Negri, C.3    Tosi, F.4    Perrone, F.5    Caputo, M.6    Zanolin, E.7    Muggeo, M.8
  • 39
    • 0036675187 scopus 로고    scopus 로고
    • The role of lifestyle modification in polycystic ovary syndrome
    • DOI 10.1016/S1043-2760(02)00612-4, PII S1043276002006124
    • Norman, RJ, Davies, MJ, Lord, J, Moran, LJ (2002) The role of lifestyle modification in polycystic ovary syndrome. Trends Endocrinol Metab 13: 251-257 (Pubitemid 36733970)
    • (2002) Trends in Endocrinology and Metabolism , vol.13 , Issue.6 , pp. 251-257
    • Norman, R.J.1    Davies, M.J.2    Lord, J.3    Moran, L.J.4
  • 40
    • 0031015005 scopus 로고    scopus 로고
    • Effects of metformin on insulin secretion, insulin action, and ovarian steroidogenesis in women with polycystic ovary syndrome
    • Ehrmann, DA, Cavaghan, MK, Imperial, J, Sturis, J, Rosenfield, RL, Polonsky, KS (1997) Effects of metformin on insulin secretion, insulin action, and ovarian steroidogenesis in women with polycystic ovary syndrome. J Clin Endocrinol Metab 82: 524-530
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 524-530
    • Ehrmann, D.A.1    Cavaghan, M.K.2    Imperial, J.3    Sturis, J.4    Rosenfield, R.L.5    Polonsky, K.S.6
  • 41
    • 36249013118 scopus 로고    scopus 로고
    • The effects of metformin on metabolic and cardiovascular risk factors in nonobese women with polycystic ovary syndrome
    • DOI 10.1111/j.1365-2265.2007.02985.x
    • Sahin, Y, Unluhizarci, K, Yilmazsoy, A, Yikilmaz, A, Aygen, E, Kelestimur, F (2007) The effects of metformin on metabolic and cardiovascular risk factors in non-obese women with polycystic ovary syndrome. Clin Endocrinol (Oxf) 67: 904-908 (Pubitemid 350135135)
    • (2007) Clinical Endocrinology , vol.67 , Issue.6 , pp. 904-908
    • Sahin, Y.1    Unluhizarci, K.2    Yilmazsoy, A.3    Yikilmaz, A.4    Aygen, E.5    Kelestimur, F.6
  • 42
    • 42949103243 scopus 로고    scopus 로고
    • Efficacy of metformin in obese and non-obese women with polycystic ovary syndrome: A randomized, double-blinded, placebo-controlled cross-over trial
    • DOI 10.1093/humrep/dem271
    • Trolle, B, Flyvbjerg, A, Kesmodel, U, Lauszus, FF (2007) Efficacy of metformin in obese and non-obese women with polycystic ovary syndrome: a randomized, double-blinded, placebo-controlled cross-over trial. Hum Reprod 22: 2967-2973 (Pubitemid 351696807)
    • (2007) Human Reproduction , vol.22 , Issue.11 , pp. 2967-2973
    • Trolle, B.1    Flyvbjerg, A.2    Kesmodel, U.3    Lauszus, F.F.4
  • 44
    • 21244465167 scopus 로고    scopus 로고
    • Changes in glucose tolerance over time in women with polycystic ovary syndrome: A controlled study
    • DOI 10.1210/jc.2004-1843
    • Legro RS, Gnatuk CL, Kunselman AR, Dunaif A. Changes in glucose tolerance over time in women with polycystic ovary syndrome: a controlled study. J Clin Endocrinol Metab 2005; 90: 3236-3242 (Pubitemid 41014281)
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , Issue.6 , pp. 3236-3242
    • Legro, R.S.1    Gnatuk, C.L.2    Kunselman, A.R.3    Dunaif, A.4
  • 45
    • 0034815278 scopus 로고    scopus 로고
    • Relative risk of conversion from normoglycaemia to impaired glucose tolerance or non-insulin dependent diabetes mellitus in polycystic ovarian syndrome
    • Norman, RJ, Masters, L, Milner, CR, Wang, JX, Davies, MJ (2001) Relative risk of conversion from normoglycaemia to impaired glucose tolerance or non-insulin dependent diabetes mellitus in polycystic ovarian syndrome. Hum Reprod 16: 1995-1998 (Pubitemid 32916235)
    • (2001) Human Reproduction , vol.16 , Issue.9 , pp. 1995-1998
    • Norman, R.J.1    Masters, L.2    Milner, C.R.3    Wang, J.X.4    Davies, M.J.5
  • 46
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Diabetes Prevention Program Research Group
    • Diabetes Prevention Program Research Group. (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 346: 393-403.
    • (2002) N Engl J Med , vol.346 , pp. 393-403
  • 47
    • 0042266224 scopus 로고    scopus 로고
    • Prevalence and characteristics of the metabolic syndrome in the San Antonio Heart and Framingham Offspring Studies
    • DOI 10.2337/diabetes.52.8.2160
    • Meigs, JB, Wilson, PW, Nathan, DM, D'Agostino, RB, Sr., Williams, K, Haffner, SM (2003) Prevalence and characteristics of the metabolic syndrome in the San Antonio Heart and Framingham Offspring Studies. Diabetes 52: 2160-2167 (Pubitemid 36919812)
    • (2003) Diabetes , vol.52 , Issue.8 , pp. 2160-2167
    • Meigs, J.B.1    Wilson, P.W.F.2    Nathan, D.M.3    D'Agostino Sr., R.B.4    Williams, K.5    Haffner, S.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.