The apicobasal polarity kinase aPKC functions as a nuclear determinant and regulates cell proliferation and fate during Xenopus primary neurogenesis

Development

Volumn 136, Issue 16, 2009, Pages 2767-2777

  Sabherwal, Nitin ^a   Tsutsui, Akiko ^a   Hodge, Sarah ^a,c   Wei, Jun ^b   Chalmers, Andrew D ^b   Papalopulu, Nancy ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b University of Bath   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

aPKC; Lgl; Polarity; Primary neurons; Xenopus

Indexed keywords

GENE PRODUCT; LETHAL GIANT LARVAE PROTEIN 2; NEUROGENIN 1; PROTEIN KINASE C; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL FATE; CELL MEMBRANE DEPOLARIZATION; CELL NUCLEUS; CELL POLARITY; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; GENE LOCATION; GENE OVEREXPRESSION; HELA CELL; HUMAN; HUMAN CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; XENOPUS;

AMINO ACID MOTIFS; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BETA KARYOPHERINS; BIOLOGICAL MARKERS; CELL NUCLEUS; CELL POLARITY; CELL PROLIFERATION; HELA CELLS; HUMANS; IN SITU HYBRIDIZATION; NERVE TISSUE PROTEINS; NEUROGENESIS; NUCLEAR LOCALIZATION SIGNALS; PROTEIN KINASE C; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; TUBULIN; XENOPUS LAEVIS; XENOPUS PROTEINS;

EID: 68349099743     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.034454     Document Type: Article

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