Establishment and biological analysis of the EC109/CDDP multidrug-resistant esophageal squamous cell carcinoma cell line

Oncology Reports

Volumn 22, Issue 1, 2009, Pages 65-71

  Wen, Jing ^a   Zheng, Bin ^a   Hu, Yi ^a   Zhang, Xu ^a   Yang, Hong ^a   Luo, Kong Jia ^a   Zhang, Xing ^a   Li, Yong Feng ^a   Fu, Jian Hua ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

Author keywords

Cell line; Esophageal squamous cell carcinoma; Multidrug resistance

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; ETOPOSIDE; FLUOROURACIL; GLUTATHIONE TRANSFERASE P1; IRINOTECAN; LUNG RESISTANCE PROTEIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; NAVELBINE; PACLITAXEL; PIRARUBICIN;

ARTICLE; CANCER CELL CULTURE; CANCER CELL LINE EC109 CDDP; CANCER GROWTH; CANCER MORPHOLOGY; CELL CYCLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FLOW CYTOMETRY; GENE EXPRESSION; GROWTH CURVE; HUMAN; HUMAN CELL; MICROSCOPY; MULTIDRUG RESISTANCE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; CARCINOMA, SQUAMOUS CELL; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; ESOPHAGEAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTATHIONE S-TRANSFERASE PI; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; P-GLYCOPROTEIN; PHENOTYPE; RNA, MESSENGER; VAULT RIBONUCLEOPROTEIN PARTICLES;

EID: 68249143419     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000407     Document Type: Article

References (23)

1. Parkin DM, Bray FI and Devesa SS: Cancer burden in the year 200. The global picture. Eur J Cancer 37: S4-S66, 2001.
2. Siewert JR and Ott K: Are squamous and adenocarcinomas of the esophagus the same disease? Semin Radiat Oncol 17: 38-44, 2007.
3. Stein HJ, Sendler A, Fink U and Siewert JR: Multidisciplinary approach to esophageal and gastric cancer. Surg Clin North Am 80: 659-682, 2000.
4. Juliano RL and Ling V: A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Biophys Acta 455: 152-162, 1976.
5. Yan XD, Li M, Yuan Y, Mao N and Pan LY: Biological comparison of ovarian cancer resistant cell lines to cisplatin and taxol by two different administrations. Oncol Rep 17: 1163-1169, 2007.
6. Cole SP, Bhardwaj G, Gerlach JH, et al: Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 258: 1650-1654, 1992.
7. Scheper RJ, Broxterman HJ, Scheffer GL, et al: Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance. Cancer Res 53: 1475-1479, 1993.
8. Doyle LA, Yang W, Abruzzo LV, Krogmann T, Gao Y, Rishi AK and Ross DD: A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci USA 95: 15665-15670, 1998.
9. Gutmann H, Fricker G, Torok M, Michael S, Beglinger C and Drewe J: Evidence for different ABC-transporters in Caco-2 cells modulating drug uptake. Pharm Res 16: 402-407, 1999.
10. Grant CE, Kurz EU, Cole SP and Deeley RG: Analysis of the intron-exon organization of the human multidrug-resistance protein gene (MRP) and alternative splicing of its mRNA. Genomics 45: 368-378, 1997.
11. Deichmann M, Thome M, Egner U, Hartschuh W and Kurzen H: The chemoresistance gene ABCG2 (MXR/BCRP1/ABCP1) is not expressed in melanomas but in single neuroendocrine carcinomas of the skin. J Cutan Pathol 32: 467-473, 2005.
12. Baron JM, Holler D, Schiffer R, Frankenberg S, Neis M, Merk HF and Jugert FK: Expression of multiple cytochrome p450 enzymes and multidrug resistance-associated transport proteins in human skin keratinocytes. J Invest Dermatol 116: 541-548, 2001.
13. Kuzma M, Jamrozik Z and Baranczyk-Kuzma A: Activity and expression of glutathione S-transferase pi in patients with amyotrophic lateral sclerosis. Clin Chim Acta 364: 217-221, 2006.
14. Siddik ZH: Cisplatin: Mode of cytotoxic action and molecular basis of resistance. Oncogene 22: 7265-7279, 2003.
15. Toshimitsu H, Hashimoto K, Tangoku A, et al: Molecular signature linked to acquired resistance to cisplatin in esophageal cancer cells. Cancer Lett 211: 69-78, 2004.
16. Cui HJ, Jin G, Yang HY, Huang YT, Zheng ZM, Zhao JM and Dong ZM: Expression of DNA polymerase β in a cisplatin-induced human esophageal cancer drug-resistant cell line. J Zhengzhou University (Medical Sciences) 40: 17-19, 2005.
17. Li M, Wang ZJ, Fu Q, Zhao GQ and Dong ZM: Establishment of a cisplatin-induced human esophageal carcinoma a drug resistant cell line and screening of drug resistance-related genes. Chin J Health Lab Tech 17: 18-20, 2007.
18. Meijera C, van Luyn MJ, Nienhuis EF, Blom N, Mulder NH and de Vries EG: Ultrastructural morphology and localisation of cisplatin-induced platinum-DNA adducts in a cisplatin-sensitive and -resistant human small cell lung cancer cell line using electron microscopy. Biochem Pharmacol 61: 573-578, 2001.
19. Longley DB and Johnston PG: Molecular mechanisms of drug resistance. J Pathol 205: 275-292, 2005.
20. Ranganathan AC, Adam AP, Zhang L and Aguirre-Ghiso JA: Tumor cell dormancy induced by p38SAPK and ER-stress signaling: An adaptive advantage for metastatic cells? Cancer Biol Ther 5: 729-735, 2006.
21. Gottesman MM, Fojo T and Bates SE: Multidrug resistance in cancer: Role of ATP-dependent transporters. Nat Rev 2: 48-58, 2002.
22. Li L, Luan Y, Wang G, et al: Development and characterization of five cell models for chemoresistance studies of human ovarian carcinoma. Int J Mol Med 14: 257-264, 2004.
23. Gomez-Martinez A, Garcia-Morales P, Carrato A, et al: Post-transcriptional regulation of P-glycoprotein expression in cancer cell lines. Mol Cancer Res 5: 641-653, 2007.