Prenatal cigarette smoke decreases lung cAMP and increases airway hyperresponsiveness

American Journal of Respiratory and Critical Care Medicine

Volumn 168, Issue 3, 2003, Pages 342-347

  Singh, Shashi P ^b   Barrett, Edward G ^b   Kalra, Roma ^b   Razani Boroujerdi, Seddigheh ^b   Langley, Raymond J ^b   Kurup, Viswanath ^b   Tesfaigzi, Yohannes ^b   Sopori, Mohan L ^a  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^b NONE

Author keywords

Airway responsiveness; Aspergiltus fumigatus; Asthma; Phosphodiesterase 4D

Indexed keywords

CIGARETTE SMOKE; CYCLIC AMP; ISOENZYME; MESSENGER RNA; PHOSPHODIESTERASE IV;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPERGILLUS FUMIGATUS; BRONCHUS HYPERREACTIVITY; CIGARETTE SMOKING; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; LEUKOCYTE MIGRATION; LUNG FUNCTION; MALE; MOUSE; NONHUMAN; PERINATAL PERIOD; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY TRACT MUCOSA; TISSUE LEVEL;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; BRONCHIAL HYPERREACTIVITY; CYCLIC AMP; DISEASE MODELS, ANIMAL; FEMALE; LUNG; MALE; MICE; MICE, INBRED BALB C; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; TOBACCO SMOKE POLLUTION;

EID: 0043124468     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.200211-1262OC     Document Type: Article

References (53)

1. Sopori M. Effects of cigarette smoke on the immune system. Nat Rev Immunol 2002;2:372-377.
2. Frischer T, Kuer J, Meinert R, Karmaus W, Barth R, Hermann-Kunz E, Urbanek R. Maternal smoking in early childhood: a risk factor for bronchial responsiveness to exercise in primary-school children. J Pediatr 1992;121:17-22.
3. Martinez FD, Cline M, Burrows B. Increased incidence of asthma in children of smoking mothers. Pediatrics 1992;89:157-167.
4. Cunningham J, Dockery DW, Speizer FE. Maternal smoking during pregnancy as a predictor of lung function in children. Am J Epidemiol 1994;139:1139-1152.
5. Cunningham J, O'Conner GT, Dockery DW, Speizer FE. Environmental tobacco smoke, wheezing, and asthma in children in 24 communities. Am J Respir Crit Care Med 1996;153:218-224.
6. Ehrlich RI, Du Toit D, Jordaan E, Zwarenstein M, Potter P, Volmink JA, Weinberg E. Risk factors for childhood asthma and wheezing: importance of maternal and household smoking. Am J Respir Crit Care Med 1996;154:681-688.
7. Osur SL. Viral respiratory infections in association with asthma and sinusitis: a review. Ann Allergy Asthma Immunol 2002;89:553-560.
8. Lemanske RF Jr. Viruses and asthma: inception, exacerbation, and possible prevention. J Pediatr 2003;142:3S-8S.
9. Chulada PC, Arbes SJ Jr, Dunson D, Zeldin DC. Breast-feeding and the prevalence of asthma and wheeze in children: analyses from the third national health and nutrition examination survey, 1988-1994. J Allergy Clin Immunol 2003;111:328-336.
10. Peroni DG, Chatzimichail A, Boner AL. Food allergy: what can be done to prevent progression to asthma? Ann Allergy Asthma Immunol 2002;89:44-51.
11. Boulay ME, Boulet LP. The relationships between atopy, rhinitis and asthma: pathophysiological considerations. Curr Opin Allergy Clin Immunol 2003;3:51-55.
12. Landau LI. Parental smoking: asthma and wheezing illnesses in infants and children. Paediatr Respir Rev 2001;2:202-206.
13. Liu AH. Endotoxin exposure in allergy and asthma: reconciling a paradox. J Allergy Clin Immunol 2002;109:379-392.
14. Tager IB, Ngo L, Hanrahan JP. Maternal smoking during pregnancy: effects on lung function during the first 18 months of life. Am J Respir Crit Care Med 1995;152:977-983.
15. Hoo A-F, Henschen M, Dezateux C, Costeloe K, Stocks J. Respiratory function among preterm infants whose mothers smoked during pregnancy. Am J Respir Crit Care Med 1998;158:700-705.
16. Floreani AA, Rennard SI. The role of cigarette smoke in the pathogenesis of asthma and as a trigger for acute symptoms. Curr Opin Pulm Med 1999;5:38-46.
17. Sopori ML, Goud NS, Kaplan AM. Effects of tobacco smoke on the immune system. In: Dean JH, Luster MI, Munson AE, Kimber I, editors. Immunotoxicology and immunopharmacology. New York: Raven Press; 1994. p. 413-434.
18. Holt PG, Keast D. Environmentally induced changes in immunological function: acute and chronic effects of inhalation of tobacco smoke and other atmospheric contaminants in man and experimental animals. Bacteriol Rev 1997;41:205-214.
19. Tenor H, Schudt C. Phosphodiesterases in asthma. In: Sampson AP, Church MK, editors. Anti-inflammatory drugs in asthma. Basel, Switzerland: Birkhauser; 1999. p. 87-135.
20. Fleming CM, He H, Ciota A, Perkins D, Finn PW. Administration of pentoxifylline during allergen sensitization dissociates pulmonary allergic inflammation from airway hyperresponsiveness. J Immunol 2001;167:1703-1711.
21. Tomlinson PR, Wilson JW, Stewart AG. Salbutamol inhibits the proliferation of human airway smooth muscle cells grown in culture: relationship to elevated cAMP level. Biochem Pharmacol 1995;49:1809-1819.
22. Beavo JA. Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. Physiol Rev 1995;75:725-748.
23. Chan SC, Reifsnyder D, Beavo JA, Hanifin JM. Immunochemical characterization of the distinct monocyte cyclic AMP-phosphodiesterase from patients with atopic dermatitis. J Allergy Clin Immunol 1993;91:1179-1188.
24. Bolger G, McPhee I, Houslay MD. Alternative splicing of cAMP-specific phosphodiesterase mRNA transcripts: characterization of a novel tissue-specific isoform, RNPDE4A8. J Biol Chem 1996;271:1065-1071.
25. Hansen G, Catherine Jin S-L, Umetsu DT, Conti M. Absence of muscarinic cholinergic airway responses in mice deficient in the cyclic nucleotide phosphodiesterase PDE4D. Proc Natl Acad Sci USA 2000;97:6751-6756.
26. Barrett EG, Wilder JA, March TH, Espindola T, Bice DE. Cigarette smoke-induced airway hyperresponsiveness is not dependent on elevated immunoglobulin and eosinophilic inflammation in a mouse model of allergic airway disease. Am J Respir Crit Care Med 2002;165:1410-1418.
27. Finch GL, Nikula KJ, Chen BT, Barr EB, Chang IY, Hobbs CH. Effect of chronic cigarette smoke exposure on lung clearance of tracer particles inhaled by rats. Fundam Appl Toxicol 1995;24:76-85.
28. Kurup VP, Mauze S, Choi H, Seymour BW, Coffman RL. A murine model of allergic bronchopulmonary aspergillosis with elevated eosinophils and IgE. J Immunol 1992;148:3783-3788.
29. Bardana EJ Jr. The clinical spectrum of aspergillosis: I: epidemiology, pathogenicity, infection in animals and immunology of Aspergillus. Crit Rev Clin Lab Sci 1981;13:21-83.
30. Kurup VP, Choi HY, Murali PS, Xia JQ, Coffman RL, Fink JN. Immune responses to Aspergillus antigen in IL-4-/- mice and the effect of eosinophil ablation. Allergy 1999;54:420-427.
31. Lennart K, Lundblad A, Irvine CG, Adler A, Bates JHT. A reevaluation of the validity of unrestrained plethysmography in mice. J Appl Physiol 2002;93:1198-1207.
32. Chong BT, Agrawal DK, Romero FA, Townley RG. Measurement of bronchoconstriction using whole-body plethysmograph: comparison of freely moving versus restrained guinea pigs. J Pharmacol Toxicol Meth 1998;39:163-168.
33. Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, Irvin CG, Gelfand E. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med 1997;156:766-775.
34. DeLorme MP, Moss OR. Pulmonary function assessment by whole-body plethysmography in restrained versus unrestrained mice. J Pharmacol Toxicol Methods 2002;47:1-10.
35. Jin S-L, Bushnik T, Lan L, Conti M. Subcellular localization of rolipramsensitive, cAMP-specific phosphodiesterases: differential targeting and activation of the splicing variants derived from the PDE4D gene. J Biol Chem 1998;273:19672-19678.
36. Thompson WJ, Brooker G, Appleman MM. Assay of cyclic nucleotide phosphodiesterases with radioactive substrates. Methods Enzymol 1974;38:205-212.
37. Jedrychowski W, Flak E. Confronting the prenatal effects of active and passive tobacco smoking on the birth weight of children. Cent Eur J Public Health 1996;4:201-205.
38. Lecomte J. Asthma and exercise [review]. Rev Med Brux 2002;23:A206-A210.
39. Debrock C, Monetrey C, Bonarvent, M, Antonine MT, Preux PM, Bonnand F, Vergnenegre A. Prevalence of exercise-induced asthma in school children. Rev Epidemiol Sante Publique 2002;50:519-529.
40. Wong WS, Koh DS. Advances in immunopharmacology of asthma. Biochem Pharmacol 20;59:1323-1335.
41. Dutta EJ, Li JT. Beta-agonists. Med Clin North Am 2002;86:991-1008.
42. Lipworth BJ, Jackson CM. Marginal benefits of adding formoterol. Thorax 2002;57:1089.
43. Trifilieff A, Wyss D, Walker C, Mazzoni L, Hersperger R. Pharmacological profile of a novel phosphodiesterase 4 inhibitor, 4-(8-benzo[1,2,5]-oxadiazol-5-yl-[1,7]naphthyridin-6-yl)-benzoic acid (NVP-ABE171), a 1,7-naphthyridine derivative, with anti-inflammatory activities. J Pharmacol Exp Ther 2002;301:241-248.
44. Dyke HJ, Montana JG. Update on the therapeutic potential of PDE4 inhibitors. Expert Opin Investig Drugs 2002;11:1-13.
45. Billah MM, Cooper N, Minnicozzi M, Warneck J, Wang P, Hey JA, Kreutner W, Rizzo CA, Smith SR, Young S, et al. Pharmacology of N-(3,5-dichloro-1-oxido-4-pyridinyl)-8-methoxy-2-(trifluromethyl)-5-quinoline carboxamide (SCH 351591), a novel, orally active phosphodiesterase-4 inhibitor. J Pharmacol Exp Ther 2002;302:127-137.
46. Anderson SE, De Monaco D, Buechler U, Triller J, Gerich U, Dalinka M, Stauffer E, Nagy L, Neidecker A, Campbell R, et al. Imaging features of pseudoaneurysms of the hand in children and adults. Am J Roentgenol 2003;180:659-664.
47. Green R, Custoric MA, Sanderson G, Hunter J, Johnston SL, Woodcock A. Synergism between allergens and viruses and risk of hospital admission with asthma: case-control study. BMJ 2002;324:763. [Published erratum appears in BMJ 324:1131.]
48. Message SD, Johnston SL. Viruses in asthma. Br Med Bull 2002;61:29-43.
49. Lodrup KC, Carlsen KH. Effects of maternal and early tobacco exposure on the development of asthma and airway hyperreactivity. Curr Opin Allergy Clin Immunol 2001;1:139-143.
50. Ball TM, Castro-Rodriguez, JA, Griffith KA, Holberg CJ, Martinez FD, Wright AL. Siblings, day-care attendance, and the risk of asthma and wheezing during childhood. N Engl J Med 2000;343:538-543.
51. Cortijo J, Bou J, Beleta J, Cardelus I, Lienas J, Morcillo E, Gristwood RW. Investigation into the role of phosphodiesterase IV in bronchorelaxation, including studies with human bronchus. Br J Pharmacol 1993;108:562-568.
52. Raeburn D, Advenier C. Isoenzyme-selective cyclic nucleotide phosphodiesterase inhibitors: effects on airways smooth muscle. Int J Biochem Cell Biol 1995;27:29-37.
53. Giembycz MA. Cilomilast: a second generation phosphodiesterase 4 inhibitor for asthma and chronic obstructive pulmonary disease. Expert Opin Investig Drugs 2001;10:1361-1391.