Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle

FEBS Journal

Volumn 276, Issue 15, 2009, Pages 4102-4118

  Kaimachnikov, Nikolai P ^a,b   Kholodenko, Boris N ^a,c  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b INSTITUTE OF CELL BIOPHYSICS   (Russian Federation)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Autophosphorylation; Bistability; Excitable behavior; Oscillations; Src family kinases

Indexed keywords

PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE;

ARTICLE; COMPUTER PROGRAM; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME REGULATION; EXCITABILITY; GENE OVEREXPRESSION; KINETICS; MATHEMATICAL MODEL; OSCILLATION; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STIMULUS RESPONSE;

ANIMALS; CELL DIFFERENTIATION; CELL MOVEMENT; DNA REPLICATION; ENZYME ACTIVATION; KINETICS; PHOSPHORYLATION; PROTEIN CONFORMATION; SRC-FAMILY KINASES; VERTEBRATES;

EID: 68149171467     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07117.x     Document Type: Article

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