Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 16, 2009, Pages 5962-5967

  Monforte, Anna Maria ^a   Logoteta, Patrizia ^a   Ferro, Stefania ^a   Luca, Laura De ^a   Iraci, Nunzio ^a   Maga, Giovanni ^b   Clercq, Erik De ^c   Pannecouque, Christophe ^c   Chimirri, Alba ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b CNR   (Italy)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Dihydrobenzimidazol 2 ones; HIV; RT; Synthesis

Indexed keywords

1,3 DIHYDROBENZIMIDAZOL 2 ONE DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANTI-HIV AGENTS; BENZIMIDAZOLES; CELL LINE; DRUG DESIGN; HIV REVERSE TRANSCRIPTASE; HUMANS; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 68149144263     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.06.068     Document Type: Article

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