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Volumn 23, Issue 6, 2009, Pages 1195-1204

Hemolytic and genotoxic evaluation of organochalcogens in human blood cells in vitro

Author keywords

DNA damage; Erythrocytes; Osmotic fragility; Selenium; Tellurium

Indexed keywords

2 (BUTYLTELLURIUM)FURAN; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BUTYL(STYRYL)TELLURIDE; CATALASE; DIPHENYL DISELENIDE; DIPHENYL DITELLURIDE; DIPHENYL SELENIDE; DIPHENYL TELLURIDE; DITHIOTHREITOL; ORGANOSELENIUM DERIVATIVE; ORGANOTELLURIUM DERIVATIVE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

EID: 68049110327     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.05.010     Document Type: Article
Times cited : (36)

References (79)
  • 1
    • 0021318441 scopus 로고
    • Catalase "in vitro"
    • Aebi H. Catalase "in vitro". Methods in Enzymology 105 (1984) 121-127
    • (1984) Methods in Enzymology , vol.105 , pp. 121-127
    • Aebi, H.1
  • 2
    • 0028889014 scopus 로고
    • The oxidation of ebselen metabolites to thiol oxidants catalyzed by liver microsomes and perfused rat liver
    • Akerboom T.P., Sies H., and Ziegler D.M. The oxidation of ebselen metabolites to thiol oxidants catalyzed by liver microsomes and perfused rat liver. Archives of Biochemistry and Biophysics 316 (1995) 220-226
    • (1995) Archives of Biochemistry and Biophysics , vol.316 , pp. 220-226
    • Akerboom, T.P.1    Sies, H.2    Ziegler, D.M.3
  • 4
    • 0033775891 scopus 로고    scopus 로고
    • Physiological functions of thioredoxin and thioredoxin reductase
    • Arner E.S., and Holmgren P. Physiological functions of thioredoxin and thioredoxin reductase. European Journal of Biochemistry 267 (2000) 6102-6109
    • (2000) European Journal of Biochemistry , vol.267 , pp. 6102-6109
    • Arner, E.S.1    Holmgren, P.2
  • 7
    • 0018664952 scopus 로고
    • Hemoglobin-depleted human erythrocyte ghosts: characterization of morphology and transport functions
    • Bjerrum P.J. Hemoglobin-depleted human erythrocyte ghosts: characterization of morphology and transport functions. The Journal of Membrane Biology 48 (1979) 43-67
    • (1979) The Journal of Membrane Biology , vol.48 , pp. 43-67
    • Bjerrum, P.J.1
  • 8
    • 84984585749 scopus 로고    scopus 로고
    • Organochalcogens affect the glutamatergic neurotransmission in human platelets
    • Borges V.C., Nogueira C.W., Zeni G., and Rocha J.B. Organochalcogens affect the glutamatergic neurotransmission in human platelets. Neurochemical Research 29 (2004) 1505-1509
    • (2004) Neurochemical Research , vol.29 , pp. 1505-1509
    • Borges, V.C.1    Nogueira, C.W.2    Zeni, G.3    Rocha, J.B.4
  • 9
    • 84984538675 scopus 로고    scopus 로고
    • Effect of diphenyl diselenide, diphenyl ditelluride and ebselen on cerebral Na(+), K(+)-ATPase activity in rats
    • Borges V.C., Rocha J.B., and Nogueira C.W. Effect of diphenyl diselenide, diphenyl ditelluride and ebselen on cerebral Na(+), K(+)-ATPase activity in rats. Toxicology 215 (2005) 191-197
    • (2005) Toxicology , vol.215 , pp. 191-197
    • Borges, V.C.1    Rocha, J.B.2    Nogueira, C.W.3
  • 10
    • 84984569849 scopus 로고    scopus 로고
    • Repeated administration of diphenyl ditelluride induces hematological disorders in rats
    • An International Journal Published for the British Industrial Biological Research Association
    • Borges V.C., Rocha J.B., Savegnago L., and Nogueira C.W. Repeated administration of diphenyl ditelluride induces hematological disorders in rats. Food and Chemical Toxicology 45 (2007) 1453-1458 An International Journal Published for the British Industrial Biological Research Association
    • (2007) Food and Chemical Toxicology , vol.45 , pp. 1453-1458
    • Borges, V.C.1    Rocha, J.B.2    Savegnago, L.3    Nogueira, C.W.4
  • 11
    • 84984567395 scopus 로고    scopus 로고
    • 1,1,2-Tris-organoselenide alkene derivatives, but not 1,2-bis-organoselenide alkene derivatives, inhibited delta-aminolevulinate dehydratase activity from human erythrocytic cells in vitro
    • Borges V.C., Dadalt G., Savegnago L., Moro A.V., Rocha J.B., and Nogueira C.W. 1,1,2-Tris-organoselenide alkene derivatives, but not 1,2-bis-organoselenide alkene derivatives, inhibited delta-aminolevulinate dehydratase activity from human erythrocytic cells in vitro. Toxicology In Vitro 21 (2007) 387-391
    • (2007) Toxicology In Vitro , vol.21 , pp. 387-391
    • Borges, V.C.1    Dadalt, G.2    Savegnago, L.3    Moro, A.V.4    Rocha, J.B.5    Nogueira, C.W.6
  • 13
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the qualification of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the qualification of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72 (1976) 248-254
    • (1976) Analytical Biochemistry , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 14
    • 0141631574 scopus 로고    scopus 로고
    • Synthesis of new chiral aliphatic amino diselenides and their application as catalysts for the enantioselective addition of diethylzinc to aldehydes
    • Braga A.L., Paixão M.W., Ludtke D.S., Silveira C.C., and Rodrigues O.E. Synthesis of new chiral aliphatic amino diselenides and their application as catalysts for the enantioselective addition of diethylzinc to aldehydes. Organic Letters 5 (2003) 2635-2638
    • (2003) Organic Letters , vol.5 , pp. 2635-2638
    • Braga, A.L.1    Paixão, M.W.2    Ludtke, D.S.3    Silveira, C.C.4    Rodrigues, O.E.5
  • 16
    • 34248534223 scopus 로고    scopus 로고
    • Genotoxic and antigenotoxic properties of selenium compounds in the in vitro micronucleus assay with human whole blood lymphocytes and TK6 lymphoblastoid cells
    • Cemeli E., Marcos R., and Anderson D. Genotoxic and antigenotoxic properties of selenium compounds in the in vitro micronucleus assay with human whole blood lymphocytes and TK6 lymphoblastoid cells. The Scientific World Journal 6 (2006) 1202-1210
    • (2006) The Scientific World Journal , vol.6 , pp. 1202-1210
    • Cemeli, E.1    Marcos, R.2    Anderson, D.3
  • 18
    • 0029919136 scopus 로고    scopus 로고
    • Selenium poisoning from a nutritional supplement
    • Clark R.F., Strukle E., Williams S.R., and Manoguerra A.S. Selenium poisoning from a nutritional supplement. JAMA 275 (1996) 1087-1088
    • (1996) JAMA , vol.275 , pp. 1087-1088
    • Clark, R.F.1    Strukle, E.2    Williams, S.R.3    Manoguerra, A.S.4
  • 19
    • 8544283254 scopus 로고    scopus 로고
    • The comet assay for DNA damage and repair
    • Collins A.R. The comet assay for DNA damage and repair. Molecular Biotechnology 26 (2004) 249-261
    • (2004) Molecular Biotechnology , vol.26 , pp. 249-261
    • Collins, A.R.1
  • 22
    • 0026792957 scopus 로고
    • Tellurite-induced damage of the erythrocyte membrane. Manifestations and mechanisms
    • Deuticke B., Lütkemeier P., and Poser B. Tellurite-induced damage of the erythrocyte membrane. Manifestations and mechanisms. Biochimica et Biophysica Acta 10 (1992) 97-107
    • (1992) Biochimica et Biophysica Acta , vol.10 , pp. 97-107
    • Deuticke, B.1    Lütkemeier, P.2    Poser, B.3
  • 23
    • 0034971472 scopus 로고    scopus 로고
    • Lipid peroxidation, osmotic fragility and antioxidant status in children with acute post-streptococcal glomerulonephritis
    • Devasena T., Lalitha S., and Padma K. Lipid peroxidation, osmotic fragility and antioxidant status in children with acute post-streptococcal glomerulonephritis. Clinica Chimica Acta: International Journal of Clinical Chemistry 308 (2001) 155-161
    • (2001) Clinica Chimica Acta: International Journal of Clinical Chemistry , vol.308 , pp. 155-161
    • Devasena, T.1    Lalitha, S.2    Padma, K.3
  • 30
    • 0019451602 scopus 로고
    • High prevalence of increased osmotic fragility of red blood cells among Norwegian blood donors
    • Godal H.C., and Heisto H. High prevalence of increased osmotic fragility of red blood cells among Norwegian blood donors. Scandinavian Journal of Haematology 27 (1981) 30-34
    • (1981) Scandinavian Journal of Haematology , vol.27 , pp. 30-34
    • Godal, H.C.1    Heisto, H.2
  • 31
    • 0028225059 scopus 로고
    • Oxidation of dimethylselenide to dimethylselenoxide by microsomes from rat liver and lung by flavin-containing monooxygenase from pig liver
    • Goeger D.E., and Ganther H.E. Oxidation of dimethylselenide to dimethylselenoxide by microsomes from rat liver and lung by flavin-containing monooxygenase from pig liver. Archives of Biochemistry and Biophysics 310 (1994) 448-451
    • (1994) Archives of Biochemistry and Biophysics , vol.310 , pp. 448-451
    • Goeger, D.E.1    Ganther, H.E.2
  • 33
    • 52949089634 scopus 로고    scopus 로고
    • Influence of age and sex on the spontaneous DNA damage detected by Micronucleus test and Comet assay in mice peripheral blood cells
    • Heuser V.D., Andrade V.M., Peres A., Braga L.M.G.M., and Chies J.A.B. Influence of age and sex on the spontaneous DNA damage detected by Micronucleus test and Comet assay in mice peripheral blood cells. Cell Biology International 32 (2008) 1223-1229
    • (2008) Cell Biology International , vol.32 , pp. 1223-1229
    • Heuser, V.D.1    Andrade, V.M.2    Peres, A.3    Braga, L.M.G.M.4    Chies, J.A.B.5
  • 34
    • 0034730525 scopus 로고    scopus 로고
    • Expression of an active Na, K-ATPase with an alpha-subunit lacking all twenty-three native cysteine residues
    • Hu Y.K., Eisses J.F., and Kaplan J.H. Expression of an active Na, K-ATPase with an alpha-subunit lacking all twenty-three native cysteine residues. Journal of Biological Chemistry 275 (2000) 30734-307349
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 30734-307349
    • Hu, Y.K.1    Eisses, J.F.2    Kaplan, J.H.3
  • 35
    • 0020597273 scopus 로고
    • In vitro hemolysis of rat erythrocytes by selenium compounds
    • Hu M.L., and Spallholz J.E. In vitro hemolysis of rat erythrocytes by selenium compounds. Biochemical Pharmacology 32 (1983) 957-961
    • (1983) Biochemical Pharmacology , vol.32 , pp. 957-961
    • Hu, M.L.1    Spallholz, J.E.2
  • 38
    • 9244223093 scopus 로고    scopus 로고
    • Cytometric analysis diphenyl ditelluride of adverse action of on rat thymocytes: cell shrinkage as a cytotoxic parameter
    • Iwase K., Tatsuishi T., Nishimura Y., Yamaguchi J.Y., Oyama Y., Miyoshi N., and Wada M. Cytometric analysis diphenyl ditelluride of adverse action of on rat thymocytes: cell shrinkage as a cytotoxic parameter. Environmental Toxicology 19 (2004) 614-619
    • (2004) Environmental Toxicology , vol.19 , pp. 614-619
    • Iwase, K.1    Tatsuishi, T.2    Nishimura, Y.3    Yamaguchi, J.Y.4    Oyama, Y.5    Miyoshi, N.6    Wada, M.7
  • 39
    • 0020692228 scopus 로고
    • The effect of MDA, a product of lipid peroxidation, on the deformability, dehydration and 51Cr survival of erythrocytes
    • Jain S.K., Mohandas N., Clark M.R., and Shobel S.B. The effect of MDA, a product of lipid peroxidation, on the deformability, dehydration and 51Cr survival of erythrocytes. British Journal of Haematology 53 (1983) 247-252
    • (1983) British Journal of Haematology , vol.53 , pp. 247-252
    • Jain, S.K.1    Mohandas, N.2    Clark, M.R.3    Shobel, S.B.4
  • 40
    • 84984532111 scopus 로고    scopus 로고
    • Comparative studies on dicholesteroyl diselenide and diphenyl diselenide as antioxidant agents and their effect on the activities of Na+/K+ ATPase and delta-aminolevulinic acid dehydratase in the rat brain
    • Kade I.J., Paixão M.W., Rodrigues O.E., Barbosa N.B., Braga A.L., Avila D.S., Nogueira C.W., and Rocha J.B. Comparative studies on dicholesteroyl diselenide and diphenyl diselenide as antioxidant agents and their effect on the activities of Na+/K+ ATPase and delta-aminolevulinic acid dehydratase in the rat brain. Neurochemical Research 33 (2008) 167-178
    • (2008) Neurochemical Research , vol.33 , pp. 167-178
    • Kade, I.J.1    Paixão, M.W.2    Rodrigues, O.E.3    Barbosa, N.B.4    Braga, A.L.5    Avila, D.S.6    Nogueira, C.W.7    Rocha, J.B.8
  • 41
    • 0036889595 scopus 로고    scopus 로고
    • Measurement of erythrocyte lipids, lipid peroxidation, antioxidants and osmotic fragility in cervical cancer patients
    • Kolanjiappana K., Manoharana S., and Kayalvizhib M. Measurement of erythrocyte lipids, lipid peroxidation, antioxidants and osmotic fragility in cervical cancer patients. Clinica Chimica Acta: International Journal of Clinical 326 (2002) 143-149
    • (2002) Clinica Chimica Acta: International Journal of Clinical , vol.326 , pp. 143-149
    • Kolanjiappana, K.1    Manoharana, S.2    Kayalvizhib, M.3
  • 42
    • 0035095366 scopus 로고    scopus 로고
    • Inhibition of human squalene monooxigenase by tellurium compounds: evidence of interaction with vicinal sulfhydryls
    • Laden B.P., and Porter T.D. Inhibition of human squalene monooxigenase by tellurium compounds: evidence of interaction with vicinal sulfhydryls. Journal of Lipid Research 42 (2001) 235-240
    • (2001) Journal of Lipid Research , vol.42 , pp. 235-240
    • Laden, B.P.1    Porter, T.D.2
  • 43
  • 44
    • 0034573619 scopus 로고    scopus 로고
    • Diphenyl diselenide and diphenyl ditelluride differentially affect delta-aminolevulinate dehydratase from liver, kidney, and brain of mice
    • Maciel E.N., Bolzan R.C., Braga A.L., and Rocha J.B.T. Diphenyl diselenide and diphenyl ditelluride differentially affect delta-aminolevulinate dehydratase from liver, kidney, and brain of mice. Journal of Biochemical and Molecular Toxicology 14 (2000) 310-319
    • (2000) Journal of Biochemical and Molecular Toxicology , vol.14 , pp. 310-319
    • Maciel, E.N.1    Bolzan, R.C.2    Braga, A.L.3    Rocha, J.B.T.4
  • 47
    • 28644451437 scopus 로고    scopus 로고
    • Structure-function relationships in the NA+, K+-pump
    • Martin D.W. Structure-function relationships in the NA+, K+-pump. Seminars in Nephrology 25 (2005) 282-291
    • (2005) Seminars in Nephrology , vol.25 , pp. 282-291
    • Martin, D.W.1
  • 49
    • 0030440192 scopus 로고    scopus 로고
    • Schwann cells as targets for neurotoxicants
    • Morell P., and Toews A.D. Schwann cells as targets for neurotoxicants. Neurotoxicology 17 (1996) 685-695
    • (1996) Neurotoxicology , vol.17 , pp. 685-695
    • Morell, P.1    Toews, A.D.2
  • 52
    • 0023832899 scopus 로고
    • A novel biologically active selenooorganic compound-VII. Biotransformation of ebselen in perfused rat liver
    • Müller A., Gabriel H., Sies H., Terlinden R., Fischer H., and Römer A. A novel biologically active selenooorganic compound-VII. Biotransformation of ebselen in perfused rat liver. Biochemical Pharmacology 37 (1988) 1103-1109
    • (1988) Biochemical Pharmacology , vol.37 , pp. 1103-1109
    • Müller, A.1    Gabriel, H.2    Sies, H.3    Terlinden, R.4    Fischer, H.5    Römer, A.6
  • 53
  • 54
    • 84984585825 scopus 로고    scopus 로고
    • Diphenyl diselenide and diphenyl ditelluride affect the rat glutamatergic system in vitro and in vivo
    • Nogueira C.W., Rotta L.N., Perry M.L., Souza D.O., and Rocha J.B.T. Diphenyl diselenide and diphenyl ditelluride affect the rat glutamatergic system in vitro and in vivo. Brain Research 906 (2001) 157-163
    • (2001) Brain Research , vol.906 , pp. 157-163
    • Nogueira, C.W.1    Rotta, L.N.2    Perry, M.L.3    Souza, D.O.4    Rocha, J.B.T.5
  • 55
    • 84984583119 scopus 로고    scopus 로고
    • Organoselenium and organotellurium compounds: toxicology and pharmacology
    • Nogueira C.W., Zeni G., and Rocha J.B.T. Organoselenium and organotellurium compounds: toxicology and pharmacology. Chemical Reviews 104 (2004) 6255-6286
    • (2004) Chemical Reviews , vol.104 , pp. 6255-6286
    • Nogueira, C.W.1    Zeni, G.2    Rocha, J.B.T.3
  • 60
    • 0025214935 scopus 로고
    • Undernutrition during the preweaning period changes calcium ATPase and ADPase activities of synaptosomal fractions of weanling rats
    • Rocha J.B., Mello C.F., Sarkis J.J., and Dias R.D. Undernutrition during the preweaning period changes calcium ATPase and ADPase activities of synaptosomal fractions of weanling rats. The British Journal of Nutrition 63 (1990) 273-283
    • (1990) The British Journal of Nutrition , vol.63 , pp. 273-283
    • Rocha, J.B.1    Mello, C.F.2    Sarkis, J.J.3    Dias, R.D.4
  • 63
    • 33847335444 scopus 로고    scopus 로고
    • Cytotoxic, genotoxic and mutagenic effects of diphenyl diselenide in Chinese hamster lung fibroblasts
    • Rosa R.M., Picada J.N., Saffia J., and Henriques J.A.P. Cytotoxic, genotoxic and mutagenic effects of diphenyl diselenide in Chinese hamster lung fibroblasts. Mutation Research 628 (2007) 87-98
    • (2007) Mutation Research , vol.628 , pp. 87-98
    • Rosa, R.M.1    Picada, J.N.2    Saffia, J.3    Henriques, J.A.P.4
  • 66
    • 0037220272 scopus 로고    scopus 로고
    • Cytometric determination of novel organotellurium compound toxicity in a promyelocytic (HL-60) cell line
    • Sailer B.L., Liles N., Dickerson S., and Chasteen T.G. Cytometric determination of novel organotellurium compound toxicity in a promyelocytic (HL-60) cell line. Archives of Toxicology 77 (2003) 30-36
    • (2003) Archives of Toxicology , vol.77 , pp. 30-36
    • Sailer, B.L.1    Liles, N.2    Dickerson, S.3    Chasteen, T.G.4
  • 67
    • 2342520154 scopus 로고    scopus 로고
    • Chasteen TG. Organotellurium compound toxicity in a promyelocytic cell line compared to non-tellurium-containing organic analog
    • Sailer B.L., Liles N., Dickerson S., and Sumners S. Chasteen TG. Organotellurium compound toxicity in a promyelocytic cell line compared to non-tellurium-containing organic analog. Toxicology In Vitro 18 (2004) 475-482
    • (2004) Toxicology In Vitro , vol.18 , pp. 475-482
    • Sailer, B.L.1    Liles, N.2    Dickerson, S.3    Sumners, S.4
  • 68
    • 84984584169 scopus 로고    scopus 로고
    • Plasmatic vitamin C in nontreated hepatitis C patients is negatively associated with aspartate aminotransferase
    • Santos R.M., Bem A.F., Colpo E., Bertoncello I., Nogueira C.W., and Rocha J.B.T. Plasmatic vitamin C in nontreated hepatitis C patients is negatively associated with aspartate aminotransferase. Liver International 1478 (2008) 54-60
    • (2008) Liver International , vol.1478 , pp. 54-60
    • Santos, R.M.1    Bem, A.F.2    Colpo, E.3    Bertoncello, I.4    Nogueira, C.W.5    Rocha, J.B.T.6
  • 69
    • 84984586800 scopus 로고    scopus 로고
    • Human erythrocyte hemolysis induced by selenium and tellurium compounds increased by GSH or glucose: a possible involvement of reactive oxygen species
    • Schiar V.P.P., Santos D.B., Paixão M.W., Nogueira C.W., Rocha J.B.T., and Zeni G. Human erythrocyte hemolysis induced by selenium and tellurium compounds increased by GSH or glucose: a possible involvement of reactive oxygen species. Chemico-Biological Interactions 177 (2009) 28-33
    • (2009) Chemico-Biological Interactions , vol.177 , pp. 28-33
    • Schiar, V.P.P.1    Santos, D.B.2    Paixão, M.W.3    Nogueira, C.W.4    Rocha, J.B.T.5    Zeni, G.6
  • 71
  • 72
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh N.P., McCoy M.T., Tice R.R., and Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Experimental Cell Research 175 (1988) 184-191
    • (1988) Experimental Cell Research , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 73
    • 84984590221 scopus 로고    scopus 로고
    • Organic and inorganic forms of selenium inhibited differently fish (Rhamdia quelen) and rat (Rattus norvergicus albinus) d-aminolevulinate dehydratase
    • Soares F.A., Farina M., Boettchera A., Braga A.L., and Rocha J.B.T. Organic and inorganic forms of selenium inhibited differently fish (Rhamdia quelen) and rat (Rattus norvergicus albinus) d-aminolevulinate dehydratase. Environmental Research 98 (2005) 46-54
    • (2005) Environmental Research , vol.98 , pp. 46-54
    • Soares, F.A.1    Farina, M.2    Boettchera, A.3    Braga, A.L.4    Rocha, J.B.T.5
  • 75
    • 0033963361 scopus 로고    scopus 로고
    • Effect of three diaryl tellurides, and an organoselenium compound in trout erythrocytes exposed to oxidative stress in vitro
    • Tiano L., Fedeli D., Santroni A.M., Villarini M., Engman L., and Falcioni G. Effect of three diaryl tellurides, and an organoselenium compound in trout erythrocytes exposed to oxidative stress in vitro. Mutation Research 464 (2000) 269-277
    • (2000) Mutation Research , vol.464 , pp. 269-277
    • Tiano, L.1    Fedeli, D.2    Santroni, A.M.3    Villarini, M.4    Engman, L.5    Falcioni, G.6
  • 76
    • 12244258206 scopus 로고    scopus 로고
    • Essentiality and toxicity of selenium and its status in Australia: a review
    • Tinggi U. Essentiality and toxicity of selenium and its status in Australia: a review. Toxicology Letters 137 (2003) 103-110
    • (2003) Toxicology Letters , vol.137 , pp. 103-110
    • Tinggi, U.1
  • 77
    • 0025838253 scopus 로고
    • Tellurium blocks cholesterol synthesis by inhibiting squalene metabolism: preferential vulnerability to this metabolic block leads to peripheral nervous system demyelination
    • Wagner-Recio M., Toews A.D., and Morell P. Tellurium blocks cholesterol synthesis by inhibiting squalene metabolism: preferential vulnerability to this metabolic block leads to peripheral nervous system demyelination. Journal of Neurochemistry 57 (1991) 1891-1901
    • (1991) Journal of Neurochemistry , vol.57 , pp. 1891-1901
    • Wagner-Recio, M.1    Toews, A.D.2    Morell, P.3


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