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Volumn 9, Issue 5, 2009, Pages 577-582

Confirmation of DNA microarray-derived differentially expressed genes in pancreatic cancer using quantitative RT-PCR

Author keywords

Gene expression profiling; Microarray technology; Pancreatic cancer; RT PCR; TGF signaling

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTINEOPLASTIC AGENT; CANCER ANTIBODY; CELL ADHESION MOLECULE; COLLAGEN TYPE 1; FIBRONECTIN; FLUOROURACIL; GELATINASE B; GEMCITABINE; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LAMININ; LIPOCORTIN 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PROTEIN BNIP3; PROTEIN S 100; SCLEROPROTEIN; SMAD PROTEIN; SPHINGOLIPID ACTIVATOR PROTEIN 2; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR MARKER; TUMOR PROMOTER; TUMOR SUPPRESSOR PROTEIN;

EID: 68049108169     PISSN: 14243903     EISSN: 14243911     Source Type: Journal    
DOI: 10.1159/000212084     Document Type: Article
Times cited : (22)

References (55)
  • 1
  • 4
    • 0034032009 scopus 로고    scopus 로고
    • Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: Evidence that DPC4 inactivation occurs late in neoplastic progression
    • Wilentz RE, Iacobuzio-Donahue CA, Argani P, McCarthy DM, Parsons JL, Yeo CJ, Kern SE, Hruban RH: Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression. Cancer Res 2000; 60: 2002-2006.
    • (2000) Cancer Res , vol.60 , pp. 2002-2006
    • Wilentz, R.E.1    Iacobuzio-Donahue, C.A.2    Argani, P.3    McCarthy, D.M.4    Parsons, J.L.5    Yeo, C.J.6    Kern, S.E.7    Hruban, R.H.8
  • 5
    • 0026462778 scopus 로고
    • Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor-α
    • Korc M, Chandrasekar B, Yamanaka Y, Friess H, Buchier M, Beger HG: Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor-α. J Clin Invest 1992; 90: 1352-1360.
    • (1992) J Clin Invest , vol.90 , pp. 1352-1360
    • Korc, M.1    Chandrasekar, B.2    Yamanaka, Y.3    Friess, H.4    Buchier, M.5    Beger, H.G.6
  • 6
    • 0027293748 scopus 로고
    • Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness
    • Yamanaka Y, Friess H, Kobrin MS, Büchler M, Beger HG, Korc M: Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness. Anticancer Res 1993; 13: 565-569.
    • (1993) Anticancer Res , vol.13 , pp. 565-569
    • Yamanaka, Y.1    Friess, H.2    Kobrin, M.S.3    Büchler, M.4    Beger, H.G.5    Korc, M.6
  • 7
    • 0030024411 scopus 로고    scopus 로고
    • Pancreatic cancer: The potential clinical relevance of alterations in growth factors and their receptors
    • Friess H, Berberat P, Schilling M, Kunz J, Korc M, Büchler MW: Pancreatic cancer: The potential clinical relevance of alterations in growth factors and their receptors. J Mol Med 1996; 74: 35-42.
    • (1996) J Mol Med , vol.74 , pp. 35-42
    • Friess, H.1    Berberat, P.2    Schilling, M.3    Kunz, J.4    Korc, M.5    Büchler, M.W.6
  • 8
    • 0028799821 scopus 로고
    • Enhanced erbB-3 expression in human pancreatic cancer correlates with tumor progression
    • Friess H, Yamanaka Y, Kobrin MS, Do DA, Büchler MW, Korc M: Enhanced erbB-3 expression in human pancreatic cancer correlates with tumor progression. Clin Cancer Res 1995; 1: 1413-1420.
    • (1995) Clin Cancer Res , vol.1 , pp. 1413-1420
    • Friess, H.1    Yamanaka, Y.2    Kobrin, M.S.3    Do, D.A.4    Büchler, M.W.5    Korc, M.6
  • 9
    • 0034829649 scopus 로고    scopus 로고
    • Expression of heparin-binding epidermal growth factorlike growth factor in pancreatic adenocarcinoma
    • Ito Y, Higashiyama S, Takeda T, Yamamoto Y, Wakasa KI, Matsuura N: Expression of heparin-binding epidermal growth factorlike growth factor in pancreatic adenocarcinoma. Int J Pancreatol 2001; 29: 47-52.
    • (2001) Int J Pancreatol , vol.29 , pp. 47-52
    • Ito, Y.1    Higashiyama, S.2    Takeda, T.3    Yamamoto, Y.4    Wakasa, K.I.5    Matsuura, N.6
  • 14
    • 33748491517 scopus 로고    scopus 로고
    • MAQC Consortium: The MicroArray Quality Control (MAQC) project shows interand intraplatform reproducibility of gene expression measurements
    • MAQC Consortium: The MicroArray Quality Control (MAQC) project shows interand intraplatform reproducibility of gene expression measurements. Nat Biotechnol 2006; 24: 1151-1161.
    • (2006) Nat Biotechnol , vol.24 , pp. 1151-1161
  • 15
    • 0035208708 scopus 로고    scopus 로고
    • Identification of disease-specific genes in chronic pancreatitis using DNA array technology
    • Friess H, Ding J, Kleeff J, Liao Q, Berberat PO, Hammer J, Büchler MW: Identification of disease-specific genes in chronic pancreatitis using DNA array technology. Ann Surg 2001; 234: 769-779.
    • (2001) Ann Surg , vol.234 , pp. 769-779
    • Friess, H.1    Ding, J.2    Kleeff, J.3    Liao, Q.4    Berberat, P.O.5    Hammer, J.6    Büchler, M.W.7
  • 18
    • 0037093087 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray
    • Han H, Bearss DJ, Browne LW, Calaluce R, Nagle RB, Von Hoff DD: Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray. Cancer Res 2002; 62: 2890-2896.
    • (2002) Cancer Res , vol.62 , pp. 2890-2896
    • Han, H.1    Bearss, D.J.2    Browne, L.W.3    Calaluce, R.4    Nagle, R.B.5    Von Hoff, D.D.6
  • 21
    • 0037962865 scopus 로고    scopus 로고
    • Analysis of gene expression profile of pancreatic carcinoma using cDNA microarray
    • Tan ZJ, Hu XG, Cao GS, Tang Y: Analysis of gene expression profile of pancreatic carcinoma using cDNA microarray. World J Gastroenterol 2003; 9: 818-823. (Pubitemid 36531568)
    • (2003) World Journal of Gastroenterology , vol.9 , Issue.4 , pp. 818-823
    • Tan, Z.-J.1    Hu, X.-G.2    Cao, G.-S.3    Tang, Y.4
  • 22
    • 0038179900 scopus 로고    scopus 로고
    • Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer
    • Logsdon CD, Simeone DM, Binkley C, Arumugam T, Greenson JK, Giordano TJ, Misek DE, Kuick R, Hanash S: Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer. Cancer Res 2003; 63: 2649-2657.
    • (2003) Cancer Res , vol.63 , pp. 2649-2657
    • Logsdon, C.D.1    Simeone, D.M.2    Binkley, C.3    Arumugam, T.4    Greenson, J.K.5    Giordano, T.J.6    Misek, D.E.7    Kuick, R.8    Hanash, S.9
  • 28
  • 30
    • 0034644472 scopus 로고    scopus 로고
    • TGF-β signaling in growth control, cancer, and heritable disorders
    • Massague J, Blain SW, Lo RS: TGF-β signaling in growth control, cancer, and heritable disorders. Cell 2000; 103: 295-309.
    • (2000) Cell , vol.103 , pp. 295-309
    • Massague, J.1    Blain, S.W.2    Lo, R.S.3
  • 31
    • 35348901453 scopus 로고    scopus 로고
    • Basics of TGF-β and pancreatic cancer
    • Truty MJ, Urrutia R: Basics of TGF-β and pancreatic cancer. Pancreatology 2007; 7: 423-435.
    • (2007) Pancreatology , vol.7 , pp. 423-435
    • Truty, M.J.1    Urrutia, R.2
  • 32
    • 0027131252 scopus 로고
    • Enhanced expression of transforming growth factor-β isoforms in pancreatic cancer correlates with decreased survival
    • Friess H, Yamanaka Y, Büchler MW, Ebert M, Beger HG, Gold LI, Korc M: Enhanced expression of transforming growth factor-β isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology 1993; 105: 1846-1856.
    • (1993) Gastroenterology , vol.105 , pp. 1846-1856
    • Friess, H.1    Yamanaka, Y.2    Büchler, M.W.3    Ebert, M.4    Beger, H.G.5    Gold, L.I.6    Korc, M.7
  • 36
    • 0141703513 scopus 로고    scopus 로고
    • Tumor necrosis factor-α -induced IKK phosphorylation of NF-κ B p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway
    • Sakurai H, Suzuki S, Kawasaki N, Nakano H, Okazaki T, Chino A, Doi T, Saiki I: Tumor necrosis factor-α -induced IKK phosphorylation of NF-κ B p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway. J Biol Chem 2003; 278: 36916-36923.
    • (2003) J Biol Chem , vol.278 , pp. 36916-36923
    • Sakurai, H.1    Suzuki, S.2    Kawasaki, N.3    Nakano, H.4    Okazaki, T.5    Chino, A.6    Doi, T.7    Saiki, I.8
  • 37
    • 14844295421 scopus 로고    scopus 로고
    • Critical roles of threonine- 187 phosphorylation in cellular stressinduced rapid and transient activation of transforming growth factor-β -activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2
    • Singhirunnusorn P, Suzuki S, Kawasaki N, Saiki I, Sakurai H: Critical roles of threonine- 187 phosphorylation in cellular stressinduced rapid and transient activation of transforming growth factor-β -activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2. J Biol Chem 2005; 280: 7359-7368.
    • (2005) J Biol Chem , vol.280 , pp. 7359-7368
    • Singhirunnusorn, P.1    Suzuki, S.2    Kawasaki, N.3    Saiki, I.4    Sakurai, H.5
  • 38
    • 25844459154 scopus 로고    scopus 로고
    • NF-κ B: Linking inflammation and immunity to cancer development and progression
    • Karin M, Greten FR: NF-κ B: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol 2005; 5: 749-759.
    • (2005) Nat Rev Immunol , vol.5 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 39
    • 39749195549 scopus 로고    scopus 로고
    • 1 -mediated regulation of matrix metalloproteinase-9 and metastasis
    • 1 -mediated regulation of matrix metalloproteinase-9 and metastasis. Oncogene 2008; 27: 1198-1207.
    • (2008) Oncogene , vol.27 , pp. 1198-1207
    • Safina, A.1    Ren, M.Q.2    Vandette, E.3    Bakin, A.V.4
  • 41
    • 33646363800 scopus 로고    scopus 로고
    • TAK1-mediated stress signaling pathways are essential for TNF-α -promoted pulmonary metastasis of murine colon cancer cells
    • Choo MK, Sakurai H, Koizumi K, Saiki I: TAK1-mediated stress signaling pathways are essential for TNF-α -promoted pulmonary metastasis of murine colon cancer cells. Int J Cancer 2006; 118: 2758-2764.
    • (2006) Int J Cancer , vol.118 , pp. 2758-2764
    • Choo, M.K.1    Sakurai, H.2    Koizumi, K.3    Saiki, I.4
  • 46
  • 48
    • 19844383074 scopus 로고    scopus 로고
    • Periostin induction in tumor cell line explants and inhibition of in vitro cell growth by anti-periostin antibodies
    • Tai IT, Dai M, Chen LB: Periostin induction in tumor cell line explants and inhibition of in vitro cell growth by anti-periostin antibodies. Carcinogenesis 2005; 26: 908-915.
    • (2005) Carcinogenesis , vol.26 , pp. 908-915
    • Tai, I.T.1    Dai, M.2    Chen, L.B.3
  • 49
    • 24344498285 scopus 로고    scopus 로고
    • Periostin is down-regulated in high grade human bladder cancers and suppresses in vitro cell invasiveness and in vivo metastasis of cancer cells
    • Kim CJ, Yoshioka N, Tambe Y, Kushima R, Okada Y, Inoue H: Periostin is down-regulated in high grade human bladder cancers and suppresses in vitro cell invasiveness and in vivo metastasis of cancer cells. Int J Cancer 2005; 117: 51-58.
    • (2005) Int J Cancer , vol.117 , pp. 51-58
    • Kim, C.J.1    Yoshioka, N.2    Tambe, Y.3    Kushima, R.4    Okada, Y.5    Inoue, H.6
  • 53
    • 3442888541 scopus 로고    scopus 로고
    • Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer
    • Okami J, Simeone DM, Logsdon CD: Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer. Cancer Res 2004; 64: 5338-5346.
    • (2004) Cancer Res , vol.64 , pp. 5338-5346
    • Okami, J.1    Simeone, D.M.2    Logsdon, C.D.3
  • 55
    • 21744434389 scopus 로고    scopus 로고
    • Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis
    • Erkan M, Kleeff J, Esposito I, Giese T, Ketterer K, Büchler MW, Giese NA, Friess H: Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis. Oncogene 2005; 24: 4421-4432.
    • (2005) Oncogene , vol.24 , pp. 4421-4432
    • Erkan, M.1    Kleeff, J.2    Esposito, I.3    Giese, T.4    Ketterer, K.5    Büchler, M.W.6    Giese, N.A.7    Friess, H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.