-
1
-
-
0024292722
-
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
-
Almoguera C, Shibata D, Forrester K, Martin J, Arnheim N, Perucho M: Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell 1988; 53: 549-554.
-
(1988)
Cell
, vol.53
, pp. 549-554
-
-
Almoguera, C.1
Shibata, D.2
Forrester, K.3
Martin, J.4
Arnheim, N.5
Perucho, M.6
-
2
-
-
0028059330
-
Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
-
Caldas C, Hahn SA, da Costa LT, Redston MS, Schutte M, Seymour AB, Weinstein CL, Hruban RH, Yeo CJ, Kern SE: Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma. Nat Genet 1994; 8: 27-32.
-
(1994)
Nat Genet
, vol.8
, pp. 27-32
-
-
Caldas, C.1
Hahn, S.A.2
Da Costa, L.T.3
Redston, M.S.4
Schutte, M.5
Seymour, A.B.6
Weinstein, C.L.7
Hruban, R.H.8
Yeo, C.J.9
Kern, S.E.10
-
3
-
-
0027743438
-
Pancreatic adenocarcinomas frequently show p53 gene mutations
-
Scarpa A, Capelli P, Mukai K, Zamboni G, Oda T, Iacono C, Hirohashi S: Pancreatic adenocarcinomas frequently show p53 gene mutations. Am J Pathol 1993; 142: 1534-1543.
-
(1993)
Am J Pathol
, vol.142
, pp. 1534-1543
-
-
Scarpa, A.1
Capelli, P.2
Mukai, K.3
Zamboni, G.4
Oda, T.5
Iacono, C.6
Hirohashi, S.7
-
4
-
-
0034032009
-
Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: Evidence that DPC4 inactivation occurs late in neoplastic progression
-
Wilentz RE, Iacobuzio-Donahue CA, Argani P, McCarthy DM, Parsons JL, Yeo CJ, Kern SE, Hruban RH: Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression. Cancer Res 2000; 60: 2002-2006.
-
(2000)
Cancer Res
, vol.60
, pp. 2002-2006
-
-
Wilentz, R.E.1
Iacobuzio-Donahue, C.A.2
Argani, P.3
McCarthy, D.M.4
Parsons, J.L.5
Yeo, C.J.6
Kern, S.E.7
Hruban, R.H.8
-
5
-
-
0026462778
-
Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor-α
-
Korc M, Chandrasekar B, Yamanaka Y, Friess H, Buchier M, Beger HG: Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor-α. J Clin Invest 1992; 90: 1352-1360.
-
(1992)
J Clin Invest
, vol.90
, pp. 1352-1360
-
-
Korc, M.1
Chandrasekar, B.2
Yamanaka, Y.3
Friess, H.4
Buchier, M.5
Beger, H.G.6
-
6
-
-
0027293748
-
Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness
-
Yamanaka Y, Friess H, Kobrin MS, Büchler M, Beger HG, Korc M: Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness. Anticancer Res 1993; 13: 565-569.
-
(1993)
Anticancer Res
, vol.13
, pp. 565-569
-
-
Yamanaka, Y.1
Friess, H.2
Kobrin, M.S.3
Büchler, M.4
Beger, H.G.5
Korc, M.6
-
7
-
-
0030024411
-
Pancreatic cancer: The potential clinical relevance of alterations in growth factors and their receptors
-
Friess H, Berberat P, Schilling M, Kunz J, Korc M, Büchler MW: Pancreatic cancer: The potential clinical relevance of alterations in growth factors and their receptors. J Mol Med 1996; 74: 35-42.
-
(1996)
J Mol Med
, vol.74
, pp. 35-42
-
-
Friess, H.1
Berberat, P.2
Schilling, M.3
Kunz, J.4
Korc, M.5
Büchler, M.W.6
-
8
-
-
0028799821
-
Enhanced erbB-3 expression in human pancreatic cancer correlates with tumor progression
-
Friess H, Yamanaka Y, Kobrin MS, Do DA, Büchler MW, Korc M: Enhanced erbB-3 expression in human pancreatic cancer correlates with tumor progression. Clin Cancer Res 1995; 1: 1413-1420.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 1413-1420
-
-
Friess, H.1
Yamanaka, Y.2
Kobrin, M.S.3
Do, D.A.4
Büchler, M.W.5
Korc, M.6
-
9
-
-
0034829649
-
Expression of heparin-binding epidermal growth factorlike growth factor in pancreatic adenocarcinoma
-
Ito Y, Higashiyama S, Takeda T, Yamamoto Y, Wakasa KI, Matsuura N: Expression of heparin-binding epidermal growth factorlike growth factor in pancreatic adenocarcinoma. Int J Pancreatol 2001; 29: 47-52.
-
(2001)
Int J Pancreatol
, vol.29
, pp. 47-52
-
-
Ito, Y.1
Higashiyama, S.2
Takeda, T.3
Yamamoto, Y.4
Wakasa, K.I.5
Matsuura, N.6
-
10
-
-
0034647713
-
Epiregulin is up-regulated in pancreatic cancer and stimulates pancreatic cancer cell growth
-
Zhu Z, Kleeff J, Friess H, Wang L, Zimmermann A, Yarden Y, Büchler MW, Korc M: Epiregulin is up-regulated in pancreatic cancer and stimulates pancreatic cancer cell growth. Biochem Biophys Res Commun 2000; 273: 1019-1024.
-
(2000)
Biochem Biophys Res Commun
, vol.273
, pp. 1019-1024
-
-
Zhu, Z.1
Kleeff, J.2
Friess, H.3
Wang, L.4
Zimmermann, A.5
Yarden, Y.6
Büchler, M.W.7
Korc, M.8
-
11
-
-
0033388699
-
Immunohistochemical localization of betacellulin, a new member of the EGF family, in normal human pancreas and islet tumor cells
-
Miyagawa J, Hanafusa O, Sasada R, Yamamoto K, Igarashi K, Yamamori K, Seno M, Tada H, Nammo T, Li M, Yamagata K, Nakajima H, Namba M, Kuwajima M, Matsuzawa Y: Immunohistochemical localization of betacellulin, a new member of the EGF family, in normal human pancreas and islet tumor cells. Endocr J 1999; 46: 755-764.
-
(1999)
Endocr J
, vol.46
, pp. 755-764
-
-
Miyagawa, J.1
Hanafusa, O.2
Sasada, R.3
Yamamoto, K.4
Igarashi, K.5
Yamamori, K.6
Seno, M.7
Tada, H.8
Nammo, T.9
Li, M.10
Yamagata, K.11
Nakajima, H.12
Namba, M.13
Kuwajima, M.14
Matsuzawa, Y.15
-
12
-
-
0028101982
-
Induction and expression of amphiregulin in human pancreatic cancer
-
Ebert M, Yokoyama M, Kobrin MS, Friess H, Lopez ME, Büchler MW, Johnson GR, Korc M: Induction and expression of amphiregulin in human pancreatic cancer. Cancer Res 1994; 54: 3959-3962.
-
(1994)
Cancer Res
, vol.54
, pp. 3959-3962
-
-
Ebert, M.1
Yokoyama, M.2
Kobrin, M.S.3
Friess, H.4
Lopez, M.E.5
Büchler, M.W.6
Johnson, G.R.7
Korc, M.8
-
13
-
-
33845691807
-
Expression and differential signaling of heregulins in pancreatic cancer cells
-
Kolb A, Kleeff J, Arnold N, Giese NA, Giese T, Korc M, Friess H: Expression and differential signaling of heregulins in pancreatic cancer cells. Int J Cancer 2007; 120: 514-523.
-
(2007)
Int J Cancer
, vol.120
, pp. 514-523
-
-
Kolb, A.1
Kleeff, J.2
Arnold, N.3
Giese, N.A.4
Giese, T.5
Korc, M.6
Friess, H.7
-
14
-
-
33748491517
-
MAQC Consortium: The MicroArray Quality Control (MAQC) project shows interand intraplatform reproducibility of gene expression measurements
-
MAQC Consortium: The MicroArray Quality Control (MAQC) project shows interand intraplatform reproducibility of gene expression measurements. Nat Biotechnol 2006; 24: 1151-1161.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1151-1161
-
-
-
15
-
-
0035208708
-
Identification of disease-specific genes in chronic pancreatitis using DNA array technology
-
Friess H, Ding J, Kleeff J, Liao Q, Berberat PO, Hammer J, Büchler MW: Identification of disease-specific genes in chronic pancreatitis using DNA array technology. Ann Surg 2001; 234: 769-779.
-
(2001)
Ann Surg
, vol.234
, pp. 769-779
-
-
Friess, H.1
Ding, J.2
Kleeff, J.3
Liao, Q.4
Berberat, P.O.5
Hammer, J.6
Büchler, M.W.7
-
16
-
-
0038047893
-
Microarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancer
-
Friess H, Ding J, Kleeff J, Fenkell L, Rosinski JA, Guweidhi A, Reidhaar-Olson JF, Korc M, Hammer J, Büchler MW: Microarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancer. Cell Mol Life Sci 2003; 60: 1180-1199.
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 1180-1199
-
-
Friess, H.1
Ding, J.2
Kleeff, J.3
Fenkell, L.4
Rosinski, J.A.5
Guweidhi, A.6
Reidhaar-Olson, J.F.7
Korc, M.8
Hammer, J.9
Büchler, M.W.10
-
17
-
-
27144454969
-
Transcriptome analysis of microdissected pancreatic intraepithelial neoplastic lesions
-
Buchholz M, Braun M, Heidenblut A, Kestler HA, Kloppel G, Schmiegel W, Hahn SA, Luttges J, Gress TM: Transcriptome analysis of microdissected pancreatic intraepithelial neoplastic lesions. Oncogene 2005; 24: 6626-6636.
-
(2005)
Oncogene
, vol.24
, pp. 6626-6636
-
-
Buchholz, M.1
Braun, M.2
Heidenblut, A.3
Kestler, H.A.4
Kloppel, G.5
Schmiegel, W.6
Hahn, S.A.7
Luttges, J.8
Gress, T.M.9
-
18
-
-
0037093087
-
Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray
-
Han H, Bearss DJ, Browne LW, Calaluce R, Nagle RB, Von Hoff DD: Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray. Cancer Res 2002; 62: 2890-2896.
-
(2002)
Cancer Res
, vol.62
, pp. 2890-2896
-
-
Han, H.1
Bearss, D.J.2
Browne, L.W.3
Calaluce, R.4
Nagle, R.B.5
Von Hoff, D.D.6
-
19
-
-
9144241047
-
Highly expressed genes in pancreatic ductal adenocarcinomas: A comprehensive characterization and comparison of the transcription profiles obtained from three major technologies
-
Iacobuzio-Donahue CA, Ashfaq R, Maitra A, Adsay NV, Shen-Ong GL, Berg K, Hollingsworth MA, Cameron JL, Yeo CJ, Kern SE, Goggins M, Hruban RH: Highly expressed genes in pancreatic ductal adenocarcinomas: A comprehensive characterization and comparison of the transcription profiles obtained from three major technologies. Cancer Res 2003; 63: 8614-8622.
-
(2003)
Cancer Res
, vol.63
, pp. 8614-8622
-
-
Iacobuzio-Donahue, C.A.1
Ashfaq, R.2
Maitra, A.3
Adsay, N.V.4
Shen-Ong, G.L.5
Berg, K.6
Hollingsworth, M.A.7
Cameron, J.L.8
Yeo, C.J.9
Kern, S.E.10
Goggins, M.11
Hruban, R.H.12
-
20
-
-
0036107889
-
Discovery of novel tumor markers of pancreatic cancer using global gene expression technology
-
Iacobuzio-Donahue CA, Maitra A, Shen- Ong GL, van Heek T, Ashfaq R, Meyer R, Walter K, Berg K, Hollingsworth MA, Cameron JL, Yeo CJ, Kern SE, Goggins M, Hruban RH: Discovery of novel tumor markers of pancreatic cancer using global gene expression technology. Am J Pathol 2002; 160: 1239-1249.
-
(2002)
Am J Pathol
, vol.160
, pp. 1239-1249
-
-
Iacobuzio-Donahue, C.A.1
Maitra, A.2
Shen- Ong, G.L.3
Van Heek, T.4
Ashfaq, R.5
Meyer, R.6
Walter, K.7
Berg, K.8
Hollingsworth, M.A.9
Cameron, J.L.10
Yeo, C.J.11
Kern, S.E.12
Goggins, M.13
Hruban, R.H.14
-
21
-
-
0037962865
-
Analysis of gene expression profile of pancreatic carcinoma using cDNA microarray
-
Tan ZJ, Hu XG, Cao GS, Tang Y: Analysis of gene expression profile of pancreatic carcinoma using cDNA microarray. World J Gastroenterol 2003; 9: 818-823. (Pubitemid 36531568)
-
(2003)
World Journal of Gastroenterology
, vol.9
, Issue.4
, pp. 818-823
-
-
Tan, Z.-J.1
Hu, X.-G.2
Cao, G.-S.3
Tang, Y.4
-
22
-
-
0038179900
-
Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer
-
Logsdon CD, Simeone DM, Binkley C, Arumugam T, Greenson JK, Giordano TJ, Misek DE, Kuick R, Hanash S: Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer. Cancer Res 2003; 63: 2649-2657.
-
(2003)
Cancer Res
, vol.63
, pp. 2649-2657
-
-
Logsdon, C.D.1
Simeone, D.M.2
Binkley, C.3
Arumugam, T.4
Greenson, J.K.5
Giordano, T.J.6
Misek, D.E.7
Kuick, R.8
Hanash, S.9
-
23
-
-
0242266512
-
Gene expression profiles of microdissected pancreatic ductal adenocarcinoma
-
Grutzmann R, Foerder M, Alldinger I, Staub E, Brummendorf T, Ropcke S, Li X, Kristiansen G, Jesnowski R, Sipos B, Lohr M, Luttges J, Ockert D, Kloppel G, Saeger HD, Pilarsky C: Gene expression profiles of microdissected pancreatic ductal adenocarcinoma. Virchows Arch 2003; 443: 508-517.
-
(2003)
Virchows Arch
, vol.443
, pp. 508-517
-
-
Grutzmann, R.1
Foerder, M.2
Alldinger, I.3
Staub, E.4
Brummendorf, T.5
Ropcke, S.6
Li, X.7
Kristiansen, G.8
Jesnowski, R.9
Sipos, B.10
Lohr, M.11
Luttges, J.12
Ockert, D.13
Kloppel, G.14
Saeger, H.D.15
Pilarsky, C.16
-
24
-
-
0141626696
-
Molecular alterations in pancreatic carcinoma: Expression profiling shows that dysregulated expression of S100 genes is highly prevalent
-
Crnogorac-Jurcevic T, Missiaglia E, Blaveri E, Gangeswaran R, Jones M, Terris B, Costello E, Neoptolemos JP, Lemoine NR: Molecular alterations in pancreatic carcinoma: expression profiling shows that dysregulated expression of S100 genes is highly prevalent. J Pathol 2003; 201: 63-74.
-
(2003)
J Pathol
, vol.201
, pp. 63-74
-
-
Crnogorac-Jurcevic, T.1
Missiaglia, E.2
Blaveri, E.3
Gangeswaran, R.4
Jones, M.5
Terris, B.6
Costello, E.7
Neoptolemos, J.P.8
Lemoine, N.R.9
-
25
-
-
0036098611
-
Characterization of gene expression profiles in intraductal papillary-mucinous tumors of the pancreas
-
Terris B, Blaveri E, Crnogorac-Jurcevic T, Jones M, Missiaglia E, Ruszniewski P, Sauvanet A, Lemoine NR: Characterization of gene expression profiles in intraductal papillary- mucinous tumors of the pancreas. Am J Pathol 2002; 160: 1745-1754. (Pubitemid 34525654)
-
(2002)
American Journal of Pathology
, vol.160
, Issue.5
, pp. 1745-1754
-
-
Terris, B.1
Blaveri, E.2
Crnogorac-Jurcevic, T.3
Jones, M.4
Missiaglia, E.5
Ruszniewski, P.6
Sauvanet, A.7
Lemoine, N.R.8
-
26
-
-
0037379406
-
Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays
-
Iacobuzio-Donahue CA, Maitra A, Olsen M, Lowe AW, van Heek NT, Rosty C, Walter K, Sato N, Parker A, Ashfaq R, Jaffee E, Ryu B, Jones J, Eshleman JR, Yeo CJ, Cameron JL, Kern SE, Hruban RH, Brown PO, Goggins M: Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays. Am J Pathol 2003; 162: 1151-1162.
-
(2003)
Am J Pathol
, vol.162
, pp. 1151-1162
-
-
Iacobuzio-Donahue, C.A.1
Maitra, A.2
Olsen, M.3
Lowe, A.W.4
Van Heek, N.T.5
Rosty, C.6
Walter, K.7
Sato, N.8
Parker, A.9
Ashfaq, R.10
Jaffee, E.11
Ryu, B.12
Jones, J.13
Eshleman, J.R.14
Yeo, C.J.15
Cameron, J.L.16
Kern, S.E.17
Hruban, R.H.18
Brown, P.O.19
Goggins, M.20
more..
-
27
-
-
23744510853
-
Meta-analysis of microarray data on pancreatic cancer defines a set of commonly dysregulated genes
-
Grutzmann R, Boriss H, Ammerpohl O, Luttges J, Kalthoff H, Schackert HK, Kloppel G, Saeger HD, Pilarsky C: Meta-analysis of microarray data on pancreatic cancer defines a set of commonly dysregulated genes. Oncogene 2005; 24: 5079-5088.
-
(2005)
Oncogene
, vol.24
, pp. 5079-5088
-
-
Grutzmann, R.1
Boriss, H.2
Ammerpohl, O.3
Luttges, J.4
Kalthoff, H.5
Schackert, H.K.6
Kloppel, G.7
Saeger, H.D.8
Pilarsky, C.9
-
28
-
-
0036211063
-
Analysis of matched mRNA measurements from two different microarray technologies
-
Kuo WP, Jenssen TK, Butte AJ, Ohno-Machado L, Kohane IS: Analysis of matched mRNA measurements from two different microarray technologies. Bioinformatics 2002; 18: 405-412.
-
(2002)
Bioinformatics
, vol.18
, pp. 405-412
-
-
Kuo, W.P.1
Jenssen, T.K.2
Butte, A.J.3
Ohno-Machado, L.4
Kohane, I.S.5
-
29
-
-
11844263989
-
DNA microarray analysis of pancreatic malignancies
-
Brandt R, Grutzmann R, Bauer A, Jesnowski R, Ringel J, Lohr M, Pilarsky C, Hoheisel JD: DNA microarray analysis of pancreatic malignancies. Pancreatology 2004; 4: 587-597.
-
(2004)
Pancreatology
, vol.4
, pp. 587-597
-
-
Brandt, R.1
Grutzmann, R.2
Bauer, A.3
Jesnowski, R.4
Ringel, J.5
Lohr, M.6
Pilarsky, C.7
Hoheisel, J.D.8
-
30
-
-
0034644472
-
TGF-β signaling in growth control, cancer, and heritable disorders
-
Massague J, Blain SW, Lo RS: TGF-β signaling in growth control, cancer, and heritable disorders. Cell 2000; 103: 295-309.
-
(2000)
Cell
, vol.103
, pp. 295-309
-
-
Massague, J.1
Blain, S.W.2
Lo, R.S.3
-
31
-
-
35348901453
-
Basics of TGF-β and pancreatic cancer
-
Truty MJ, Urrutia R: Basics of TGF-β and pancreatic cancer. Pancreatology 2007; 7: 423-435.
-
(2007)
Pancreatology
, vol.7
, pp. 423-435
-
-
Truty, M.J.1
Urrutia, R.2
-
32
-
-
0027131252
-
Enhanced expression of transforming growth factor-β isoforms in pancreatic cancer correlates with decreased survival
-
Friess H, Yamanaka Y, Büchler MW, Ebert M, Beger HG, Gold LI, Korc M: Enhanced expression of transforming growth factor-β isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology 1993; 105: 1846-1856.
-
(1993)
Gastroenterology
, vol.105
, pp. 1846-1856
-
-
Friess, H.1
Yamanaka, Y.2
Büchler, M.W.3
Ebert, M.4
Beger, H.G.5
Gold, L.I.6
Korc, M.7
-
33
-
-
0032849994
-
1 in human pancreatic cancer
-
1 in human pancreatic cancer. Dig Dis Sci 1999; 44: 1793-1802.
-
(1999)
Dig Dis Sci
, vol.44
, pp. 1793-1802
-
-
Kleeff, J.1
Friess, H.2
Simon, P.3
Susmallian, S.4
Büchler, P.5
Zimmermann, A.6
Büchler, M.W.7
Korc, M.8
-
34
-
-
0033598408
-
The TGF-β signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer
-
Kleeff J, Ishiwata T, Maruyama H, Friess H, Truong P, Büchler MW, Falb D, Korc M: The TGF-β signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer. Oncogene 1999; 18: 5363-5372.
-
(1999)
Oncogene
, vol.18
, pp. 5363-5372
-
-
Kleeff, J.1
Ishiwata, T.2
Maruyama, H.3
Friess, H.4
Truong, P.5
Büchler, M.W.6
Falb, D.7
Korc, M.8
-
35
-
-
0029551805
-
Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction
-
Yamaguchi K, Shirakabe K, Shibuya H, Irie K, Oishi I, Ueno N, Taniguchi T, Nishida E, Matsumoto K: Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction. Science 1995; 270: 2008-2011.
-
(1995)
Science
, vol.270
, pp. 2008-2011
-
-
Yamaguchi, K.1
Shirakabe, K.2
Shibuya, H.3
Irie, K.4
Oishi, I.5
Ueno, N.6
Taniguchi, T.7
Nishida, E.8
Matsumoto, K.9
-
36
-
-
0141703513
-
Tumor necrosis factor-α -induced IKK phosphorylation of NF-κ B p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway
-
Sakurai H, Suzuki S, Kawasaki N, Nakano H, Okazaki T, Chino A, Doi T, Saiki I: Tumor necrosis factor-α -induced IKK phosphorylation of NF-κ B p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway. J Biol Chem 2003; 278: 36916-36923.
-
(2003)
J Biol Chem
, vol.278
, pp. 36916-36923
-
-
Sakurai, H.1
Suzuki, S.2
Kawasaki, N.3
Nakano, H.4
Okazaki, T.5
Chino, A.6
Doi, T.7
Saiki, I.8
-
37
-
-
14844295421
-
Critical roles of threonine- 187 phosphorylation in cellular stressinduced rapid and transient activation of transforming growth factor-β -activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2
-
Singhirunnusorn P, Suzuki S, Kawasaki N, Saiki I, Sakurai H: Critical roles of threonine- 187 phosphorylation in cellular stressinduced rapid and transient activation of transforming growth factor-β -activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2. J Biol Chem 2005; 280: 7359-7368.
-
(2005)
J Biol Chem
, vol.280
, pp. 7359-7368
-
-
Singhirunnusorn, P.1
Suzuki, S.2
Kawasaki, N.3
Saiki, I.4
Sakurai, H.5
-
38
-
-
25844459154
-
NF-κ B: Linking inflammation and immunity to cancer development and progression
-
Karin M, Greten FR: NF-κ B: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol 2005; 5: 749-759.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
40
-
-
34547891037
-
Transcriptional network governing the angiogenic switch in human pancreatic cancer
-
Abdollahi A, Schwager C, Kleeff J, Esposito I, Domhan S, Peschke P, Hauser K, Hahnfeldt P, Hlatky L, Debus J, Peters JM, Friess H, Folkman J, Huber PE: Transcriptional network governing the angiogenic switch in human pancreatic cancer. Proc Natl Acad Sci USA 2007; 104: 12890-12895.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12890-12895
-
-
Abdollahi, A.1
Schwager, C.2
Kleeff, J.3
Esposito, I.4
Domhan, S.5
Peschke, P.6
Hauser, K.7
Hahnfeldt, P.8
Hlatky, L.9
Debus, J.10
Peters, J.M.11
Friess, H.12
Folkman, J.13
Huber, P.E.14
-
41
-
-
33646363800
-
TAK1-mediated stress signaling pathways are essential for TNF-α -promoted pulmonary metastasis of murine colon cancer cells
-
Choo MK, Sakurai H, Koizumi K, Saiki I: TAK1-mediated stress signaling pathways are essential for TNF-α -promoted pulmonary metastasis of murine colon cancer cells. Int J Cancer 2006; 118: 2758-2764.
-
(2006)
Int J Cancer
, vol.118
, pp. 2758-2764
-
-
Choo, M.K.1
Sakurai, H.2
Koizumi, K.3
Saiki, I.4
-
42
-
-
5444247172
-
Identification, culture, and characterization of pancreatic stellate cells in rats and humans
-
Bachem MG, Schneider E, Gross H, Weidenbach H, Schmid RM, Menke A, Siech M, Beger H, Grunert A, Adler G: Identification, culture, and characterization of pancreatic stellate cells in rats and humans. Gastroenterology 1998; 115: 421-432.
-
(1998)
Gastroenterology
, vol.115
, pp. 421-432
-
-
Bachem, M.G.1
Schneider, E.2
Gross, H.3
Weidenbach, H.4
Schmid, R.M.5
Menke, A.6
Siech, M.7
Beger, H.8
Grunert, A.9
Adler, G.10
-
43
-
-
0032954505
-
Pancreatic stellate cells are activated by proinflammatory cytokines: Implications for pancreatic fibrogenesis
-
Apte MV, Haber PS, Darby SJ, Rodgers SC, McCaughan GW, Korsten MA, Pirola RC, Wilson JS: Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis. Gut 1999; 44: 534-541.
-
(1999)
Gut
, vol.44
, pp. 534-541
-
-
Apte, M.V.1
Haber, P.S.2
Darby, S.J.3
Rodgers, S.C.4
McCaughan, G.W.5
Korsten, M.A.6
Pirola, R.C.7
Wilson, J.S.8
-
44
-
-
0028157921
-
Human ductal adenocarcinomas of the pancreas express extracellular matrix proteins
-
Lohr M, Trautmann B, Gottler M, Peters S, Zauner I, Maillet B, Kloppel G: Human ductal adenocarcinomas of the pancreas express extracellular matrix proteins. Br J Cancer 1994; 69: 144-151.
-
(1994)
Br J Cancer
, vol.69
, pp. 144-151
-
-
Lohr, M.1
Trautmann, B.2
Gottler, M.3
Peters, S.4
Zauner, I.5
Maillet, B.6
Kloppel, G.7
-
46
-
-
11144357346
-
Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway
-
Bao S, Ouyang G, Bai X, Huang Z, Ma C, Liu M, Shao R, Anderson RM, Rich JN, Wang XF: Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway. Cancer Cell 2004; 5: 329-339.
-
(2004)
Cancer Cell
, vol.5
, pp. 329-339
-
-
Bao, S.1
Ouyang, G.2
Bai, X.3
Huang, Z.4
Ma, C.5
Liu, M.6
Shao, R.7
Anderson, R.M.8
Rich, J.N.9
Wang, X.F.10
-
48
-
-
19844383074
-
Periostin induction in tumor cell line explants and inhibition of in vitro cell growth by anti-periostin antibodies
-
Tai IT, Dai M, Chen LB: Periostin induction in tumor cell line explants and inhibition of in vitro cell growth by anti-periostin antibodies. Carcinogenesis 2005; 26: 908-915.
-
(2005)
Carcinogenesis
, vol.26
, pp. 908-915
-
-
Tai, I.T.1
Dai, M.2
Chen, L.B.3
-
49
-
-
24344498285
-
Periostin is down-regulated in high grade human bladder cancers and suppresses in vitro cell invasiveness and in vivo metastasis of cancer cells
-
Kim CJ, Yoshioka N, Tambe Y, Kushima R, Okada Y, Inoue H: Periostin is down-regulated in high grade human bladder cancers and suppresses in vitro cell invasiveness and in vivo metastasis of cancer cells. Int J Cancer 2005; 117: 51-58.
-
(2005)
Int J Cancer
, vol.117
, pp. 51-58
-
-
Kim, C.J.1
Yoshioka, N.2
Tambe, Y.3
Kushima, R.4
Okada, Y.5
Inoue, H.6
-
50
-
-
0036382936
-
Suppression of anchorage-independent growth of human cancer cell lines by the TRIF52/periostin/OSF-2 gene
-
Yoshioka N, Fuji S, Shimakage M, Kodama K, Hakura A, Yutsudo M, Inoue H, Nojima H: Suppression of anchorage-independent growth of human cancer cell lines by the TRIF52/periostin/OSF-2 gene. Exp Cell Res 2002; 279: 91-99.
-
(2002)
Exp Cell Res
, vol.279
, pp. 91-99
-
-
Yoshioka, N.1
Fuji, S.2
Shimakage, M.3
Kodama, K.4
Hakura, A.5
Yutsudo, M.6
Inoue, H.7
Nojima, H.8
-
51
-
-
10744219705
-
Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes
-
Amatschek S, Koenig U, Auer H, Steinlein P, Pacher M, Gruenfelder A, Dekan G, Vogl S, Kubista E, Heider KH, Stratowa C, Schreiber M, Sommergruber W: Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes. Cancer Res 2004; 64: 844-856.
-
(2004)
Cancer Res
, vol.64
, pp. 844-856
-
-
Amatschek, S.1
Koenig, U.2
Auer, H.3
Steinlein, P.4
Pacher, M.5
Gruenfelder, A.6
Dekan, G.7
Vogl, S.8
Kubista, E.9
Heider, K.H.10
Stratowa, C.11
Schreiber, M.12
Sommergruber, W.13
-
52
-
-
34247236139
-
Periostin creates a tumor- supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity
-
Erkan M, Kleeff J, Gorbachevski A, Reiser C, Mitkus T, Esposito I, Giese T, Büchler MW, Giese NA, Friess H: Periostin creates a tumor- supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity. Gastroenterology 2007; 132: 1447-1464.
-
(2007)
Gastroenterology
, vol.132
, pp. 1447-1464
-
-
Erkan, M.1
Kleeff, J.2
Gorbachevski, A.3
Reiser, C.4
Mitkus, T.5
Esposito, I.6
Giese, T.7
Büchler, M.W.8
Giese, N.A.9
Friess, H.10
-
53
-
-
3442888541
-
Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer
-
Okami J, Simeone DM, Logsdon CD: Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer. Cancer Res 2004; 64: 5338-5346.
-
(2004)
Cancer Res
, vol.64
, pp. 5338-5346
-
-
Okami, J.1
Simeone, D.M.2
Logsdon, C.D.3
-
54
-
-
20444437669
-
Upregulation of BNIP3 by 5-aza- 2′ -deoxycytidine sensitizes pancreatic cancer cells to hypoxia-mediated cell death
-
Abe T, Toyota M, Suzuki H, Murai M, Akino K, Ueno M, Nojima M, Yawata A, Miyakawa H, Suga T, Ito H, Endo T, Tokino T, Hinoda Y, Imai K: Upregulation of BNIP3 by 5-aza- 2′ -deoxycytidine sensitizes pancreatic cancer cells to hypoxia-mediated cell death. J Gastroenterol 2005; 40: 504-510.
-
(2005)
J Gastroenterol
, vol.40
, pp. 504-510
-
-
Abe, T.1
Toyota, M.2
Suzuki, H.3
Murai, M.4
Akino, K.5
Ueno, M.6
Nojima, M.7
Yawata, A.8
Miyakawa, H.9
Suga, T.10
Ito, H.11
Endo, T.12
Tokino, T.13
Hinoda, Y.14
Imai, K.15
-
55
-
-
21744434389
-
Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis
-
Erkan M, Kleeff J, Esposito I, Giese T, Ketterer K, Büchler MW, Giese NA, Friess H: Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis. Oncogene 2005; 24: 4421-4432.
-
(2005)
Oncogene
, vol.24
, pp. 4421-4432
-
-
Erkan, M.1
Kleeff, J.2
Esposito, I.3
Giese, T.4
Ketterer, K.5
Büchler, M.W.6
Giese, N.A.7
Friess, H.8
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