The efficacy of a novel chitosan gel on hemostasis after endoscopic sinus surgery in a sheep model of chronic rhinosinusitis

American Journal of Rhinology and Allergy

Volumn 23, Issue 1, 2009, Pages 71-75

  Valentine, Rowan ^a   Athanasiadis, Theo ^a   Moratti, Stephen ^b   Robinson, Simon ^c   Wormald, Peter John ^a,d  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c Wakefield Hospital   (New Zealand)

^d QUEEN ELIZABETH HOSPITAL   (Australia)

Author keywords

Chitosan; Chronic rhinosinusitis; Dextran; Endoscopic sinus surgery; Gel application; Hemostasis; Sheep; Wound healing

Indexed keywords

CHITOSAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BOEZAART SURGICAL FIELD GRADING SCALE; CHRONIC RHINOSINUSITIS; CONTROLLED STUDY; DRUG EFFICACY; ENDOSCOPIC SINUS SURGERY; EPISTAXIS; ESTRUS; ETHMOID BONE; GASTRIC SUCTION; GEL; HEMOSTASIS; IN VIVO STUDY; MORTALITY; MUCOSAL DISEASE; NONHUMAN; NOSE SURGERY; POSTOPERATIVE PERIOD; RHINOSINUSITIS; SCORING SYSTEM; SHEEP; VIDEOENDOSCOPY;

ADMINISTRATION, INTRANASAL; ANIMALS; CHITOSAN; DISEASE MODELS, ANIMAL; ENDOSCOPY; ETHMOID SINUSITIS; GELS; HEMOSTASIS, ENDOSCOPIC; HEMOSTATICS; OTORHINOLARYNGOLOGIC SURGICAL PROCEDURES; POSTOPERATIVE HEMORRHAGE; RHINITIS; SHEEP; VIDEO RECORDING;

EID: 68049102477     PISSN: 19458924     EISSN: 19458932     Source Type: Journal    
DOI: 10.2500/ajra.2009.23.3266     Document Type: Article

References (45)

1. Wormald P-J. Setup and ergonomics of endoscopic sinus surgery. In Endoscopic Sinus Surgery - Anatomy, Three-Dimensional Reconstruction, and Surgical Technique. Chap. 1 New York: Thieme, 2005.
2. Meltzer E, Hamilos D, and Hadley J. Rhinosinusitis: Establishing definitions for clinical research and patient care. J Allergy Clin Immunol 114:155-212, 2004.
3. Von Schoenberg M, Robinson P, and Ryan R. Nasal packing after routine nasal surgery: Is it justified? J Laryngol Otol 107:902-905, 1993.
4. Samad I, Stevens HE, and Maloney A. The efficacy of nasal septal surgery. J Otolaryngol 21:88-91, 1992.
5. Dowley AC, and Strachan DR. Allergy to Merocel nasal packs causing septal perforation and inferior turbinate necrosis. J Laryngol Otol 115:735, 2001.
6. Nahass RG, and Gocke DJ. Toxic shock syndrome associated with use of a nasal tampon. Am J Rhinol 84:629-631, 1988.
7. Shikani AH. Use of antibiotics for expansion of Merocel packing following endoscopic sinus surgery. ENT J 108:564-566, 1996.
8. Shaw CL, Dymock RB, Cowin A, and Wormald P-J. Effect of packing on the nasal mucosa of sheep. J Laryngol Otol 114:506-509, 2000.
9. Pomerantz J, and Dutton JM. Platelet gel for endoscopic sinus surgery. Ann Otol Rhinol Laryngol 114:699-704, 2005.
10. Pusateri AE, McCarthy SJ, Gregory KW, et al. Effect of a chitosan-based hemostatic dressing on blood loss and survival in a model of severe venous hemorrhage and hepatic injury in swine. J Trauma 54:177-182, 2003.
11. Pusateri AE, Holcomb JB, Kheirabadi BS, et al. Making sense of the preclinical literature on advanced hemostatic products. J Trauma 60:674-682, 2006.
12. Klokkevold PR, Fukayama H, Sund EC, and Bertolami CN. The effects of chitosan (poly-N-acetyl glucosamine) on lingual hemostasis in heparinised rabbits. J Oral Maxillofac Surg 57:49-52, 1999.
13. Klokkevold PR, Lew DS, Ellis DG, and Bertolami CN. The effect of chitosan on lingual hemostasis in rabbits. J Oral Maxillofac Surg 49:858-863, 1991.
14. Klokkevold PR, Subuar P, Fukayama H, and Bertolami CN. Effect of chitosan on lingual hemostasis in rabbits with platelet dysfunction induced by epoprostenol. J Oral Maxillofac Surg 50:41-45, 1992.
15. Hirano S, Zhang M, Nakagawa M, and Miyata T. Wet spun chitosan-collagen fibers, their chemical N-modifications, and blood compatibility. Biomaterials 21:997-1003, 2000.
16. Rao SB, and Sharma CP. Use of chitosan as a biomaterial: Studies on its safety and hemostatic potential. J Biomed Mater Res 34:21-28, 1997.
17. Dutkiewicz JK. Superabsorbent materials from shellfish waste - A review. J Biomed Mater Res 63:373-381, 2002.
18. Chou TC, Fu E, Wu CJ, and Yeh JH. Chitosan enhances platelet adhesion and aggregation. Biochem Biophys Res Commun 302:480-483, 2003.
19. Brandenberg G, Leibrock LG, Shuman R, et al. Chitosan: A new topical hemostatic agent for diffuse capillary bleeding in brain tissue. Neurosurgery 15:9-13, 1984.
20. Aguilera L, Bildrell R, Fulkerson P, et al. Chitosan dressing provides hemostasis in swine femoral arterial injury model. Preshosp Emerg Care 11:172-178, 2007.
21. Connolly RJ. Application of the poly-N-acetyl glucosamine-derived rapid deployment hemostat trauma dressing in severe/lethal swine hemorrhage trauma models. J Trauma 57:S26-S28, 2004.
22. Wedmore I, McManus JG, Pusateri AE, and Holcomb JB. A special report on the chitosan-based hemostatic dressing: experience in current combat operations. J Trauma 60:655-658, 2006.
23. Muzzarelli RAA. Chitin and chitosan: Unique cationic polysaccharides. In Encyclopedia of Polymer Science and Engineering, Mark HF, Bikales N, Overberger CG, Menges G, and Kroschwitz JI (Eds.), Hoboken, NJ: Wiley Interscience. 1990. 430.
24. Lee D, Powers K, and Braney R. Physicochemical properties and blood compatibility of acylated chitosan nanoparticles. Carbohydr Polym 58:371-377, 2004.
25. Lee KY, Ha WS, and Park WH. Blood Compatibility and biodegradability of partially N-acylated chitosan derivatives. Biomaterials 16:1211-1216, 1995.
26. Ishihara M, Nakanishi K, Ono K, et al. Photocrosslinkable chitosan as a dressing for wound occlusion and accelerator in healing process. Biomaterials 3:833-840, 2002.
27. Kurita K. Chitin and chitosan: Functional biopolymers from marine crustaceans. Mar Biotechnol (NY) 8:203-226, 2006.
28. Boezaart AP, Van Der Merwe J, and Coetzee A. Comparison of sodium nitroprusside and esmolol induced controlled hypotension for functional endoscopic sinus surgery. Can J Anaesth 42:373-376, 1995.
29. Orlandi RR. Biomaterials for sinus implantation. Curr Opin Otolaryngol Head Neck Surg 15:44-47, 2007.
30. Athanasiadis T, Beule AG, and Wormald PJ. Effects of topical antifibrinolytics in endoscopic sinus surgery: A pilot randomized controlled trial. Am J Rhinol 21:737-742, 2007.
31. Athanasiadis T, Beule AG, and Wormald PJ. Effects of topical antifibrinolytics in endoscopic sinus surgery: A pilot randomized controlled trial. Am J Rhinol 21:737-742, 2007.
32. Gall RM, Witterick IJ, Shargill NS, and Hawke M. Control of bleeding in endoscopic sinus surgery: Use of a novel gelatin-based hemostatic agent. J Otolaryngol 31:271-274, 2002.
33. Chandra RK, Conley MD, and Kern RC. The effect of FloSeal on mucosal healing after endoscopic sinus surgery: A comparison with thrombin-soaked gelatin foam. Am J Rhinol 17:51-55, 2003.
34. Chandra RK, Conley MD, Haines GK, and Kern RC. Long-term effects of FloSeal packing after endoscopic sinus surgery. Am J Rhinol 19:240-243, 2005.
35. Vaiman M, Eviatar E, Shlamkovick N, and Segal S. Use of fibrin glue as a hemostatic in endoscopic sinus surgery. Ann Otol Rhinol Laryngol 114:699-704, 2005.
36. Green D. Spontaneous inhibitors to coagulation factors. Clin Lab Haematol 22(suppl 1):21-25, 2000.
37. Dorion RP, Hamati HF, Landis B, et al. Risk and clinical significance of developing antibodies induced by topical thrombin preparations. Arch Pathol Lab Med 122:887-894, 1998.
38. Flaherty MJ, Henderson R, and Wener MH. Iatrogenic immunization with bovine thrombin: A mechanism for prolonged thrombin times after surgery. Ann Intern Med 111: 631-634, 1989.
39. Ortel TL, Mercer MC, Thames EH, et al. Immunologic impact and clinical outcomes after surgical exposure to bovine thrombin. Ann Surg 233:88-96, 2001.
40. Valbonesi M. Fibrin glues of human origin. Best Pract Res Clin Haematol 19:191-203, 2006.
41. Frenkiel S, Desrosiers MY, and Nachtigal MD. Use of hylan B gel as a wound dressing after endoscopic sinus surgery. J Otolaryngol 31:41-44, 2002.
42. Bugten V, Nordgard S, and Steinsvag S. The effects of debridement after endoscopic sinus surgery. Laryngoscope 116:2037-2043, 2006.
43. Athanasiadis T, Beule A, Robinson B, et al. Effects of a novel chitosan gel on mucosal wound healing following endoscopic sinus surgery in a sheep model of chronic rhinosinusitis. Laryngoscope 118:1088-1094, 2008.
44. Yang J, Tian F, Wang Z, et al. Effect of chitosan molecular weight and deacetylation degree on hemostasis. J Biomed Mater Res B Appl Biomater 84:131-137, 2007.
45. Fukasawa M, Abe H, Masoaka T, et al. The hemostatic effect of deacetylated chitin membrane on peritoneal injury in rabbit model. Surg Today 22:333-338, 1992.