Biomaterials for sinus implantation

Current Opinion in Otolaryngology and Head and Neck Surgery

Volumn 15, Issue 1, 2007, Pages 44-47

  Orlandi, Richard R ^a,b,c  

^a Center for Therapeutic Biomaterials   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c NONE   (United States)

Author keywords

Biomaterials; Gelatin; Hyaluronan; Hydroxyapatite cement; Thrombin

Indexed keywords

BIOMATERIAL; COLLAGEN; GELATIN; GOLD; HYALURONIC ACID DERIVATIVE; HYDROXYAPATITE; METHACRYLIC ACID METHYL ESTER; PARAFFIN; POLITEF; SILASTIC; TANTALUM; THROMBIN; VITALLIUM; ZIRCONIUM;

ADHESION; BLEEDING; HUMAN; IMPLANTATION; NONHUMAN; PARANASAL SINUS DISEASE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; REVIEW; SCAR FORMATION; STENOSIS; TISSUE REGENERATION; WOUND HEALING;

ADJUVANTS, IMMUNOLOGIC; BIOCOMPATIBLE MATERIALS; ENDOSCOPY; HEMOSTATICS; HUMANS; HYALURONIC ACID; PARANASAL SINUSES; THROMBIN;

EID: 33846076199     PISSN: 10689508     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOO.0b013e328011bc9d     Document Type: Review

References (16)

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2. Verret DJ, Ducic Y, Oxford L, et al. Hydroxyapatite cement in craniofacial reconstruction. Otolaryngol Head Neck Surg 2005; 133:897-899. A review of complications from craniofacial use of hydroxyapatite cement, with an emphasis on frontal sinus obliteration.
3. Smith TL, Han JK, Loehrl TA, et al. Endoscopic management of the frontal recess in frontal sinus fractures: a shift in the paradigm? Laryngoscope 2002; 112:784-790.
4. Strong EB, Kellman RM. Endoscopic repair of anterior table-frontal sinus fractures. Facial Plast Surg Clin North Am 2006; 14:25-29. Presentation of a minimally invasive approach to 'camouflaging' anterior table defects using hydroxyapatite cement.
5. Weber R, Mai R, Hosemann W, et al. The success of 6-month stenting in endonasal frontal sinus surgery. Ear Nose Throat J 2000; 79:930-938.
6. Maccabee M, Hwang PH, Trune D. Effects of topically applied biomaterials on paranasal sinus mucosal healing. Am J Rhinol 2003; 17:203-207.
7. Chandra RK, Conley DB, Haines GK 3rd, et al. Long-term effects of FloSeal packing after endoscopic sinus surgery. Am J Rhinol 2005; 19:240-243. This paper presents at least 1-year follow up on patients receiving a thrombin-gelatin combination, raising concerns about scarring.
8. Tom LW, Palasti S, Potsic WP, et al. The effects of gelatin film stents in the middle meatus. Am J Rhinol 1997; 11:229-232.
9. Jameson M, Gross CW, Kountakis SE. FloSeal use in endoscopic sinus surgery: effect on postoperative bleeding and synechiae formation. Am J Otolaryngol 2006; 27:86-90. A prospective examination of thrombin-gelatin paste and its effects on bleeding and postoperative scarring.
10. Colwell AS, Longaker MT, Lorenz HP. Fetal wound healing. Front Biosci 2003; 8:S1240-S1248.
11. Border WA, Noble NA. Transforming growth factor beta in tissue fibrosis. N Engl J Med 1994; 331:1286-1292.
12. Rajapaksa SP, Cowin A, Adams D, et al. The effect of a hyaluronic acid-based nasal pack on mucosal healing in a sheep model of sinusitis. Am J Rhinol 2005; 19:572-576. A prospective study that examines re-epithelialization and scarring in a preoperatively inflamed sinus injury model.
13. Wormald PJ, Boustred RN, Le T, et al. A prospective single-blind randomized controlled study of use of hyaluronic acid nasal packs in patients after endoscopic sinus surgery. Am J Rhinol 2006; 20:7-10. A prospective randomized study examining the effect of a biomaterial on scarring and healing in humans following endoscopic sinus surgery.
14. Mehra TD, Ghosh K, Shu XZ, et al. Molecular stenting with a crosslinked hyaluronan derivative inhibits collagen gel contraction. J Invest Dermatol 2006; 126:2202-2209. An interesting potential explanation for the effects of hyaluronan on collagen molecular biology and scar contracture.
15. Orlandi RR, Li H, Shu XZ, et al. Preventing ostia closure during sinus surgery using in situ crosslinked HA hydrogels. In: Balazs EA, Hascall VC, editors. Hyaluronan: structure, metabolism, biological activities, therapeutic applications. Edgewater, NJ: Matrix Biology Institute; 2005. pp. 405-408.
16. Proctor M, Proctor K, Shu XZ, et al. Composition of hyaluronan affects wound healing in the rabbit maxillary sinus. Am J Rhinol 2006; 20:206-211. This study demonstrates the effect of differing modifications of the same starting material. Using an animal model of sinus wounding, both ostial diameter and histological examination showed significant differences in scarring and inflammation between the biomaterials. It clearly points out the importance of chemical composition and demonstrates the need for prospective evaluation of biomaterials.