Acute toxicity of some synthetic cyanogens in rats and their response to oral treatment with alpha-ketoglutarate

Food and Chemical Toxicology

Volumn 47, Issue 9, 2009, Pages 2314-2320

  Bhattacharya, R ^a   Satpute, R M ^a   Hariharakrishnan, J ^a   Tripathi, H ^b   Saxena, P B ^b  

^a DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

^b BIMR College of Life Sciences   (India)

Author keywords

Alpha ketoglutarate; Cyanogens; Oxidative stress; Protection; Toxicity

Indexed keywords

2 OXOGLUTARIC ACID; ACETONITRILE; ACRYLONITRILE; ALANINE; CYANIDE; CYTOCHROME C OXIDASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; MALONALDEHYDE; MALONONITRILE; NITRILE; NITROPRUSSIDE SODIUM; POTASSIUM ION; PROPIONITRILE; SUCCINONITRILE; THIOSULFATE SULFURTRANSFERASE; UNCLASSIFIED DRUG;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYANIDE POISONING; FEMALE; LD 50; NONHUMAN; OXIDATIVE STRESS; RAT;

ACUTE TOXICITY TESTS; ADMINISTRATION, ORAL; ANIMALS; ANTIDOTES; BLOOD CHEMICAL ANALYSIS; BRAIN; CYANIDES; FEMALE; KETOGLUTARIC ACIDS; KIDNEY; LETHAL DOSE 50; LIVER; NITRILES; OXIDATIVE STRESS; OXIDOREDUCTASES; POISONING; RATS; RATS, WISTAR; THIOCYANATES;

RATTUS;

EID: 67949110959     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.06.020     Document Type: Article

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