메뉴 건너뛰기




Volumn 19, Issue 1, 2006, Pages 61-66

Effect of α-ketoglutarate on cyanide-induced biochemical alterations in rat brain and liver

Author keywords

ketoglutarate; Gyanide; Hepatotoxicity; Neurotoxicity; Protection; Sodium thiosulfate

Indexed keywords

2 OXOGLUTARIC ACID; ALPHA-KETOGLUTARIC ACID; ANTIDOTE; CYTOCHROME C OXIDASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; POTASSIUM CYANIDE; SODIUM THIOSULFATE; SUPEROXIDE DISMUTASE; THIOSULFATE;

EID: 33645968434     PISSN: 08953988     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (12)

References (37)
  • 1
    • 0021287514 scopus 로고
    • Cyanide intoxication and its mechanism of antagonism
    • Way J L (1984). Cyanide intoxication and its mechanism of antagonism. Ann Rev Pharmacol Toxicol 24, 451-481.
    • (1984) Ann Rev Pharmacol Toxicol , vol.24 , pp. 451-481
    • Way, J.L.1
  • 2
    • 0000846556 scopus 로고
    • Toxicodynamics of cyanide
    • (S M Somani, Ed), Academic Press, California
    • Borowitz J L, Kanthasamy A G, Isom G E (1992). Toxicodynamics of cyanide. In Chemical Warfare Agents (S M Somani, Ed), Academic Press, California, pp 209-236.
    • (1992) Chemical Warfare Agents , pp. 209-236
    • Borowitz, J.L.1    Kanthasamy, A.G.2    Isom, G.E.3
  • 3
    • 0002259350 scopus 로고
    • Toxicology of cyanide
    • (B Ballantyne and T C Marrs, Eds.), Wright Publishers, Bristol
    • Ballantyne B (1987). Toxicology of cyanide. In Clinical and Experimental Toxicology of Cyanides (B Ballantyne and T C Marrs, Eds.), Wright Publishers, Bristol, pp. 61.
    • (1987) Clinical and Experimental Toxicology of Cyanides , pp. 61
    • Ballantyne, B.1
  • 4
    • 0002854939 scopus 로고
    • A degenerative neuropathy with blindness and chronic cyanide intoxication of dietary origin. The evidence in Nigerians
    • (R L Smith, E A Bababunmi, Eds.), Taylor & Francis, London
    • Osuntokun B O (1980). A degenerative neuropathy with blindness and chronic cyanide intoxication of dietary origin. The evidence in Nigerians. In Toxicology in the Tropics (R L Smith, E A Bababunmi, Eds.), Taylor & Francis, London, pp 16-79.
    • (1980) Toxicology in the Tropics , pp. 16-79
    • Osuntokun, B.O.1
  • 5
    • 0025730878 scopus 로고
    • Toxicokinetics aspects of chronic cyanide exposure in the rat
    • Leuschner J, Winkler A, Leuschner F (1991). Toxicokinetics aspects of chronic cyanide exposure in the rat. Toxicol Letts 57, 195-201.
    • (1991) Toxicol Letts , vol.57 , pp. 195-201
    • Leuschner, J.1    Winkler, A.2    Leuschner, F.3
  • 6
    • 0032810408 scopus 로고    scopus 로고
    • Liver and kidney lesions and associated enzyme changes induced in rabbits by chronic cyanide exposure
    • Okolie N P, Osagie A U (1999). Liver and kidney lesions and associated enzyme changes induced in rabbits by chronic cyanide exposure. Food Chem Toxicol 37, 745-750.
    • (1999) Food Chem Toxicol , vol.37 , pp. 745-750
    • Okolie, N.P.1    Osagie, A.U.2
  • 7
    • 0022498583 scopus 로고
    • Industrial exposure to hydrogen cyanide: Implications for treatment
    • Peden N R, Taha A, McSorley P D, et al. (1986). Industrial exposure to hydrogen cyanide: Implications for treatment. Br Med J 293, 538.
    • (1986) Br Med J , vol.293 , pp. 538
    • Peden, N.R.1    Taha, A.2    McSorley, P.D.3
  • 8
    • 0026409360 scopus 로고
    • Elevated blood cyanide concentrations in victims of smoke inhalation
    • Baud F J, Barriot P, Toffis V, et al. (1991). Elevated blood cyanide concentrations in victims of smoke inhalation. New Eng J Med 325, 1761-1766.
    • (1991) New Eng J Med , vol.325 , pp. 1761-1766
    • Baud, F.J.1    Barriot, P.2    Toffis, V.3
  • 9
    • 0000306153 scopus 로고
    • Nitrite and thiosulphate therapy in cyanide poisoning
    • Chen K K, Rose C L (1952). Nitrite and thiosulphate therapy in cyanide poisoning. J A M A 149, 113-119.
    • (1952) J A M A , vol.149 , pp. 113-119
    • Chen, K.K.1    Rose, C.L.2
  • 10
    • 77957180595 scopus 로고
    • Cyanide antagonism
    • Way, J L (1983). Cyanide antagonism. Fund. Appl Toxicol 3, 383-386.
    • (1983) Fund. Appl Toxicol , vol.3 , pp. 383-386
    • Way, J.L.1
  • 11
    • 0026608991 scopus 로고
    • The antidotal action of sodium nitrite and sodium thiosulphate against cyanide poisoning
    • Baskin S I, Horowitz A M, Nealley E W (1992). The antidotal action of sodium nitrite and sodium thiosulphate against cyanide poisoning. J Clin Pharmacol 32, 368-375.
    • (1992) J Clin Pharmacol , vol.32 , pp. 368-375
    • Baskin, S.I.1    Horowitz, A.M.2    Nealley, E.W.3
  • 13
    • 0024605427 scopus 로고
    • Suspected cyanide poisoning in smoke inhalation: Complications of sodium nitrite therapy
    • Hall A H, Kulig K W, Rumack B H (1989). Suspected cyanide poisoning in smoke inhalation: complications of sodium nitrite therapy. J Toxicol Clin Expts 9, 3-9.
    • (1989) J Toxicol Clin Expts , vol.9 , pp. 3-9
    • Hall, A.H.1    Kulig, K.W.2    Rumack, B.H.3
  • 15
    • 0018612842 scopus 로고
    • Antagonism of cyanide intoxication with sodium pyruvate
    • Schwartz C, Morgan R L, Way L M, et al. (1979). Antagonism of cyanide intoxication with sodium pyruvate. Toxicol Appl Pharmacol 50, 437-441.
    • (1979) Toxicol Appl Pharmacol , vol.50 , pp. 437-441
    • Schwartz, C.1    Morgan, R.L.2    Way, L.M.3
  • 16
    • 0022620707 scopus 로고
    • The efficacy of α-ketoglutaric acid in the antagonism of cyanide intoxication
    • Moore S J, Norris J C, HO I K, et al. (1986). The efficacy of α-ketoglutaric acid in the antagonism of cyanide intoxication. Toxicol Appl Pharmacol 82, 40-44.
    • (1986) Toxicol Appl Pharmacol , vol.82 , pp. 40-44
    • Moore, S.J.1    Norris, J.C.2    Ho, I.K.3
  • 17
    • 0025186417 scopus 로고
    • Efficacy of alpha-ketoglutaric acid as an effective antidote in cyanide poisoning in dogs
    • Dalvi R R, Sawant S G, Terse P S (1990). Efficacy of alpha-ketoglutaric acid as an effective antidote in cyanide poisoning in dogs. Vet Res Commu 14, 411-414.
    • (1990) Vet Res Commu , vol.14 , pp. 411-414
    • Dalvi, R.R.1    Sawant, S.G.2    Terse, P.S.3
  • 18
    • 0026038393 scopus 로고
    • Protection against cyanide toxicity by oral alpha- Ketoglutaric acid
    • Dulaney M D (Jr), Brumely M, Willis J T, et al. (1991). Protection against cyanide toxicity by oral alpha- ketoglutaric acid. Vet Human Toxicol 33, 571-575.
    • (1991) Vet Human Toxicol , vol.33 , pp. 571-575
    • Dulaney Jr., M.D.1    Brumely, M.2    Willis, J.T.3
  • 19
    • 0025346074 scopus 로고
    • Mechanism of antagonising cyanide induced lethality by α-ketoglutaric acid
    • Norris J C, Utley W A, Hume A S (1990). Mechanism of antagonising cyanide induced lethality by α-ketoglutaric acid. Toxicology 64, 275-283.
    • (1990) Toxicology , vol.64 , pp. 275-283
    • Norris, J.C.1    Utley, W.A.2    Hume, A.S.3
  • 20
    • 0026294605 scopus 로고
    • Cyanide intoxication in mice through different routes and its prophylaxis by α-ketoglutarate
    • Bhattacharya R, Vijayaraghavan R (1991). Cyanide intoxication in mice through different routes and its prophylaxis by α-ketoglutarate. Biomed Environ Sci 4, 452-460.
    • (1991) Biomed Environ Sci , vol.4 , pp. 452-460
    • Bhattacharya, R.1    Vijayaraghavan, R.2
  • 21
    • 0036591615 scopus 로고    scopus 로고
    • Promising role of α-ketoglutarate in protecting against the lethal effects of cyanide
    • Bhattacharya R, Vijayaraghavan R (2002). Promising role of α-ketoglutarate in protecting against the lethal effects of cyanide. Human Exp Toxicol 21, 297-303.
    • (2002) Human Exp Toxicol , vol.21 , pp. 297-303
    • Bhattacharya, R.1    Vijayaraghavan, R.2
  • 22
    • 0037051165 scopus 로고    scopus 로고
    • In vitro and in vivo attenuation of experimental cyanide poisoning by α-ketoglutarate
    • Bhattacharya R, Lakshmana Rao P V, Vijayaraghavan R (2002). In vitro and in vivo attenuation of experimental cyanide poisoning by α-ketoglutarate. Toxicol Letts 128, 185-195.
    • (2002) Toxicol Letts , vol.128 , pp. 185-195
    • Bhattacharya, R.1    Lakshmana Rao, P.V.2    Vijayaraghavan, R.3
  • 23
    • 0024373875 scopus 로고
    • Brain lipid peroxidation and antioxidant protectant mechanisms following acute cyanide intoxication
    • Ardelt B K, Borowitz J L, Isom G E (1989). Brain lipid peroxidation and antioxidant protectant mechanisms following acute cyanide intoxication. Toxicology 56, 147-154.
    • (1989) Toxicology , vol.56 , pp. 147-154
    • Ardelt, B.K.1    Borowitz, J.L.2    Isom, G.E.3
  • 24
    • 0023265078 scopus 로고
    • Peroxidation of brain lipids following cyanide intoxication in mice
    • Johnson J D, Conroy W G, Burris K D, et al. (1987). Peroxidation of brain lipids following cyanide intoxication in mice. Toxicology 46, 21-28.
    • (1987) Toxicology , vol.46 , pp. 21-28
    • Johnson, J.D.1    Conroy, W.G.2    Burris, K.D.3
  • 25
    • 0028305506 scopus 로고
    • Cyanide-induced lipid peroxidation in different organs: Subcellular distribution and hydroperoxide generation in neuronal cells
    • Ardelt B K, Borowitz J L, Maduh E U, et al. (1994). Cyanide-induced lipid peroxidation in different organs: subcellular distribution and hydroperoxide generation in neuronal cells. Toxicology 89, 127-137.
    • (1994) Toxicology , vol.89 , pp. 127-137
    • Ardelt, B.K.1    Borowitz, J.L.2    Maduh, E.U.3
  • 26
    • 0037166046 scopus 로고    scopus 로고
    • Does prolonged oral exposure to cyanide promote hepatotoxicity and nephrotoxicity?
    • Sousa A B, Soto-Blanco B, Guerra J L, et al. (2002). Does prolonged oral exposure to cyanide promote hepatotoxicity and nephrotoxicity? Toxicology 174, 87-95.
    • (2002) Toxicology , vol.174 , pp. 87-95
    • Sousa, A.B.1    Soto-Blanco, B.2    Guerra, J.L.3
  • 27
    • 78651001645 scopus 로고
    • Microspectrophotometric method for the determination of cytochrome oxidase
    • Cooperstein S J, Lazarow A A (1951). Microspectrophotometric method for the determination of cytochrome oxidase. J Biol Chem 189, 665-670.
    • (1951) J Biol Chem , vol.189 , pp. 665-670
    • Cooperstein, S.J.1    Lazarow, A.A.2
  • 28
    • 0017064979 scopus 로고
    • Fluorometric method for determination of oxidized and reduced glutathione in tissues
    • Hissin P J, Hilf R A (1976). Fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal Biochem 74, 214-226.
    • (1976) Anal Biochem , vol.74 , pp. 214-226
    • Hissin, P.J.1    Hilf, R.A.2
  • 29
    • 29744466425 scopus 로고
    • Determination of serum proteins by means of the biuret reaction
    • Gornall A G, Bardawell C J, David M M (1948). Determination of serum proteins by means of the biuret reaction. J Biol Chem 177, 751-766.
    • (1948) J Biol Chem , vol.177 , pp. 751-766
    • Gornall, A.G.1    Bardawell, C.J.2    David, M.M.3
  • 30
    • 0016742296 scopus 로고
    • Toxicological and clinical aspects of cyanide metabolism
    • Baumeister R G H, Schievelbein H, and Zickgraf-Rudel G (1975). Toxicological and clinical aspects of cyanide metabolism. Drug Res 25, 1056-1063.
    • (1975) Drug Res , vol.25 , pp. 1056-1063
    • Baumeister, R.G.H.1    Schievelbein, H.2    Zickgraf-Rudel, G.3
  • 31
    • 0017564793 scopus 로고
    • Acute cyanide poisoning complicated lactic acidosis and pulmonary edema. Arch
    • Grahm D L, Laman D, Theodore J, et al. (1977). Acute cyanide poisoning complicated lactic acidosis and pulmonary edema. Arch. Intern Med 137, 1051-1055.
    • (1977) Intern Med , vol.137 , pp. 1051-1055
    • Grahm, D.L.1    Laman, D.2    Theodore, J.3
  • 32
    • 0028001691 scopus 로고
    • Prevention of cyanide-induced cytotoxicity by nutrients in isolated rat hepatocytes
    • Niknahad H, Khan S, Sood C, et al. (1994). Prevention of cyanide-induced cytotoxicity by nutrients in isolated rat hepatocytes. Toxicol Appl Pharmacol 128, 271-279.
    • (1994) Toxicol Appl Pharmacol , vol.128 , pp. 271-279
    • Niknahad, H.1    Khan, S.2    Sood, C.3
  • 33
    • 0027411707 scopus 로고
    • Protection against cyanide poisoning by co-administration of sodium nitrite and hydroxylamine in rats
    • Bhattacharya R, Jeevaratnam K, Raza, S K, et al. (1993). Protection against cyanide poisoning by co-administration of sodium nitrite and hydroxylamine in rats. Human Exp Toxicol 12, 33-36.
    • (1993) Human Exp Toxicol , vol.12 , pp. 33-36
    • Bhattacharya, R.1    Jeevaratnam, K.2    Raza, S.K.3
  • 34
    • 0028176512 scopus 로고
    • Protection of cytochrome c oxidase against cyanide inhibition by pyruvate and α-ketoglutarate: Effect of aeration in vitro
    • Delhumeau G, Cruz-Mendoza A M, Lozero C G (1994). Protection of cytochrome c oxidase against cyanide inhibition by pyruvate and α-ketoglutarate: Effect of aeration in vitro. Toxicol Appl Pharmacol 126, 345-351.
    • (1994) Toxicol Appl Pharmacol , vol.126 , pp. 345-351
    • Delhumeau, G.1    Cruz-Mendoza, A.M.2    Lozero, C.G.3
  • 35
    • 0035666709 scopus 로고    scopus 로고
    • Cholestatic hepatitis caused by acute gold potassium cyanide poisoning
    • Wung M-L, Tsai W-J, Ger J, et al. (2001). Cholestatic hepatitis caused by acute gold potassium cyanide poisoning. Clin Toxicol 7, 739-743.
    • (2001) Clin Toxicol , vol.7 , pp. 739-743
    • Wung, M.-L.1    Tsai, W.-J.2    Ger, J.3
  • 36
    • 0025210582 scopus 로고
    • Protection against cyanide induced convulsions with α-ketoglutarate
    • Yamamoto H-A (1990). Protection against cyanide induced convulsions with α-ketoglutarate. Toxicology 61, 221-228.
    • (1990) Toxicology , vol.61 , pp. 221-228
    • Yamamoto, H.-A.1
  • 37
    • 0035195474 scopus 로고    scopus 로고
    • Acute toxicity studies of α-ketoglutarate: A Promising antidote for cyanide poisoning
    • Bhattacharya R, Kumar D, Sugendran K, et al. (2001). Acute toxicity studies of α-ketoglutarate: A Promising antidote for cyanide poisoning. J Appl Toxicol 21, 495-499.
    • (2001) J Appl Toxicol , vol.21 , pp. 495-499
    • Bhattacharya, R.1    Kumar, D.2    Sugendran, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.